Recurrent pleomorphic adenoma of the parotid gland: A comparison of radiographic and pathologic tumor burden. Am J Otolaryngol. 2020 Jul 08;41(6):102642 Authors: Rooker SA, Nagelschneider AA, Moore EJ, Yin LX, Price DL, Janus JR, Kasperbauer JL, Van Abel KM Abstract PURPOSE: To compare recurrent pleomorphic adenoma tumor burden as detected on magnetic resonance and computerized tomography imaging with postoperative histopathology. ...
Medical data science in rhinology: Background and implications for clinicians. Am J Otolaryngol. 2020 Jul 02;41(6):102627 Authors: Jun YJ, Jung J, Lee HM Abstract BACKGROUND: An important challenge of big data is using complex information networks to provide useful clinical information. Recently, machine learning, and particularly deep learning, has enabled rapid advances in clinical practice. The application of artificial intelligence...
Revisiting a rare disease: Oral cavity basaloid squamous cell carcinoma at a high-volume tertiary center. Am J Otolaryngol. 2020 Jul 07;41(6):102645 Authors: Hicks MD, Lin D, Buczek EP Abstract OBJECTIVES: Rare diseases are often poorly understood, and this study sought to investigate the incidence of a rare disease entity, basaloid squamous cell carcinoma (BSCC) of the oral cavity (OC) at a tertiary care medical center and to assess its...
Pulmonary deposition of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler formulated using co-suspension delivery technology in healthy male subjects. Eur J Pharm Sci. 2020 Jul 15;:105472 Authors: Israel S, Kumar A, DeAngelis K, Aurivillius M, Dorinsky P, Roche N, Usmani OS Abstract This gamma scintigraphy imaging study assessed pulmonary, extrathoracic and regional lung deposition patterns of a radiolabelled...
Related Articles Images in cytology: Fine needle aspiration cytology of BRAFV600E positive anaplastic thyroid carcinoma. Diagn Cytopathol. 2020 Jul 18;: Authors: Xing MH, van den Akker T, Gonzalez-Velazquez C, Urken ML, Chen H PMID: 32681762 [PubMed - as supplied by publisher]
Related Articles Reflux as a Risk Factor for Morbidity after Pediatric Tonsillectomy: A National Cohort of Inpatients. Laryngoscope. 2020 Jul 18;: Authors: Chorney SR, Zur KB, Buzi A Abstract OBJECTIVE: Gastroesophageal reflux (GER) has been identified as a risk factor for complications following pediatric tonsillectomy. The primary objective of this study was to examine outcomes after tonsillectomy among children with GER using a nationwide...
Related Articles Factors Associated With Distribution of Female Otolaryngology Residents in United States. Laryngoscope. 2020 Jul 18;: Authors: Sulibhavi A, Kaufmann MR, Shetty KR, Wulu JA, Tracy LF, Levi JR Abstract OBJECTIVE: The gender balance within medicine, and specifically within otolaryngology, is equalizing. It is important to determine the factors that impact the distribution of female residents among otolaryngology programs in...
Related Articles Prognostic value of preoperative systemic inflammation response index in patients with oral squamous cell carcinoma: Propensity score-based analysis. Head Neck. 2020 Jul 18;: Authors: Lin J, Chen L, Chen Q, Zhuang Z, Bao X, Qian J, Hong Y, Yan L, Lin L, Shi B, Qiu Y, Pan L, Wei L, Zheng X, Wang J, Liu F, He B, Chen F Abstract BACKGROUND: The aim of the study was to elucidate the relationship between systemic inflammation...
Related Articles Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer. Head Neck. 2020 Jul 18;: Authors: Lindegaard AM, von Buchwald C, Rasmussen JH, Specht L, Vogelius IR, Zamani M, Woller NC, Lelkaitis G, Friborg J Abstract BACKGROUND: Isolated regional recurrences following head-neck squamous-cell carcinomas (HNSCC) are often accessible for curatively intended salvage treatment. Factors...
Related Articles Sinonasal undifferentiated carcinoma: Institutional trend toward induction chemotherapy followed by definitive chemoradiation. Head Neck. 2020 Jul 18;: Authors: London NR, Mohyeldin A, Daoud G, Gamez ME, Blakaj D, Bonomi M, Prevedello DM, Carrau RL Abstract BACKGROUND: Recent reports have investigated the nascent role of induction chemotherapy for sinonasal undifferentiated carcinoma (SNUC). The goal of this study was to...
Related Articles An audit of cytopathology in the oral and maxillofacial region: 18-year experience. Cytopathology. 2020 Jul 18;: Authors: Pérez-de-Oliveira ME, Wagner VP, do Amaral-Silva GK, Leite AA, Lopes MA, Roger Santos-Silva A, Jorge Júnior J, de Almeida OP, Vargas PA Abstract OBJECTIVE: The aim of this study was to perform an audit of oral and maxillofacial specimens submitted for cytologic diagnosis to verify the importance of this...
Related Articles Granulomatous inflammation in lymph nodes of the head and neck-a retrospective analysis of causes in a population with very low incidence of tuberculosis. Immunol Res. 2020 Jul 17;: Authors: Flyger TF, Larsen SR, Kjeldsen AD Abstract The purpose of this study was to investigate the risk of the patient having: (1) TB, (2) sarcoidosis, (3) atypical mycobacteria, or (4) malignant disease, if FNAC or histology from a cervical...
Related Articles Is a Prophylactic Central Compartment Neck Dissection Required in Papillary Thyroid Carcinoma Patients with Clinically Involved Lateral Compartment Lymph Nodes? Ann Surg Oncol. 2020 Jul 17;: Authors: Harries V, McGill M, Wang LY, Tuttle RM, Wong RJ, Shaha AR, Shah JP, Patel SG, Ganly I Abstract BACKGROUND: The 2015 American Thyroid Association guidelines state that a prophylactic central compartment neck dissection (PCND)...
Related Articles Immune Checkpoint Inhibitors for Patients Aged ≥ 75 Years with Advanced Cancer in First- and Second-Line Settings: A Meta-Analysis. Drugs Aging. 2020 Jul 17;: Authors: Landre T, Des Guetz G, Chouahnia K, Fossey-Diaz V, Culine S Abstract BACKGROUND: The impact of aging on the effectiveness of immune checkpoint inhibitors (ICIs) remains controversial, and little is known on the subject in adults aged ≥ 75 years. ...
Related Articles Gene therapy development in hearing research in China. Gene Ther. 2020 Jul 17;: Authors: Zhang Z, Wang J, Li C, Xue W, Xing Y, Liu F Abstract Sensorineural hearing loss, the most common form of hearing impairment, is mainly attributable to genetic mutations or acquired factors, such as aging, noise exposure, and ototoxic drugs. In the field of gene therapy, advances in genetic and physiological studies and profound increases...
Related Articles Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming. Nat Commun. 2020 Jul 17;11(1):3595 Authors: Cheung KCP, Fanti S, Mauro C, Wang G, Nair AS, Fu H, Angeletti S, Spoto S, Fogolari M, Romano F, Aksentijevic D, Liu W, Li B, Cheng L, Jiang L, Vuononvirta J, Poobalasingam TR, Smith DM, Ciccozzi M, Solito E, Marelli-Berg FM Abstract Endothelial barrier (EB) breaching is a frequent...
Related Articles Induction and Regulation of the Immunoproteasome Subunit β5i (PSMB8) in Laryngeal and Hypopharyngeal Carcinoma Cells. Med Sci Monit. 2020 Jul 07;26:e923621 Authors: Chen NX, Liu K, Liu X, Zhang XX, Han DY Abstract BACKGROUND The ubiquitin-proteasome pathway (UPP) is closely associated with the occurrence and progression of cancer, and the 5i immunoproteasome subunit is an important antitumor target in UPP. This study aimed...
Related Articles Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Sci Immunol. 2020 Jul 17;5(49): Authors: Andrews LP, Somasundaram A, Moskovitz JM, Szymczak-Workman AL, Liu C, Cillo AR, Lin H, Normolle DP, Moynihan KD, Taniuchi I, Irvine DJ, Kirkwood JM, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA Abstract Mechanisms of resistance to cancer immunotherapy remain poorly understood. Lymphocyte...
Related Articles Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma. Br J Ophthalmol. 2020 Jul 17;: Authors: Ford JR, Rubin ML, Frank SJ, Ning J, Debnam JM, Bell D, El-Naggar A, Ferrarotto R, Esmaeli B Abstract BACKGROUND/AIMS: To identify prognostic factors for local recurrence, distant metastasis and disease-specific survival (DSS) for lacrimal gland carcinoma. ...
Related Articles Respiratory Muscle Strength Training to Improve Vocal Function in Patients with Presbyphonia. J Voice. 2020 Jul 14;: Authors: Desjardins M, Halstead L, Simpson A, Flume P, Bonilha HS Abstract BACKGROUND AND OBJECTIVE: The effects of presbyphonia are compounded by the decline in respiratory function that occurs with age. Commonly recommended exercises to optimize the use of respiratory muscles during speech, such as diaphragmatic...
Related Articles Terminology, Definitions, and Classification in the Imaging of Laryngoceles. Curr Probl Diagn Radiol. 2020 Jun 26;: Authors: Slonimsky G, Hawng G, Goldenberg D, Gagnon E, Slonimsky E Abstract OBJECTIVE: We aim to better define the anatomy, criteria, and classification of laryngoceles, and to raise the awareness to potential mimickers and anatomical variants leading to misdiagnosis. METHODS: A retrospective review...
Related Articles Does microscopic experience influence learning curve in endoscopic ear surgery? A multicentric study. Auris Nasus Larynx. 2020 Jul 15;: Authors: Lucidi D, Fernandez IJ, Botti C, Amorosa L, Alicandri-Ciufelli M, Villari D, Presutti L Abstract OBJECTIVE: The aim of the present study was to illustrate the learning curve of endoscopic type-1 tympanoplasty comparing experts in microscopic otology versus neophyte surgeons. ...
Related Articles Anastomosing Hemangioma of the Larynx: A Unicorn among Head and Neck Tumors. Ann Otol Rhinol Laryngol. 2020 Jul 17;:3489420943640 Authors: Dutta R, Kakkar A, Sakthivel P, Kumar R Abstract OBJECTIVE: Anastomosing hemangioma (AH) is a novel tumor of vascular origin. Though well-documented in the kidney and retroperitoneum, only a single case has been documented in the head and neck, and AH in larynx has not been described....
Related Articles Patient-reported quality-of-life outcomes in relation to provider-assessed adverse events during head and neck radiotherapy. J Patient Rep Outcomes. 2020 Jul 16;4(1):60 Authors: Niska JR, Thorpe CS, Halyard MY, Tan AD, Atherton PJ, Dueck AC, Patel SH, Sloan JA Abstract PURPOSE: To assess the relationship between patient-reported quality-of-life (QOL) outcomes and provider-assessed adverse events (AEs) during head-and-neck...
Related Articles Porf-2 Inhibits Tumor Cell Migration Through the MMP-2/9 Signaling Pathway in Neuroblastoma and Glioma. Front Oncol. 2020;10:975 Authors: Li XY, Huang GH, Liu QK, Yang XT, Wang K, Luo WZ, Liang TS, Yuan SP, Zhen YW, Yan DM Abstract Tumor migration and invasion are key pathological processes that contribute to cell metastasis as well as treatment failure in patients with malignant tumors. However, the mechanisms governing...
Related Articles Molecular gene mutation profiles, TMB and the impact of prognosis in Caucasians and east Asian patients with lung adenocarcinoma. Transl Lung Cancer Res. 2020 Jun;9(3):629-638 Authors: Gu W, Wang N, Gu W, Qiu Y, Zhang H, Liang J, Zhou T, Ma L, Cai W, Feng W, Chen L Abstract Background: The difference in molecular gene mutation profile, tumor mutational burden (TMB) and their prognostic effects in lung adenocarcinoma between...
Related Articles p16 Immunohistochemical Expression in Head and Neck Squamous Cell Carcinoma: Association With Prognostic Parameters. Cureus. 2020 Jun 13;12(6):e8601 Authors: Hashmi AA, Younus N, Naz S, Irfan M, Hussain Z, Shaikh ST, Ali J, Faridi N, Najam J, Shoaib M, Hashmi SK Abstract Background p16 is a tumor suppressor gene, over expression of which is considered as a surrogate marker of oncogenic human papillomavirus (HPV) infection....
Related Articles Substernal goiter excision in a Jehovah's Witness. Proc (Bayl Univ Med Cent). 2020 Jul;33(3):462-464 Authors: Kholaki O, Wentland TR, Kim RY Abstract Jehovah's Witnesses present a unique challenge in oral and head and neck surgery. We report a case of a substernal goiter excised on a Jehovah's Witness without the use of blood transfusion, in accordance with the patient's beliefs. Additionally, we review the literature on...
Related Articles Effects of radiation and MediPort placement on the development of thoracic outlet syndrome. Proc (Bayl Univ Med Cent). 2020 Jul;33(3):446-447 Authors: Grimsley C, Corn R, Hohmann S, Eidt J, Smith B, Pearl G, Grimsley BR Abstract We present a patient who exemplifies the interplay of factors contributing to the development of venous-type thoracic outlet syndrome. The patient was treated with both radiation and chemotherapy...
Related Articles Cutaneous signet-ring cell squamous cell carcinoma. Proc (Bayl Univ Med Cent). 2020 Jul;33(3):424-426 Authors: Findeis SK, Readinger A, Mitchell J, Agarwal A Abstract Cutaneous signet-ring cell squamous cell carcinoma (SRCSCC) is a rare variant, most commonly occurring in the head and neck. We report a case of a 66-year-old transgender woman with an ulcerated growing facial mass measuring 5.6 × 4.0 × 2.0 cm. Histological...
Related Articles Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes. Cancers (Basel). 2020 Jul 14;12(7): Authors: Tang Z, Chen H, Hong L, Tang G, Toruner GA, Wang W, Roy Chowdhuri S, Yin W, Jung HS, Gu J, Routbort MJ, Zhang J, Khoury JD, Medeiros LJ Abstract ALK FISH analyses of multiple specimens occasionally yield inconsistent intersample results in lung cancer patients, posing clinical...
Related Articles Periodontal Diseases as Putative Risk Factors for Head and Neck Cancer: Systematic Review and Meta-Analysis. Cancers (Basel). 2020 Jul 14;12(7): Authors: Gopinath D, Kunnath Menon R, K Veettil S, George Botelho M, Johnson NW Abstract Whether "periodontal disease" can be considered as an independent risk factor for head and neck cancer (HNC) remains controversial. The aim of the current meta-analysis was to quantitatively...
Outcomes of microdebrider-assisted versus radiofrequency-assisted inferior turbinate reduction surgery: a systematic review and meta-analysis of interventional randomised studies. Rhinology. 2020 Jul 17;: Authors: Mirza AA, Alandejani TA, Shawli HY, Alsamel MS, Albakrei MO, Abdulazeem HM Abstract BACKGROUND: The microdebrider technique was introduced in clinical practice to provide a better outcome in nasal obstruction caused by inferior...
Juvenile xanthogranuloma of the subdural spaces mimicking chronic hematoma with positive FDG uptake on PET: case report. J Neurosurg Pediatr. 2020 Jul 17;:1-5 Authors: Kahn JA, Waltz JT, Eskandari RM, Welsh CT, Antonucci MU Abstract The authors report an unusual presentation of juvenile xanthogranuloma (JXG), a non-Langerhans cell histiocytosis of infancy and early childhood. This entity typically presents as a cutaneous head or neck nodule...
Sexual satisfaction in nasopharyngeal carcinoma survivors: Rates and determinants. Oral Oncol. 2020 Jul 14;109:104865 Authors: McDowell L, So N, Keshavarzi S, Xu W, Rock K, Chan B, Waldron J, Bernstein LJ, Hui Huang S, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Ringash J Abstract OBJECTIVES: Sexual health problems have been identified as an unmet need in head and neck cancer (HNC) survivors. In particular,...
Advantages of double density alignment of fNIRS optodes to evaluate cortical activities related to phonological short-term memory using NIRS-SPM. Hear Res. 2020 Jul 08;395:108024 Authors: Yamazaki H, Kanazawa Y, Omori K Abstract Phonological short-term memory (STM) and working memory (WM) capacity, which is temporal storage of phonological information, facilitates language development. This capacity is often impaired in cochlear implant...
Proton pump inhibitor administration in neonates and infants. Lack of consensus - An ASPO survey. Int J Pediatr Otorhinolaryngol. 2020 Jul 03;137:110200 Authors: Zoizner-Agar G, Rotsides JM, Shao Q, Rickert S, Ward R, Greifer M, April M Abstract OBJECTIVE: Laryngopharyngeal and Gastroesophageal reflux (LPR and GER) are distinct clinical entities that present with a range of non-specific symptoms. The exact prevalence in the pediatric population...
A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311. Oral Oncol. 2020 Jul 14;110:104797 Authors: Ferris RL, Flamand Y, Holsinger FC, Weinstein GS, Quon H, Mehra R, Garcia JJ, Hinni ML, Gross ND, Sturgis EM, Duvvuri U, Méndez E, Ridge JA, Magnuson JS, Higgins KA, Patel MR, Smith RB, Karakla DW, Kupferman ME, Malone JP, Judson BL, Richmon J, Boyle JO, Bayon...
Prognostic significance of quantitative metastatic lymph node burden on magnetic resonance imaging in nasopharyngeal carcinoma:a retrospective study of 1224 patients from two centers. Radiother Oncol. 2020 Jul 14;: Authors: Ma H, Liang S, Cui C, Zhang Y, Xie F, Zhou J, Dong A, Chen M, Xie C, Li H, Liu L Abstract BACKGROUND AND PURPOSE: The number of metastatic lymph nodes (LNs) has been demonstrated to be an important prognosticator in...
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