Related ArticlesEffects of an ethyl acetate extract of Daphne altaica stem bark on the cell cycle, apoptosis and expression of PPARγ in Eca‑109 human esophageal carcinoma cells. Mol Med Rep. 2020 May 27;: Authors: Kizaibek M, Wubuli A, Gu Z, Bahetjan D, Tursinbai L, Nurhamit K, Chen B, Wang J, Tahan O, Cao P Abstract Daphne altaica Pall. (D. altaica; Thymelaeaceae) has long been used in traditional Kazakh medicine for the treatment of cancer and...
Sat May 30, 2020 13:06
Related ArticlesCharacterization of KIF20A as a prognostic biomarker and therapeutic target for different subtypes of breast cancer. Int J Oncol. 2020 May 07;: Authors: Nakamura M, Takano A, Thang PM, Tsevegjav B, Zhu M, Yokose T, Yamashita T, Miyagi Y, Daigo Y Abstract The aim of the present study was to identify novel prognostic biomarkers and therapeutic targets for breast cancer; thus, genes that are frequently overexpressed in several types...
Sat May 30, 2020 13:06
Related ArticlesImmunomodulatory MicroRNAs in cancer: targeting immune checkpoints and the tumor microenvironment. FEBS J. 2019 09;286(18):3540-3557 Authors: Omar HA, El-Serafi AT, Hersi F, Arafa EA, Zaher DM, Madkour M, Arab HH, Tolba MF Abstract Cancer immunotherapy represents a promising new era in cancer management due to the relatively high safety margins and selectivity, compared to the classical cancer chemotherapeutic agents. However, there...
Sat May 30, 2020 13:06
Related ArticlesInhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter. Neuroendocrinology. 2019;109(4):362-373 Authors: Ciato D, Li R, Monteserin Garcia JL, Papst L, D'Annunzio S, Hristov M, Tichomirowa MA, Belaya Z, Rozhinskaya L, Buchfelder M, Theodoropoulou M, Paez-Pereda M, Stalla GK Abstract BACKGROUND: Cushing's disease (CD) is caused by adrenocorticotropic hormone (ACTH)-secreting pituitary tumours. They...
Sat May 30, 2020 13:06
Related ArticlesCircular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820928471 Authors: Peng Z, Xu B, Jin F Abstract This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer. The circular RNA expression microarray "GSE101123" related to breast...
Fri May 29, 2020 13:20
Related ArticlesIntegrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma. Biomed Res Int. 2020;2020:8657468 Authors: Meng X, Wang L, Zhu B, Zhang J, Guo S, Li Q, Zhang T, Zheng Z, Wu G, Zhao Y Abstract ATPase family AAA domain-containing protein 2 (ATAD2), a chromatin regulator and an oncogenic transcription cofactor, is frequently overexpressed in many cancers, particularly in hepatocellular...
Fri May 29, 2020 13:20
Related ArticlesAnti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases. Pharmacol Res. 2020 May 13;158:104901 Authors: Cheong DHJ, Tan DWS, Wong FWS, Tran T Abstract Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatment of fever and chills, and has been recently approved for the treatment of malaria due...
Fri May 29, 2020 13:20
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement.
Related ArticlesMolecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement. Semin Cancer Biol. 2020 May 24;: Authors: Aggarwal V, Tuli HS, Tania M, Srivastava S, Ritzer EE, Pandey A, Aggarwal D, Barwal TS, Jain A, Kaur G, Sak K, Varol M, Bishayee A Abstract Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of epigallocatechin and gallic acid. EGCG, abundantly found in tea,...
Fri May 29, 2020 13:20
Related Articles3,3',5,5'-tetramethoxybiphenyl-4,4'diol induces cell cycle arrest in G2/M phase and apoptosis in human non-small cell lung cancer A549 cells. Chem Biol Interact. 2020 May 24;:109133 Authors: Concato VM, Tomiotto-Pellissier F, Silva TF, Gonçalves MD, da Silva Bortoleti BT, Detoni MB, da Silva Siqueira E, Jacob Rodrigues AC, Schirmann JG, de Melo Barbosa-Dekker A, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Mantovani MS, Pavanelli WR Abstract...
Fri May 29, 2020 13:20
Related ArticlesHaematological immune-related adverse events with immune checkpoint inhibitors, how to manage? Eur J Cancer. 2019 11;122:72-90 Authors: Michot JM, Lazarovici J, Tieu A, Champiat S, Voisin AL, Ebbo M, Godeau B, Michel M, Ribrag V, Lambotte O Abstract Immune checkpoint inhibitors (ICIs) are changing the treatments of many patients with cancer. These immunotherapies are generally better tolerated than chemotherapy, and their adverse events...
Fri May 29, 2020 13:20
Related ArticlesPreclinical models of breast cancer: Two-way shuttles for immune checkpoint inhibitors from and to patient bedside. Eur J Cancer. 2019 11;122:22-41 Authors: Abdel-Aziz AK, Saadeldin MK, D'Amico P, Orecchioni S, Bertolini F, Curigliano G, Minucci S Abstract The Food and Drug Administration has lately approved atezolizumab, anti-programmed death ligand 1 (PD-L1), to be used together with nanoparticle albumin-bound (nab) paclitaxel in treating...
Fri May 29, 2020 13:20
Related ArticlesImmunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis: Progress and Future Directions. Chest. 2019 12;156(6):1062-1067 Authors: Liu HJ, Krymskaya VP, Henske EP Abstract Pulmonary lymphangioleiomyomatosis (LAM) is a rare genetic multisystem disease characterized by the nodular proliferation of smooth muscle-like LAM cells, progressive cystic changes of the lung, lymphatic abnormalities, and renal angiomyolipomas (AMLs). LAM...
Fri May 29, 2020 13:20
Related ArticlesImmune checkpoint inhibitor-induced Type 1 diabetes: a systematic review and meta-analysis. Diabet Med. 2019 09;36(9):1075-1081 Authors: Akturk HK, Kahramangil D, Sarwal A, Hoffecker L, Murad MH, Michels AW Abstract AIM: To conduct a systematic review and meta-analysis to understand the timing and factors associated with anti-programmed cell death protein-1 (PD-1)/anti-programmed cell death protein-1 ligand (PD-L1) inhibitor-induced...
Fri May 29, 2020 13:20
Emerging treatment options for hemophilia, including gene therapy, modified factor products, antibody‐based products, and other nonreplacement therapies, are in development or on their way to marketing authorization. For proof of efficacy, annual bleeding rates (ABRs) have become an increasingly important endpoint in hemophilia trials. We hypothesized that ABR analyses differ substantially between and within medicinal product classes and that the ABR observation period constitutes a major bias. For...
Sat May 30, 2020 18:03
Related ArticlesEconomic implications of the COVID-19 pandemic on the plastic surgery community. J Plast Reconstr Aesthet Surg. 2020 May 23;: Authors: Inglesby DC, Boyd CJ PMID: 32471766 [PubMed - as supplied by publisher]
Sun May 31, 2020 13:47
Related ArticlesEvolution of plastic surgery provision due to COVID-19 - The role of the 'Pandemic pack'. J Plast Reconstr Aesthet Surg. 2020 May 21;: Authors: Ali SR, Jovic T, Gibson JA, Rich H, Jessop ZM, Whitaker IS PMID: 32471765 [PubMed - as supplied by publisher]
Sun May 31, 2020 13:47
Related ArticlesImproving evaluation methods and study population to assess the educational value of the virtual 3D anterolateral thigh model. J Plast Reconstr Aesthet Surg. 2020 May 17;: Authors: Chu TSM, Fan KS PMID: 32471764 [PubMed - as supplied by publisher]
Sun May 31, 2020 13:47
Related ArticlesRisk Factors for Complications and Long-Term Outcomes Following Completion Lymph Node Dissection for Cutaneous Melanoma: A Retrospective Cohort Study. J Plast Reconstr Aesthet Surg. 2020 Mar 17;: Authors: Sars C, Gillgren P, Schultz I, Lindqvist EK Abstract BACKGROUND: Completion lymph node dissection (CLND) for malignant melanoma is performed for regional cancer control and is associated with a high complication rate. It is unknown whether...
Sat May 30, 2020 13:58
Related ArticlesThe Adipofascial Deltopectoral Flap to Cover the Brachial Plexus in Thoracic Outlet Syndrome and Radiation Plexitis. J Plast Reconstr Aesthet Surg. 2020 Mar 13;: Authors: Dolan RT, Moosa A, Giele HP Abstract Revascularisation of the brachial plexus is controversial. Traditional techniques use free tissue transfer of omentum, groin fat or muscle, on the principle of supplying rich quantities of vascularised tissue to wrap around the nerves...
Sat May 30, 2020 13:58
Related ArticlesRobotic-assisted latissimus dorsi muscle flap for autologous chest reconstruction in poland syndrome. J Plast Reconstr Aesthet Surg. 2020 Jan 31;: Authors: Moon KC, Yeo HD, Yoon ES, Lee BI, Park SH, Chung JH, Lee HC Abstract BACKGROUND: As chest reconstructions in Poland syndrome are performed for patients at young ages, patients are generally concerned about conspicuous scars. Meanwhile, a robotic-assisted latissimus dorsi (LD) muscle...
Fri May 29, 2020 14:19
Related ArticlesAssociation Between Breathing Route, Oxygen Desaturation, and Upper Airway Morphology. Laryngoscope. 2020 May 30;: Authors: Hsu YB, Lan MY, Huang YC, Kao MC, Lan MC Abstract OBJECTIVES/HYPOTHESIS: This study aimed to assess the role of capnography in objectively evaluating breathing routes during drug-induced sleep endoscopy (DISE) and further elucidate the relationship between breathing route, obstructive sleep apnea (OSA) severity,...
Sun May 31, 2020 16:20
Variation in Sleep Stability with Differences in Severity of Sleep-Disordered Breathing in Children.
Related ArticlesVariation in Sleep Stability with Differences in Severity of Sleep-Disordered Breathing in Children. Laryngoscope. 2020 May 30;: Authors: Seo MY, Han MS, Jeong YJ, Lee MK, Park S, Hwang SJ, Lee SH Abstract OBJECTIVES: The aim of this study was to analyze the association between obstructive sleep apnea (OSA) severity and various cardiopulmonary coupling (CPC) parameters in children with OSA. STUDY DESIGN: Retrospective cross-sectional...
Sun May 31, 2020 16:20
Related ArticlesA COVID-19 Conundrum: Obstructive Sleep Apnea (OSA) and Non-Invasive Ventilation (NIV). Anesth Analg. 2020 May 27;: Authors: Abstract The challenges imposed by the COVID-19 pandemic become amplified in the setting of non-intubated patients with obstructive sleep apnea. Unlike the closed system that characterizes an intubated patient attached to a respiratory circuit, non-invasive ventilatory support threatens an increased risk of permeating...
Sun May 31, 2020 16:20
Related ArticlesA Modified Cosmetic Genioplasty Can Affect Airway Space Positively in Skeletal Class II Patients: Studying Alterations of Hyoid Bone Position and Posterior Airway Space. Aesthetic Plast Surg. 2020 May 29;: Authors: Chen K, Sun X, Wang L, Ni S, Wu Z, Gao Y, Wang X, Xie K, Liu S, Wu G Abstract BACKGROUND: Improving the posterior airway space is one of the most important functions of genioplasty. Studies have shown that the posterior airway...
Sun May 31, 2020 13:39
Related ArticlesHeadache in the Older Population: Causes, Diagnoses, and Treatments. Curr Pain Headache Rep. 2020 May 29;24(7):34 Authors: Robblee J, Singh RH Abstract PURPOSE OF REVIEW: Primary headaches are less common and differ in presentation in older versus younger individuals. Secondary headaches become more common among older patients. RECENT FINDINGS: Diagnosis and management of headaches in those > 65 years are discussed. Migraine...
Sun May 31, 2020 13:39
Related ArticlesCPAP is associated with decreased risk of AF recurrence in patients with OSA, especially those younger and slimmer: a meta-analysis. J Interv Card Electrophysiol. 2020 May 29;: Authors: Yang Y, Ning Y, Wen W, Jia Y, Chen X, Huang M, Sara JD, Qin Y, Fang F, Zhang H, Du Y, Li L, Jiao X, Yang Y, Han X, Zhang M, Wei Y Abstract PURPOSE: Obstructive sleep apnea (OSA) is associated with the management of atrial fibrillation (AF). This manuscript...
Sun May 31, 2020 13:39
Related ArticlesPhenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study. Diabetologia. 2020 May 29;: Authors: Cariou B, Hadjadj S, Wargny M, Pichelin M, Al-Salameh A, Allix I, Amadou C, Arnault G, Baudoux F, Bauduceau B, Borot S, Bourgeon-Ghittori M, Bourron O, Boutoille D, Cazenave-Roblot F, Chaumeil C, Cosson E, Coudol S, Darmon P, Disse E, Ducet-Boiffard A, Gaborit B, Joubert M, Kerlan V, Laviolle B, Marchand L, Meyer L,...
Sun May 31, 2020 13:39
Related ArticlesThe Neuropsychological Profile of Attention Deficits of Patients with Obstructive Sleep Apnea: An Update on the Daytime Attentional Impairment. Brain Sci. 2020 May 27;10(6): Authors: Angelelli P, Macchitella L, Toraldo DM, Abbate E, Marinelli CV, Arigliani M, De Benedetto M Abstract INTRODUCTION: Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive disturbances. One of the neuropsychological processes most investigated...
Sun May 31, 2020 13:39
Related ArticlesEstimation of the hyperelastic parameters of fresh human oropharyngeal soft tissues using indentation testing. J Mech Behav Biomed Mater. 2020 Aug;108:103798 Authors: Haddad SMH, Dhaliwal SS, Rotenberg BW, Ladak HM, Samani A Abstract Patient-specific finite element (FE) modeling of the upper airway is an effective tool for accurate assessment of obstructive sleep apnea (OSA) syndrome. It is also useful for planning minimally invasive...
Sat May 30, 2020 15:41
Related ArticlesEvaluation of neurocognitive abilities in children affected by obstructive sleep apnea syndrome before and after adenotonsillectomy. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):122-132 Authors: Testa D, Carotenuto M, Precenzano F, Russo A, Donadio A, Marcuccio G, Motta G PMID: 32469006 [PubMed - in process]
Sat May 30, 2020 15:41
Related ArticlesSleep Disorders and Restless Legs Syndrome in Hemodialysis Patients in Greece: A Cross-Sectional Study. Adv Exp Med Biol. 2020;1195:155-162 Authors: Stergiannis P, Govari M, Jahaj E, Marvaki C, Toulia G, Marvaki K, Chasioti G, Intas G Abstract INTRODUCTION: Sleep disorders, including insomnia and extreme sleep times, adversely affect the risk of developing illnesses and contribute to increased mortality rates. The aim of the study was...
Sat May 30, 2020 13:16
Related ArticlesA detection dog for obstructive sleep apnea: could it work in diagnostics? Sleep Breath. 2020 May 29;: Authors: Vaarno J, Myller J, Bachour A, Koskinen H, Bäck L, Klockars T, Koskinen A Abstract PURPOSE: We have previously demonstrated that dogs can be trained to distinguish the urine of patients with obstructive sleep apnea (OSA) from that of healthy controls based on olfaction. Encouraged by these promising results, we wanted to investigate...
Sat May 30, 2020 13:16
Related ArticlesRelationship between HIF-1 and Circadian Clock Proteins in Obstructive Sleep Apnea Patients-Preliminary Study. J Clin Med. 2020 May 25;9(5): Authors: Gabryelska A, Sochal M, Turkiewicz S, Białasiewicz P Abstract Obstructive sleep apnea (OSA) is characterized by intermittent hypoxia and associated with the disruption of circadian rhythm. The study aimed to assess the relationship between hypoxia-inducible factor (HIF) subunits, circadian...
Sat May 30, 2020 13:16
Related ArticlesThe Differentiation of Etiologies of Pulmonary Arterial Hypertension amongst Males and Females. J Heart Lung Transplant. 2020 Apr;39(4S):S510 Authors: Kaur B, Garcia RA, Gaznabi S, Siddiqui OM, Kim CH, Balakumaran K, Schilz R, Amm CE Abstract PURPOSE: There are limited studies which have studied the etiological differentiation of pulmonary arterial hypertension in large patient sample. OBJECTIVE: To understand the association...
Sat May 30, 2020 13:16
Related ArticlesPeak Oxygen Consumption and Survival after Heart Transplant is Similar in Patients with and without Comorbid Obstructive Sleep Apnea. J Heart Lung Transplant. 2020 Apr;39(4S):S257 Authors: Genuardi MV, Zhang Y, Mazurek JA, Hanff TC, Molina M, Atluri P, Zamani P, McLean R, Goldberg LR, Birati EY Abstract PURPOSE: Obstructive sleep apnea (OSA) is associated with increased all-cause and cardiovascular mortality in the general population...
Sat May 30, 2020 13:16
Related ArticlesAssociation between central sleep apnea and atrial fibrillation/flutter in Japanese-American men: The Kuakini Honolulu Heart Program (HHP) and Honolulu-Asia Aging Study (HAAS). J Electrocardiol. 2020 May 12;61:10-17 Authors: Anzai T, Grandinetti A, Katz AR, Hurwitz EL, Wu YY, Masaki K Abstract INTRODUCTION: While several studies have indicated that central sleep apnea (CSA) is associated with atrial fibrillation and atrial flutter (AF)...
Fri May 29, 2020 15:36
Related ArticlesSleep disordered breathing in adults living with a Fontan circulation and CPAP titration protocol. Int J Cardiol. 2020 May 25;: Authors: Nanayakkara B, Lau E, Yee B, Gauthier G, Melehan K, Celermajer D, Cordina R Abstract BACKGROUND: Fontan-type single ventricle physiology has exquisite respiratory dependence. Obstructive sleep apnoea (OSA) and continuous positive airway pressure (CPAP) are likely to have deleterious haemodynamic consequences....
Fri May 29, 2020 15:36
Related ArticlesBelun Ring Platform: a novel home sleep apnea testing system for assessment of obstructive sleep apnea. J Clin Sleep Med. 2020 May 22;: Authors: Gu W, Leung L, Kwok KC, Wu IC, Folz RJ, Chiang AA Abstract STUDY OBJECTIVES: The objective of the study is to validate the performance of Belun Ring Platform, a novel home sleep apnea testing system using a patented pulse oximeter sensor and a proprietary cloud-based neural networks algorithm....
Fri May 29, 2020 15:36
Related ArticlesDo Young Children With Nonsevere Obstructive Sleep Apnea Benefit From Adenotonsillectomy?: The CHAT vs the KATE Study. JAMA Otolaryngol Head Neck Surg. 2020 May 28;: Authors: Baldassari CM PMID: 32463442 [PubMed - as supplied by publisher]
Fri May 29, 2020 13:11
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