Related ArticlesHearing loss and employment: a systematic review of the association between hearing loss and employment among adults. J Laryngol Otol. 2020 May 29;:1-11 Authors: Shan A, Ting JS, Price C, Goman AM, Willink A, Reed NS, Nieman CL Abstract BACKGROUND: Hearing loss affects over 1.3 billion individuals worldwide, with the greatest burden among adults. Little is known regarding the association between adult-onset hearing loss and employment....
Related ArticlesSemon Lecture: 'From the Felix to the helix, and from the cradle to the grave - Semon's contribution to thyroid surgery', Royal Society of Medicine, 1 November 2019, London, UK. J Laryngol Otol. 2020 May 29;:1-6 Authors: Watkinson JC Abstract Mr President, Mr President Elect, Fellows and Members, Ladies and Gentleman, it is a pleasure to address the Section of Laryngology this morning and deliver the 94th Semon Lecture. I would like...
Use of Steroid-Eluting Stents after Endoscopic Repair of Choanal Atresia: A Case Series with Review.
Related ArticlesUse of Steroid-Eluting Stents after Endoscopic Repair of Choanal Atresia: A Case Series with Review. Ann Otol Rhinol Laryngol. 2020 May 29;:3489420928374 Authors: Wilcox LJ, Smith MM, de Alarcon A, Epperson M, Born H, Hart CK Abstract OBJECTIVE(S): To describe a single institution's experience with the use of steroid-eluting stents after endoscopic transnasal repair of choanal atresia. METHODS: A case series with review...
Related ArticlesFactors Associated with Failure of Botulinum Toxin Injection in Adductor Spasmodic Dysphonia. Ann Otol Rhinol Laryngol. 2020 May 29;:3489420928373 Authors: Zhao K, Guillaud M, Hu A Abstract OBJECTIVE: Electromyography (EMG) Guided botulinum toxin (BTX) injection is considered first-line treatment for adductor spasmodic dysphonia (SD). Failure rate can range between 6% and 29%. Study objective was to determine which factors were associated...
Related ArticlesSurgical Intervention for Laryngomalacia: Age-Related Differences in Postoperative Sequelae. Ann Otol Rhinol Laryngol. 2020 May 29;:3489420922862 Authors: Patel VA, Adkins D, Ramadan J, Williamson A, Carr MM Abstract OBJECTIVE: Identify risk factors and determine perioperative morbidity of children undergoing surgery for laryngomalacia (LM). METHODS: A retrospective analysis of the multi-institutional American College of...
Related ArticlesDecreased numbers of metachromatic cells in nasal swabs in Japanese cedar pollinosis following sublingual immunotherapy. Immun Inflamm Dis. 2020 May 28;: Authors: Otsuka K, Otsuka H, Matsune S, Okubo K Abstract BACKGROUND AND OBJECTIVE: Nasal symptoms were reduced following allergen-specific sublingual immunotherapy (SLIT) for allergic rhinitis. The mechanisms underlying the effectiveness of SLIT for Japanese cedar pollinosis are...
Related ArticlesPlac8-mediated autophagy regulates nasopharyngeal carcinoma cell function via AKT/mTOR pathway. J Cell Mol Med. 2020 May 29;: Authors: Huang ML, Qi CL, Zou Y, Yang R, Jiang Y, Sheng JF, Kong YG, Tao ZZ, Chen SM Abstract To explore the relationship between autophagy and cell function, we investigated how PLAC8-mediated autophagy influences proliferation, apoptosis and epithelial-mesenchymal transition (EMT) in NPC. Colony formation...
Related ArticlesThe role of head and neck cancer advocacy organizations during the COVID-19 pandemic. Head Neck. 2020 May 29;: Authors: Yan F, Rauscher E, Hollinger A, Caputo MA, Ready J, Fakhry C, Nathan CO, Leonardis C, Yearout D, Tsue TT, Day TA, Moore MG Abstract The COVID-19 pandemic has had a significant impact on many aspects of head and neck cancer (HNC) care. The uncertainty and stress resulting from these changes has led many patients and...
Related ArticlesDistinct immune evasion in APOBEC-enriched, HPV-negative HNSCC. Int J Cancer. 2020 May 29;: Authors: Messerschmidt C, Obermayer B, Klinghammer K, Ochsenreither S, Treue D, Stenzinger A, Glimm H, Fröhling S, Kindler T, Brandts CH, Schulze-Osthoff K, Weichert W, Tinhofer I, Klauschen F, Keilholz U, Beule D, Rieke DT Abstract Immune checkpoint inhibition leads to response in some patients with head and neck squamous cell carcinoma (HNSCC)....
Related ArticlesMicro-metastasis and isolated tumour cells: the span between elective neck dissection versus neck observation in early oral cancer. Eur Arch Otorhinolaryngol. 2020 May 28;: Authors: Subash A, Singh A, Sinha P Abstract Early oral squamous cell carcinoma (SCC) has a propensity for lymph-node metastasis. To address or not to address the neck electively during the ablative surgery has been an ongoing debate. In recent years, some practice-changing...
Related ArticlesA detection dog for obstructive sleep apnea: could it work in diagnostics? Sleep Breath. 2020 May 29;: Authors: Vaarno J, Myller J, Bachour A, Koskinen H, Bäck L, Klockars T, Koskinen A Abstract PURPOSE: We have previously demonstrated that dogs can be trained to distinguish the urine of patients with obstructive sleep apnea (OSA) from that of healthy controls based on olfaction. Encouraged by these promising results, we wanted to...
Related ArticlesPostintubation Dysphagia During COVID-19 Outbreak-Contemporary Review. Dysphagia. 2020 May 28;: Authors: Frajkova Z, Tedla M, Tedlova E, Suchankova M, Geneid A Abstract The COVID-19 is a global pandemic. Its rapid dissemination and serious course require a novel approach to healthcare practices. Severe disease progression is often associated with the development of the Acute Respiratory Distress Syndrome and may require some form...
Related Articles[Organ preservation in advanced laryngeal/hypopharyngeal carcinoma: lessons from the DeLOS-II trial]. HNO. 2020 May 28;: Authors: Dietz A, Wichmann G, Kuhnt T, Wiegand S Abstract Patients with locoregionally advanced laryngeal and hypopharyngeal squamous cell carcinomas (LHSCC) comprise two broad groups: those who are candidates for functional larynx preservation (LP) with avoidance of ablative surgery and those who are not. Currently,...
Related ArticlesThe round window sign: a sensitive sign to detect perilymphatic fistulae on delayed postcontrast 3D-FLAIR sequence. Eur Radiol. 2020 May 28;: Authors: Dubrulle F, Chaton V, Risoud M, Farah H, Charley Q, Vincent C Abstract OBJECTIVES: The aim of this study is to assess the diagnostic performance of a new MR sign, named the round window sign (RWS), to diagnose perilymphatic fistula (PLF) in a population of patients with chronic cochleo-vestibular...
Related ArticlesLong non‑coding RNA‑based risk scoring system predicts prognosis of alcohol‑related hepatocellular carcinoma. Mol Med Rep. 2020 May 22;: Authors: Luo Y, Ye J, Wei J, Zhang J, Li Y Abstract Increasing evidence suggests that long non-coding RNAs (lncRNAs) serve a crucial role in predicting prognosis for hepatocellular carcinoma (HCC). However, prognostic performance may not be the same for alcohol‑related HCC. The aim of the present...
Related ArticlesPan‑cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS‑CoV‑2 infection leading to COVID-19. Int J Oncol. 2020 May 26;: Authors: Katopodis P, Anikin V, Randeva HS, Spandidos DA, Chatha K, Kyrou I, Karteris E Abstract Severe acute respiratory syndrome (SARS) coronavirus‑2 (SARS‑CoV2) is the cause of a new disease (COVID‑19) which has evolved into a pandemic during the first half of 2020. Older...
Related ArticlesAnkara bombing: distribution of injury patterns with radiological imaging. Pol J Radiol. 2020;85:e90-e96 Authors: Parlak S, Beşler MS Abstract Purpose: To describe and explain the blast injuries and imaging findings in the Ankara terrorist explosion that took place on October 10, 2015. Material and methods: A total of 77 patients who underwent radiologic imaging were classified as primary, secondary, tertiary, and quaternary,...
Related ArticlescircRNA-miRNA-mRNA regulatory network in human lung cancer: an update. Cancer Cell Int. 2020;20:173 Authors: Liang ZZ, Guo C, Zou MM, Meng P, Zhang TT Abstract Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been studied, probed and applied into several diseases, such as cardiovascular diseases, systemic lupus erythematosus, leukemia, pulmonary tuberculosis, and cancer especially. Recently, mounting evidence...
Related ArticlesClinicopathological and prognostic significance of nestin expression in patients with breast cancer: a systematic review and meta-analysis. Cancer Cell Int. 2020;20:169 Authors: Zhang X, Xing C, Guan W, Chen L, Guo K, Yu A, Xie K Abstract Background: Nestin has been revealed to promote tumorigenesis, progression, metastasis, and angiogenesis of breast cancer. Although the prognostic and clinicopathological impact of nestin expression...
Related ArticlesPrognostic role of alternative splicing events in head and neck squamous cell carcinoma. Cancer Cell Int. 2020;20:168 Authors: Ding Y, Feng G, Yang M Abstract Background: Aberrant alternative splicing (AS) is implicated in biological processes of cancer. This study aims to reveal prognostic AS events and signatures that may serve as prognostic predictors for head and neck squamous cell carcinoma (HNSCC). Methods: Prognostic...
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Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveBI6727, an ATP-competitive PLK1 inhibitor, has been shown to cause cell death in multi-tumors. This study aimed to investigate the anti-tumor effect and potential molecular mechanism of BI6727 in human Burkitt lymphoma (BL) cell lines.MethodsWe assessed polo-like kinase 1 (PLK1) expression in BL patient tissues and cells, also investigated the cytotoxic effect using CCK8 assay and flow cytometry. In addition, western...
Fri May 29, 2020 12:43
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveReliable methods to prevent chyle leakage after esophagectomy are needed. This retrospective study was performed to evaluate the correlation between low-fat nutrition and the incidence of chyle leakage after esophagectomy.MethodsThis multicenter retrospective case–control study involved patients who underwent Ivor Lewis esophagectomy from December 2012 to August 2017. Tube feeding was started on postoperative day 1...
Fri May 29, 2020 12:38
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectivePost-extubation stridor and hoarseness are important clinical manifestations that indicate laryngeal edema due to intubation. In previous studies the incidence of post-extubation stridor and hoarseness ranged from 1.5% to 26.3% in postoperative patients and patients in the intensive care unit. Female sex and prolonged intubation are reportedly risk factors for post-extubation stridor. However, the risk factors for post-extubation...
Fri May 29, 2020 12:31
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo investigate the application of mind mapping-based health education in extended care for children with caries.MethodsThis was a prospective study of 159 eligible children with caries. Participants were randomly assigned to an observation group and a control group, and received extended health education and guidance. Patients in the observation group received health education with mind mapping. In the third month after...
Fri May 29, 2020 12:11
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study aimed to describe drug utilisation in a large Chinese neonatal unit and to compare the findings with those from other countries.MethodsData were collected from electronic medical records. Prescription drugs were defined as the number of unique medication names for each patient. Medicine doses were defined as the total number of doses of all medicines administered. Information was collected regarding drugs...
Fri May 29, 2020 12:02
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectivePrevious studies reported the effect of dexmedetomidine on intrathecal anesthesia. In this review, we explored the impact of dexmedetomidine as an adjunct for lumbar anesthesia in patients undergoing cesarean section.MethodsTwo authors searched eligible random controlled trials in electronic databases, including PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, the Chinese BioMedical...
Fri May 29, 2020 11:56
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveWe aimed to understand the reasons behind outpatient loss to follow-up and the views of Chinese patients with depression regarding disease diagnosis and antidepressant therapy.MethodsConsecutive outpatients with newly diagnosed depressive disorder between September 2012 and August 2013 at the Shanghai First People’s Hospital (a tertiary hospital) were categorized into follow-up and lost-to-follow-up groups. We collected...
Fri May 29, 2020 11:17
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Fatal asthma is a rare and potentially fatal disease. This disease requires suitable treatment to achieve rehabilitation, especially when accompanied by other complications, such as a silent chest and severe bronchial spasm. A 36-year-old man presented with a 10-year history of asthma that broke out into persistent asthma attacks and cardiac arrest, and was accompanied by a silent chest for 18 hours. He recovered and was discharged...
Fri May 29, 2020 11:13
Journal of International Medical Research, Volume 48, Issue 5, May 2020. Pulmonary cement embolism (PCE) is one of several complications of percutaneous vertebroplasty and kyphoplasty. Generally, PCE can be easily diagnosed based on typical chest radiograph findings such as single or multiple radiographically dense opacities with a tubular or branch shape in the lung field along with a recent history of percutaneous vertebroplasty or kyphoplasty. These findings can be alarming and may be encountered...
Fri May 29, 2020 11:08
Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThis study was performed to compare the clinical outcomes of traditional three-dimensional (3D) printing technology and 3D printing mirror model technology in the treatment of isolated acetabular fractures.MethodsProspectively maintained databases were reviewed to retrospectively compare patients with an isolated acetabular fracture who were treated with traditional 3D printing technology (Group T) or 3D printing mirror...
Fri May 29, 2020 11:04
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Related ArticleslncRNA-SOX2OT promotes hepatocellular carcinoma invasion and metastasis through miR-122-5p-mediated activation of PKM2. Oncogenesis. 2020 May 28;9(5):54 Authors: Liang Y, Zhang D, Zheng T, Yang G, Wang J, Meng F, Liu Y, Zhang G, Zhang L, Han J, Hui P, Chen Z, Liu Y, Wang M, Jiang H, Liu L Abstract Tumor cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect, but the involvement of...
Related ArticlesSurgical outcomes of transmastoid facial nerve decompression: Preliminary data from a Malaysian tertiary hospital from 2013-2018. Med J Malaysia. 2020 May;75(3):281-285 Authors: Siang PG, Ying XT, Dayang Suhana AM, Ing PT Abstract INTRODUCTIONS: Facial nerve palsy (FNP) occurs in 7-10% of temporal bone fractures. The aim of this study was to review the surgical outcome of nine patients with severe to complete traumatic facial nerve...
Related ArticlesNeck Imaging Reporting and Data System: What Does Radiologist Want to Know? J Comput Assist Tomogr. 2020 May 27;: Authors: Abdel Razek AAK, Abdelaziz TT Abstract The aim of this work was to review Neck Imaging Reporting and Data System (NI-RADS) that was designed for reporting and surveillance of head and neck cancer after therapy and their subsequent management. The categories of NI-RADS can be designated as belonging in 1 of the...
Related ArticlesPhysical and Vestibular Physical Therapy Referrals in People With Alzheimer Disease. Alzheimer Dis Assoc Disord. 2020 May 27;: Authors: Gandhi P, Klatt BN, Agrawal Y Abstract People with Alzheimer disease (AD) are at increased risk of falls and disproportionately burdened with vestibular impairment compared with healthy older adults. Although physical therapy (PT) and vestibular physical therapy (VPT) are effective rehabilitation...
Related ArticlesPositive Predictive Value of Neck Imaging Reporting and Data System Categories 3 and 4 Posttreatment FDG-PET/CT in Head and Neck Squamous Cell Carcinoma. AJNR Am J Neuroradiol. 2020 May 28;: Authors: Wangaryattawanich P, Branstetter BF, Ly JD, Duvvuri U, Heron DE, Rath TJ Abstract BACKGROUND AND PURPOSE: The Neck Imaging Reporting and Data System is a standardized reporting system intended to risk stratify patients treated for head...
Related ArticlesNew Imaging Findings of Incomplete Partition Type III Inner Ear Malformation and Literature Review. AJNR Am J Neuroradiol. 2020 May 28;: Authors: Hong R, Du Q, Pan Y Abstract Incomplete partition type III, also referred to as X-linked deafness, is a rare genetic inner ear malformation. Its characteristic CT findings, including bulbous dilation of the internal auditory canal and absence of the modiolus with the interscalar septa present,...
Related ArticlesPRAS40 phosphorylation correlates with insulin-like growth factor-1 receptor-induced resistance to epidermal growth factor receptor inhibition in head and neck cancer cells. Mol Cancer Res. 2020 May 28;: Authors: Dougherty MI, Lehman CE, Spencer A, Mendez RE, David AP, Taniguchi LE, Wulfkuhle J, Petricoin EF, Gioeli D, Jameson MJ Abstract Epidermal growth factor receptor (EGFR) inhibitors have shown poor efficacy in head and neck...
Related ArticlesStage pN3a in oral cancer: A redundant entity? Oral Oncol. 2020 May 25;:104815 Authors: Subramaniam N, Clark JR, Goldstein D, de Almeida J, Ali Abdalaty AH, Balasubramanian D, Thankappan K, Iyer S, Batstone M, Gopal Iyer N, Smee RI, Chandrasekhar NH, Pillai V, Shetty V, Rangappa V, Veness M, Hubert Low TH PMID: 32467072 [PubMed - as supplied by publisher]
Related ArticlesPractice Patterns and Barriers in Botulinum Toxin Injection for the Treatment of Voice Disorders. J Voice. 2020 May 26;: Authors: McGarey PO, Simpson CB, Daniero JJ Abstract Laryngeal botulinum toxin injection is an important treatment modality for spasmodic dysphonia and other laryngeal disorders. We sought to compare usage patterns of laryngeal botulinum toxin injections for voice disorders and to identify and quantify inefficiencies...
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