Related ArticlesPrevalence of smoking, quit attempts and access to cessation treatment among adults with mental illness in Brazil: a cross-sectional analysis of a National Health Survey. BMJ Open. 2020 May 26;10(5):e033959 Authors: Cruvinel E, Liebman E, Leite I, Hu J, Richter KP Abstract OBJECTIVES: Determine the national prevalence of smoking and factors related to smoking among adults with mental illness (PLWMI; people living with mental illness)...
Fri May 29, 2020 15:15
Related ArticlesRetrospective cohort study to characterise the blood pressure response to spironolactone in patients with apparent therapy-resistant hypertension using electronic medical record data. BMJ Open. 2020 May 26;10(5):e033100 Authors: Shuey M, Perkins B, Nian H, Yu C, Luther JM, Brown N Abstract OBJECTIVE: Identify blood pressure (BP) response to spironolactone in patients with apparent therapy-resistant hypertension (aTRH) using electronic...
Fri May 29, 2020 15:15
Related ArticlesCohort profile: the Australian genetics of depression study. BMJ Open. 2020 May 26;10(5):e032580 Authors: Byrne EM, Kirk KM, Medland SE, McGrath JJ, Colodro-Conde L, Parker R, Cross S, Sullivan L, Statham DJ, Levinson DF, Licinio J, Wray NR, Hickie IB, Martin NG Abstract PURPOSE: Depression is the most common psychiatric disorder and the largest contributor to global disability. The Australian Genetics of Depression study was established...
Fri May 29, 2020 15:15
Related ArticlesPneumoperitoneum preconditioning for the prevention of renal function after laparoscopic partial nephrectomy: protocol for a double-blind randomised controlled trial. BMJ Open. 2020 May 26;10(5):e032002 Authors: Zhou C, Xu L, Xu Z, Ge Y, Zhou L, Wang F, Liu J, Pan G, Yang T, Jia R Abstract INTRODUCTION: Renal ischaemia reperfusion injury is an inevitable pathophysiology in different clinical situations including laparoscopic partial nephrectomy...
Fri May 29, 2020 15:15
Related ArticlesEverestmab, a novel long-acting GLP-1/anti GLP-1R nanobody fusion protein, exerts potent anti-diabetic effects. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):854-866 Authors: Pan H, Su Y, Xie Y, Wang W, Qiu W, Chen W, Lu W, Lu Z, Wang W, Shang A Abstract In the present study, a novel single domain antibody (sdAb) fusion protein, named everestmab, composing of a mutated GLP-1(A8G) fused to the tandem bispecific humanized GLP-1R-targeting...
Sat May 30, 2020 14:54
Related ArticlesA systematic review and meta-analysis of long noncoding RNA linc-UBC1 expression and prognosis and clinicopathological phenotypes in human cancers. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):875-884 Authors: Zhang X, Xie H, Luo M, Liang D, Lao W, Ma W, Lin Y Abstract According to previous studies, linc-UBC1 is abnormally expressed in various human tumours. Nonetheless, the clinical significance and mechanism of linc-UBC1 in cancer...
Fri May 29, 2020 14:57
Related ArticlesThe P50 value detected by the oxygenation-dissociation analyser and blood gas analyser. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):867-874 Authors: Chu Z, Wang Y, You G, Wang Q, Ma N, Li B, Zhao L, Zhou H Abstract Oxygen tension at 50% haemoglobin saturation (P50), which reflects the degree of peripheral oxygen offloading and tissue oxygenation, plays an important role in the diagnosis and treatment of disease, as well as in transfusion...
Fri May 29, 2020 14:57
Long-acting injectable luteinizing hormone–releasing hormone (LHRH) agonists are commonly used as androgen-deprivation therapy to achieve castrate levels of testosterone in the treatment of advanced prostate cancer. LHRH agonists cause an initial testosterone surge that may result in a clinical…
Fri May 29, 2020 03:00
Cardiovascular disease is the leading cause of death in men in the United States and in the developed world. Men with prostate cancer have a higher incidence of cardiovascular disease than those without, and among men with prostate cancer, cardiovascular disease is the principal non–cancer-related…
Fri May 29, 2020 03:00
An estimated 15 to 20% of advanced gastric and gastroesophageal junction cancers, which are especially prevalent in East Asia, have overexpression or amplification of human epidermal growth factor receptor 2 (HER2). Chemotherapy plus the anti-HER2 antibody trastuzumab is the recommended first-line…
Fri May 29, 2020 03:00
Enzalutamide, an oral androgen-receptor inhibitor, in combination with androgen-deprivation therapy was approved by the Food and Drug Administration to treat nonmetastatic, castration-resistant prostate cancer in 2018 on the basis of a significantly lower risk of metastasis or death without…
Fri May 29, 2020 03:00
Related ArticlesProbing the circuits of conscious perception with magnetophosphenes. J Neural Eng. 2020 May 29;: Authors: Modolo J, Hassan M, Ruffini G, Legros A Abstract BACKGROUND: Conscious perception is thought to involve the large-scale, coordinated activation of distant brain regions, a process termed ignition in the Global Workspace Theory and integration in Integrated Information Theory, which are two of the major theories of consciousness. ...
Sat May 30, 2020 14:42
Related Articles[Organ preservation in advanced laryngeal/hypopharyngeal carcinoma: lessons from the DeLOS-II trial]. HNO. 2020 May 28;: Authors: Dietz A, Wichmann G, Kuhnt T, Wiegand S Abstract Patients with locoregionally advanced laryngeal and hypopharyngeal squamous cell carcinomas (LHSCC) comprise two broad groups: those who are candidates for functional larynx preservation (LP) with avoidance of ablative surgery and those who are not. Currently,...
Sat May 30, 2020 14:32
Abstract Purpose To assess the methodological quality of published systematic reviews relating to all ceramic implant frameworks, abutments and restorations. Materials and Methods Published systematic reviews relating to all ceramic implant restorations for single tooth and multiple teeth replacements were retrieved to assess their methodological qualities. Sixteen systematic reviews were included for methodological quality assessment by two independent assessors using AMSTAR‐2 critical...
Sat May 30, 2020 13:33
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 15:06
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 15:06
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 15:00
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 15:00
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 07:05
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri May 29, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Thu May 28, 2020 11:41
The MET proto-oncogene encodes a receptor tyrosine kinase, and binding to its ligand (hepatocyte growth factor [HGF]) induces downstream signaling through the RAS–RAF and phosphoinositide 3-kinase (PI3K) pathways. Aberrant MET signaling drives tumor growth through increased cell proliferation,…
Fri May 29, 2020 03:00
Related ArticlesThe wriggly resilience of eels to angler catch-and-release. Conserv Physiol. 2020;8(1):coaa050 Authors: Killacky MS PMID: 32467759 [PubMed]
Sat May 30, 2020 14:12
Related ArticlesEffects of ultraviolet-B radiation on physiology, immune function and survival is dependent on temperature: implications for amphibian declines. Conserv Physiol. 2020;8(1):coaa002 Authors: Lundsgaard NU, Cramp RL, Franklin CE, Martin L Abstract Multiple environmental changes are thought to be contributing to the widespread decline of amphibians in montane regions, but interactions between drivers of decline are not well understood. It...
Sat May 30, 2020 14:12
Related ArticlesSeasonal and daily variations in primary and secondary metabolism of three maquis shrubs unveil different adaptive responses to Mediterranean climate. Conserv Physiol. 2019;7(1):coz070 Authors: Gori A, Tattini M, Centritto M, Ferrini F, Marino G, Mori J, Guidi L, Brunetti C Abstract Maquis species play a central role in the maintenance of coastal ecosystems thanks to anatomical, physiological and biochemical features evolved to cope with...
Sat May 30, 2020 14:12
Abstract Diagnostic imaging of pediatric gastric masses often provides a challenge for the practicing radiologist. Radiologists should be aware of this relatively unusual pathology, particularly in cross-sectional imaging findings. We will review pediatric gastric masses and mass-like lesions, focusing on neoplastic and inflammatory etiologies.
Sat May 30, 2020 03:00
Abstract There is a broad spectrum of congenital anomalies of the central pulmonary arteries including abnormalities of development, origin, course and caliber. These anomalies incorporate simple lesions such as isolated pulmonary valve stenosis to very complex anomalies with many associated abnormalities. Part 1 and Part 2 of this review describe the range of anatomical variations that are encountered as well as important aspects of anatomy, physiology and surgical correction....
Sat May 30, 2020 03:00
Sat May 30, 2020 03:00
Abstract Background Burnout in medicine, and specifically radiology, has been receiving more attention. Little data-driven literature is available regarding risk factors/causes to ultimately help guide the development of potential solutions. Objective To survey pediatric radiologists, a cohort with a documented high prevalence of burnout, and to understand...
Sat May 30, 2020 03:00
Related ArticlesHighlights of the San Antonio Breast Cancer Symposium 2019 Part 2: the challenges of tumor heterogeneity. Future Oncol. 2020 May 29;: Authors: Benson JR, Dumitru D, Jatoi I PMID: 32469673 [PubMed - as supplied by publisher]
Sat May 30, 2020 18:03
Related ArticlesReal-world outcomes of radium-223 dichloride for metastatic castration resistant prostate cancer. Future Oncol. 2020 May 29;: Authors: Kuppen MC, Westgeest HM, van der Doelen MJ, van den Eertwegh AJ, Coenen JL, Aben KK, van den Bergh AC, Bergman AM, den Bosch JV, Celik F, Hendriks MP, Lavalaye J, der Meer SV, Polee MB, Somford DM, van Oort IM, Uyl-de Groot CA, Gerritsen WR Abstract Aim: Timing of radium-223 (Ra-223) in metastatic castration-resistant...
Sat May 30, 2020 18:03
Related ArticlesHighlights of the San Antonio Breast Cancer Symposium 2019 Part 1: the challenges of tumor heterogeneity. Future Oncol. 2020 May 29;: Authors: Benson JR, Dumitru D, Jatoi I PMID: 32469603 [PubMed - as supplied by publisher]
Sat May 30, 2020 18:03
Related ArticlesThe future of cancer research after COVID-19 pandemic: recession? Future Oncol. 2020 May 29;: Authors: Kourie HR, Eid R, Haddad F, Ghosn M, Sarkis DK PMID: 32469283 [PubMed - as supplied by publisher]
Sat May 30, 2020 18:03
Related ArticlesFacing SARS-CoV-2 outbreak in immunotherapy era. Future Oncol. 2020 May 29;: Authors: Citarella F, Russano M, Pantano F, Dell'Aquila E, Vincenzi B, Tonini G, Santini D Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread represents a sanitary emergency all over the world. Viral biology is only partially known with some aspects in common with other CoV and the damage observed in most severe cases is due to intense...
Sat May 30, 2020 18:03
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