Abstract Because of the COVID‐19 emergency, on March 9, 2020 Italy went in lock‐down imposing the closure of non‐urgent outpatient clinics devoted to care of chronic, severe, inflammatory skin diseases that require periodic follow‐up. In this emergency situation, due to the lack of a teledermatology platform and in order not to leave our vulnerable high‐need patients without proper follow‐up, we started a teledermatologic service in smartworking using phone calls and emails. The total number of...
Tue May 26, 2020 17:34
Related ArticlesFruit and Vegetable Purchases and Consumption among WIC Participants after the 2009 WIC Food Package Revision: A Systematic Review. Adv Nutr. 2020 May 26;: Authors: Zhang Q, Alsuliman MA, Wright M, Wang Y, Cheng X Abstract To promote fruit and vegetable (FV) intake among participants, the USDA Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) implemented a comprehensive food package revision in 2009. However,...
Wed May 27, 2020 14:15
Combination therapy of interferon and ribavirin has traditionally been used to eradicate hepatitis C virus. The sustained virologic response achieved with interferon-related therapy is persistent, and late rel...
Wed May 27, 2020 03:00
Although gastrointestinal involvement is the most common site for extra-genital endometriosis, deep infiltrative endometriosis, which affects the mucosal layer, is very rare.
Tue May 26, 2020 03:00
Background Oxidative-stress (OS) was causal in the development of cell dysfunction and insulin resistance. Streptozotocin (STZ) was an alkylation agent that increased reactive oxygen species (ROS) levels. Here we aimed to explore the oxidative-stress and related RNAs in the liver of STZ-induced diabetic mice. Methods RNA-sequencing was performed using liver tissues from STZ induced diabetic mice and controls. Pathway...
Wed May 27, 2020 03:00
Background Especially on commodities crops like soybean, maize, cotton, coffee and others, high yields are reached mainly by the intensive use of pesticides and fertilizers. The biological management of crops is a relatively recent concept, and its application has increased expectations about a more sustainable agriculture. The use of fungi as plant bioinoculants has proven to be a useful alternative in this process, and research is deepening on genera and species with some already known potential....
Wed May 27, 2020 03:00
Background The peste-des-petits-ruminants virus (PPRV) is a highly devastating virus of small ruminants in many parts of the world, including the Kingdome of Saudi Arabia. Therefore, our objectives were (1) to conduct a molecular prevalence study of PPRV in sheep and goat across the KSA and (2) to isolate and identify currently circulating PPRV lineages. Swabs and tissue specimens were collected from 97 herds suspected to be infected with PPRV across the Kingdome of Saudi Arabia...
Wed May 27, 2020 03:00
Seamounts are important deep ocean entities that serve as reservoirs for varied types of habitats and fauna. During the Chinese cruises in the northwestern Pacific seamount areas, a new starfish species of order Brisingida, Astrolirus patricki, was found at 1,458–2,125 m depth. All specimens of the new species were observed in situ attaching on hexactinellid sponges, suggesting a possible close relationship between the two taxa. A. patricki sp. nov. is the second known species of the genus, characterized...
Wed May 27, 2020 03:00
Background Serious haze episodes have been a seasonal event in Chiang Mai province for more than a decade. In 2008, local government agencies introduced comprehensive measures to control haze and limit its impacts on public health. This study assessed the acute effects of ambient air pollutants on all-cause mortality before and after the introduction of those haze control measures. Methods We obtained daily mortality...
Wed May 27, 2020 03:00
Background Burkholderia pseudomallei causes melioidosis, a serious illness that can be fatal if untreated or misdiagnosed. Culture from clinical specimens remains the gold standard but has low diagnostic sensitivity. Method In this study, we developed a rapid, sensitive and specific insulated isothermal Polymerase Chain Reaction (iiPCR) targeting bimA gene (Burkholderia Intracellular Motility A; BPSS1492) for the identification...
Wed May 27, 2020 03:00
Background Brasilonema is a cyanobacterial genus found on the surface of mineral substrates and plants such as bromeliads, orchids and eucalyptus. B. octagenarum stands out among cyanobacteria due to causing damage to the leaves of its host in an interaction not yet observed in other cyanobacteria. Previous studies revealed that B. octagenaum UFV-E1 is capable of leading eucalyptus leaves to suffer internal tissue damage and necrosis by unknown mechanisms. This work aimed to investigate...
Wed May 27, 2020 03:00
Objectives To demonstrate the screening value of echocardiography for portopulmonary hypertension (POPH) in liver transplant candidates. Design Systematic review and meta-analysis. Background POPH is a complication of end-stage liver disease that adversely affects the outcome of orthotopic liver transplant. There are no specific symptoms in the early stage...
Wed May 27, 2020 03:00
The resources available for conserving biodiversity are limited, and so protected areas need to be established in places that will achieve objectives for minimal cost. Two of the main algorithms for solving systematic conservation planning problems are Simulated Annealing (SA) and exact integer linear programing (EILP) solvers. Using a case study in BC, Canada, we compare the cost-effectiveness and processing times of SA used in Marxan versus EILP using both commercial and open-source algorithms....
Wed May 27, 2020 03:00
The surface area (SA) of organs and cells may vary with temperature, which changes the SA exchange limitation on metabolic flows as well as the influence of temperature on metabolic scaling. The effect of SA change can intensify (when the effect is the same as that of temperature) or compensate for (when the effect is the opposite of that of temperature) the negative effects of temperature on metabolic scaling, which can result in multiple patterns of metabolic scaling with temperature among species....
Wed May 27, 2020 03:00
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/05/27PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed May 27, 2020 14:08
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/05/27PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed May 27, 2020 13:07
Related ArticlesUse and awareness of and willingness to self-test for HIV: an analysis of cross-sectional population-based surveys in Malawi and Zimbabwe. BMC Public Health. 2020 May 25;20(1):779 Authors: Johnson C, Neuman M, MacPherson P, Choko A, Quinn C, Wong VJ, Hatzold K, Nyrienda R, Ncube G, Baggaley R, Terris-Prestholt F, Corbett EL Abstract BACKGROUND: Many southern African countries are nearing the global goal of diagnosing 90% of people with...
Wed May 27, 2020 14:06
Related ArticlesCorrection to: Informal payments for inpatient health care in post-health transformation plan period: evidence from Iran. BMC Public Health. 2020 May 25;20(1):781 Authors: Doshmangir L, Sajadi HS, Ghiasipour M, Aboutorabi A, Gordeev VS Abstract An amendment to this paper has been published and can be accessed via the original article.PMID: 32450836 [PubMed - in process]
Wed May 27, 2020 14:06
Related ArticlesEmerging pesticides responsible for suicide in rural Sri Lanka following the 2008-2014 pesticide bans. BMC Public Health. 2020 May 25;20(1):780 Authors: Weerasinghe M, Pearson M, Konradsen F, Agampodi S, Sumith JA, Jayamanne S, Senanayake SMHMK, Rajapaksha S, Eddleston M Abstract BACKGROUND: Sri Lanka has reduced its overall suicide rate by 70% over the last two decades through means restriction, through a series of government regulations...
Wed May 27, 2020 14:06
New England Journal of Medicine, Ahead of Print.
Tue May 26, 2020 07:01
New England Journal of Medicine, Ahead of Print.
Tue May 26, 2020 07:00
Related ArticlesLong-term surgical outcomes of patients with delayed diagnosis of spinal dural arteriovenous fistula. J Clin Neurosci. 2020 May 22;: Authors: Zhang L, Qiao G, Shang A, Yu X Abstract Spinal dural arteriovenous fistula (dAVF) is an extremely rare vascular entity that is usually misdiagnosed. We sought to determine the long-term clinical outcomes of patients undergoing microsurgical treatment for delayed diagnosis of spinal dAVF. This retrospective...
Wed May 27, 2020 14:00
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a type of invasive malignancy and the seventh most common cancer in the worldwide. Cancer stem cells (CSCs) are self‐renewal cells in tumors and can produce heterogeneous tumor cells, which play an important role in the development of HNSCC. In our research, we aimed to identify genes related to the CSCs characteristics in HNSCC. Methods Messenger RNA (mRNA) expression‐based stiffness index (mRNAsi) can be used as a quantitative...
Wed May 27, 2020 12:46
Related ArticlesZerumbone Promotes Cytotoxicity in Human Malignant Glioblastoma Cells through Reactive Oxygen Species (ROS) Generation. Oxid Med Cell Longev. 2020;2020:3237983 Authors: Jalili-Nik M, Sadeghi MM, Mohtashami E, Mollazadeh H, Afshari AR, Sahebkar A Abstract Glioblastoma multiforme (GBM) is the most hostile tumor in the central nervous system. Unfortunately, the prognosis of GBM patients is poor following surgical interventions, chemotherapy,...
Wed May 27, 2020 14:54
Related ArticlesStyrene Oxide Caused Cell Cycle Arrest and Abolished Myogenic Differentiation of C2C12 Myoblasts. J Toxicol. 2020;2020:1807126 Authors: Surinlert P, Kongthong N, Watthanard M, Sae-Lao T, Sookbangnop P, Pholpramool C, Tipbunjong C Abstract Contaminations of chemicals in foods and drinks are raising public concerns. Among these, styrene, a monomer for plastic production, receives increasing interest due to its ability to leach from...
Wed May 27, 2020 14:54
Related ArticlesComprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells. Turk J Pharm Sci. 2019 Jun;16(2):119-131 Authors: Akalin Çiftçi G, Sever B, Altintop MD Abstract Objectives: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to...
Wed May 27, 2020 14:54
Related ArticlesAn acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells. Bioorg Chem. 2020 May 18;100:103935 Authors: Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Gutiérrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Chávez-Báez I, Pulgar R, Urra FA, Varela-Ramírez A, Araya-Maturana R Abstract Since...
Wed May 27, 2020 14:54
Related Articles3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages. Environ Pollut. 2020 May 07;265(Pt B):114697 Authors: Liu N, Yang Y, Chen J, Jia H, Zhang Y, Jiang D, Wu G, Wu Z Abstract 3-Acetyldeoxynivalenol (3-Ac-DON), the acetylated derivative of deoxynivalenol (DON), has been reported to be coexisted with DON in various cereal grains. Ingestion of grain-based food...
Wed May 27, 2020 14:54
Related ArticlesEprinomectin, a novel avermectin macrocylic lactone is cytotoxic to PC3 metastatic prostate cancer cells via inducing apoptosis. Toxicol Appl Pharmacol. 2020 May 23;:115071 Authors: Samy ALPA, Bakthavachalam V, Vudutha M, Vinjamuri S, Chinnapaka S, Munirathinam G Abstract Prostate Cancer (PCa) is the second most common cancer among men in United States after skin cancer. Conventional chemotherapeutic drugs available for PCa treatment...
Wed May 27, 2020 14:54
Related ArticlesA biomimetic nanozyme/camptothecin hybrid system for synergistically enhanced radiotherapy. J Mater Chem B. 2020 May 26;: Authors: Zhu D, Lyu M, Jiang W, Suo M, Huang Q, Li K Abstract Although radiotherapy (RT) has been an effective therapeutic regimen against most solid tumors, its effect is limited by the hypoxic tumor microenvironment and radio-tolerance of tumor cells to a large extent. Here we have designed a biomimetic nanozyme/camptothecin...
Wed May 27, 2020 14:54
Related ArticlesDesign, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors. Arch Pharm (Weinheim). 2020 May 26;:e2000060 Authors: El-Hamamsy MH, Sharafeldin NA, El-Moselhy TF, Tawfik HO Abstract Lung, colorectal, and breast cancers are the top three types of cancer by incidence and are responsible for one-third of the cancer incidence and mortality. A series of 18 3,4-dihydropyrimidine analogues...
Wed May 27, 2020 13:55
Related ArticlesDihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition. Biosci Rep. 2020 May 26;: Authors: Yi R, Wang H, Deng C, Wang X, Yao L, Niu W, Fei M, Zhaba W Abstract It has been demonstrated from previous studies about the killing effect of dihydroartemisinin(DHA) on glioblastoma, which involves multiple aspects: cytotoxicity, cell cycle arrest and invasion inhibition. DHA has the advantages of low cytotoxicity...
Wed May 27, 2020 13:55
Related ArticlesMALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-κB activation. J Cell Mol Med. 2020 May 25;: Authors: Liu X, Yue C, Shi L, Liu G, Cao Q, Shan Q, Wang Y, Chen X, Li H, Wang J, Gao S, Niu M, Yu R Abstract Glioblastoma multiforme (GBM) is the most common malignant tumour in the adult brain and hard to treat. Nuclear factor κB (NF-κB) signalling has a crucial role in the tumorigenesis...
Wed May 27, 2020 13:55
Related ArticlesAvasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest. Acta Pharmacol Sin. 2020 May 25;: Authors: Liu JY, Fu WQ, Zheng XJ, Li W, Ren LW, Wang JH, Yang C, Du GH Abstract Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, but there is no effective drug available for GBM. Avasimibe is a potent inhibitor of acyl-coenzyme A: cholesterol acyltransferase-1...
Wed May 27, 2020 13:55
Related ArticlesCordycepin inhibits pancreatic cancer cell growth in vitro and in vivo via targeting FGFR2 and blocking ERK signaling. Chin J Nat Med. 2020 May;18(5):345-355 Authors: Li XY, Tao H, Jin C, DU ZY, Liao WF, Tang QJ, Ding K Abstract Cordycepin (3'-deoxyadenosine) from Cordyceps militaris has been reported to have anti-tumor effects. However, the molecular target and mechanism underlying cordycepin impeding pancreatic cancer cell growth...
Wed May 27, 2020 13:55
Related ArticlesMelatonin Improves In Vitro Development of Vitrified-Warmed Mouse Germinal Vesicle Oocytes Potentially via Modulation of Spindle Assembly Checkpoint-Related Genes. Cells. 2019 08 30;8(9): Authors: Wu Z, Pan B, Qazi IH, Yang H, Guo S, Yang J, Zhang Y, Zeng C, Zhang M, Han H, Meng Q, Zhou G Abstract The present study aimed to investigate the effect of melatonin (MT) supplementation on in vitro maturation of vitrified mouse germinal vesicle...
Wed May 27, 2020 13:55
Related ArticlesCircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression. Cancer Lett. 2019 09 28;460:139-151 Authors: Zheng F, Wang M, Li Y, Huang C, Tao D, Xie F, Zhang H, Sun J, Zhang C, Gu C, Wang Z, Jiang G Abstract Accumulating evidences suggest that circular RNAs play vital roles in human cancers. Previously, we found that circHIPK3 suppressed invasion of bladder cancer cells via...
Wed May 27, 2020 13:55
Related ArticlesMicroRNA-128 confers protection against cardiac microvascular endothelial cell injury in coronary heart disease via negative regulation of IRS1. J Cell Physiol. 2019 08;234(8):13452-13463 Authors: Yan P, Sun C, Ma J, Jin Z, Guo R, Yang B Abstract OBJECTIVE: Cardiac microvascular endothelial cells (CMECs) play a critical role in the physiological regulation of coronary blood flow and its dysfunction is associated with myocardium ischemic...
Wed May 27, 2020 13:55
Related ArticlesRole of SNHG7-miR-653-5p-STAT2 feedback loop in regulating neuroblastoma progression. J Cell Physiol. 2019 08;234(8):13403-13412 Authors: Chi R, Chen X, Liu M, Zhang H, Li F, Fan X, Wang W, Lu H Abstract Long noncoding RNAs (lncRNAs) are reported to be involved in the pathology of numerous cancers, including neuroblastoma (NB). lncRNA SNHG7 has been recognized as a carcinogen in several cancers, but its role in NB progression remains...
Wed May 27, 2020 13:55
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