Abstract Orthodox neurocognitive accounts of the bodily sense of agency suggest that the experience of agency arises when action-effects are anticipated accurately. In this paper, I argue that while successful anticipation is crucial for the sense of agency, the role of unsuccessful prediction has been neglected, and that inefficacy and uncertainty are no less central to the sense of agency. I will argue that this is reflected in the phenomenology of agency, which can be characterized...
Abstract Tyler Burge claims in a recent high-profile publication that none of the existing evidence for mental-state attribution by children prior to the age of four or five really supports such a conclusion; and he makes this claim, not just for beliefs, but for mental states of all sorts. In its place, he offers an explanatory framework according to which infants and young children attribute mere information-registering states and teleologically-characterized motivational states,...
The initial online publication contained typesetting errors in section headings and running heads.
The initial online publication contained several typesetting errors.
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Surgical Infections, Ahead of Print.
Surgical Infections, Ahead of Print.
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Abstract Osteoarthritis (OA) is a chronic degenerative joint disease which is greatly affected by the inflammatory response triggered by the NF-κB signaling pathway. Alpinetin (APT) is a natural flavonoid compound, which has been reported to have many important biological activities such as antibacterial, antitumor, and anti-inflammatory. However, the action of its effect on chondrocytes in OA has yet to be elucidated. In this study, we...
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Introduction. Lysosomal storage disorders (LSDs) are rare diseases with more than 50 different entities described today. The spectrum of phenotypes varies from severe to lethal and early-onset disease to mild and late onset. Recognition of the clinical signs and diagnostic workup is challenging and requires expertise. Diagnosis relies on finding abnormal metabolites in urine and serum followed by further enzymatic or molecular analysis. Routine histological examination of the foetal and placental...
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Abstract The solution of the inverse problem of electrocardiology allows the reconstruction of the spatial distribution of the electrical activity of the heart from the body surface electrocardiogram (electrocardiographic imaging, ECGI). ECGI using the equivalent dipole layer (EDL) model has shown to be accurate for cardiac activation times. However, validation of this method to determine repolarization times is lacking. In the present study, we determined the accuracy of the EDL...
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Abstract Primary adrenal insufficiency (PAI) occurs in ~1/5000–1/7000 individuals and is in most cases caused by autoimmune Addison’s disease (AAD). Around 10–20% of women with AAD develop premature ovarian insufficiency (POI) before the age of 40 years. 21-Hydroxylase autoantibodies (21OHAb) are the best single immune marker to classify AAD among PAI patients and autoimmune POI in hypergonadotropic hypogonadic women. In AAD, detection of steroid-cell autoantibodies (StCA) predicts...
Abstract Studies on the TSH receptor (TSHR) have numerous practical applications in vitro and in vivo. For example human monoclonal autoantibodies (MAbs) to the TSHR are useful reagents for in vitro diagnostics. Measurement of TSHR autoantibodies (TRAbs) is helpful in diagnosis and management of autoimmune thyroid disease. Currently available highly sensitive and specific assays to measure TRAbs use the human TSHR MAb M22 instead of the TSH. Furthermore, preparations of the human...
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The reflux symptom index (RSI) has been designed to raise the clinical suspicion of laryngopharyngeal reflux (LPR) in patients presenting with ear, nose, and throat symptoms.
Spasmodic dysphonia is a chronic voice disorder that is characterized by involuntary spasms of the laryngeal muscles during speech production. Botulinum toxin injection into to the laryngeal muscles is the most common and effective treatment of choice for symptoms of spasmodic dysphonia. We present a 44-year-old man with adductor spasmodic dysphonia who was diagnosed as having upper airway obstruction in a polysomnographic examination during sleep after a botulinum toxin injection.
(1) To describe factors influencing the content, timing, and intensity of pre- and postoperative voice therapy for patients undergoing phonosurgery for benign vocal fold lesions. (2) To understand experts’ rationale for decisions made. (3) To critically analyze factors influencing intervention in relation to the wider literature in order to contribute to the development of a complex intervention.
Acoustic analysis is a commonly used method for quantitatively measuring vocal fold function. The accuracy of acoustic analysis depends upon the operator selecting a stable segment of the voice sample to analyze. This paper proposes a novel method to more accurately and reliably select a stable voice segment.
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Abstract Purpose Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health consequences. Sleep fragmentation is a feature of OSA and is often determined by the arousal index (ArI), a metric based on the electroencephalograph (EEG). The ArI has a weak correlation with neurocognitive outcomes in OSA patients. In this study, we examine whether changing from the current minimum EEG arousal duration of 3 s improves...
Abstract Purpose Increased neck circumference is a major risk factor for obstructive sleep apnea (OSA). New data suggest that increased adipose tissue in the neck may be a contributory cause of OSA. The aim of this study was to investigate safety and efficacy of a recently developed injectable ice slurry in selective reduction of neck adipose tissue in a mouse model. Methods...
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Abstract Epithelial ovarian cancer (EOC) is a heterogeneous disease that can be categorized into four major histological subtypes. Its etiology remains poorly understood due mainly to this heterogeneity. Follicle-stimulating hormone (FSH) has been implicated as a risk factor in EOC and has been suggested that may influence the development of specific subtypes. In addition, FSH regulates different aspects of ovarian cancer tumorigenesis. FSH downstream target genes in EOC have...
Abstract Currently world is fighting with global pandemic of coronavirus disease 2019 (COVID-19). At this time of uncertainty, oncologists are struggling to provide appropriate care to cancer patients. They have to weigh risk and benefit of giving cancer treatment vs chances of getting them infected with COVID-19. As cancer patients are immunocompromised and there are high chances of exposure during hospital visits and if they get infected, outcome can be fatal. So through the...
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Publication date: Available online 29 May 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): R. Samarei, S. Mabarian
Publication date: Available online 29 May 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): C.-A. Righini, H. Gil, C. Colombé
Publication date: Available online 29 May 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): C.A. Righini, H. Gil, C. Colombé
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Related ArticlesMetastatic disease in head & neck oncology. Acta Otorhinolaryngol Ital. 2020 Apr;40(SUPPL. 1):S1-S86 Authors: Pisani P, Airoldi M, Allais A, Aluffi Valletti P, Battista M, Benazzo M, Briatore R, Cacciola S, Cocuzza S, Colombo A, Conti B, Costanzo A, Della Vecchia L, Denaro N, Fantozzi C, Galizia D, Garzaro M, Genta I, Iasi GA, Krengli M, Landolfo V, Lanza GV, Magnano M, Mancuso M, Maroldi R, Masini L, Merlano MC, Piemonte M, Pisani S, Prina-Mello...
Related ArticlesFactors influencing CAD/CAM accuracy in fibula free flap mandibular reconstruction. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):138-143 Authors: Sweed AH, Bolzoni AR, Kadubiec A, Beltramini GA, Cherchi A, Baj A PMID: 32469008 [PubMed - in process]
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Related ArticlesEvaluation of neurocognitive abilities in children affected by obstructive sleep apnea syndrome before and after adenotonsillectomy. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):122-132 Authors: Testa D, Carotenuto M, Precenzano F, Russo A, Donadio A, Marcuccio G, Motta G PMID: 32469006 [PubMed - in process]
Related ArticlesPrognostic value of the Sinonasal Outcome Test 22 (SNOT-22) in chronic rhinosinusitis. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):113-121 Authors: Gallo S, Russo F, Mozzanica F, Preti A, Bandi F, Costantino C, Gera R, Ottaviani F, Castelnuovo P PMID: 32469005 [PubMed - in process]
Related ArticlesThe thyro-cricoarytenoid space (TCAS): clinical and prognostic implications in laryngeal cancer. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):106-112 Authors: Lucioni M, Lionello M, Guida F, Sovran F, Canal F, Rizzotto G, Bertolin A PMID: 32469004 [PubMed - in process]
Related ArticlesModified Isshiki's arytenoid adduction without separating cricothyroid and cricoarytenoid joints. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):99-105 Authors: Yumoto E, Sanuki T, Kumai Y, Kodama N PMID: 32469003 [PubMed - in process]
Related ArticlesStem cell markers in oral and oropharyngeal squamous cell carcinomas in relation to the site of origin and HPV infection: clinical implications. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):90-98 Authors: Rizzo D, Graziani C, Gallus R, Zannoni GF, Lucchetti D, Parrilla C, Boninsegna A, Galli J, Paludetti G, Bussu F, Sgambato A PMID: 32469002 [PubMed - in process]
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Publication date: Available online 29 May 2020Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): C. Deveaux, C. Calibre, V. Duquennoy-Martinot, P. Guerreschi, A. Dumont
Publication date: Available online 29 May 2020Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): C. Uzan, F. Marchand, M. Schmidt, J.P. Meningaud, B. Hersant
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Related ArticlesSleep and Sleep Disruption in Amyotrophic Lateral Sclerosis. Curr Neurol Neurosci Rep. 2020 May 27;20(7):25 Authors: Boentert M Abstract PURPOSE OF REVIEW: In amyotrophic lateral sclerosis (ALS), sleep disruption is frequently present and substantially adds to disease burden. This review aims to summarize current knowledge on causes, pathophysiology, and treatment of sleep disturbances in ALS. RECENT FINDINGS: Motor neuron degeneration...
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Objective: To evaluate the treatment efficacy of transcutaneous electrical nerve stimulation (TENS) in patients with tinnitus. Data Sources: PubMed, Scopus, Web of Science, and Cochrane Library were searched for the following concepts: “Transcutaneous Electric Nerve Stimulation” and “Tinnitus.” Study Selection: Inclusion: 1) double- or single-blinded randomized controlled trials; 2) double- or single-blinded randomized comparison trials; 3) prospective or retrospective observational...
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