Related ArticlesEffectiveness of Adenotonsillectomy vs Watchful Waiting in Young Children With Mild to Moderate Obstructive Sleep Apnea: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2020 May 28;: Authors: Fehrm J, Nerfeldt P, Browaldh N, Friberg D Abstract Importance: Adenotonsillectomy (ATE) is one of the most common surgical procedures to treat children with obstructive sleep apnea (OSA), but to our knowledge there are no randomized...
Fri May 29, 2020 13:11
Related Articles[Obesity and risk of severe COVID-19]. Rev Med Suisse. 2020 May 27;16(695):1115-1119 Authors: Scheen AJ Abstract Obesity represents a higher risk of severe COVID-19 infection, which may lead to the requirement of a mechanical ventilation in intensive care units and premature death. The underlying mechanisms are multiple: alteration of the respiratory performance, presence of comorbidities such as diabetes, hypertension or obstructive...
Fri May 29, 2020 13:11
Related ArticlesInsurance-Mandated Medical Weight Management Programs in Sleeve Gastrectomy Patients Do Not Improve Postoperative Weight Loss Outcomes at 1 Year. Obes Surg. 2020 May 27;: Authors: Talishinskiy T, Blatt M, Nyirenda T, Eid S, Schmidt H, Ewing D Abstract BACKGROUND/INTRODUCTION: Qualification for bariatric surgery is based upon strict medical guidelines, but individual insurance companies may introduce additional requirements for approval...
Fri May 29, 2020 13:11
Publication date: Available online 30 May 2020Source: Sleep MedicineAuthor(s): S.M. Romanella, D. Roe, E. Tatti, D. Cappon, R. Paciorek, E. Testani, A. Rossi, S. Rossi, E. Santarnecchi
Sun May 31, 2020 13:36
Publication date: Available online 29 May 2020Source: Sleep MedicineAuthor(s): Fuquan Shi, Chang Liu, Kun Liu, Lei Sun, Huan Yang, Jia Cao, Qing Chen
Fri May 29, 2020 19:58
Related ArticlesPharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research. Thromb Haemost. 2020 May 30;: Authors: Bikdeli B, Madhavan MV, Gupta A, Jimenez D, Burton JR, Der Nigoghossian C, Chuich T, Nouri SN, Dreyfus I, Driggin E, Sethi S, Sehgal K, Chatterjee S, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Bertoletti L, Giri J, Cushman M, Quéré I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Tafur AJ, Francese...
Sun May 31, 2020 15:09
Related ArticlesChallenges in early phase clinical trials for childhood cancer during the COVID-19 pandemic: a report from the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP). Clin Transl Oncol. 2020 May 29;: Authors: Rubio-San-Simón A, Verdú-Amorós J, Hladun R, Juan-Ribelles A, Molero M, Guerra-García P, Pérez-Martínez A, Castañeda A, Cañete A, de Rojas T, Moreno L, Bautista F Abstract PURPOSE: The COVID-19 pandemic...
Sun May 31, 2020 13:35
Related ArticlesComputational Tools for the Reliability Assessment and the Engineering Design of Procedures and Devices in Bariatric Surgery. Ann Biomed Eng. 2020 May 29;: Authors: Salmaso C, Toniolo I, Fontanella CG, Da Roit P, Albanese A, Polese L, Stefanini C, Foletto M, Carniel EL Abstract Obesity is one of the main health concerns worldwide. Bariatric Surgery (BS) is the gold standard treatment for severe obesity. Nevertheless, unsatisfactory weight...
Sun May 31, 2020 13:35
Related ArticlesRisk Assessment and Considerations for Proper Management of Elderly Men with Advanced Prostate Cancer: A Systematic Review. Eur Urol Oncol. 2020 May 26;: Authors: Shevach JW, Weiner AB, Kasimer RN, Miller CH, Morgans AK Abstract CONTEXT: Treatment decisions for elderly men with prostate cancer are complicated by the intersection of competing risks of cancer, potential complications of treatment, and individual patients' comorbidities....
Sun May 31, 2020 13:35
Related ArticlesGeriatric assessment and quality of life changes in older adults with newly diagnosed multiple myeloma undergoing treatment. J Geriatr Oncol. 2020 May 26;: Authors: Mian H, Pond GR, Tuchman SA, Fiala MA, Wildes TM Abstract OBJECTIVE: Multiple myeloma (MM) is a cancer of older adults with a median age at diagnosis of 70 years. Our study aimed to understand the changes that occurred in geriatric domains and quality of life parameters as...
Sun May 31, 2020 13:35
Related ArticlesMR-guided proton therapy: a review and a preview. Radiat Oncol. 2020 May 29;15(1):129 Authors: Hoffmann A, Oborn B, Moteabbed M, Yan S, Bortfeld T, Knopf A, Fuchs H, Georg D, Seco J, Spadea MF, Jäkel O, Kurz C, Parodi K Abstract BACKGROUND: The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The integration of MRI and PT at...
Sun May 31, 2020 13:35
Related ArticlesExercise Oncology and Immuno-Oncology; A (Future) Dynamic Duo. Int J Mol Sci. 2020 May 27;21(11): Authors: Holmen Olofsson G, Jensen AWP, Idorn M, Thor Straten P Abstract Recent advances in clinical oncology is based on exploiting the capacity of the immune system to combat cancer: immuno-oncology. Thus, immunotherapy of cancer is now used to treat a variety of malignant diseases. A striking feature is that even patients with late-stage...
Sun May 31, 2020 13:35
Related ArticlesCaregiver-provider communication after resection of pediatric brain tumors. J Neurosurg Pediatr. 2020 May 29;:1-7 Authors: Cutillo A, Zimmerman K, Davies S, Madan-Swain A, Landier W, Arynchyna A, Rocque BG Abstract OBJECTIVE: Because caregivers are a crucial part of a child's medical care, it is important to understand how to best communicate with them during hospitalization. Qualitative research can elucidate the best strategies for...
Sat May 30, 2020 15:02
Related ArticlesPediatric vestibular schwannomas: case series and a systematic review with meta-analysis. J Neurosurg Pediatr. 2020 May 29;:1-9 Authors: Malina GEK, Heiferman DM, Riedy LN, Szujewski CC, Rezaii EG, Leonetti JP, Anderson DE Abstract OBJECTIVE: Sporadic unilateral vestibular schwannomas are rare in the pediatric population. Little has been reported in the literature on the presentation, tumor size, response to surgical treatment, and recurrence...
Sat May 30, 2020 15:02
Related ArticlesEncorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer. Transl Oncol. 2020 May 26;13(9):100795 Authors: Roviello G, D'Angelo A, Petrioli R, Roviello F, Cianchi F, Nobili S, Mini E, Lavacchi D Abstract BRAFV600-mutated colorectal cancer (CRC) accounts for 8% to 12% of all CRC diagnoses. These tumors are often associated with specific patient features, including right-sided primary tumor location, peritoneal and...
Sat May 30, 2020 15:02
Related ArticlesCardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib. Int J Cardiol. 2020 May 26;: Authors: Singh AP, Umbarkar P, Tousif S, Lal H Abstract The advent of tyrosine kinase inhibitors (TKIs) targeted therapy revolutionized the treatment of chronic myeloid leukemia (CML) patients. However, cardiotoxicity associated with these targeted therapies puts the cancer survivors at higher risk. Ponatinib is a third-generation...
Sat May 30, 2020 15:02
Related ArticlesGlobal publications on stigma between 1998-2018: A bibliometric analysis. J Affect Disord. 2020 May 11;274:363-371 Authors: Chen S, Lu Q, Bai J, Deng C, Wang Y, Zhao Y Abstract OBJECTIVES: To describe the development process and structural relationships of scientific achievements on stigma over the past two decades and to provide insights for researchers and policy makers to drive policy decisions and identify future research needs. ...
Sat May 30, 2020 15:02
Related ArticlesHighlights of the San Antonio Breast Cancer Symposium 2019 Part 2: the challenges of tumor heterogeneity. Future Oncol. 2020 May 29;: Authors: Benson JR, Dumitru D, Jatoi I PMID: 32469673 [PubMed - as supplied by publisher]
Sat May 30, 2020 15:02
Related ArticlesReal-world outcomes of radium-223 dichloride for metastatic castration resistant prostate cancer. Future Oncol. 2020 May 29;: Authors: Kuppen MC, Westgeest HM, van der Doelen MJ, van den Eertwegh AJ, Coenen JL, Aben KK, van den Bergh AC, Bergman AM, den Bosch JV, Celik F, Hendriks MP, Lavalaye J, der Meer SV, Polee MB, Somford DM, van Oort IM, Uyl-de Groot CA, Gerritsen WR Abstract Aim: Timing of radium-223 (Ra-223) in metastatic castration-resistant...
Sat May 30, 2020 15:02
Related ArticlesHighlights of the San Antonio Breast Cancer Symposium 2019 Part 1: the challenges of tumor heterogeneity. Future Oncol. 2020 May 29;: Authors: Benson JR, Dumitru D, Jatoi I PMID: 32469603 [PubMed - as supplied by publisher]
Sat May 30, 2020 15:02
Related ArticlesWhat Is the 10-year Survivorship of Cemented Distal Femoral Endoprostheses for Tumor Reconstructions and What Radiographic Features Are Associated with Survival? Clin Orthop Relat Res. 2020 May 26;: Authors: Piakong P, Kiatisevi P, Yau R, Trovarelli G, Lam YL, Joyce D, Ruggieri P, Temple HT, Letson D, Binitie O Abstract BACKGROUND: Aseptic loosening is one of the most common causes of revision of distal femoral endoprostheses and is considered...
Sat May 30, 2020 15:02
Related ArticlesmiR-146a promotes proliferation, invasion, and epithelial-to-mesenchymal transition in oral squamous carcinoma cells. Environ Toxicol. 2020 May 29;: Authors: Wang F, Ye LJ, Wang FJ, Liu HF, Wang XL Abstract Epithelial-to-mesenchymal transition (EMT) is key to invasion and metastasis by oral squamous carcinoma (OSCC) cells. MicroRNAs (miRNAs) such as miRNA-146a are known to be upregulated in OSCC. However, it is unclear whether they are...
Sat May 30, 2020 15:02
Related ArticlesAssessment of Patient and Caregiver Attitudes and Approaches to Decision-Making Regarding Bone Marrow Transplant for Sickle Cell Disease: A Qualitative Study. JAMA Netw Open. 2020 May 01;3(5):e206742 Authors: Bakshi N, Katoch D, Sinha CB, Ross D, Quarmyne MO, Loewenstein G, Krishnamurti L Abstract Importance: Bone marrow transplant (BMT) is a potentially curative treatment for sickle cell disease (SCD). Patient and caregiver attitudes...
Sat May 30, 2020 15:02
Related ArticlesThe future of cancer research after COVID-19 pandemic: recession? Future Oncol. 2020 May 29;: Authors: Kourie HR, Eid R, Haddad F, Ghosn M, Sarkis DK PMID: 32469283 [PubMed - as supplied by publisher]
Sat May 30, 2020 15:02
Related ArticlesFacing SARS-CoV-2 outbreak in immunotherapy era. Future Oncol. 2020 May 29;: Authors: Citarella F, Russano M, Pantano F, Dell'Aquila E, Vincenzi B, Tonini G, Santini D Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread represents a sanitary emergency all over the world. Viral biology is only partially known with some aspects in common with other CoV and the damage observed in most severe cases is due to intense...
Sat May 30, 2020 15:02
Related ArticlesAmenorrhea After Chemotherapy In Breast Cancer Patient. J Ayub Med Coll Abbottabad. 2020 Jan- Mar;32(1):73-77 Authors: Ravi R, Haider G, Ahmed K, Sami A, Zahoor S, Lata R Abstract BACKGROUND: This study was conducted to determine the frequency of amenorrhea after chemotherapy among breast cancer patients". METHODS: Total 201 premenopausal females (having menstruation during the past 6 months at the time of diagnosis) of age 15-45...
Sat May 30, 2020 13:24
Related ArticlesBK channel subunits promote breast cancer development and modulate endocrine treatment response in pre-clinical models. Br J Pharmacol. 2020 May 28;: Authors: Mohr CJ, Schroth W, Mürdter TE, Gross D, Maier S, Stegen B, Dragoi A, Steudel FA, Stehling S, Hoppe R, Madden S, Ruth P, Huber SM, Brauch H, Lukowski R Abstract BACKGROUND AND PURPOSE: Pore-forming α subunits of the voltage- and Ca2+ -activated K+ channel of big conductance (BKα)...
Sat May 30, 2020 13:24
Related ArticlesRisk factors of impairment of shoulder function after axillary dissection for breast cancer. Support Care Cancer. 2020 May 28;: Authors: Kikuuchi M, Akezaki Y, Nakata E, Yamashita N, Tominaga R, Kurokawa H, Hamada M, Aogi K, Ohsumi S, Tsuji T, Sugihara S Abstract OBJECTIVES: Postoperative shoulder joint dysfunction has been observed at a certain rate after breast cancer surgery with axillary lymph node dissection. The purposes of this...
Sat May 30, 2020 13:24
Related Articles[Immunotherapy in bladder cancer-quo vadis? Update on current trials and developments]. Urologe A. 2020 May 28;: Authors: Todenhöfer T, Boegemann M Abstract BACKGROUND: Great advances have been made for the treatment of urothelial carcinoma by the introduction of checkpoint inhibitors (CPI). Single-agent immunotherapy with CPIs has been approved for patients with metastatic or locally advanced inoperable urothelial carcinoma who have...
Sat May 30, 2020 13:24
Related ArticlesArtificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care (Review). Int J Oncol. 2020 May 11;: Authors: Trivizakis E, Papadakis GZ, Souglakos I, Papanikolaou N, Koumakis L, Spandidos DA, Tsatsakis A, Karantanas AH, Marias K Abstract The new era of artificial intelligence (AI) has introduced revolutionary data‑driven analysis paradigms that have led to significant advancements in information processing...
Sat May 30, 2020 13:24
Related ArticlesN-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity. Cancer Cell Int. 2020;20:170 Authors: Keenan B, Finol-Urdaneta RK, Hope A, Bremner JB, Kavallaris M, Lucena-Agell D, Oliva MÁ, Díaz JF, Vine KL Abstract Background: Drug resistance and chemotherapy-induced peripheral neuropathy continue to be...
Sat May 30, 2020 13:24
Related ArticlesThe future of cancer immunotherapy: microenvironment-targeting combinations. Cell Res. 2020 May 28;: Authors: Murciano-Goroff YR, Warner AB, Wolchok JD Abstract Immunotherapy holds the potential to induce durable responses, but only a minority of patients currently respond. The etiologies of primary and secondary resistance to immunotherapy are multifaceted, deriving not only from tumor intrinsic factors, but also from the complex interplay...
Sat May 30, 2020 13:24
Related ArticlesWJOG10517G: a multicenter Phase II study of mFOLFOX6 in gastric cancer patients with severe peritoneal metastases. Future Oncol. 2020 May 29;: Authors: Masuishi T, Nakajima TE, Yamazaki K, Hironaka S, Kudo C, Yoshimura K, Muro K Abstract Gastric cancer patients with severe peritoneal metastases, defined as massive ascites and/or inadequate oral intake, have been excluded from clinical trials of new treatments due to poor prognosis and...
Sat May 30, 2020 13:24
Related ArticlesRisk of Hepatocellular Carcinoma after HCV Clearance by Direct-Acting Antivirals Treatment Predictive Factors and Role of Epigenetics. Cancers (Basel). 2020 May 26;12(6): Authors: Rinaldi L, Nevola R, Franci G, Perrella A, Corvino G, Marrone A, Berretta M, Morone MV, Galdiero M, Giordano M, Adinolfi LE, Sasso FC Abstract Direct-acting antivirals (DAAs) induce a rapid virologic response (SVR) in up to 99% of chronic hepatitis C patients....
Sat May 30, 2020 13:24
Related ArticlesGenomic and Transcriptomic Characteristics According to Size of Papillary Thyroid Microcarcinoma. Cancers (Basel). 2020 May 25;12(5): Authors: Song YS, Kang BH, Lee S, Yoo SK, Choi YS, Park J, Park DY, Lee KE, Seo JS, Park YJ Abstract It is controversial as to whether papillary thyroid microcarcinoma (PTMC) has some genomic and transcriptomic characteristics that differentiate between an early-stage lesion that would eventually evolve...
Sat May 30, 2020 13:24
Related ArticlesHope in Medicine: Applying Multidisciplinary Insights. Perspect Biol Med. 2019;62(4):591-616 Authors: Kube T, Blease C, Ballou SK, Kaptchuk TJ Abstract Hope is a crucial aspect of human life and has been a topic of interest in many scholarly disciplines. The medical literature, however, has-with a few exceptions-failed to take account of conceptions of hope across other scholarly disciplines. Before exploring what makes hope a distinctive...
Sat May 30, 2020 13:24
Related ArticlesFucosylation Enhances the Efficacy of Adoptively Transferred Antigen-Specific Cytotoxic T Lymphocytes. Clin Cancer Res. 2019 04 15;25(8):2610-2620 Authors: Alatrash G, Qiao N, Zhang M, Zope M, Perakis AA, Sukhumalchandra P, Philips AV, Garber HR, Kerros C, St John LS, Khouri MR, Khong H, Clise-Dwyer K, Miller LP, Wolpe S, Overwijk WW, Molldrem JJ, Ma Q, Shpall EJ, Mittendorf EA Abstract PURPOSE: Inefficient homing of adoptively transferred...
Sat May 30, 2020 13:24
Related ArticlesThe role of metabolic diseases in cardiotoxicity associated with cancer therapy: What we know, what we would know. Life Sci. 2020 May 25;:117843 Authors: L'Abbate S, Russo I, Kusmic C Abstract Metabolic diseases, such as obesity and type 2 diabetes, is known risk factor for cardiovascular (CV) diseases. Thus, patients with those comorbidities could be at increased risk of experiencing cardiotoxicity related to treatment with Anthracyclines...
Fri May 29, 2020 14:30
Related ArticlesDefining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases. ACS Chem Neurosci. 2020 May 28;: Authors: Krahn AI, Wells C, Drewry DH, Beitel LK, Durcan TM, Axtman AD Abstract Kinases are highly tractable drug targets that have reached unparalleled success in fields such as cancer but whose potential has not yet been realized in neuroscience. There are currently 55 approved...
Fri May 29, 2020 14:30
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