Reconstructing forked corpus spongiosum to correct glans droop in distal/midshaft hypospadias repair
Journal of International Medical Research, Volume 48, Issue 5, May 2020. PurposeWe reviewed our experience and efficacy of reconstruction of a forked corpus spongiosum (FCS) to correct glans droop in distal/midshaft hypospadias repair.MethodsEighty-five consecutive patients who underwent distal/midshaft hypospadias repair by the same surgeon in our center from October 2015 to June 2018 were retrospectively analyzed. All cases were accompanied by different degrees of glans droop, which we corrected...
Wed May 27, 2020 05:44
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveWe investigated the “BURP” maneuver’s effect on the association between difficult laryngoscopy and difficult intubation, and predictors of a difficult airway.MethodsAdult patients who underwent general anesthesia and tracheal intubation from September 2016 to May 2018 were included. The “BURP” maneuver was performed when glottic exposure was classified as Cormack–Lehane grade 3 or 4, suggesting difficult laryngoscopy....
Wed May 27, 2020 05:36
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveAs a minimally invasive intervertebral fusion technique popularized in recent years, extreme lateral interbody fusion (XLIF) has various advantages. In this study, we describe the application and efficacy of XLIF for the treatment of thoracic tuberculosis (TB), as this may be an emerging treatment option for thoracic TB in the future.MethodsWe present the case of a 75-year-old man who had suffered from chest and back...
Wed May 27, 2020 05:22
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study was performed to compare the clinical outcomes and performance of the collum femoris-preserving (CFP) stem (Waldemar Link GmbH & Co., Hamburg, Germany) and the Tri-Lock stem (DePuy Orthopaedics, Warsaw, IN, USA) in terms of femoral offset (FO) and leg length reconstruction.MethodsClinical and radiographic data of patients who underwent total hip arthroplasty with either a CFP stem or Tri-Lock stem from...
Wed May 27, 2020 05:17
Journal of International Medical Research, Volume 48, Issue 5, May 2020. BackgroundThoracogastric airway fistula (TGAF) is a serious complication of esophagectomy for esophageal cancer. We conducted a systematic review of the appropriate therapeutic options for acquired TGAF.MethodsWe performed a literature search to identify relevant studies from PubMed, EMBASE, and Web of Science using the search terms “gastric airway fistula”, “gastrotracheal fistula”, “gastrobronchial fistula”, “tracheogastric...
Wed May 27, 2020 05:07
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo compare the knee shape and bone parameters between knee prosthesis products from overseas companies and a Chinese patient’s knee, and to apply the anatomical basis for Chinese knee prosthesis design.MethodsThree-dimensional digital models were built, including prosthesis products for a normal adult. The relevant anatomy index was measured, and physical parameter, radiographic, geometric, knee kinematic, and distal...
Wed May 27, 2020 04:31
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectivesTo investigate the effects of early administration of tirofiban after intravenous thrombolysis on early neurological deterioration in patients with branch atheromatous disease.MethodsWe analyzed clinical data from patients with branch atheromatous disease. We enrolled seven cases into the urokinase-only (UO) control group and 10 cases into the urokinase + tirofiban (UT) treatment group. National Institutes of Health...
Wed May 27, 2020 04:30
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Cronkhite–Canada syndrome is rarely encountered in clinical practice. Notably, most patients with Cronkhite–Canada syndrome exhibit hypoalbuminemia. Because the cause of Cronkhite–Canada syndrome is unknown, no specific treatment method has been established. Here, we describe a 59-year-old woman with Cronkhite–Canada syndrome in whom clinical manifestations were considerably relieved after treatment with prednisone.
Wed May 27, 2020 04:27
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveWe aimed to explore differences in the educational impact of the mini-Clinical Evaluation Exercise (mini-CEX) on resident (RE) and professional degree postgraduate (PDPG) trainees, as well as influencing factors, to provide suggestions for hospital managers, trainers, and trainees.MethodsWe performed a retrospective analysis of all scores among first-year resident standardization training trainees registered during...
Wed May 27, 2020 04:22
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study reports clinical characteristic of moderate–severe obsessive–compulsive disorder (OCD) among school students in China.MethodsWe examined 153 patients for the distribution of OCD symptoms using the Yale-Brown Obsessive Compulsive Scale Symptoms Checklist, the severity of anxiety and depression symptoms using the Hamilton Anxiety Scale and the Hamilton Depression Scale-24, respectively, and impairment in learning,...
Wed May 27, 2020 14:59
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo investigate the associations between serum vitamin D, calcium and uterine fibroids in a Chinese female population.MethodsIn this case-control study, adult female patients with fibroids (cases) were compared with females without fibroids (controls) in terms of serum 25-hydroxyvitamin D (25OHD) and calcium levels.ResultsOut of 546 total participants (mean age, 41.68 ± 5.99 years; 279 with fibroids and 267 without fibroids),...
Wed May 27, 2020 14:56
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis prospective study was performed to investigate the distribution of proximal ulnar artery perforating vessels through three-dimensional blood vessel reconstruction and examine the presence and consistency of the perforating vessels intraoperatively.MethodsFor anatomical guidance, three-dimensional blood vessel reconstruction was performed to determine the consistent presence of perforating vessels in the proximal...
Wed May 27, 2020 04:05
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Here, we report a case of coexistence of a duplicate gallbladder and choledochal cyst, which was overlooked preoperatively and confirmed via intraoperative inspection and pathological examination. We concluded that a high index of suspicion is required to diagnose a double gallbladder, and special attention should be paid to preoperative radiological imaging when treating patients with choledochal cysts because these patients...
Wed May 27, 2020 12:58
בארכיון האקדמיה מצאנו מכתב משנת 1940 אל ועד הלשון המעיד על התשוקה שבערה ביישוב העברי בארץ ישראל המנדטורית לשפה העברית. הפונה הוא ד"ר קורט רוזנטל מתל אביב, עולה חדש מגרמניה, שמבקש להביע את תמיכתו במאבק של ועד הלשון נגד "העלונות בשפה הגרמנית" (העלונים). ד"ר רוזנטל מציג את עצמו: "גם אני עולה מגרמניה ובאתי ארצה לפני עשרה חודשים. אני ציוני שלושים שנה ויודע היטב מאד, שלשפה העברית ורק לשפה העברית יכולה להיות רשות להישמע בארצנו ואין פה המקום להצדיק את האנשים האלה, שקונים וקוראים את העלונות הגרמניות [העלונים...
Wed May 27, 2020 14:03
"בבית הספר יש בערך כאלף תלמידים". "תקציב המדינה לשנה זו הוא בערך כארבע מאות מיליארד שקלים". ניסוחים דוגמת אלו רווחים בציבור ואפילו נקרים פה ושם בכלי התקשורת, ואולם הם אינם תקינים. המילה בערך והמילית כ־ שוות במשמען בהקשר זה לציון קירוב או אומדן, אך הבאתן זו לצד זו היא כפילות שאין לה יסוד. לפי זה הניסוח התקין הוא – בבית הספר יש כאלף תלמידים. / בבית הספר יש בערך אלף תלמידים. תקציב המדינה לשנה זו הוא כארבע מאות מיליארד שקלים. / תקציב המדינה לשנה זו הוא בערך ארבע מאות מיליארד שקלים. כְּ־ המילית...
Wed May 27, 2020 14:07
"היזהר! הכביש מלא מַהֲמוֹרוֹת!" שימו לב – מַהֲמוֹרָה ומַהֲמוֹרוֹת בחולם (מלא), ולא "מַהֲמוּרָה" ו"מַהֲמוּרוֹת" בשורוק. מהמורה היא מילה יחידאית בתנ"ך ובאה רק בצורת הרבים: "יִמּוֹטוּ (ימיטו) עֲלֵיהֶם גֶּחָלִים בָּאֵשׁ יַפִּלֵם בְּמַהֲמֹרוֹת בַּל יָקוּמוּ" (תהלים קמ, יא). מפרשי המקרא פירשו על פי ההקשר – "שׁוּחוֹת עמוקות", וחלקם אף ציינו את היקרותה בתלמוד הירושלמי במובן 'בור בקרקע המשמש קבר': "בראשונה היו קוברין אותן במהמורות, נתאכל הבשר היו מלקטין את העצמות וקוברין אותן ברזים [=בארזים]" (מועד קטן...
Wed May 27, 2020 13:35
נשאלנו: האם יום י"ח באייר – היום השלושים ושלושה לספירת העומר – הוא ל"ג לעומר או ל"ג בעומר? שני האופנים לכינויו של היום מתועדים בספרות פוסקי ההלכה כבר בימי הביניים (למן המאה הי"ג ואילך). במסורת קהילות המזרח היום מכונה לָ"ג לעומר, ובקהילות יוצאי אשכנז הוא נקרא ל"ג בעומר. מסתבר ששמו של היום תלוי בנוסח ספירת העומר בקהילות ישראל. בנוסח קהילות המזרח ומקצת קהילות האשכנזים נוהגים לספור 'היום כך וכך לעומר', ואילו בנוסח רוב יהודי אירופה 'היום כך וכך בעומר'. ההבדל בין הנוסחים נובע מהבדל בתפיסת המושג עומר:...
Wed May 27, 2020 13:32
ובמילים עבריות ולועזיות אחדות מופיעה בראש המילה אל"ף שאינה חלק מן המילה. למשל: לצד המילה תְּמוֹל יש אֶתְמוֹל, והפילוסוף היווני הנודע Πλάτων (באותיות לטיניות: Platon) היה בעברית לאפלטון. מה ההסבר להופעת האל"ף הזאת? אל"ף זו מכונה בלועזית אל"ף פרוסתטית (prosthetic aleph), והמונח העברי שנקבע לה הוא אל"ף מַקדימה.[1] מדובר באל"ף (ואולי רק בתנועה) שנוספת למילה בתחילתה מטעמי הגייה. תוספת אל"ף כזאת ידועה גם משפות שמיות אחרות, דוגמת ארמית וערבית,[2] ותוספת של תנועה מקדימה – גם משפות אירופיות. התופעה בולטת...
Wed May 27, 2020 13:13
שַׁחַר הוא שמם המקראי של דמדומי הבוקר, קרני השמש הראשונות. הופעת השחר בראשית היום מתוארת בדרך כלל בפועל עָלָה: "וַיִּוָּתֵר יַעֲקֹב לְבַדּוֹ וַיֵּאָבֵק אִישׁ עִמּוֹ עַד עֲלוֹת הַשָּׁחַר (בראשית לה, כה); "וַיֹּאמֶר שַׁלְּחֵנִי כִּי עָלָה הַשָּׁחַר" (שם, כז); "וַיְמַן הָאֱ־לֹהִים תּוֹלַעַת בַּעֲלוֹת הַשַּׁחַר" (יונה ד, ז). ואילו בלשון השירה והנבואה שחר נזכר גם לצד פעלים אחרים: "אָז יִבָּקַע כַּשַּׁחַר אוֹרֶךָ" (ישעיהו נח, ח); "מִי זֹאת הַנִּשְׁקָפָה כְּמוֹ שָׁחַר" (שיר השירים ו, י). ומה בין המילה...
Wed May 27, 2020 13:03
Aims Late gadolinium enhancement (LGE) visualizes scar tissue after myocardial infarction. However, in clinically used LGE sequences, subendocardial infarcts can be missed due to low contrast between blood pool and subendocardium. The purpose of his study was to compare scar visibility in a novel 3-dimensional (3D) single breath-hold inversion recovery sequence with fixed, short inversion time (TI = 100 milliseconds) (short LGE) and standard 3D LGE imaging with individually adjusted TI (LGE)....
Tue May 26, 2020 03:00
The paramedian forehead flap is a major workhorse for reconstruction of medium to large-sized nasal defects. The tissue bridge that results from the vascular pedicle results in significant cosmetic deformity, with associated social and occupational costs to the patient. This prospective cross sectional study sought to assess efficacy and safety of takedown of the flap pedicle at one week using indocyanine green (IGC) angiography to assist in determining neovascularization of the flap. This study...
Wed May 27, 2020 03:00
Persistent neuropathic pain severely impacts physical functioning and quality of life (QoL). However, optimal surgical management of persistent neuropathic pain remains unclear. Extensive neurolysis with subsequent free muscle flap coverage, a new surgical procedure for neuropathic pain in the upper extremity, can be performed as final option to establish pain reduction.
Wed May 27, 2020 03:00
A drooping oral commissure shows an appearance of ageing and sadness. To improve it with less complications has become a rising aesthetic concern in Asians.
Wed May 27, 2020 03:00
Immunoglobulin replacement therapy (IgG) is the mainstay of treatment in many primary immunodeficiency diseases (PIDD), including common variable immunodeficiency, hypogammaglobulinemia, and antibody deficiency. Compared to intravenous administration, subcutaneous delivery is becoming the preferred route of delivery for patients due to its flexibility and mitigation of side effects1. The subcutaneous route is administered without the need for intravenous access and there‘s a decreased risk for systemic...
Wed May 27, 2020 03:00
Purpose Mantle-cell lymphoma (MCL) is an incurable mature B-cell neoplasm with high initial response rates followed almost invariably by relapse. Prognosis for patients following relapse is poor, and treatment choices are limited. We evaluated the efficacy and safety of zanubrutinib, an investigational selective Bruton's tyrosine kinase (BTK) inhibitor. Patients and Methods Patients with relapsed/refractory MCL were enrolled in this ongoing phase 2, single-arm, open-label study and treated with oral...
Wed May 27, 2020 15:40
Presentation of Case. Dr. Kathy M. Tran: A 74-year-old man with mantle-cell lymphoma was admitted to this hospital during the coronavirus disease 2019 (Covid-19) pandemic because of acute respiratory failure. One day before this admission, productive cough and dyspnea developed. The next day, when…
Wed May 27, 2020 03:00
Egg-laying behavior in Caenorhabditis elegans is a well-known model for investigating fundamental cellular processes. In egg-laying, muscle contraction is the relaxation of the vulval muscle to extrude eggs from the vulva. Unlike skeletal muscle, vulval muscle lacks visible striations of the sarcomere. Therefore, vulval muscle must counteract the mechanical stress, caused by egg extrusion and body movement, from inducing cell-shape distortion by maintaining its cytoskeletal integrity. However, the...
Wed May 27, 2020 23:56
Researchers have extensively studied several neighboring groups of western chimpanzees and their findings reveal that females and even the entire group may play a more important role in between-group competition than previously thought. They found that even though adult males seem important in territory increase, territory maintenance and competitive advantage over neighbors act through the entire group in this population of chimpanzees in the Taï National Park.
Wed May 27, 2020 19:33
An international team of scientists has examined how metabolic constraints govern the diving performance of air-breathing aquatic species, all of which have evolved to maximise the amount of time they can spend underwater.
Wed May 27, 2020 03:35
The interaction between 'transfer RNAs' and the enzymes that help them in protein synthesis has always been the key area of interest for understanding the evolution of the genetic code. Now, a team of scientists reports that a subunit of 'alanyl-tRNA synthetase' enzyme of the primitive microorganism Nanoarchaeum equitans can mimic the super-primitive tRNA 'aminoacylation' independent of the presence of a special 'G3:U70' base pair, a property previously unseen in primitive organisms.
Tue May 26, 2020 23:11
Despite conventional understanding that three Kai proteins are required for the circadian oscillation of cyanobacteria, scientists discovered that even when one of them is destroyed, the oscillation is not completely abolished but instead damped. Further, they found that the damped rhythms resonate with external cycles of approximately 24 hours, which indicates that the natural frequency of the damped oscillation is similar to a circadian clock.
Tue May 26, 2020 20:46
How could the tiny parts of the ear adapt independently to the diverse functional and environmental regimes encountered in mammals? A group of researchers proposed a new explanation for this puzzle. They suggest that the incorporation of the bones of the primary jaw joint into the ear has considerably increased the genetic, regulatory, and developmental complexity of the mammalian ear.
Wed May 27, 2020 17:50
One of the most promising theories for the evolution of human speech has finally received support from chimpanzee communication.
Wed May 27, 2020 03:35
Abstract Follower loads are used to simulate physiological compressive loads on the human spine. These compressive loads represent the load-carrying capacity of the human cervical spine and play an important role in maintaining its stability. However, under different follower loads the biomechanical response of the cervical spine is unknown. Therefore, the aim of this study was to determine the effect of follower load on the biomechanics of the cervical spine. A three-dimensional...
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Analytical ChemistryDOI: 10.1021/acs.analchem.9b05759
Wed May 27, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01676
Wed May 27, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01073
Wed May 27, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00275
Wed May 27, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01507
Wed May 27, 2020 07:00
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