Antibiotics, Vol. 9, Pages 294: Satureja montana L. and Origanum majorana L. Decoctions: Antimicrobial Activity, Mode of Action and Phenolic Characterization Antibiotics doi: 10.3390/antibiotics9060294 Authors: Fernanda Gomes Maria Inês Dias Ângela Lima Lillian Barros Maria Elisa Rodrigues Isabel C.F.R. Ferreira Mariana Henriques Medicinal and aromatic plants are known to have a wide range of uses and health benefits, and should be exploited for their bioactivity. Here...
Sun May 31, 2020 03:00
Antibiotics, Vol. 9, Pages 293: The Puzzle of Coccoid Forms of Helicobacter pylori: Beyond Basic Science Antibiotics doi: 10.3390/antibiotics9060293 Authors: Enzo Ierardi Giuseppe Losurdo Alessia Mileti Rosa Paolillo Floriana Giorgio Mariabeatrice Principi Alfredo Di Leo Helicobacter pylori (H. pylori) may enter a non-replicative, non-culturable, low metabolically active state, the so-called coccoid form, to survive in extreme environmental conditions. Since coccoid...
Sun May 31, 2020 03:00
Antibiotics, Vol. 9, Pages 292: New Synthetic Nitro-Pyrrolomycins as Promising Antibacterial and Anticancer Agents Antibiotics doi: 10.3390/antibiotics9060292 Authors: Raimondi Presentato Li Petri Buttacavoli Ribaudo De Caro Alduina Cancemi : Pyrrolomycins (PMs) are polyhalogenated antibiotics known as powerful biologically active compounds, yet featuring high cytotoxicity. The present study reports the antibacterial and antitumoral properties of new chemically...
Sat May 30, 2020 03:00
Antibiotics, Vol. 9, Pages 291: Adapting a Phage to Combat Phage Resistance Antibiotics doi: 10.3390/antibiotics9060291 Authors: Laanto Mäkelä Hoikkala Ravantti Sundberg Phage therapy is becoming a widely recognized alternative for fighting pathogenic bacteria due to increasing antibiotic resistance problems. However, one of the common concerns related to the use of phages is the evolution of bacterial resistance against the phages, putatively disabling the treatment....
Fri May 29, 2020 03:00
Antibodies, Vol. 9, Pages 20: Study of Neuraminidase-Inhibiting Antibodies in Clinical Trials of Live Influenza Vaccines Antibodies doi: 10.3390/antib9020020 Authors: Yulia Desheva Tatiana Smolonogina Svetlana Donina Larisa Rudenko Background: Currently, the immunogenicity of influenza vaccines is assessed by detecting an increase of hemagglutination inhibition (HI) antibodies. As neuraminidase (NA)-based immunity may be significant in protecting against influenza infection,...
Fri May 29, 2020 03:00
Antioxidants, Vol. 9, Pages 462: Comment on “Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis, Antioxidants 2020, 9(3), 195” Antioxidants doi: 10.3390/antiox9060462 Authors: Hegarty Byrne Minter, B.E. et al. recently published an article titled “Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative...
Fri May 29, 2020 03:00
Antioxidants, Vol. 9, Pages 463: Review of Structural Features and Binding Capacity of Polyphenols to Gluten Proteins and Peptides In Vitro: Relevance to Celiac Disease Antioxidants doi: 10.3390/antiox9060463 Authors: Miguel Ribeiro Telma de Sousa Patrícia Poeta Ana Sofia Bagulho Gilberto Igrejas Polyphenols have been extensively studied due to their beneficial effects on human health, particularly for the prevention and treatment of diseases related to oxidative stress....
Fri May 29, 2020 03:00
Arts, Vol. 9, Pages 66: How to Dismantle a [Theatric] Bomb: Broadway Flops, Broadway Money, and Musical Theater Historiography Arts doi: 10.3390/arts9020066 Authors: Wollman The Broadway musical, balancing as it does artistic expression and commerce, is regularly said to reflect its sociocultural surroundings. Its historiography, however, tends for the most part to emphasize art over commerce, and exceptional productions over all else. Broadway histories tend to prioritize the most...
Fri May 29, 2020 03:00
Atmosphere, Vol. 11, Pages 571: Assessment of Regional Climate Model Simulations of the Katabatic Boundary Layer Structure over Greenland Atmosphere doi: 10.3390/atmos11060571 Authors: Günther Heinemann The parameterization of the boundary layer is a challenge for regional climate models of the Arctic. In particular, the stable boundary layer (SBL) over Greenland, being the main driver for substantial katabatic winds over the slopes, is simulated differently by different regional climate...
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Atmosphere, Vol. 11, Pages 570: Spatial-Temporal Pattern of Black Carbon (BC) Emission from Biomass Burning and Anthropogenic Sources in New South Wales and the Greater Metropolitan Region of Sydney, Australia Atmosphere doi: 10.3390/atmos11060570 Authors: Duc Shingles White Salter Chang Gunashanhar Riley Trieu Dutt Azzi Beyer Hynes Kirkwood : Biomass burnings either due to Hazards Reduction Burnings (HRBs) in late autumn and early winter...
Sun May 31, 2020 03:00
Atmosphere, Vol. 11, Pages 569: Strong Spatiotemporal Radar Echo Nowcasting Combining 3DCNN and Bi-Directional Convolutional LSTM Atmosphere doi: 10.3390/atmos11060569 Authors: Suting Chen Song Zhang Huantong Geng Yaodeng Chen Chuang Zhang Jinzhong Min In order to solve the existing problems of easy spatiotemporal information loss and low forecast accuracy in traditional radar echo nowcasting, this paper proposes an encoding-forecasting model (3DCNN-BCLSTM) combining 3DCNN...
Fri May 29, 2020 03:00
Atmosphere, Vol. 11, Pages 565: High Resolution Chemistry Transport Modeling with the On-Line CHIMERE-WRF Model over the French Alps—Analysis of a Feedback of Surface Particulate Matter Concentrations on Mountainous Meteorology Atmosphere doi: 10.3390/atmos11060565 Authors: Bertrand Bessagnet Laurent Menut Rémy Lapere Florian Couvidat Jean-Luc Jaffrezo Sylvain Mailler Olivier Favez Romain Pennel Guillaume Siour Air pollution is of major concern throughout the...
Fri May 29, 2020 03:00
Atmosphere, Vol. 11, Pages 568: The Impact of Kelvin Wave Activity during Dry and Wet African Summer Rainfall Years Atmosphere doi: 10.3390/atmos11060568 Authors: Ademe Mekonnen Carl J. Schreck Bantwale D. Enyew This study highlights the influence of convectively coupled Kelvin wave (KW) activity on deep convection and African easterly waves (AEWs) over North Africa during dry and wet boreal summer rainfall years. Composite analysis based on 25 years of rainfall, satellite observed...
Fri May 29, 2020 03:00
Atmosphere, Vol. 11, Pages 567: Sensitivity of Volcanic Ash Dispersion Modelling to Input Grain Size Distribution Based on Hydromagmatic and Magmatic Deposits Atmosphere doi: 10.3390/atmos11060567 Authors: Osman Beckett Rust Snee The size distribution of volcanic ash is rarely measured in real time and Volcanic Ash Advisory Centres (VAACs) often rely on a default particle size distribution (PSD) to initialise their dispersion models when forecasting the movement of ash clouds....
Fri May 29, 2020 03:00
Atmosphere, Vol. 11, Pages 566: Conditions for a Meaningful Health Impact Assessment for Local Stakeholders: The Example of the Arve Valley in France Atmosphere doi: 10.3390/atmos11060566 Authors: Pascal Yvon Corso Blanchard De Crouy-Chanel Medina This article illustrates how a health impact assessment (HIA) can be used to promote a collaborative discussion among stakeholders as part of a local action plan aimed at improving air quality. We performed a HIA of the...
Fri May 29, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 96: Teachers’ Constructivist and Ethical Beliefs Behavioral Sciences doi: 10.3390/bs10060096 Authors: Marie Sharkey Hugh Gash Teachers’ approaches and beliefs are key determinants of teachers’ practice. This study was designed to examine whether two aspects of Irish primary teacher beliefs are associated, their views on constructivist practices and their views on two ethical dimensions (idealism and relativism). The views of...
Fri May 29, 2020 03:00
Bioengineering, Vol. 7, Pages 49: VLSI Structures for DNA Sequencing—A Survey Bioengineering doi: 10.3390/bioengineering7020049 Authors: Mohammad A. Islam Palash K. Datta Harley Myler DNA sequencing is a critical functionality in biomedical research, and technical advances that improve it have important implications for human health. Novel methods by which sequencing can be accomplished in more accurate, high-throughput, and faster ways are in development. Here, we review VLSI...
Sun May 31, 2020 03:00
Bioengineering, Vol. 7, Pages 48: Computational Biomechanics: In-Silico Tools for the Investigation of Surgical Procedures and Devices Bioengineering doi: 10.3390/bioengineering7020048 Authors: Emanuele Luigi Carniel Ilaria Toniolo Chiara Giulia Fontanella Biomechanical investigations of surgical procedures and devices are usually developed by means of human or animal models. The exploitation of computational methods and tools can reduce, refine, and replace (3R) the animal experimentations...
Sat May 30, 2020 03:00
Biology, Vol. 9, Pages 114: Anti-Inflammatory and Physicochemical Characterization of the Croton Rhamnifolioides Essential Oil Inclusion Complex in β-Cyclodextrin Biology doi: 10.3390/biology9060114 Authors: Oliveira Brito Pereira Bezerra Martins Wanderley Alcântara Rodrigues Cesário Correia de Oliveira Castro Albuquerque da Silva Ribeiro-Filho Coutinho Menezes Quintans-Júnior Araújo Iriti Almeida Menezes Croton rhamnifolioides...
Sat May 30, 2020 03:00
Biology, Vol. 9, Pages 113: Correction: Stalder, et al.; Value of SUVmax for the Prediction of Bone Invasion in Oral Squamous Cell Carcinoma. Biology 2020, 9, 23 Biology doi: 10.3390/biology9060113 Authors: Stalder Schumann Lanzer Hüllner Rupp Broglie Morand The authors would like to make a correction to their published paper [1][...]
Fri May 29, 2020 03:00
Biomedicines, Vol. 8, Pages 144: Higher Epoxyeicosatrienoic Acids in Cardiomyocytes-Specific CYP2J2 Transgenic Mice Are Associated with Improved Myocardial Remodeling Biomedicines doi: 10.3390/biomedicines8060144 Authors: Aliwarga Guo Evangelista Lemaitre Sotoodehnia Gharib Zeldin Liu Totah Elevated cis-epoxyeicosatrienoic acids (EETs) are known to be cardioprotective during ischemia-reperfusion injury in cardiomyocyte-specific overexpressing cytochrome...
Sat May 30, 2020 03:00
Biomedicines, Vol. 8, Pages 145: Tyramine and Amyloid Beta 42: A Toxic Synergy Biomedicines doi: 10.3390/biomedicines8060145 Authors: Sudip Dhakal Ian Macreadie Implicated in various diseases including Parkinson’s disease, Huntington’s disease, migraines, schizophrenia and increased blood pressure, tyramine plays a crucial role as a neurotransmitter in the synaptic cleft by reducing serotonergic and dopaminergic signaling through a trace amine-associated receptor...
Sat May 30, 2020 03:00
Biomedicines, Vol. 8, Pages 142: RNA Sequencing-Based Identification of Ganglioside GD2-Positive Cancer Phenotype Biomedicines doi: 10.3390/biomedicines8060142 Authors: Maxim Sorokin Irina Kholodenko Daniel Kalinovsky Tatyana Shamanskaya Igor Doronin Dmitry Konovalov Aleksei Mironov Denis Kuzmin Daniil Nikitin Sergey Deyev Anton Buzdin Roman Kholodenko The tumor-associated ganglioside GD2 represents an attractive target for cancer immunotherapy. GD2-positive...
Sat May 30, 2020 03:00
Biomedicines, Vol. 8, Pages 143: Caterpillar Venom: A Health Hazard of the 21st Century Biomedicines doi: 10.3390/biomedicines8060143 Authors: Seldeslachts Peigneur Tytgat Caterpillar envenomation is a global health threat in the 21st century. Every direct or indirect contact with the urticating hairs of a caterpillar results in clinical manifestations ranging from local dermatitis symptoms to potentially life-threatening systemic effects. This is mainly due to the action of...
Sat May 30, 2020 03:00
Biomedicines, Vol. 8, Pages 141: Identification of Novel Native Autoantigens in Rheumatoid Arthritis
Biomedicines, Vol. 8, Pages 141: Identification of Novel Native Autoantigens in Rheumatoid Arthritis Biomedicines doi: 10.3390/biomedicines8060141 Authors: Thomas B. G. Poulsen Dres Damgaard Malene Møller Jørgensen Ladislav Senolt Jonathan M. Blackburn Claus H. Nielsen Allan Stensballe The majority of patients diagnosed with rheumatoid arthritis (RA) have developed autoantibodies against neoepitopes in proteins that have undergone post-translational modification, e.g.,...
Fri May 29, 2020 03:00
Biomedicines, Vol. 8, Pages 139: Anti-Anaphylactic Activity of Isoquercitrin (Quercetin-3-O-β-d-Glucose) in the Cardiovascular System of Animals Biomedicines doi: 10.3390/biomedicines8060139 Authors: Jinbong Park Effects of isoquercitrin (IQ) on anaphylactic responses were examined in cardiovascular systems of experimental animals. In pithed rats, IQ at 30 and 100 mg/kg (intravenous) significantly blunted both the initial hypertensive and the ensuing hypotensive responses during anaphylaxis....
Fri May 29, 2020 03:00
Biomedicines, Vol. 8, Pages 140: Synthesis and In Vitro Photodynamic Activity of Cationic Boron Dipyrromethene-Based Photosensitizers against Methicillin-Resistant Staphylococcus aureus Biomedicines doi: 10.3390/biomedicines8060140 Authors: Priyanga Dharmaratne Roy C. H. Wong Jun Wang Pui-Chi Lo Baiyan Wang Ben C. L. Chan Kit-Man Lau Clara B. S. Lau Kwok-Pui Fung Margaret Ip Dennis K. P. Ng A series of cationic boron dipyrromethene (BODIPY) derivatives were...
Fri May 29, 2020 03:00
Biomedicines, Vol. 8, Pages 138: Javamide-II Inhibits IL-6 without Significant Impact on TNF-alpha and IL-1beta in Macrophage-Like Cells Biomedicines doi: 10.3390/biomedicines8060138 Authors: Jae B. Park Renee Peters Quynhchi Pham Thomas T.Y. Wang The main aim of this study is to find a therapeutic compound to inhibit IL-6, not TNF-alpha and IL-1beta, in macrophage-like cells, because the high-levels of IL-6 production by macrophages are reported to cause unfavorable outcomes...
Fri May 29, 2020 03:00
Biomimetics, Vol. 5, Pages 24: Biomimetic Nanomembranes: An Overview Biomimetics doi: 10.3390/biomimetics5020024 Authors: Zoran Jakšić Olga Jakšić Nanomembranes are the principal building block of basically all living organisms, and without them life as we know it would not be possible. Yet in spite of their ubiquity, for a long time their artificial counterparts have mostly been overlooked in mainstream microsystem and nanosystem technologies, being a niche topic at best, instead...
Fri May 29, 2020 03:00
Biomolecules, Vol. 10, Pages 843: The S100B Protein and Partners in Adipocyte Response to Cold Stress and Adaptive Thermogenesis: Facts, Hypotheses, and Perspectives Biomolecules doi: 10.3390/biom10060843 Authors: Jacques Baudier Benoit J Gentil In mammals, adipose tissue is an active secretory tissue that responds to mild hypothermia and as such is a genuine model to study molecular and cellular adaptive responses to cold-stress. A recent study identified a mammal-specific protein...
Sun May 31, 2020 03:00
Biomolecules, Vol. 10, Pages 842: Rats Lacking Dopamine Transporter Display Increased Vulnerability and Aberrant Autonomic Response to Acute Stress Biomolecules doi: 10.3390/biom10060842 Authors: Illiano Bigford Gainetdinov Pardo The activity of the hypothalamus–pituitary–adrenal (HPA) axis is pivotal in homeostasis and presides the adaptative response to stress. Dopamine Transporter (DAT) plays a key role in the regulation of the HPA axis. We used young...
Sun May 31, 2020 03:00
Biomolecules, Vol. 10, Pages 839: Recent Advances in CRISPR/Cas9 Delivery Strategies Biomolecules doi: 10.3390/biom10060839 Authors: Yip The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has revolutionized the field of gene editing. Continuous efforts in developing this technology have enabled efficient in vitro, ex vivo, and in vivo gene editing through a variety of delivery strategies. Viral vectors are commonly used in in vitro, ex vivo, and in vivo...
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 840: Heme-Oxygenase and Kidney Transplantation: A Potential for Target Therapy? Biomolecules doi: 10.3390/biom10060840 Authors: Corona Ekser Gioco Caruso Schipa Veroux Giaquinta Granata Veroux Kidney transplantation is a well-established therapy for patients with end-stage renal disease. While a significant improvement of short-term results has been achieved in the short-term, similar results were not reported in the long-term....
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 841: Pseudouridine Synthase RsuA Captures an Assembly Intermediate that Is Stabilized by Ribosomal Protein S17 Biomolecules doi: 10.3390/biom10060841 Authors: Jayalath Frisbie To Abeysirigunawardena The ribosome is a large ribonucleoprotein complex that synthesizes protein in all living organisms. Ribosome biogenesis is a complex process that requires synchronization of various cellular events, including ribosomal RNA (rRNA) transcription, ribosome...
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 838: Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties Biomolecules doi: 10.3390/biom10060838 Authors: Raluca Bianca Tomoiagă Souad Diana Tork Ilka Horváth Alina Filip Levente Csaba Nagy László Csaba Bencze Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted...
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 837: Rapid Clathrin-Mediated Uptake of Recombinant α-Gal-A to Lysosome Activates Autophagy Biomolecules doi: 10.3390/biom10060837 Authors: Ivanova Dao Kasaci Adewale Fikry Goker-Alpan Enzyme replacement therapy (ERT) with recombinant alpha-galactosidase A (rh-α-Gal A) is the standard treatment for Fabry disease (FD). ERT has shown a significant impact on patients; however, there is still morbidity and mortality in FD, resulting...
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 836: Pan-Proteomic Analysis and Elucidation of Protein Abundance among the Closely Related Brucella Species, Brucella abortus and Brucella melitensis Biomolecules doi: 10.3390/biom10060836 Authors: Murugaiyan Eravci Weise Roesler Sprague Neubauer Wareth Brucellosis is a zoonotic infection caused by bacteria of the genus Brucella. The species, B. abortus and B. melitensis, major causative agents of human brucellosis, share remarkably...
Sat May 30, 2020 03:00
Biomolecules, Vol. 10, Pages 833: The Architectural Dynamics of the Bacterial Flagellar Motor Switch
Biomolecules, Vol. 10, Pages 833: The Architectural Dynamics of the Bacterial Flagellar Motor Switch Biomolecules doi: 10.3390/biom10060833 Authors: Khan The rotary bacterial flagellar motor is remarkable in biochemistry for its highly synchronized operation and amplification during switching of rotation sense. The motor is part of the flagellar basal body, a complex multi-protein assembly. Sensory and energy transduction depends on a core of six proteins that are adapted in different...
Fri May 29, 2020 03:00
Biomolecules, Vol. 10, Pages 835: Green Synthesis of Gold and Silver Nanoparticles Using Leaf Extract of Clerodendrum inerme; Characterization, Antimicrobial, and Antioxidant Activities Biomolecules doi: 10.3390/biom10060835 Authors: Shakeel Ahmad Khan Sammia Shahid Chun-Sing Lee Due to their versatile applications, gold (Au) and silver (Ag) nanoparticles (NPs) have been synthesized by many approaches, including green processes using plant extracts for reducing metal ions. In this...
Fri May 29, 2020 03:00
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