Toxins, Vol. 12, Pages 359: RTX-Toxins Toxins doi: 10.3390/toxins12060359 Authors: Roland Benz RTX-Toxins (Repeats in ToXin) are members of a rapidly expanding family of proteins [...]
Sat May 30, 2020 03:00
Toxins, Vol. 12, Pages 360: The Virulence Potential of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Cultured from the Airways of Cystic Fibrosis Patients Toxins doi: 10.3390/toxins12060360 Authors: Treffon Fotiadis van Alen Becker Kahl Staphylococcus aureus is one of the most common pathogens that infects the airways of patients with cystic fibrosis (CF) and contributes to respiratory failure. Recently, livestock-associated methicillin-resistant S....
Sat May 30, 2020 03:00
Toxins, Vol. 12, Pages 356: PLA2 Inhibitor Varespladib as an Alternative to the Antivenom Treatment for Bites from Nikolsky’s Viper Vipera berus nikolskii Toxins doi: 10.3390/toxins12060356 Authors: Oleksandr Zinenko Igor Tovstukha Yevgen Korniyenko Although envenoming by a small East European species of viper is rarely severe, and only exceptionally fatal, lack of specific antivenom stocks in a few areas within this region and possible severe side effects of antivenom application...
Fri May 29, 2020 03:00
Toxins, Vol. 12, Pages 357: Multi Mycotoxin Determination in Dried Beef Using Liquid Chromatography Coupled with Triple Quadrupole Mass Spectrometry (LC-MS/MS) Toxins doi: 10.3390/toxins12060357 Authors: Toluwase Adeseye Dada Theodora Ijeoma Ekwomadu Mulunda Mwanza Dried beef meat, a locally processed meat from the cow, is vulnerable to contamination by mycotoxins, due to its exposure to the environmental microbiota during processing, drying, and point of sale. In this study, 108...
Fri May 29, 2020 03:00
Toxins, Vol. 12, Pages 355: Potential of Cry10Aa and Cyt2Ba, Two Minority δ-endotoxins Produced by Bacillus thuringiensis ser. israelensis, for the Control of Aedes aegypti Larvae Toxins doi: 10.3390/toxins12060355 Authors: Daniel Valtierra-de-Luis Maite Villanueva Liliana Lai Trevor Williams Primitivo Caballero Bacillus thuringiensis ser. israelensis (Bti) has been widely used as microbial larvicide for the control of many species of mosquitoes and blackflies. The larvicidal...
Fri May 29, 2020 03:00
Toxins, Vol. 12, Pages 358: The Procoagulant Snake Venom Serine Protease Potentially Having a Dual, Blood Coagulation Factor V and X-Activating Activity Toxins doi: 10.3390/toxins12060358 Authors: Zorica Latinović Adrijana Leonardi Cho Yeow Koh R. Manjunatha Kini Alenka Trampuš Trampuš Bakija Jože Pungerčar Igor Križaj A procoagulant snake venom serine protease was isolated from the venom of the nose-horned viper (Vipera ammodytes ammodytes). This 34 kDa glycoprotein,...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 267: Game Analysis on the Evolution of Decision-Making of Vaccine Manufacturing Enterprises under the Government Regulation Model Vaccines doi: 10.3390/vaccines8020267 Authors: Na Zhang Yingjie Yang Xiaodong Wang Xinfeng Wang The harm caused by defective vaccines to human health and social stability is immeasurable. Aiming at the government’s supervision of the vaccine market, an evolutionary game model is constructed to analyze the quality...
Sun May 31, 2020 03:00
Vaccines, Vol. 8, Pages 266: Current Status of Zika Virus Vaccines: Successes and Challenges Vaccines doi: 10.3390/vaccines8020266 Authors: Pattnaik Sahoo Pattnaik The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) in adults. The unprecedented nature of the epidemic and serious diseases associated with the viral infections prompted the global...
Sun May 31, 2020 03:00
Vaccines, Vol. 8, Pages 265: Seasonal Influenza Vaccination and Recommendation: The Difference between General Practitioners and Public Health Workers in China Vaccines doi: 10.3390/vaccines8020265 Authors: Rong Lai Ma Hou Li Jing Zhang Peng Feng Fang Seasonal influenza vaccination for healthcare workers (HCWs) is critical to the protection of HCWs and their patients. This study examined whether the separation of public health workers and general...
Sun May 31, 2020 03:00
Vaccines, Vol. 8, Pages 264: Role of Opsonophagocytosis in Immune Protection against Malaria Vaccines doi: 10.3390/vaccines8020264 Authors: Leitner Haraway Pierson Bergmann-Leitner The quest for immune correlates of protection continues to slow vaccine development. To date, only vaccine-induced antibodies have been confirmed as direct immune correlates of protection against a plethora of pathogens. Vaccine immunologists, however, have learned through extensive characterizations...
Sat May 30, 2020 03:00
Vaccines, Vol. 8, Pages 263: Impact of Influenza Vaccination on All-Cause Mortality and Hospitalization for Pneumonia in Adults and the Elderly with Diabetes: A Meta-Analysis of Observational Studies Vaccines doi: 10.3390/vaccines8020263 Authors: Bechini Ninci Del Riccio Biondi Bianchi Bonanni Mannucci Monami Diabetes is a chronic condition that can be worsened by complications such as seasonal influenza virus infections. The aim of the present meta-analysis...
Sat May 30, 2020 03:00
Vaccines, Vol. 8, Pages 262: Deletion of the Gene for the Type I Interferon Inhibitor I329L from the Attenuated African Swine Fever Virus OURT88/3 Strain Reduces Protection Induced in Pigs Vaccines doi: 10.3390/vaccines8020262 Authors: Reis Goatley Jabbar Lopez Rathakrishnan Dixon Live attenuated vaccines are considered to be the fastest route to the development of a safe and efficacious African swine fever (ASF) vaccine. Infection with the naturally attenuated OURT88/3...
Sat May 30, 2020 03:00
Vaccines, Vol. 8, Pages 255: HSV-1-Specific IgG3 Titers Correlate with Brain Cortical Thinning in Individuals with Mild Cognitive Impairment and Alzheimer’s Disease Vaccines doi: 10.3390/vaccines8020255 Authors: Roberta Mancuso Monia Cabinio Simone Agostini Francesca Baglio Mario Clerici Repeated reactivations of latent herpes simplex virus type-1 (HSV-1) in the central nervous system (CNS) may contribute to neurodegeneration in Alzheimer’s disease (AD) patients....
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 258: Protective Efficacy of a Chimeric Insect-Specific Flavivirus Vaccine against West Nile Virus Vaccines doi: 10.3390/vaccines8020258 Authors: Laura J. Vet Yin Xiang Setoh Alberto A. Amarilla Gervais Habarugira Willy W. Suen Natalee D. Newton Jessica J. Harrison Jody Hobson-Peters Roy A. Hall Helle Bielefeldt-Ohmann Virulent strains of West Nile virus (WNV) are highly neuro-invasive and human infection is potentially lethal. However,...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 260: Specificity of CD8+ T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya Vaccines doi: 10.3390/vaccines8020260 Authors: Yehia S. Mohamed Nicola J. Borthwick Nathifa Moyo Hayato Murakoshi Tomohiro Akahoshi Francesca Siliquini Zara Hannoun Alison Crook Peter Hayes Patricia E. Fast Gaudensia Mutua Walter Jaoko Sandra Silva-Arrieta Anuska Llano Christian Brander Masafumi Takiguchi Tomáš...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 261: Biodegradable PLGA-b-PEG Nanoparticles Induce T Helper 2 (Th2) Immune Responses and Sustained Antibody Titers via TLR9 Stimulation Vaccines doi: 10.3390/vaccines8020261 Authors: Kirsty L. Wilson Gregory P. Howard Heather Coatsworth Rhoel R. Dinglasan Hai-Quan Mao Magdalena Plebanski Sustained immune responses, particularly antibody responses, are key for protection against many endemic infectious diseases. Antibody responses are often accompanied...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 259: Intranasal Therapeutic Peptide Vaccine Promotes Efficient Induction and Trafficking of Cytotoxic T Cell Response for the Clearance of HPV Vaginal Tumors Vaccines doi: 10.3390/vaccines8020259 Authors: Gloria Sierra Stephanie Dorta-Estremera Venkatesh L. Hegde Sita M. K. Nookala Ananta V. Yanamandra K. Jagannadha Sastry Human papillomavirus (HPV)-induced cancers continue to affect millions of women around the world, and the five year survival...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 257: Immunization with Bovine Serum Albumin (BSA) in Oil-Adjuvant Elicits IgM Antibody Response in Chinese Soft-Shelled Turtle (Pelodiscus Sinensis) Vaccines doi: 10.3390/vaccines8020257 Authors: Cheng Xu Jiehao Xu Yu Chen Øystein Evensen Hetron Mweemba Munang’andu Guoying Qian Immunoassays are among the frontline methods used for disease diagnosis and surveillance. Despite this, there are no immunoassays developed for the Chinese soft-shelled turtle...
Fri May 29, 2020 03:00
Vaccines, Vol. 8, Pages 256: West Nile Virus Restriction in Mosquito and Human Cells: A Virus under Confinement Vaccines doi: 10.3390/vaccines8020256 Authors: Marie-France Martin Sébastien Nisole West Nile virus (WNV) is an emerging neurotropic flavivirus that naturally circulates between mosquitoes and birds. However, WNV has a broad host range and can be transmitted from mosquitoes to several mammalian species, including humans, through infected saliva during a blood meal. Although...
Fri May 29, 2020 03:00
Veterinary Sciences, Vol. 7, Pages 70: Immunohistochemical Studies of Cytokeratins and Differentiation Markers in Bovine Ocular Squamous Cell Carcinoma Veterinary Sciences doi: 10.3390/vetsci7020070 Authors: Helena Vala Tânia Carvalho Carlos Pinto Maria A. Pereira João R. Mesquita Maria C. C. Peleteiro Lluís Ferrer Dolores Fondevila Bovine Ocular Squamous Cell Carcinoma is considered the most common bovine tumour, causing significant economic losses, mainly by abattoir...
Fri May 29, 2020 03:00
Viruses, Vol. 12, Pages 603: Fatal Dengue Cases Reveal Brain Injury and Viral Replication in Brain-Resident Cells Associated with the Local Production of Pro-Inflammatory Mediators Viruses doi: 10.3390/v12060603 Authors: Salomão Rabelo Basílio-de-Oliveira Basílio-de-Oliveira Geraldo Lima dos Santos Nuovo Oliveira Paes Dengue is an arboviral disease caused by dengue virus (DENV), which is transmitted to humans by Aedes aegypti mosquitoes. Infection...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 602: Complete Sequence, Genome Organization and Molecular Detection of Grapevine Line Pattern Virus, a New Putative Anulavirus Infecting Grapevine Viruses doi: 10.3390/v12060602 Authors: Elbeaino Kontra Demian Jaksa-Czotter Slimen Fabian Lazar Tamisier Digiaro Massart Varallyay : Grapevine line pattern virus (GLPV) was first described 30 years ago in Hungary. The lack of its genomic sequences and of an available antiserum...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 604: Identification and Functional Analysis of Temperate Siphoviridae Bacteriophages of Acinetobacter baumannii Viruses doi: 10.3390/v12060604 Authors: Shimaa Badawy Maria I. Pajunen Johanna Haiko Zakaria A. M. Baka Mohamed I. Abou-Dobara Ahmed K. A. El-Sayed Mikael Skurnik Acinetobacter baumannii is an opportunistic pathogen that presents a serious clinical challenge due to its increasing resistance to all available antibiotics. Phage therapy...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 601: A Novel Inducible Prophage from Burkholderia Vietnamiensis G4 is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia Viruses doi: 10.3390/v12060601 Authors: Weiser Yap Otter Jones Salvage Parkhill Mahenthiralingam Burkholderia species have environmental, industrial and medical significance, and are important opportunistic pathogens in individuals with cystic fibrosis (CF). Using a combination...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 600: Bovine Viral Diarrhea Virus: Recent Findings about Its Occurrence in Pigs Viruses doi: 10.3390/v12060600 Authors: Luís Guilherme de Oliveira Marina L. Mechler-Dreibi Henrique M. S. Almeida Igor R. H. Gatto Bovine viral diarrhea virus (BVDV) is an important pathogen belonging to the Pestivirus genus, Flaviviridae family, which comprises viral species that causes an economic impact in animal production. Cattle are the natural host of BVDV and the main...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 599: Porcine Epidemic Diarrhea Virus nsp15 Antagonizes Interferon Signaling by RNA Degradation of TBK1 and IRF3 Viruses doi: 10.3390/v12060599 Authors: Yang Wu Hongling Zhang Zhaorong Shi Jianfei Chen Mingwei Li Hongyan Shi Da Shi Longjun Guo Li Feng Porcine epidemic diarrhea virus (PEDV) causes a porcine disease associated with swine epidemic diarrhea. The type I interferon (IFN-I or IFN α/β) is a key mediator of innate...
Sun May 31, 2020 03:00
Viruses, Vol. 12, Pages 598: Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses Viruses doi: 10.3390/v12060598 Authors: Fernandes Freire Bueno Godoy Gil Oliva Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden....
Sat May 30, 2020 03:00
Viruses, Vol. 12, Pages 597: Antibody Neutralization of an Influenza Virus that Uses Neuraminidase for Receptor Binding Viruses doi: 10.3390/v12060597 Authors: Gentles Wan Eichelberger Bloom Influenza virus infection elicits antibodies against the receptor-binding protein hemagglutinin (HA) and the receptor-cleaving protein neuraminidase (NA). Because HA is essential for viral entry, antibodies targeting HA often potently neutralize the virus in single-cycle infection assays....
Sat May 30, 2020 03:00
Viruses, Vol. 12, Pages 596: SETDB1-Mediated Silencing of Retroelements Viruses doi: 10.3390/v12060596 Authors: Fukuda Shinkai SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) is a protein lysine methyltransferase and methylates histone H3 at lysine 9 (H3K9). Among other H3K9 methyltransferases, SETDB1 and SETDB1-mediated H3K9 trimethylation (H3K9me3) play pivotal roles for silencing of endogenous and exogenous retroelements, thus contributing to genome stability...
Sat May 30, 2020 03:00
Viruses, Vol. 12, Pages 595: Adenovirus 14p1 Immunopathogenesis during Lung Infection in the Syrian Hamster Viruses doi: 10.3390/v12060595 Authors: Jay R. Radke Hunter J. Covert Fredrick Bauer Vijayalakshmi Ananthanarayanan James L. Cook Adenovirus (Ad) infections are usually mild and self-limited, with minimal inflammatory responses. During worldwide outbreaks, Ad14p1, an emerging Ad14 variant, has caused severe pulmonary disease, including acute respiratory distress syndrome...
Sat May 30, 2020 03:00
Viruses, Vol. 12, Pages 594: Human Cytomegalovirus-Encoded G Protein-Coupled Receptor UL33 Facilitates Virus Dissemination via the Extracellular and Cell-to-Cell Route Viruses doi: 10.3390/v12060594 Authors: Jeffrey R. van Senten Maarten P. Bebelman Puck van Gasselt Nick D. Bergkamp Jelle van den Bor Marco Siderius Martine J. Smit Human cytomegalovirus (HCMV) encodes four G protein-coupled receptor (GPCR) homologs. Three of these receptors, UL78, US27 and US28, are...
Sat May 30, 2020 03:00
Viruses, Vol. 12, Pages 591: Age-Dependent Lethality in Ducks Caused by Highly Pathogenic H5N6 Avian Influenza Virus Viruses doi: 10.3390/v12060591 Authors: Yunyueng Jang Sang Heui Seo Ducks show notably higher resistance to highly pathogenic avian influenza viruses as compared to chickens. Here, we studied the age-dependent susceptibility in ducks to the infections caused by highly pathogenic avian influenza viruses. We intranasally infected ducks aged 1, 2, 4, and 8 weeks with highly...
Fri May 29, 2020 03:00
Viruses, Vol. 12, Pages 593: Natural History of Aerosol Induced Lassa Fever in Non‑Human Primates Viruses doi: 10.3390/v12060593 Authors: Isaac L. Downs Carl I. Shaia Xiankun Zeng Joshua C. Johnson Lisa Hensley David L. Saunders Franco Rossi Kathleen A. Cashman Heather L. Esham Melissa K. Gregory William D. Pratt John C. Trefry Kyle A. Everson Charles B. Larcom Arthur C. Okwesili Anthony P. Cardile Anna Honko Lassa virus (LASV), an arenavirus...
Fri May 29, 2020 03:00
Viruses, Vol. 12, Pages 592: Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes Viruses doi: 10.3390/v12060592 Authors: Lise Lauterbach-Rivière Maïwenn Bergez Saskia Mönch Bingqian Qu Maximilian Riess Florian W. R. Vondran Juliane Liese Veit Hornung Stephan Urban and Renate König Hepatitis B virus (HBV) chronic infection is a critical risk factor for hepatocellular carcinoma. The innate immune response to...
Fri May 29, 2020 03:00
Viruses, Vol. 12, Pages 590: Non-Mouse-Adapted H1N1pdm09 Virus as a Model for Influenza Research Viruses doi: 10.3390/v12060590 Authors: Irina Kiseleva Andrey Rekstin Mohammad Al Farroukh Ekaterina Bazhenova Anastasia Katelnikova Ludmila Puchkova Larisa Rudenko The number of lung-adapted influenza viruses is limited. Most of them are not antigenically related to current circulating viruses. Viruses similar to recent strains are required for screening modern antiviral...
Fri May 29, 2020 03:00
Water, Vol. 12, Pages 1578: Regional Inundation Forecasting Using Machine Learning Techniques with the Internet of Things Water doi: 10.3390/w12061578 Authors: Shun-Nien Yang Li-Chiu Chang Natural disasters have tended to increase and become more severe over the last decades. A preparation measure to cope with future floods is flood forecasting in each particular area for warning involved persons and resulting in the reduction of damage. Machine learning (ML) techniques have a great...
Sun May 31, 2020 03:00
Water, Vol. 12, Pages 1577: Quality of Dissolved Organic Matter Driven by Autotrophic and Heterotrophic Microbial Processes in a Large River Water doi: 10.3390/w12061577 Authors: Kamjunke Lechtenfeld Herzsprung Rivers are regarded as important sites for processing of dissolved organic matter (DOM) from terrestrial sources on its way to the ocean. However, little is known about the longitudinal change of DOM molecular composition in large rivers. Here we performed a Lagrangian...
Sun May 31, 2020 03:00
Water, Vol. 12, Pages 1575: Highly Saline Water Desalination Using Direct Contact Membrane Distillation (DCMD): Experimental and Simulation Study Water doi: 10.3390/w12061575 Authors: Ameen Ibrahim Alsalhy Figoli The path for water molecules transported across a membrane in real porous membranes has been considered to be a constant factor in the membrane distillation (MD) process (i.e., constant tortuosity); as such, its effect on membrane performance at various operating...
Sun May 31, 2020 03:00
Water, Vol. 12, Pages 1574: Mercury, Arsenic and Lead Removal by Air Gap Membrane Distillation: Experimental Study Water doi: 10.3390/w12061574 Authors: Abdullah Alkhudhiri Mohammed Hakami Myrto-Panagiota Zacharof Hosam Abu Homod Ahmed Alsadun Synthetic industrial wastewater samples containing mercury (Hg), arsenic (As), and lead (Pb) ions in various concentrations were prepared and treated by air gap membrane distillation (AGMD), a promising method for heavy metals removal....
Sun May 31, 2020 03:00
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