Related ArticlesFactors affecting enrollment in randomized controlled trials conducted for patients with metastatic breast cancer. Jpn J Clin Oncol. 2020 May 28;: Authors: Ohsumi S, Mukai H, Takahashi M, Hozumi Y, Akabane H, Park Y, Tokunaga E, Takashima T, Watanabe T, Sagara Y, Kaneko T, Ohashi Y Abstract BACKGROUND: It is critical to obtain informed consent from eligible patients to complete clinical trials. We investigated the factors that affect...
Fri May 29, 2020 13:40
Related ArticlesPatient-specific multi-omics models and the application in personalized combination therapy. Future Oncol. 2020 May 28;: Authors: John A, Qin B, Kalari KR, Wang L, Yu J Abstract The rapid advancement of high-throughput technologies and sharp decrease in cost have opened up the possibility to generate large amount of multi-omics data on an individual basis. The development of high-throughput -omics, including genomics, epigenomics,...
Fri May 29, 2020 13:40
Related ArticlesAnti-HER2 therapy for breast cancer in older patients. Future Oncol. 2020 May 28;: Authors: Goldner M, Franzoi MA, Lago LD, Pondé N Abstract Older patients now form between 30 and 40% of breast cancer (BC) patients. Managing older patients with BC is particularly challenging due to the limited availability of high-quality evidence. In this review we discuss the available evidence on the efficacy and safety of anti-HER2 agents in older...
Fri May 29, 2020 13:40
Related ArticlesClinical Course after a First Episode of Heart Failure: Insights from the Framingham Heart Study. Eur J Heart Fail. 2020 May 28;: Authors: Velagaleti RS, Larson MG, Enserro D, Song RJ, Vasan RS Abstract AIMS: We sought to describe the frequency/type/timing of clinical events, and delineate patterns in their transitions, after a first episode of heart failure (HF). METHODS AND RESULTS: In 1036 Framingham participants with...
Fri May 29, 2020 13:40
Related ArticlesPatient-derived xenografts as compatible models for precision oncology. Lab Anim Res. 2020;36:14 Authors: Cho SY Abstract Cancer is a very heterogeneous disease, displaying heterogeneity between patients (inter-tumoral heterogeneity) and heterogeneity within a patient (intra-tumoral heterogeneity). Precision oncology is a diagnostic and therapeutic approach for cancers based on the stratification of patients using genomic and molecular...
Fri May 29, 2020 13:40
Related ArticlesHow can Australia integrate routine genetic sequencing in oncology: a qualitative study through an implementation science lens. Genet Med. 2020 May 28;: Authors: O'Shea R, Rankin NM, Kentwell M, Gleeson M, Salmon L, Tucker KM, Lewis S, Taylor N Abstract PURPOSE: This study sought to determine genetics and oncology specialists' views of integrating BRCA1 and BRCA2 testing in epithelial ovarian and breast cancer into routine practice....
Fri May 29, 2020 13:40
Related ArticlesAll India Ophthalmological Society - Oculoplastics Association of India consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic. Indian J Ophthalmol. 2020 Jun;68(6):974-980 Authors: Ali MJ, Hegde R, Nair AG, Bajaj MS, Betharia SM, Bhattacharjee K, Chhabra AK, Das JK, Dudeja G, Grover AK, Honavar SG, Kim U, Mahesh L, Mukherjee B, Sethi A, Sharma M, Singh U Abstract Oculoplastic surgeries...
Fri May 29, 2020 13:40
Related ArticlesConsensus Statement on Proton Therapy in Mesothelioma. Pract Radiat Oncol. 2020 May 24;: Authors: Zeng J, Badiyan SN, Garces YI, Wong T, Zhang X, Simone CB, Chang JY, Knopf AC, Mori S, Iwata H, Meijers A, Li H, Bues M, Liu W, Schild SE, Rengan R, International Particle Therapy Co-operative Group (PTCOG) Thoracic Subcommittee Abstract Radiation therapy for mesothelioma remains challenging, as normal tissue toxicity limits the amount...
Fri May 29, 2020 13:40
Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples.
Related ArticlesLiquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples. J Exp Clin Cancer Res. 2020 May 27;39(1):95 Authors: Russano M, Napolitano A, Ribelli G, Iuliani M, Simonetti S, Citarella F, Pantano F, Dell'Aquila E, Anesi C, Silvestris N, Argentiero A, Solimando A, Vincenzi B, Tonini G, Santini D Abstract In a large number of cancer types, treatment selection depends on the presence of specific...
Fri May 29, 2020 13:40
Related ArticlesSingle-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient. Genome Med. 2020 May 27;12(1):47 Authors: Lee HW, Chung W, Lee HO, Jeong DE, Jo A, Lim JE, Hong JH, Nam DH, Jeong BC, Park SH, Joo KM, Park WY Abstract BACKGROUND: Tumor cell-intrinsic mechanisms and complex interactions with the tumor microenvironment contribute...
Fri May 29, 2020 13:40
Related ArticlesPatterns of recurrence in anal cancer: a detailed analysis. Radiat Oncol. 2020 May 27;15(1):125 Authors: Nilsson MP, Nilsson ED, Johnsson A, Leon O, Gunnlaugsson A, Scherman J Abstract BACKGROUND: Anal cancer is a rare disease, which might be the reason for the "one size fits all" approach still used for radiotherapy target contouring. To refine and individualize future guidelines, detailed and contemporary pattern of recurrence studies...
Fri May 29, 2020 13:40
Related Articles2019 Pediatric Initiative Network: Progress, Proceedings, and Plans. J Adolesc Young Adult Oncol. 2020 May 27;: Authors: Nahata L, Gomez-Lobo V, Meacham L, Appiah L, Childress K, Hoefgen H, Dwiggins M, Whiteside S, Bjornard K, Rios J, Anazodo A, Finlayson C, Frias O, Woodruff T, Moravek M Abstract Impairment of fertility and sexual/reproductive health are common after oncologic therapy, and are known to have negative impacts on romantic...
Fri May 29, 2020 13:40
Related ArticlesA Narrative Review on the Use of Photobiomodulation Therapy for the Prevention and Management of Acute Radiodermatitis: Proposed Mechanisms, Current Clinical Outcomes, and Preliminary Guidance for Clinical Studies. Photobiomodul Photomed Laser Surg. 2020 May 27;: Authors: Robijns J, Lodewijckx J, Bensadoun RJ, Mebis J Abstract Objective: A narrative review of the available scientific evidence to identify the current proposals relating...
Fri May 29, 2020 13:40
Related ArticlesEvaluation of Common Variants in the AKNA Gene and Susceptibility to Knee Osteoarthritis Among the Han Chinese. Genet Test Mol Biomarkers. 2020 May 28;: Authors: Zhao T, Ma C, Xie B, Zhao B, Wang W, Liu J Abstract Background: Osteoarthritis (OA) is a complex degenerative joint disease that is associated with both genetic and environmental factors. The AKNA gene, located at 9q32, has recently been identified as being associated with...
Fri May 29, 2020 13:40
Related ArticlesInfluence of the pandemic dissemination of COVID-19 on radiotherapy practice: A flash survey in Germany, Austria and Switzerland. PLoS One. 2020;15(5):e0233330 Authors: Reuter-Oppermann M, Müller-Polyzou R, Wirtz H, Georgiadis A Abstract BACKGROUND: The COVID-19 pandemic has already changed our globalised world and its long-term impact is not yet known. It is apparent that businesses and institutions are increasingly affected. COVID-19...
Fri May 29, 2020 13:40
Related ArticlesBleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity. Crit Care Med. 2019 12;47(12):1766-1772 Authors: Nellis ME, Tucci M, Lacroix J, Spinella PC, Haque KD, Stock A, Steiner ME, Faustino EVS, Zantek ND, Davis PJ, Stanworth SJ, Cholette JM, Parker RI, Demaret P, Kneyber MCJ, Russell RT, Stricker PA, Vogel AM, Willems A, Josephson CD, Luban NLC, Loftis LL, Leteurtre S, Stocker CF, Goobie...
Fri May 29, 2020 13:40
Dunnock social status correlates with sperm speed, but fast sperm does not always equal high fitness
Abstract Sperm competition theory predicts that males should modulate sperm investment according to their social status. Sperm speed, one proxy of sperm quality, also influences the outcome of sperm competition because fast sperm cells may fertilize eggs before slow sperm cells. We evaluated whether the social status of males predicted their sperm speed in a wild population of dunnocks (Prunella modularis ). In addition to the traditional analysis of the average speed of sperm cells per sample,...
Sat May 30, 2020 16:45
Related ArticlesLong-term outcomes of skull base chordoma treated with high-dose carbon-ion radiotherapy. Head Neck. 2020 May 30;: Authors: Koto M, Ikawa H, Kaneko T, Hagiwara Y, Hayashi K, Tsuji H Abstract BACKGROUND: We evaluated the long-term efficacy and safety of carbon-ion radiotherapy (C-ion RT) for skull base chordoma, a rare neoplasm. METHODS: Thirty-four patients with skull base chordoma who were treated with C-ion RT were prospectively...
Sun May 31, 2020 17:08
Related ArticlesVentilated Upper Airway Endoscopic Endonasal Procedure Mask: Surgical Safety in the COVID-19 Era. Oper Neurosurg (Hagerstown). 2020 May 30;: Authors: Helman SN, Soriano RM, Tomov ML, Serpooshan V, Levy JM, Pradilla G, Solares CA Abstract BACKGROUND: COVID-19 poses a risk to the endoscopic skull base surgeon. Significant efforts to improving safety have been employed, including the use of personal protective equipment, preoperative COVID-19...
Sun May 31, 2020 17:08
Related ArticlesPhysical and Vestibular Physical Therapy Referrals in People With Alzheimer Disease. Alzheimer Dis Assoc Disord. 2020 May 27;: Authors: Gandhi P, Klatt BN, Agrawal Y Abstract People with Alzheimer disease (AD) are at increased risk of falls and disproportionately burdened with vestibular impairment compared with healthy older adults. Although physical therapy (PT) and vestibular physical therapy (VPT) are effective rehabilitation interventions...
Sat May 30, 2020 13:07
Related ArticlesFungal ball of the maxillary sinus and the risk of persistent sinus dysfunction after simple antrostomy. Am J Otolaryngol. 2020 May 08;:102541 Authors: Cavada MN, Wong E, Orgain CA, Grayson JW, Alvarado R, Campbell RG, Kalish L, Harvey RJ Abstract BACKGROUND: Maxillary sinus fungal ball is a common cause of unilateral maxillary sinusitis. Fungal balls or mycetomas are primarily treated with surgery to remove the fungus. However, this...
Sat May 30, 2020 13:07
Related ArticlesThe Relationship of High Septal Deviation, the Depth of Olfactory Fossa, and Gera Angle: Is High Septal Deviation Associated With Any Anatomic Abnormalities in the Anterior Skull Base? Ear Nose Throat J. 2020 May 29;:145561320926406 Authors: Onerci Altunay Z, Onerci TM Abstract OBJECTIVE: To investigate the association of high septal deviation with the olfactory fossa depth and Gera angle. METHODS: Fifty-four computed tomography...
Sat May 30, 2020 13:07
Related ArticlesJugular Foramen Metastasis from Lung Cancer: A Case of "A Mass without His Syndrome". J Int Adv Otol. 2019 Dec;15(3):469-471 Authors: Ciavarro G, Bozzetti F, Falcioni M Abstract Jugular foramen (JF) metastasis is rare and often presents as JF syndrome. A 73-year-old male complained of left-sided mastoid pain that irradiated to the neck since the past 3 months. Onset of facial nerve (FN) palsy and persistence of the symptomatology despite...
Sat May 30, 2020 13:07
Related ArticlesPrimary skull base neuroendocrine carcinoma-a case report and review of literature. Radiol Case Rep. 2020 Jul;15(7):1071-1077 Authors: Joshi VV, Thombare P, Verma M, Kamat N, Patkar D Abstract Skull-based neuroendocrine carcinomas are rare tumors with only a few case reports in literature. Here we present an unusual case of primary neuroendocrine carcinoma of the skull in 60-year-old male which was proven on surgical biopsy. The imaging...
Fri May 29, 2020 16:57
Related ArticlesReadability of Printed Online Education Materials on Pituitary Tumors: Untangling a Web of Complexity. Am J Rhinol Allergy. 2020 May 27;:1945892420927288 Authors: Ye MJ, Alwani MM, Harper JL, Buren LMV, Bandali EH, Illing EA, Shipchandler TZ, Ting JY Abstract BACKGROUND: Patients are increasingly turning to the internet for health education. Due to the complex pathophysiology, clinic-diagnostic profile, and management spectrum of pituitary...
Fri May 29, 2020 16:57
Publication date: Available online 30 May 2020Source: Journal of Neuroscience MethodsAuthor(s): N. Buscher, A. Ojeda, M. Francoeur, S. Hulyalkar, C. Claros, T. Tang, A. Terry, A. Gupta, L. Fakhraei, D.S. Ramanathan
Sun May 31, 2020 13:06
Publication date: Available online 30 May 2020Source: Journal of Neuroscience MethodsAuthor(s): Ayako Yoshida, Kouhei Takashima, Tomokazu Shimonaga, Michinori Kadokura, Shotaro Nagase, Shuichi Koda
Sun May 31, 2020 13:06
Publication date: Available online 30 May 2020Source: Journal of Neuroscience MethodsAuthor(s): Jérôme Tubiana, Sébastien Wolf, Thomas Panier, Georges Debregeas
Sun May 31, 2020 13:06
Publication date: Available online 30 May 2020Source: Journal of Neuroscience MethodsAuthor(s): Georgia-Ioanna Kartalou, Thomas Endres, Volkmar Lessmann, Kurt Gottmann
Sun May 31, 2020 13:06
Publication date: Available online 29 May 2020Source: Journal of Neuroscience MethodsAuthor(s): Wei Zhang, Tianyi Zhou, Jing Zhao, Bolun Ji, Zhengping Wu
Sat May 30, 2020 18:06
Publication date: Available online 29 May 2020Source: Journal of Neuroscience MethodsAuthor(s): Josef Wilzén, Anders Eklund, Mattias Villani
Fri May 29, 2020 17:04
Related ArticlesPausing cancer screening during the severe acute respiratory syndrome coronavirus 2pandemic: Should we revisit the recommendations? Eur J Cancer. 2020 May 20;134:86-89 Authors: Amit M, Tam S, Bader T, Sorkin A, Benov A PMID: 32473542 [PubMed - as supplied by publisher]
Sun May 31, 2020 14:40
Related ArticlesAssociation Between Breathing Route, Oxygen Desaturation, and Upper Airway Morphology. Laryngoscope. 2020 May 30;: Authors: Hsu YB, Lan MY, Huang YC, Kao MC, Lan MC Abstract OBJECTIVES/HYPOTHESIS: This study aimed to assess the role of capnography in objectively evaluating breathing routes during drug-induced sleep endoscopy (DISE) and further elucidate the relationship between breathing route, obstructive sleep apnea (OSA) severity,...
Sun May 31, 2020 14:40
Variation in Sleep Stability with Differences in Severity of Sleep-Disordered Breathing in Children.
Related ArticlesVariation in Sleep Stability with Differences in Severity of Sleep-Disordered Breathing in Children. Laryngoscope. 2020 May 30;: Authors: Seo MY, Han MS, Jeong YJ, Lee MK, Park S, Hwang SJ, Lee SH Abstract OBJECTIVES: The aim of this study was to analyze the association between obstructive sleep apnea (OSA) severity and various cardiopulmonary coupling (CPC) parameters in children with OSA. STUDY DESIGN: Retrospective cross-sectional...
Sun May 31, 2020 14:40
Related ArticlesStapes Surgery Outcomes in Patients With Concurrent Otosclerosis and Superior Semicircular Canal Dehiscence. Otol Neurotol. 2020 May 28;: Authors: McClellan J, Nguyen A, Hamilton B, Jethanamest D, Hulla TE, Gupta S Abstract OBJECTIVE: To review outcomes of stapes surgery in patients with concurrent otosclerosis and superior semicircular canal dehiscence. STUDY DESIGN: Retrospective case series. SETTING:: Tertiary...
Sun May 31, 2020 14:40
Related ArticlesOutcomes of Revision Cochlear Implantation. Otol Neurotol. 2020 May 28;: Authors: Kimura KS, O'Connell BP, Nassiri AM, Dedmon MM, Haynes DS, Bennett ML Abstract OBJECTIVES/HYPOTHESIS: This study aims to 1) report revision cochlear implantation (CI) rates at a high-volume CI center, 2) describe classifications for revision CI, 3) analyze audiologic and surgical outcomes in patients who undergo revision CI, and 4) describe a new subcategory...
Sun May 31, 2020 14:40
Related ArticlesTympanoplasty With or Without Balloon Eustachian Tuboplasty for Chronic Suppurative Otitis Media With Obstructive Eustachian Tube Dysfunction. Otol Neurotol. 2020 May 28;: Authors: Hsieh CY, Chang CJ, Sun CH, Lee CY, Gotamco GL, Hsu CJ, Wu HP Abstract OBJECTIVE: To further elucidate the role of balloon Eustachian tuboplasty (BET) in tympanoplasty, we conducted a study to compare the outcomes of tympanoplasty with and without BET for...
Sun May 31, 2020 14:40
Related ArticlesPatient-specific 3D-printed Model-assisted Supracochlear Approach to the Petrous Apex. Otol Neurotol. 2020 May 28;: Authors: Takahashi K, Morita Y, Aizawa N, Ogi M, Nonomura Y, Kitazawa M, Yagi C, Ohshima S, Izumi S, Yamagishi T, Horii A Abstract OBJECTIVE: To present a case of pediatric cholesteatoma that invaded the petrous apex (PA) and discuss the usefulness of preoperative three-dimensional (3D) surgical simulation on a personal...
Sun May 31, 2020 14:40
Related ArticlesDiagnosis of Stapedial Myoclonus Using Endoscopic Visualization. Otol Neurotol. 2020 May 28;: Authors: Barber SR, Barbarite E, Corrales CE Abstract BACKGROUND: Stapedial myoclonus is an uncommon condition involving the rhythmic contraction of the stapedial tendon that may result in a host of symptoms, including tinnitus (1-3). There is a dearth of robust diagnostic modalities to diagnose stapedial myoclonus(4-7), and most patients...
Sun May 31, 2020 14:40
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου