Related ArticlesDevelopmental plasticity shapes social traits and selection in a facultatively eusocial bee. Proc Natl Acad Sci U S A. 2020 May 29;: Authors: Kapheim KM, Jones BM, Pan H, Li C, Harpur BA, Kent CF, Zayed A, Ioannidis P, Waterhouse RM, Kingwell C, Stolle E, Avalos A, Zhang G, McMillan WO, Wcislo WT Abstract Developmental plasticity generates phenotypic variation, but how it contributes to evolutionary change is unclear. Phenotypes of individuals...
Sun May 31, 2020 14:01
Related ArticlesSystemic signaling during abiotic stress combination in plants. Proc Natl Acad Sci U S A. 2020 May 29;: Authors: Zandalinas SI, Fichman Y, Devireddy AR, Sengupta S, Azad RK, Mittler R Abstract Extreme environmental conditions, such as heat, salinity, and decreased water availability, can have a devastating impact on plant growth and productivity, potentially resulting in the collapse of entire ecosystems. Stress-induced systemic signaling...
Sun May 31, 2020 14:01
Related ArticlesMetal-induced sensor mobilization turns on affinity to activate regulator for metal detoxification in live bacteria. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Fu B, Sengupta K, Genova LA, Santiago AG, Jung W, Krzemiński Ł, Chakraborty UK, Zhang W, Chen P Abstract Metal detoxification is essential for bacteria's survival in adverse environments and their pathogenesis in hosts. Understanding the underlying mechanisms is crucial for...
Sat May 30, 2020 13:40
Related ArticlesA family of hyperpolarization-activated channels selective for protons. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Wobig L, Wolfenstetter T, Fechner S, Bönigk W, Körschen HG, Jikeli JF, Trötschel C, Feederle R, Kaupp UB, Seifert R, Berger TK Abstract Proton (H+) channels are special: They select protons against other ions that are up to a millionfold more abundant. Only a few proton channels have been identified so far. Here, we...
Sat May 30, 2020 13:40
Related ArticlesAnisotropy links cell shapes to tissue flow during convergent extension. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Wang X, Merkel M, Sutter LB, Erdemci-Tandogan G, Manning ML, Kasza KE Abstract Within developing embryos, tissues flow and reorganize dramatically on timescales as short as minutes. This includes epithelial tissues, which often narrow and elongate in convergent extension movements due to anisotropies in external forces...
Sat May 30, 2020 13:40
Related ArticlesHow differential privacy will affect our understanding of health disparities in the United States. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Santos-Lozada AR, Howard JT, Verdery AM Abstract The application of a currently proposed differential privacy algorithm to the 2020 United States Census data and additional data products may affect the usefulness of these data, the accuracy of estimates and rates derived from them, and critical...
Sat May 30, 2020 13:40
Related ArticlesTargeted mutation of secretogranin-2 disrupts sexual behavior and reproduction in zebrafish. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Mitchell K, Zhang WS, Lu C, Tao B, Chen L, Hu W, Trudeau VL Abstract The luteinizing hormone surge is essential for fertility as it triggers ovulation in females and sperm release in males. We previously reported that secretoneurin-a, a neuropeptide derived from the processing of secretogranin-2a...
Sat May 30, 2020 13:40
Related ArticlesInhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Meng B, Lan K, Xie J, Lerner RA, Wilson IA, Yang B Abstract The existence of multiple serotypes renders vaccine development challenging for most viruses in the Enterovirus genus. An alternative and potentially more viable strategy for control of these viruses is to develop broad-spectrum...
Sat May 30, 2020 13:40
Related ArticlesStretching and folding sustain microscale chemical gradients in porous media. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Heyman J, Lester DR, Turuban R, Méheust Y, Le Borgne T Abstract Fluid flow in porous media drives the transport, mixing, and reaction of molecules, particles, and microorganisms across a wide spectrum of natural and industrial processes. Current macroscopic models that average pore-scale fluctuations into an effective...
Sat May 30, 2020 13:40
Related ArticlesDynamical processes of interstitial diffusion in a two-dimensional colloidal crystal. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Kim SC, Yu L, Pertsinidis A, Ling XS Abstract In two-dimensional (2D) solids, point defects, i.e., vacancies and interstitials, are bound states of topological defects of edge dislocations and disclinations. They are expected to play an important role in the thermodynamics of the system. Yet very little...
Sat May 30, 2020 13:40
Related ArticlesPI(4,5)P2-dependent regulation of exocytosis by amisyn, the vertebrate-specific competitor of synaptobrevin 2. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Kondratiuk I, Jakhanwal S, Jin J, Sathyanarayanan U, Kroppen B, Pobbati AV, Krisko A, Ashery U, Meinecke M, Jahn R, Fasshauer D, Milosevic I Abstract The functions of nervous and neuroendocrine systems rely on fast and tightly regulated release of neurotransmitters stored in secretory...
Sat May 30, 2020 13:40
Related ArticlesStudies on the mechanism of general anesthesia. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Pavel MA, Petersen EN, Wang H, Lerner RA, Hansen SB Abstract Inhaled anesthetics are a chemically diverse collection of hydrophobic molecules that robustly activate TWIK-related K+ channels (TREK-1) and reversibly induce loss of consciousness. For 100 y, anesthetics were speculated to target cellular membranes, yet no plausible mechanism emerged...
Sat May 30, 2020 13:40
Related ArticlesSimplified model assumptions artificially constrain the parameter range in which selection at the holobiont level can occur. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Daybog I, Kolodny O PMID: 32467160 [PubMed - as supplied by publisher]
Sat May 30, 2020 13:40
Related ArticlesReply to Daybog and Kolodny: Necessary requirements for holobiont-level selection are robust to model assumptions. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: van Vliet S, Doebeli M PMID: 32467159 [PubMed - as supplied by publisher]
Sat May 30, 2020 13:40
Related ArticlesDynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Hernando-Pérez M, Martín-González N, Pérez-Illana M, Suomalainen M, Condezo GN, Ostapchuk P, Gallardo J, Menéndez M, Greber UF, Hearing P, de Pablo PJ, San Martín C Abstract Adenovirus minor coat protein VI contains a membrane-disrupting peptide that is inactive...
Sat May 30, 2020 13:40
Related ArticlesImproved bacterial recombineering by parallelized protein discovery. Proc Natl Acad Sci U S A. 2020 May 28;: Authors: Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM Abstract Exploiting bacteriophage-derived homologous recombination processes has enabled precise, multiplex editing of microbial genomes and the construction of billions of customized genetic...
Sat May 30, 2020 13:40
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/05/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri May 29, 2020 17:24
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/05/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri May 29, 2020 13:20
Publication date: Available online 30 May 2020Source: Allergology InternationalAuthor(s): Federica Filippi, Andrea Sechi, Carlotta Baraldi, Cosimo Misciali, Annalisa Patrizi, Marco Adriano Chessa, Annalucia Virdi, Iria Neri
Sun May 31, 2020 13:59
Related ArticlesA Letter to the Editor on "World Health Organization declares global emergency: A review of the 2019 novel Coronavirus (COVID-19)". Int J Surg. 2020 May 27;: Authors: Pérez-Campos Mayoral L, Mayoral-Andrade G, Pérez-Campos Mayoral E, Hernández-Huerta MT, Pérez-Campos E PMID: 32473239 [PubMed - as supplied by publisher]
Sun May 31, 2020 14:55
Related ArticlesCurrent status of liver transplantation in North America. Int J Surg. 2020 May 27;: Authors: Kirchner VA, Goldaracena N, Sapisochin G, Alejandro RH, Shah SA Abstract Liver transplantation is continuing to grow and evolve in North America. Changes in organ availability, recipient selection, indications and progressive approaches to oncologic treatment have occurred in the last five years. Despite increased activity in deceased and...
Sun May 31, 2020 14:55
Related ArticlesLook at the Patient, Not the Vital Signs: An Invited Commentary on "The Use of Vital Signs in Predicting Surgical Intervention in a South African Population". Int J Surg. 2020 May 27;: Authors: Gallaher J, Charles A PMID: 32473237 [PubMed - as supplied by publisher]
Sun May 31, 2020 14:55
Related ArticlesCommentary on: A Novel solution to the PPE crisis during the Coronavirus pandemic (COVID-19). Int J Surg. 2020 May 26;: Authors: Syed DS, Malik MS, Ominu-Evbota K PMID: 32470595 [PubMed - as supplied by publisher]
Sat May 30, 2020 15:04
Related ArticlesEffects of erector spinae plane block on postoperative pain and side-effects in adult patients underwent surgery: A systematic review and meta-analysis of randomized controlled trials. Int J Surg. 2020 May 24;: Authors: Cai Q, Liu GQ, Huang LS, Yang ZX, Gao ML, Jing R, Liu Z, Pan LH Abstract BACKGROUND: Recently, the effects of erector spinae plane block on postoperative pain have become increasingly controversial. This meta-analysis...
Fri May 29, 2020 13:21
Related ArticlesGreater exercise tolerance in COPD during acute interval, compared to equivalent constant-load, cycle exercise: physiological mechanisms. J Physiol. 2020 May 30;: Authors: Louvaris Z, Chynkiamis N, Spetsioti S, Asimakos A, Zakynthinos S, Wagner PD, Vogiatzis I Abstract KEY POINTS: Exercise intolerance is common in COPD patients. In patients with COPD, we compared an interval exercise (IE) protocol (alternating 30 s at 100% peak work rate...
Sun May 31, 2020 17:52
Related ArticlesHodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. J Physiol. 2020 May 29;: Authors: Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF Abstract Glutamate receptors are essential ligand-gated ion channels in the central nervous system that mediate excitatory synaptic transmission in response to the release of glutamate...
Sat May 30, 2020 14:11
Related ArticlesCerebrovascular reactivity: a new frontier for measuring cognitive health in models of accelerated aging? J Physiol. 2020 May 29;: Authors: Hutton DA, Cavalier AN, Clayton ZS PMID: 32468584 [PubMed - as supplied by publisher]
Sat May 30, 2020 14:11
Related ArticlesKATP channels modulate cerebral blood flow and oxygen delivery during isocapnic hypoxia in humans. J Physiol. 2020 May 28;: Authors: Rocha MP, Campos MO, Mattos JD, Mansur DE, Rocha H, Secher NH, Nóbrega ACL, Fernandes IA Abstract KEY POINTS: ATP-sensitive K+ (KATP) channels mediate hypoxia-induced cerebral vasodilatation and hyperperfusion in animals. We then tested whether KATP channels blockade affects the increase in human cerebral...
Fri May 29, 2020 14:28
Related ArticlesImpact of nicotinamide riboside supplementation on skeletal muscle mitochondria and whole-body glucose homeostasis: challenging the current hypothesis. J Physiol. 2020 May 28;: Authors: Moore MP, Mucinski JM PMID: 32463114 [PubMed - as supplied by publisher]
Fri May 29, 2020 14:28
Related ArticlesMechanisms underlying selective coupling of endothelial Ca2+ signals with eNOS versus IK/SK channels in systemic and pulmonary arteries. J Physiol. 2020 May 28;: Authors: Ottolini M, Daneva Z, Chen YL, Cope EL, Kasetti RB, Zode GS, Sonkusare SK Abstract KEY POINTS: Endothelial cell TRPV4 (TRPV4EC ) channels exert a dilatory effect on the resting diameter of resistance mesenteric and pulmonary arteries. Functional IK/SK channels and eNOS...
Fri May 29, 2020 14:28
Related ArticlesThe antitumor effects of icaritin against breast cancer is related to estrogen receptors. Curr Mol Med. 2020 May 30;: Authors: Tao CC, Wu Y, Gao X, Qiao L, Yang Y, Li F, Zou J, Wang YH, Zhang SY, Li CL, Zhang YY, Sun XD Abstract OBJECTIVE: We aim to investigate the anticancer effects and mechanisms of icaritin against breast cancer. MATERIALS AND METHODS: Both estrogen receptor (ER) positive breast cancer cells MCF-7 and...
Sun May 31, 2020 14:53
Related ArticlesProtective effect of hawthorn extract against genotoxicity induced by benzo(<alpha>)pyrene in C57BL/6 mice. Ecotoxicol Environ Saf. 2020 May 26;200:110761 Authors: Deng J, Chen X, Wang D, Song Y, Chen Y, Ouyang D, Liang Y, Sun Y, Li M Abstract Benzo(<alpha>)pyrene [B(<alpha>)P], widely originated from environmental pollution or food process such as roasting and frying, is a strong mutagen and potent carcinogen. Utilization...
Sat May 30, 2020 15:05
Related ArticlesLncRNA GAS5 participates in the regulation of dexamethasone on androgen receptor -negative and -positive prostate cancer cell proliferation. Mol Cell Probes. 2020 May 26;:101607 Authors: Hu J, Deng J, Cao R, Xiong S, Guo J Abstract BACKGROUND: Androgen receptor (AR) and long non-coding RNAs (lncRNA) play important roles in the initiation and progression of prostate cancer (PCa). The present study was designed to investigate whether...
Sat May 30, 2020 15:05
Related ArticlesDifferential effects of Fe2+ and Fe3+ on osteoblasts and the effects of 1,25(OH)2D3, deferiprone and extracellular calcium on osteoblast viability under iron-overloaded conditions. PLoS One. 2020;15(5):e0234009 Authors: Lertsuwan K, Nammultriputtar K, Nanthawuttiphan S, Tannop N, Teerapornpuntakit J, Thongbunchoo J, Charoenphandhu N Abstract One of the potential contributing factors for iron overload-induced osteoporosis is the iron...
Sat May 30, 2020 15:05
Related ArticlesIrisin, an exercise myokine, potently suppresses tumor proliferation, invasion, and growth in glioma. FASEB J. 2020 May 29;: Authors: Huang CW, Chang YH, Lee HH, Wu JY, Huang JX, Chung YH, Hsu ST, Chow LP, Wei KC, Huang FT Abstract Glioblastoma multiforme is the most common and aggressive glial tumor with poor prognosis. Importantly, effective treatment options for glioblastoma are unmet needs. Obesity and low physical activity have...
Sat May 30, 2020 15:05
Related ArticlesProtein expression profiling identifies differential modulation of homologous recombination by platinum-based antitumor agents. Cancer Chemother Pharmacol. 2020 May 28;: Authors: He G, Xie X, Siddik ZH Abstract PURPOSE: Oxaliplatin and satraplatin demonstrate activity against cisplatin-resistant tumor cells. Although the two platinum analogs are structurally-related, oxaliplatin is more active. Therefore, studies focusing on protein...
Sat May 30, 2020 13:06
Related ArticlesDigitoxin inhibits HeLa cell growth through the induction of G2/M cell cycle arrest and apoptosis in vitro and in vivo. Int J Oncol. 2020 May 25;: Authors: Gan H, Qi M, Chan C, Leung P, Ye G, Lei Y, Liu A, Xue F, Liu D, Ye W, Zhang D, Deng L, Chen J Abstract Cervical cancer is the fourth most common gynecological malignancy affecting the health of women worldwide and the second most common cause of cancer‑related mortality among women...
Sat May 30, 2020 13:06
Related ArticlesmiR‑1299/NOTCH3/TUG1 feedback loop contributes to the malignant proliferation of ovarian cancer. Oncol Rep. 2020 May 25;: Authors: Pei Y, Li K, Lou X, Wu Y, Dong X, Wang W, Li N, Zhang D, Cui W Abstract Recent studies have revealed the oncogenic role of notch reporter 3 (NOTCH3) in ovarian cancer (OC). However, the possible regulators and mechanisms underlying notch receptor 3 (NOTCH3)‑mediated behaviors in OC remain to be completely...
Sat May 30, 2020 13:06
Related ArticlesEllagic acid induces cell cycle arrest and apoptosis via the TGF‑β1/Smad3 signaling pathway in human colon cancer HCT‑116 cells. Oncol Rep. 2020 May 20;: Authors: Zhao J, Li G, Wei J, Dang S, Yu X, Ding L, Shang C, Zhang H, Zhang Z, Chen H, Liu M Abstract Colorectal carcinoma (CRC) is a major type of malignancy worldwide. Ellagic acid (EA), a natural phenolic constituent, has been shown to exhibit anticancer effects. In our previous...
Sat May 30, 2020 13:06
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