Related ArticlesThe incidence and effect of tethered cord release for tethered cord syndrome in patients with myelomeningocele: a population-based study. J Neurosurg Pediatr. 2020 May 29;:1-6 Authors: Borgstedt-Bakke JH, Wichmann TO, Gudmundsdottir G, Rasmussen MM Abstract OBJECTIVE: The goal of this study was to establish an incidence and assess the effect of tethered cord release for tethered cord syndrome in patients with myelomeningocele. ...
Related ArticlesPediatric vestibular schwannomas: case series and a systematic review with meta-analysis. J Neurosurg Pediatr. 2020 May 29;:1-9 Authors: Malina GEK, Heiferman DM, Riedy LN, Szujewski CC, Rezaii EG, Leonetti JP, Anderson DE Abstract OBJECTIVE: Sporadic unilateral vestibular schwannomas are rare in the pediatric population. Little has been reported in the literature on the presentation, tumor size, response to surgical treatment, and recurrence...
Related ArticlesPediatric cranial deformations: demographic associations. J Neurosurg Pediatr. 2020 May 29;:1-6 Authors: Foster J, Ahluwalia R, Sherburn M, Kelly K, Sellyn GE, Kiely C, Wiseman AL, Gannon S, Shannon CN, Bonfield CM Abstract OBJECTIVE: No study has established a relationship between cranial deformations and demographic factors. While the connection between the Back to Sleep campaign and cranial deformation has been outlined, considerations...
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Related ArticlesSuppression of TRPM7 enhances TRAIL-induced apoptosis in triple-negative breast cancer cells. J Cell Physiol. 2020 May 29;: Authors: Song C, Choi S, Oh KB, Sim T Abstract Transient receptor potential cation channel subfamily M member 7 (TRPM7) composed of an ion channel and a kinase domain regulates triple-negative breast cancer (TNBC) cell migration, invasion, and metastasis, but it does not modulate TNBC proliferation. However, previous...
Related ArticlesArginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. J Cell Physiol. 2020 May 29;: Authors: Yu Y, Ladeiras D, Xiong Y, Boligan KF, Liang X, von Gunten S, Hunger RE, Ming XF, Yang Z Abstract Elevated arginase type II (Arg-II) associates with higher grade tumors. Its function and underlying molecular mechanisms in melanoma remain elusive. In the present study, we observed...
Related ArticlesBMPER is upregulated in obesity and seems to have a role in pericardial adipose stem cells. J Cell Physiol. 2020 May 29;: Authors: Pérez LM, de Lucas B, Gálvez BG Abstract Pericardial adipose tissue (PAT), a visceral fat depot enveloping the heart, is an active endocrine organ and a source of free fatty acids and inflammatory cytokines. As in other fat adult tissues, PAT contains a population of adipose stem cells; however, whether these...
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Related ArticlesMilton L Sunde, PhD: 1921-2015. J Nutr. 2020 May 29;: Authors: Cook ME, Sunde RA PMID: 32470987 [PubMed - as supplied by publisher]
Related ArticlesSupplemental Nicotinamide Dose-Dependently Regulates Body Phosphorus Excretion via Altering Type II Sodium-Phosphate Co-Transporter Expressions in Laying Hens. J Nutr. 2020 May 29;: Authors: Ren ZZ, Yan JK, Pan C, Liu YL, Wen HY, Yang X, Huang XH, Lei XG, Yang XJ Abstract BACKGROUND: Dietary supplemental nicotinamide is used to treat hyperphosphatemia in humans. However, the mechanisms of its impact on body phosphorus homeostasis remain...
Related ArticlesA Chronic Fetal Leucine Infusion Potentiates Fetal Insulin Secretion and Increases Pancreatic Islet Size, Vascularity, and β Cells in Late-Gestation Sheep. J Nutr. 2020 May 29;: Authors: Boehmer BH, Brown LD, Wesolowski SR, Hay WW, Rozance PJ Abstract BACKGROUND: Infusion of a complete amino acid mixture into normal late-gestation fetal sheep potentiates glucose-stimulated insulin secretion (GSIS). Leucine acutely stimulates insulin secretion...
Related ArticlesEnergy Requirement Is Higher During Weight-Loss Maintenance in Adults Consuming a Low- Compared with High-Carbohydrate Diet. J Nutr. 2020 May 29;: Authors: Ebbeling CB, Bielak L, Lakin PR, Klein GL, Wong JMW, Luoto PK, Wong WW, Ludwig DS Abstract BACKGROUND: Longer-term feeding studies suggest that a low-carbohydrate diet increases energy expenditure, consistent with the carbohydrate-insulin model of obesity. However, the validity of...
Related ArticlesDietary Cyanidin-3-Glucoside Attenuates High-Fat-Diet-Induced Body-Weight Gain and Impairment of Glucose Tolerance in Mice via Effects on the Hepatic Hormone FGF21. J Nutr. 2020 May 29;: Authors: Tian L, Ning H, Shao W, Song Z, Badakhshi Y, Ling W, Yang BB, Brubaker PL, Jin T Abstract BACKGROUND: Dietary polyphenols including anthocyanins target multiple organs. OBJECTIVE: We aimed to assess the involvement of glucagon-like peptide...
Related ArticlesDietary Glucose Increases Glucose Absorption and Lipid Deposition via SGLT1/2 Signaling and Acetylated ChREBP in the Intestine and Isolated Intestinal Epithelial Cells of Yellow Catfish. J Nutr. 2020 May 29;: Authors: Zhao T, Yang SB, Chen GH, Xu YH, Xu YC, Luo Z Abstract BACKGROUND: Dietary carbohydrate affects intestinal glucose absorption and lipid deposition, but the underlying mechanisms are unknown. OBJECTIVES: We used...
Related ArticlesFlavonoid Intakes in the US Diet Are Linked to Higher Socioeconomic Status and to Tea Consumption: Analyses of NHANES 2011-16 Data. J Nutr. 2020 May 29;: Authors: Vieux F, Maillot M, Rehm CD, Drewnowski A Abstract BACKGROUND: Many of the health benefits of tea have been attributed to its flavonoid content. Tea consumption in US adults varies by socioeconomic status (SES). OBJECTIVES: The present objective was to explore intakes...
Related ArticlesVitamin B-12 Supplementation during Pregnancy and Early Lactation Does Not Affect Neurophysiologic Outcomes in Children Aged 6 Years. J Nutr. 2020 May 29;: Authors: Srinivasan K, Thomas S, Anand S, Jayachandra M, Thomas T, Strand TA, Kurpad AV, Duggan CP Abstract BACKGROUND: Deficiency of vitamin B-12 is common in pregnant Indian women. Assessment of neurophysiological measures using event-related potentials (ERPs) may yield additional...
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First branchial cleft anomalies are rare, accounting for only 10% of all branchial cleft anomalies. We report an even more rare and unique case of a branchial cleft cyst with features of both first and second ...
Several recent studies have indicated that the lymph node ratio (LNR) is an independent prognostic factor for laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC). The purpose of this paper is to asses...
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Related ArticlesPractice Patterns and Barriers in Botulinum Toxin Injection for the Treatment of Voice Disorders. J Voice. 2020 May 26;: Authors: McGarey PO, Simpson CB, Daniero JJ Abstract Laryngeal botulinum toxin injection is an important treatment modality for spasmodic dysphonia and other laryngeal disorders. We sought to compare usage patterns of laryngeal botulinum toxin injections for voice disorders and to identify and quantify inefficiencies...
Related ArticlesEffect of Muscle Tension Dysphonia on Self-perceived Voice Handicap and Multiparametric Measurement and Their Relation in Female Teachers. J Voice. 2020 May 25;: Authors: Aghadoost S, Jalaie S, Dabirmoghaddam P, Khoddami SM Abstract OBJECTIVES: Muscle tension dysphonia (MTD) is a common voice disorder in teachers in which subjective and objective dimensions of quality of voice can be impaired. The study aimed to compare voice handicap...
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Related ArticlesUniqueness of Laryngeal Nerve Injury Following Heart Transplantation. J Heart Lung Transplant. 2020 Apr;39(4S):S280 Authors: de la Rosa A, Aguilar J, Barbu A, Chang D, Kobashigawa J Abstract PURPOSE: The incidence of recurrent laryngeal nerve injury after heart transplantation has not been well studied. Recurrent laryngeal nerve injury manifests as absent or impaired vocal cord mobility causing dysphonia. Few studies have evaluated this...
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Related ArticlesIntratumor heterogeneity in human parathyroid tumors. Histol Histopathol. 2020 May 29;:18230 Authors: Verdelli C, Tavanti GS, Corbetta S Abstract Parathyroid tumors are the second most common endocrine neoplasia after thyroid neoplasia. They are mostly associated with impaired parathormone (PTH) synthesis and release determining the metabolic and clinical condition of primary hyperparathyroidism (PHPT). PHPT is the third most prevalent...
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The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The integration of MRI and PT at the treatmen...
Radiosensitivity is limited in cervical cancer (CC) patients due to acquired radiation resistance. In our previous studies, we found that immediate-early response 5 (IER5) is upregulated in CC cells upon radia...
The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduc...
PTV concept is presumed to introduce excessive and inconsistent GTV dose in lung stereotactic body radiotherapy (SBRT). That GTV median dose prescription (D50) and robust optimization are viable PTV–free solution...
Hypofractionated-SRS (HF-SRS) may allow for improved local control and a reduced risk of radiation necrosis compared to single-fraction-SRS (SF-SRS). However, data comparing these two treatment approaches are ...
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Related ArticlesThe RECARDINA Study protocol: diagnostic utility of ultra-abbreviated echocardiographic protocol for handheld machines used by non-experts to detect rheumatic heart disease. BMJ Open. 2020 May 27;10(5):e037609 Authors: Francis JR, Fairhurst H, Whalley G, Kaethner A, Ralph A, Yan J, Cush J, Wade V, Monteiro A, Remenyi B Abstract INTRODUCTION: Rheumatic heart disease (RHD) causes significant morbidity and mortality in young people from...
Related ArticlesPerception of modern radiotherapy learning: study protocol for a mixed-methods analysis of trainees and trainers at a UK cancer centre. BMJ Open. 2020 May 27;10(5):e037171 Authors: Walls G, McAleer JJ, Hanna GG Abstract INTRODUCTION: Radiotherapy technology and postgraduate medical training have both evolved significantly over the last 20 years. Clinical Oncology is a recognised craft specialty where the apprenticeship model of clinical...
Related ArticlesTracing frequent users of regional care services using emergency medical services data: a networked approach. BMJ Open. 2020 May 27;10(5):e036139 Authors: Maruster L, van der Zee DJ, Hatenboer J, Buskens E Abstract OBJECTIVES: This study shows how a networked approach relying on 'real-world' emergency medical services (EMS) records might contribute to tracing frequent users of care services on a regional scale. Their tracing is considered...
Related ArticlesMethodological aspects of economic evaluations conducted in the palliative or end of life care settings: a systematic review protocol. BMJ Open. 2020 May 27;10(5):e035760 Authors: Fischer C, Chwala E, Simon J Abstract INTRODUCTION: In light of this growing palliative care and end of life care patient population, as well as new (expensive) drugs and treatments, quality research providing evidence for decision-making is required. However,...
Related ArticlesPublic satisfaction with the healthcare system in China during 2013-2015: a cross-sectional survey of the associated factors. BMJ Open. 2020 May 27;10(5):e034414 Authors: Zhang JH, Peng X, Liu C, Chen Y, Zhang H, Iwaloye OO Abstract OBJECTIVE: We explore how public satisfaction with the healthcare system in China varies with social and economic factors, especially regional variations and changes during 2013-2015. DESIGN: Population-based,...
Related ArticlesCohort profile: the LHIV-Manitoba clinical cohort of people living with HIV in Manitoba, Canada. BMJ Open. 2020 May 27;10(5):e034259 Authors: McClarty LM, Cheuk E, Ireland L, Kendall C, Bibeau C, Loeppky C, Kasper K, Keynan Y, Blanchard J, Becker M Abstract PURPOSE: The LHIV-Manitoba cohort was developed as a way to provide a comprehensive source of HIV-related health information in the central Canadian Prairie province of Manitoba. The...
Related ArticlesImpact of community-based chronic obstructive pulmonary disease service, a multidisciplinary intervention in an area of high deprivation: a longitudinal matched controlled study. BMJ Open. 2020 May 27;10(5):e032931 Authors: Saini P, Rose T, Downing J, Matata B, Pilsworth S, Pemberton A, Comerford T, Wilson K, Shaw M, Harper LM, Daras K, Barr B Abstract OBJECTIVE: To examine the effects of a consultant-led, community-based chronic obstructive...
Related ArticlesNomogram for contrast-induced acute kidney injury in patients with chronic kidney disease undergoing coronary angiography in China: a cohort study. BMJ Open. 2020 May 26;10(5):e037256 Authors: Lei L, Xue Y, Guo Z, Liu B, He Y, Liu J, Nie Z, Chen L, Chen K, Huang Z, Liang M, Chen S, Liu Y, Chen J Abstract OBJECTIVES: To establish a nomogram for contrast-induced acute kidney injury (CI-AKI) risk assessment among patients with chronic kidney...
Related ArticlesProtocol for hypofractionated adaptive radiotherapy to the bladder within a multicentre phase II randomised trial: radiotherapy planning and delivery guidance. BMJ Open. 2020 May 26;10(5):e037134 Authors: Hafeez S, Patel E, Webster A, Warren-Oseni K, Hansen V, McNair H, Miles E, Lewis R, Hall E, Huddart R Abstract INTRODUCTION: Patients with muscle invasive bladder cancer (MIBC) who are unfit and unsuitable for standard radical treatment...
Related ArticlesLengthening adalimumab dosing interval in quiescent Crohn's disease patients: protocol for the pragmatic randomised non-inferiority LADI study. BMJ Open. 2020 May 26;10(5):e035326 Authors: Smits LJT, Pauwels RWM, Kievit W, de Jong DJ, de Vries AC, Hoentjen F, van der Woude CJ, LADI study group Abstract INTRODUCTION: Adalimumab is effective for maintenance of remission in patients with Crohn's disease (CD) at a dose of 40 mg subcutaneously...
Related ArticlesMental health among Ebola survivors in Liberia, Sierra Leone and Guinea: results from a cross-sectional study. BMJ Open. 2020 May 26;10(5):e035217 Authors: Secor A, Macauley R, Stan L, Kagone M, Sidikiba S, Sow S, Aronovich D, Litvin K, Davis N, Alva S, Sanderson J Abstract OBJECTIVES: To describe the prevalence and correlates of depression and anxiety among adult Ebola virus disease (EVD) survivors in Liberia, Sierra Leone and Guinea....
Related Articles'Surely you're not still breastfeeding': a qualitative exploration of women's experiences of breastfeeding beyond infancy in the UK. BMJ Open. 2020 May 26;10(5):e035199 Authors: Thompson AJ, Topping AE, Jones LL Abstract OBJECTIVES: To explore women's experiences of breastfeeding beyond infancy (>1 year). Understanding these experiences, including the motivators, enablers and barriers faced, may help inform future strategies to support...
Related ArticlesRole of requests and communication breakdowns in the coordination of teamwork: a video-based observational study of hybrid operating rooms. BMJ Open. 2020 May 26;10(5):e035194 Authors: Ivarsson J, Åberg M Abstract OBJECTIVES: This study investigated the functional role of 'requests' in the coordination of surgical activities in the operating room (OR). A secondary aim was to describe, closely, instances of potential miscommunication to...
Related ArticlesAsylum seekers' and Refugees' Changing Health (ARCH) study protocol: an observational study in Lebanon and Denmark to assess health implications of long-distance migration on communicable and non-communicable diseases and mental health. BMJ Open. 2020 May 26;10(5):e034412 Authors: Eiset AH, Aoun MP, Haddad RS, Naja WJ, Fuursted K, Nielsen HV, Stensvold CR, Nielsen MS, Gottlieb A, Frydenberg M, Wejse C Abstract INTRODUCTION: By end of...
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