Κυριακή 31 Μαΐου 2020


WJOG10517G: a multicenter Phase II study of mFOLFOX6 in gastric cancer patients with severe peritoneal metastases.
Related ArticlesWJOG10517G: a multicenter Phase II study of mFOLFOX6 in gastric cancer patients with severe peritoneal metastases. Future Oncol. 2020 May 29;: Authors: Masuishi T, Nakajima TE, Yamazaki K, Hironaka S, Kudo C, Yoshimura K, Muro K Abstract Gastric cancer patients with severe peritoneal metastases, defined as massive ascites and/or inadequate oral intake, have been excluded from clinical trials of new treatments due to poor prognosis and...
Future Oncology.
Sat May 30, 2020 14:08
Patient-specific multi-omics models and the application in personalized combination therapy.
Related ArticlesPatient-specific multi-omics models and the application in personalized combination therapy. Future Oncol. 2020 May 28;: Authors: John A, Qin B, Kalari KR, Wang L, Yu J Abstract The rapid advancement of high-throughput technologies and sharp decrease in cost have opened up the possibility to generate large amount of multi-omics data on an individual basis. The development of high-throughput -omics, including genomics, epigenomics, transcriptomics,...
Future Oncology.
Fri May 29, 2020 14:32
Anti-HER2 therapy for breast cancer in older patients.
Related ArticlesAnti-HER2 therapy for breast cancer in older patients. Future Oncol. 2020 May 28;: Authors: Goldner M, Franzoi MA, Lago LD, Pondé N Abstract Older patients now form between 30 and 40% of breast cancer (BC) patients. Managing older patients with BC is particularly challenging due to the limited availability of high-quality evidence. In this review we discuss the available evidence on the efficacy and safety of anti-HER2 agents in older...
Future Oncology.
Fri May 29, 2020 14:32
The miR‐155/GATA3/IL37 axis modulates the production of proinflammatory cytokines upon TNF‐α stimulation to affect psoriasis development
Abstract Psoriasis is a recrudescent chronic immune‐mediated inflammatory dermatosis; the production and release of proinflammatory cytokines/chemokines such as TNF‐α has been regarded as critical issues during psoriasis pathogenesis. Based on online microarray profiles, the expression of the transcription factor GATA3 was downregulated in psoriasis lesion tissues. In the present study, we searched for miRNAs that might be related to TNF‐α and GATA3 to investigate an in‐depth understanding of psoriasis...
Experimental Dermatology
Sat May 30, 2020 13:07
Prognostic significance of non-urothelial carcinoma of bladder: analysis of nationwide hospital-based cancer registry data in Japan.
Related ArticlesPrognostic significance of non-urothelial carcinoma of bladder: analysis of nationwide hospital-based cancer registry data in Japan. Jpn J Clin Oncol. 2020 May 29;: Authors: Nagumo Y, Kawai K, Kojima T, Shiga M, Kojo K, Tanaka K, Kandori S, Kimura T, Kawahara T, Okuyama A, Higashi T, Nishiyama H Abstract OBJECTIVES: To identify the prognosis of pure non-urothelial carcinoma (non-UC) of bladder and to compare them with those of pure urothelial...
pubmed: "jpn j clin oncol"[j...
Sat May 30, 2020 14:56
Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy.
Related ArticlesConsecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy. Jpn J Clin Oncol. 2020 May 29;: Authors: Sasaki N, Kobayashi K, Saito K, Shimizu S, Suzuki K, Lee J, Yamagishi Y, Shibahara J, Takayama N, Shiokawa Y, Nagane M Abstract OBJECTIVE: The optimal regimen for use of high dose-methotrexate-based chemotherapy in primary central nervous system lymphoma...
pubmed: "jpn j clin oncol"[j...
Sat May 30, 2020 14:56
Age-specific incidence rates of stomach cancer in the world.
Related ArticlesAge-specific incidence rates of stomach cancer in the world. Jpn J Clin Oncol. 2020 May 29;: Authors: Hori M, Okuyama A PMID: 32469062 [PubMed - as supplied by publisher]
pubmed: "jpn j clin oncol"[j...
Sat May 30, 2020 14:56
Temozolomide and etoposide combination for the treatment of relapsed osteosarcoma.
Related ArticlesTemozolomide and etoposide combination for the treatment of relapsed osteosarcoma. Jpn J Clin Oncol. 2020 May 28;: Authors: Akazawa R, Umeda K, Saida S, Kato I, Hiramatsu H, Sakamoto A, Arakawa Y, Sumiyoshi S, Okamoto T, Moritake H, Adachi S, Takita J Abstract The prognosis of patients with relapsed osteosarcoma is extremely poor and the optimal treatment remains to be identified. Here, we retrospectively analysed the clinical outcomes...
pubmed: "jpn j clin oncol"[j...
Fri May 29, 2020 13:05
Initial evaluation of nivolumab in patients with post-operative recurrence of malignant pleural mesothelioma.
Related ArticlesInitial evaluation of nivolumab in patients with post-operative recurrence of malignant pleural mesothelioma. Jpn J Clin Oncol. 2020 May 28;: Authors: Nakamura A, Kondo N, Nakamichi T, Kuroda A, Hashimoto M, Matsumoto S, Yokoi T, Kuribayashi K, Kijima T, Hasegawa S Abstract BACKGROUND: Limited options exist for treating post-recurrence patients with malignant pleural mesothelioma (MPM). This study aimed to evaluate the efficacy and feasibility...
pubmed: "jpn j clin oncol"[j...
Fri May 29, 2020 13:05
Adjuvant treatment of endometrial cancer today.
Related ArticlesAdjuvant treatment of endometrial cancer today. Jpn J Clin Oncol. 2020 May 28;: Authors: Aoki Y, Kanao H, Wang X, Yunokawa M, Omatsu K, Fusegi A, Takeshima N Abstract Endometrial cancer frequently occurs in post-menopausal women, and the endometrium is a well-known site of cancer affecting women. Endometrial cancer is found with genital bleeding and often at an early stage. However, there are some risks of recurrence after hysterectomy....
pubmed: "jpn j clin oncol"[j...
Fri May 29, 2020 13:05
Factors affecting enrollment in randomized controlled trials conducted for patients with metastatic breast cancer.
Related ArticlesFactors affecting enrollment in randomized controlled trials conducted for patients with metastatic breast cancer. Jpn J Clin Oncol. 2020 May 28;: Authors: Ohsumi S, Mukai H, Takahashi M, Hozumi Y, Akabane H, Park Y, Tokunaga E, Takashima T, Watanabe T, Sagara Y, Kaneko T, Ohashi Y Abstract BACKGROUND: It is critical to obtain informed consent from eligible patients to complete clinical trials. We investigated the factors that affect...
pubmed: "jpn j clin oncol"[j...
Fri May 29, 2020 13:05
Normative Exophthalmometry Measurements Vary Among Ethiopian Adults and the Major Ethiopian Ethnic Groups
Purpose: Periocular and orbital anthropometric values vary among races. No studies have established normative exophthalmometry values for Ethiopians or the many Ethiopian ethnic groups. This study established a set of normative anthropometric values for exophthalmometry, and further evaluated whether these measurements differed based on sex or ethnic group. Methods: A cross-sectional study was performed in the ophthalmology department at St. Paul’s Hospital in Addis Ababa, Ethiopia....
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Oscillopsia After Isolated Lateral Wall Decompression Versus Balanced or 3-Wall Decompression
Purpose: To assess the incidence of postoperative masticatory oscillopsia after orbital decompression, comparing results between isolated lateral wall and balanced or 3-wall orbital decompression. Methods: An observational retrospective study was performed, involving 161 consecutive patients who underwent orbital decompression between 2008 and 2018. Patients’ clinical data were registered, and archives were revised for data compilation. Patients were divided into 2 groups according...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Blunderbuss: Ocular and Orbital Injuries Due to Muzzle-Loading Firearms
Purpose: Injury to the eye and/or orbital and adnexal structures associated with antiquated muzzle-loading firearms has not, to our knowledge, been characterized with the exception of a single case report. Methods: A retrospective chart review of 7 patients treated at Vanderbilt University Medical Center from 2003 to 2017 who sustained traumatic injuries to the ocular and/or orbital structures secondary to the discharge of muzzle-loading firearms. The study was approved by the Vanderbilt...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Pain Score Assessment Using Single-Dose IV Ketorolac Only, After External Dacryocystorhinostomy: A Randomized Double/Triple-Blind Placebo-Controlled Trial
Purpose: To assess efficacy of intravenous (IV) ketorolac for postoperative pain control after external dacryocystorhinostomy. Method: Fifty-five patients from January to April 2019 were randomized, to a double-blind prospective interventional study. Intervention arm received IV ketorolac (60 mg/2 ml) immediately post-op, control received IV saline bolus. Pain assessment was done with numerical rating scale pre- and postinjection (day 0) and on day 1. Requirement for analgesics and...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Successful Free Bilamellar Eyelid Grafts for the Repair of Upper and Lower Eyelid Defects in Patients and Laser Speckle Contrast Imaging of Revascularization
Purpose: It is generally believed that large eyelid defects must be repaired using a vascularized flap for 1 lamella, while the other can be a free graft. Recent studies indicate that the pedicle of a tarsoconjunctival flap does not contribute to blood perfusion. The purpose of this study was to explore whether large eyelid defects can be repaired using a free bilamellar eyelid autograft alone. Methods: Ten large upper and lower eyelid defects resulting from tumor excision were reconstructed...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Treatment of Congenital Ptosis in Infants With Associated Amblyopia Using a Frontalis Muscle Flap Eyelid Reanimation Technique
Purpose: To determine the efficacy of a frontalis muscle flap eyelid reanimation technique for correction of severe congenital ptosis and associated amblyopia in infants. Methods: The authors performed a retrospective chart review of patients 12 months of age or younger with unilateral or bilateral congenital ptosis and associated amblyopia or deemed at high risk for amblyopia due to visual deprivation. Following ptosis repair via a frontalis muscle flap technique, primary outcomes...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Bilateral Leukemic Infiltration of the Lacrimal Sac in a Child
An 8-year-old boy with a history of refractory acute lymphoblastic leukemia presented with left-sided periorbital erythema and painless enlargement of the lacrimal sac. MRI revealed a soft tissue mass on the floor of the left orbit, extending into the nasolacrimal sac and duct. Lacrimal sac biopsy was consistent with B-lymphoblastic leukemia. The patient was treated with chemotherapy and radiation with satisfactory remission of local disease. However, similar symptoms emerged shortly after on the...
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Oculoplastic, Orbital, and Lacrimal Care in the Coronavirus Disease 2019 Pandemic: A Shared Experience From Melbourne
No abstract available
Ophthalmic Plastic & Reconstructive Surgery - Published Ahead-of-Print
Tue May 26, 2020 03:00
Erratum to Clinical Analysis and CT 3D-Mediated Precise Internal Fixation in Maxillofacial Fracture.
Related ArticlesErratum to Clinical Analysis and CT 3D-Mediated Precise Internal Fixation in Maxillofacial Fracture. Ear Nose Throat J. 2020 May 29;:145561320930927 Authors: PMID: 32469247 [PubMed - as supplied by publisher]
ear nose throat
Sat May 30, 2020 17:55
Psychophysical Olfactory Tests and Detection of COVID-19 in Patients With Sudden Onset Olfactory Dysfunction: A Prospective Study.
Related ArticlesPsychophysical Olfactory Tests and Detection of COVID-19 in Patients With Sudden Onset Olfactory Dysfunction: A Prospective Study. Ear Nose Throat J. 2020 May 29;:145561320929169 Authors: Lechien JR, Cabaraux P, Chiesa-Estomba CM, Khalife M, Plzak J, Hans S, Martiny D, Calvo-Henriquez C, Barillari MR, Hopkins C, Saussez S Abstract OBJECTIVE: To investigate the coronavirus disease 2019 (COVID-19) status of patients with initial sudden...
ear nose throat
Sat May 30, 2020 17:55
Diffuse Idiopathic Skeletal Hyperostosis of the Cervical Spine: A Risk for Acute Airway Obstruction.
Related ArticlesDiffuse Idiopathic Skeletal Hyperostosis of the Cervical Spine: A Risk for Acute Airway Obstruction. Ear Nose Throat J. 2020 May 29;:145561320931212 Authors: Souza S, Raggio B, Bareiss A, Friedlander P PMID: 32469245 [PubMed - as supplied by publisher]
ear nose throat
Sat May 30, 2020 17:55
A Neck Mass and Stridor in a 54-Day-Old Infant.
Related ArticlesA Neck Mass and Stridor in a 54-Day-Old Infant. Ear Nose Throat J. 2020 May 29;:145561320928205 Authors: Prestwood CA, Mitchell RB, Liu C PMID: 32466733 [PubMed - as supplied by publisher]
ear nose throat
Sat May 30, 2020 13:53
Eagle Syndrome.
Related ArticlesEagle Syndrome. Ear Nose Throat J. 2020 May 29;:145561320930059 Authors: Lee CJ, Chen HC PMID: 32466732 [PubMed - as supplied by publisher]
ear nose throat
Sat May 30, 2020 13:53
Metastatic Renal Cell Carcinoma Presenting as a Rapidly Enlarging Endotracheal Mass Due to Hyperprogression on Anti-PD1 Immunotherapy.
Related ArticlesMetastatic Renal Cell Carcinoma Presenting as a Rapidly Enlarging Endotracheal Mass Due to Hyperprogression on Anti-PD1 Immunotherapy. Ear Nose Throat J. 2020 May 29;:145561320931215 Authors: Hoshal SG, Wickwire PC, Gandour-Edwards RF, Rajappa P, Cates DJ PMID: 32466731 [PubMed - as supplied by publisher]
ear nose throat
Sat May 30, 2020 13:53
The Relationship of High Septal Deviation, the Depth of Olfactory Fossa, and Gera Angle: Is High Septal Deviation Associated With Any Anatomic Abnormalities in the Anterior Skull Base?
Related ArticlesThe Relationship of High Septal Deviation, the Depth of Olfactory Fossa, and Gera Angle: Is High Septal Deviation Associated With Any Anatomic Abnormalities in the Anterior Skull Base? Ear Nose Throat J. 2020 May 29;:145561320926406 Authors: Onerci Altunay Z, Onerci TM Abstract OBJECTIVE: To investigate the association of high septal deviation with the olfactory fossa depth and Gera angle. METHODS: Fifty-four computed tomography...
ear nose throat
Sat May 30, 2020 13:53
Dual innervation of free gracilis muscle for facial reanimation: what we know so far
Publication date: Available online 29 May 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Thanapoom Boonipat, Carrie E. Robertson, Jesse D. Meaike, Krishna S. Vyas, Malke Asaad, Samir Mardini
British Association of Plastic Surgeons
Sat May 30, 2020 13:44
COVID-19 The Great Disruptor
Publication date: Available online 29 May 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Mr. Dariush Nikkhah
British Association of Plastic Surgeons
Fri May 29, 2020 16:55
Patterns of Adult and Paediatric Hand Trauma During the COVID-19 Lockdown
Publication date: Available online 29 May 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Kirti Garude, Ibrahim Natalwala, Benedict Hughes, Christopher West, Waseem Bhat
British Association of Plastic Surgeons
Fri May 29, 2020 16:55
Paramedian forehead flap pedicle division after 7 days using laser-assisted indocyanine green angiography
Publication date: Available online 29 May 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Shannon F. Rudy, Mohammed Abdelwahab, Cherian K. Kandathil, Sam P. Most
British Association of Plastic Surgeons
Fri May 29, 2020 16:55
Emerging Role of Online Virtual Teaching Resources for Medical Student Education in Plastic Surgery: COVID-19 Pandemic and Beyond
Publication date: Available online 29 May 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Jad Abi-Rafeh, Alain J. Azzi
British Association of Plastic Surgeons
Fri May 29, 2020 16:55
Barrier damaging effects of n-propanol in occlusion-modified tandem repeated irritation test: Modulation by exposure factors and atopic skin disease.
Related ArticlesBarrier damaging effects of n-propanol in occlusion-modified tandem repeated irritation test: Modulation by exposure factors and atopic skin disease. Contact Dermatitis. 2020 Jan;82(1):1-9 Authors: Angelova-Fischer I, Soltanipoor M, Stilla T, Fischer TW, Kezic S, Jakasa I Abstract BACKGROUND: Recent studies provide evidence for significant and previously underestimated barrier damaging effects of repeated exposure to 60% n-propanol in...
Alcohol and Homeostasis
Sat May 30, 2020 13:39
Biased S1PR1 Signaling in B Cells Subverts Responses to Homeostatic Chemokines, Severely Disorganizing Lymphoid Organ Architecture.
Related ArticlesBiased S1PR1 Signaling in B Cells Subverts Responses to Homeostatic Chemokines, Severely Disorganizing Lymphoid Organ Architecture. J Immunol. 2019 11 01;203(9):2401-2414 Authors: Hwang IY, Park C, Harrison K, Kehrl JH Abstract Ligand-engaged chemoattractant receptors trigger Gαi subunit nucleotide exchange, stimulating the activation of downstream effector molecules. Activated chemoattractant receptors also dock G protein-coupled receptor...
Alcohol and Homeostasis
Fri May 29, 2020 13:28
Effects of inositol on glucose homeostasis: Systematic review and meta-analysis of randomized controlled trials.
Related ArticlesEffects of inositol on glucose homeostasis: Systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2019 06;38(3):1146-1152 Authors: Miñambres I, Cuixart G, Gonçalves A, Corcoy R Abstract BACKGROUND & AIMS: The effect of inositol on glucose homeostasis is not well characterized. The aim of the present meta-analysis is to synthesize the effects of inositol on glucose homeostasis in different clinical conditions....
Alcohol and Homeostasis
Fri May 29, 2020 13:28
Silencing of CEBPB-AS1 modulates CEBPB expression and resensitizes BRAF-inhibitor resistant melanoma cells to vemurafenib
Introduction of targeted therapy in the treatment of metastatic cutaneous malignant melanoma (CMM) has improved clinical outcome during the last years. However, only in a subset of the CMM patients, this will lead to long-term effects. CEBPB is a transcription factor that has been implicated in various physiological and pathological processes, including cancer development. We have investigated its prognostic impact on CMM and unexpectedly found that higher CEBPB mRNA levels correlated with a longer...
Melanoma Research - Published Ahead-of-Print
Wed May 27, 2020 03:00
Risk factors for otitis media with effusion in children with adenoid hypertrophy.
Related ArticlesRisk factors for otitis media with effusion in children with adenoid hypertrophy. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):133-137 Authors: Songu M, Islek A, Imre A, Aslan H, Aladag I, Pinar E, Oncel S PMID: 32469007 [PubMed - in process]
pubmed: snoring
Sat May 30, 2020 17:25
Evaluation of neurocognitive abilities in children affected by obstructive sleep apnea syndrome before and after adenotonsillectomy.
Related ArticlesEvaluation of neurocognitive abilities in children affected by obstructive sleep apnea syndrome before and after adenotonsillectomy. Acta Otorhinolaryngol Ital. 2020 Apr;40(2):122-132 Authors: Testa D, Carotenuto M, Precenzano F, Russo A, Donadio A, Marcuccio G, Motta G PMID: 32469006 [PubMed - in process]
pubmed: snoring
Sat May 30, 2020 17:25
Ambient air pollutants aggravate association of snoring with prevalent hypertension: results from the Henan Rural Cohort.
Related ArticlesAmbient air pollutants aggravate association of snoring with prevalent hypertension: results from the Henan Rural Cohort. Chemosphere. 2020 May 18;256:127108 Authors: Zhang H, Li S, Chen G, Abdulai T, Liu X, Wang Y, Liang H, Hou J, Huo W, Mao Z, Wang C, Bie R Abstract AIM: We aimed to assess if snoring and ambient air pollutants were jointly associated with prevalent hypertension in a cross-sectional study. METHODS: A total of...
pubmed: snoring
Fri May 29, 2020 17:08
Evaluation of the masticatory biomechanical function in Down syndrome and its Influence on sleep disorders, body adiposity, and salivary parameters.
Related ArticlesEvaluation of the masticatory biomechanical function in Down syndrome and its Influence on sleep disorders, body adiposity, and salivary parameters. J Oral Rehabil. 2020 May 28;: Authors: Gomes MF, Giannasi LC, Fillietaz-Bacigalupo E, de Mancilha GP, de Carvalho Silva GR, Soviero LD, da Silva GYS, de Miguel Nazario L, Dos Santos Dutra MT, Silvestre PR, de Oliveria LVF, Nacif SR, Oliveira EF, Serafim IM, Pereira BD, Greca AR, das Graças Vilela Goulart M,...
pubmed: snoring
Fri May 29, 2020 17:08

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