Abstract Background Excision of the mesopancreas with lymphadenectomy is an important component of pancreatoduodenectomy. However, the optimal extent of lymphadenectomy remains unclear. Furthermore, accurate description of the mesopancreatic lymphatic pathways is difficult, probably because of the complex anatomy. Intestinal derotation simplifies the anatomy and facilitates both examination of lymphatic flow and the surgical procedure....
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In Australia and Sweden, orthodontic treatments may be performed by either a general dental practitioner (GDP) or a specialist orthodontist. Evidence suggests that the public may easily confuse a GDP who provides orthodontic treatment with a specialist orthodontist. We conducted a survey of people in Australia and Sweden to assess their understanding of the differences between a specialist orthodontist and a GDP who provides orthodontic treatments.
One factor that can affect treatment outcomes is the treatment provider, and this factor has not been extensively studied. This research aimed to evaluate orthodontic treatment quality, length, and efficiency when 2 orthodontists collaborated on treatment, compared with the treatment provided solely by either orthodontist.
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There is limited evidence linking achievement of biochemical response with outcomes in Autoimmune Hepatitis (AIH), and it is unclear whether normalization of serum immunoglobulin G (IgG) levels influences prognosis.
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The COVID-19 pandemic has had significant global consequences, with healthcare systems stretched to their limits, a growing death toll, and economic devastation as economies came grinding to a halt. The pandemic and its aftereffects will be with us for some time to come, but this isn’t the first pandemic humanity has weathered, and it won’t be the last. Given accelerating advances in medical technology, there is plenty to discuss in terms of how we can be better prepared for the next infectious...
Researchers at Hokkaido University in Japan have developed a microfluidic test that can detect antibodies against a viral infection. So far, the test has been optimized to detect avian flu, but could be adapted to detect antibodies against the virus causing COVID-19. The device can provide a result in as little as 20 minutes and requires only 2 microliters of serum to run. Antibody tests have been proposed as a way to determine how many people have been exposed to COVID-19, and may help...
Researchers from Penn State and Stanford University have developed a 30-minute urine test to measure levels of substances that can contribute to kidney stone formation. The test could help patients to find out if they are prone to developing kidney stones or to monitor their progress in avoiding kidney stone formation through treatment or dietary changes. Kidney stones are accumulations of crystallized substances such as minerals and salts, and the stones can cause pain and blockages...
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Exosomes are small membrane vesicles that retain various substances such as proteins, nucleic acids, and small RNAs. Exosomes play crucial roles in many physiological and pathological processes, including innate immunity. Innate immunity is an important process that protects the organism through activating pattern recognition receptors (PRRs), which then can induce inflammatory factors to resist pathogen invasion. Toll-like receptor (TLR) is one member of PRRs and is important in pathogen clearance...
Objective. To analyze the potential role of colchicine monotherapy in patients with tumor necrosis factor receptor associated periodic syndrome (TRAPS) in terms of control of clinical and laboratory manifestations. Methods. Patients with TRAPS treated with colchicine monotherapy were retrospectively enrolled; demographic, clinical and therapeutic data were collected and statistically analysed after having clustered patients according to different times at disease onset, penetrance of mutations, dosage...
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The aim of this study was to compare the efficacy and safety of the different local anaesthetic agents for the extraction of impacted lower third molars. A network meta-analysis was performed of all published reports of randomized controlled clinical trials assessing efficacy (anaesthetic success and absence of need for supplementary anaesthesia during the surgical procedure) and/or safety (number of adverse events) of anaesthetic agents. Three electronic databases were searched, from their earliest...
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Abstract To examine clinical outcomes for combination therapy of heparin-bonded covered stent [VIABAHN™ stent (VIA)] and bare-nitinol stent (BNS), and to determine independent predictors of restenosis after VIA implantation assessed by intravascular ultrasound (IVUS). A retrospective analysis was conducted on VIA use in the femoropopliteal artery of 71 patients (81 lesions) treated between June 2012 and November 2018. We divided the treated lesions into two groups; that is, whether...
Abstract Systemic congestion is one of the mechanisms involved in acute decompensated heart failure (ADHF). Increased intra-abdominal pressure (IAP), elicited by abdominal congestion, has been related to acute kidney injury and prognosis. Nonetheless, the link between diuretic response, surrogate markers of congestion and renal function remains poorly understood. We measured IAP in 43 patients from a non-interventional, exploratory, prospective, single center study carried out...
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Abstract Background Advances in modern spinal fusion techniques have allowed for less peri-operative morbidity and more rapid recovery from surgery. The addition of endoscopy to minimally invasive surgery (MIS) fusion techniques represents the latest progression of efforts to minimize the impact of surgical intervention. Technique MIS transforaminal...
Abstract Background Sacral fractures and failures are uncommon after lumbosacral fusion but have received increasing attention in the surgical literature. They can be difficult to diagnose, making timely treatment difficult. No consensus has been reached on the characteristics of these complications or on optimal treatment. Questions/Purposes ...
Abstract Background Lumbar interbody fusion is among the most common types of spinal surgery performed. Over time, the term has evolved to encompass a number of different approaches to the intervertebral space, as well as differing implant materials. Questions remain over which approaches and materials are best for achieving fusion and restoring disc height. Questions/Purposes...
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Abstract The biogenic tailoring of silver nanoparticles using plant extract is becoming an attractive approach in the current scenario. Manilkara zapota (MZ) is well known for its antibacterial, hepato-protective, anti-inflammatory, anti-tussive, anti-fungal, anti-tumour, and free radical scavenging potential. Its plants extract is a rich source of secondary metabolites. Nowadays, silver nanoparticles (AgNPs) have been advocated for a variety of biomedical applications. In present...
Abstract This study aimed to determine the ability of Fusarium verticillioides in developing mechanisms to counteract the antifungal effect of a fraction from Jacquinia macrocarpa plant extract (JmAF), as well as the morphological and physiological changes that occur during its exposure. The fungus was exposed to JmAF during consecutive periods. A culture sample was taken weekly to determine radial growth, spore germination and size, and fungal β-1,3-glucanase activity. The results...
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Oral rehabilitation after treatment for head and neck cancer can be challenging. Implant-supported rehabilitation can considerably improve oral health-related quality of life, but there is a dearth of contemporary evidence of reported outcomes and trends in this cohort. In this study we retrospectively investigated the outcomes of 115 patients (376 dental implants) with a mean (range) follow up of 3.91(0.11-12.76) years. We considered survival of the implants, percentage of those used for prosthetic...
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Abstract Aim To describe the MR and CT imaging features of organized hematomas [OH]. Methods A retrospective analysis of MR imaging and CT of eight patients [6 male, 2 females; age range is 6–86 years] with pathological proven OH was performed. Routine contrast MR and CT scan were done for all patients, and diffusion-weighted imaging and dynamic contrast...
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Fibrous dysplasia is an unusual pathologic condition caused by abnormal bone metabolism. Temporal bone involvement is often seen, but it is uncommon to find fibrous dysplasia limited to the middle ear, especially originating in and confined to a single ossicle. Here we report a case of osteofibrous dysplasia limited exclusively to an ossicle (malleus) causing gradual conductive hearing loss, which recovered after eventual complete removal of the dysplastic area. The lesion showed firm attachment...
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Publication date: Available online 26 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Tatsurou Tanaka, Ray Tanaka, Andy Wai Kan Yeung, Michael M Bornstein, Shun Nishimura, Masafumi Oda, Manabu Habu, Osamu Takahashi, Daigo Yoshiga, Teppei Sago, Ikuya Miyamoto, Masaaki Kodama, Nao Wakasugi-Sato, Shinobu Matsumoto-Takeda, Takaaki Joujima, Yuichi Miyamura, Yasuhiro Morimoto
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Publication date: Available online 27 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Nazan Degirmenci, Selahattin Tugrul, Seda Sezen Goktas, Erol Senturk, Omer Faruk Calim, Remzi Dogan, Alper Yenigun, Orhan Ozturan
Publication date: Available online 27 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Leila Chew, Brooke M. Su-Velez, Jessa E. Miller, Alisha N. West
Publication date: Available online 26 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Nigel Wang, Glenn Isaacson
Publication date: Available online 26 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Leila Ghayedlou, Akram Ahmadi, Ali Ghorbani, Farhad Torabinezhad, Mohammad Reza Keyhani, Seyed Basir Hashemi
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Publication date: Available online 26 May 2020Source: NeuroImageAuthor(s): Wei Xiong, Xiaoxue Gao, Zhewen He, Hongbo Yu, Huiying Liu, Xiaolin Zhou
Publication date: Available online 26 May 2020Source: NeuroImageAuthor(s): Joaquim Radua, Eduard Vieta, Russell Shinohara, Peter Kochunov, Yann Quidé, Melissa Green, Cynthia Weickert, Thomas Weickert, Jason Bruggemann, Tilo Kircher, Igor Nenadic, Murray Cairns, Marc Seal, Ulrich Schall, Frans Henskens, Janice Fullerton, Bryan Mowry, Christos Pantelis, Rhoshel Lenroot, Vanessa Cropley
Publication date: Available online 26 May 2020Source: NeuroImageAuthor(s): Daouia I. Larabi, Remco J. Renken, Joana Cabral, Jan-Bernard C. Marsman, André Aleman, Branislava Ćurčić-Blake
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Publication date: Available online 27 May 2020Source: Oral OncologyAuthor(s): Maryam Baghizadeh Fini
Publication date: Available online 26 May 2020Source: Oral OncologyAuthor(s): Abhinav Thaduri, Amit Sehrawat, Dharma Ram Poonia, Mahendra Pal Singh, Nilotpal Chowdhury
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Abstract Background A synapse is a fundamental signaling component that facilitates neuronal connectivity and information processing in the brain. Dynamic changes in the number, size, and functionality of synapse are induced by extensive signaling networks and structural proteins, which are stimulated on various neuronal activities. Changes in the expression level of synaptic proteins depend upon the physiological and pathological conditions...
Abstract Background p-Coumaric acid (p-CA), a phenolic compound abundantly found in edible plants, was found to induce apoptosis in SNU-16 gastric cancer cells. However, the effects of p-CA on the microRNA expression pattern in SNU-16 cells have not been reported. Objectives The primary objective of this study was to investigate microRNA expression...
Abstract Background Anti-Müllerian hormone (Amh) plays a critical role in both early sex determination and later gonad development in vertebrate species. However, it remains unknown in northern snakehead (Channa argus), which is economically important freshwater fish with sexual dimorphism. Objective This study aimed to identify the expression profiles...
Abstract Background The flathead grey mullet, Mugil cephalus has a global distribution in tropical, subtropical and temperate seas worldwide. Previous studies proposed that globally distributed M. cephalus comprises at least 14 different lineages, and divided into two or three groups in the northwest Pacific. Therefore, we hypothesized that there may exist at least two lineages in Korea. ...
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