Related Articles Alpha-Lipoic Acid Mediates Clearance of Iron Accumulation by Regulating Iron Metabolism in a Parkinson's Disease Model Induced by 6-OHDA. Front Neurosci. 2020;14:612 Authors: Tai S, Zheng Q, Zhai S, Cai T, Xu L, Yang L, Jiao L, Zhang C Abstract The disruption of neuronal iron homeostasis and oxidative stress are related to the pathogenesis of Parkinson's disease (PD). Alpha-lipoic acid (ALA) is a naturally occurring enzyme...
Fri Jul 17, 2020 23:11
Related Articles Asymmetric Differences in the Gray Matter Volume and Functional Connections of the Amygdala Are Associated With Clinical Manifestations of Alzheimer's Disease. Front Neurosci. 2020;14:602 Authors: Wu X, Wu Y, Geng Z, Zhou S, Wei L, Ji GJ, Tian Y, Wang K Abstract Objective: Asymmetry is a subtle but pervasive aspect of the human brain, which may be altered in several neuropsychiatric conditions. Magnetic resonance imaging (MRI)...
Fri Jul 17, 2020 23:11
Related Articles Integrity of Multiple Memory Systems in Individuals With Untreated Obstructive Sleep Apnea. Front Neurosci. 2020;14:580 Authors: Jackson ML, Rayner G, Wilson S, Schembri R, Sommers L, O'Donoghue FJ, Jackson GD, Tailby C Abstract Obstructive sleep apnea (OSA) is associated with working- and autobiographical-memory impairments, and high rates of mood disorder. This study aimed to examine (i) behavioral responses and (ii) neural...
Fri Jul 17, 2020 23:11
The After-Effect of Accelerated Intermittent Theta Burst Stimulation at Different Session Intervals.
Related Articles The After-Effect of Accelerated Intermittent Theta Burst Stimulation at Different Session Intervals. Front Neurosci. 2020;14:576 Authors: Yu F, Tang X, Hu R, Liang S, Wang W, Tian S, Wu Y, Yuan TF, Zhu Y Abstract Objective: The study aims to investigate the after-effect of three sessions of intermittent theta-burst stimulation (iTBS) on motor cortical excitability. The iTBS was induced over the primary motor cortex (M1) at...
Fri Jul 17, 2020 23:11
Related Articles Functional Connectivity Abnormalities of Brain Regions With Structural Deficits in Primary Insomnia Patients. Front Neurosci. 2020;14:566 Authors: Xie D, Qin H, Dong F, Wang X, Liu C, Xue T, Hao Y, Liu B, Yuan K, Yu D Abstract Objectives: The present study examined the abnormal resting state functional connections (RSFCs) in structural deficit brain regions of primary insomnia (PI) patients. Methods: Thirty-three PI...
Fri Jul 17, 2020 23:11
Related Articles Corrigendum: Cerebral Autoregulation Evidenced by Synchronized Low Frequency Oscillations in Blood Pressure and Resting-State fMRI. Front Neurosci. 2020;14:544 Authors: Whittaker JR, Driver ID, Venzi M, Bright MG, Murphy K Abstract [This corrects the article DOI: 10.3389/fnins.2019.00433.]. PMID: 32670004 [PubMed - in process]
Fri Jul 17, 2020 23:11
Related Articles Brainstem Organoids From Human Pluripotent Stem Cells. Front Neurosci. 2020;14:538 Authors: Eura N, Matsui TK, Luginbühl J, Matsubayashi M, Nanaura H, Shiota T, Kinugawa K, Iguchi N, Kiriyama T, Zheng C, Kouno T, Lan YJ, Kongpracha P, Wiriyasermkul P, Sakaguchi YM, Nagata R, Komeda T, Morikawa N, Kitayoshi F, Jong M, Kobashigawa S, Nakanishi M, Hasegawa M, Saito Y, Shiromizu T, Nishimura Y, Kasai T, Takeda M, Kobayashi H, Inagaki Y, Tanaka Y,...
Fri Jul 17, 2020 23:11
Related Articles Exploring the Connection Between Binary and Spiking Neural Networks. Front Neurosci. 2020;14:535 Authors: Lu S, Sengupta A Abstract On-chip edge intelligence has necessitated the exploration of algorithmic techniques to reduce the compute requirements of current machine learning frameworks. This work aims to bridge the recent algorithmic progress in training Binary Neural Networks and Spiking Neural Networks-both of which are...
Fri Jul 17, 2020 23:11
Related Articles Effects of Drugs of Abuse on the Blood-Brain Barrier: A Brief Overview. Front Neurosci. 2020;14:513 Authors: Pimentel E, Sivalingam K, Doke M, Samikkannu T Abstract The use of psychostimulants and alcohol disrupts blood-brain barrier (BBB) integrity, resulting in alterations to cellular function, and contributes to neurotoxicity. The BBB is the critical boundary of the central nervous system (CNS) where it maintains intracellular...
Fri Jul 17, 2020 23:11
Smoking cessation prolongs survival in female cancer survivors - the Danish nurse cohort. Eur J Oncol Nurs. 2020 Jul 04;47:101796 Authors: Heberg J, Simonsen MK, Thomsen T, Zoffmann V, Danielsen AK Abstract PURPOSE: To explore smoking cessation between cancer survivors and cancer-free women, and the potential survival benefits from smoking cessation in cancer surviving women. METHOD: We pooled 46,334 responses from the Danish...
Sun Jul 19, 2020 13:04
Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma amongst chronic lymphocytic leukemia patients. J Am Acad Dermatol. 2020 Jul 15;: Authors: Kleinstern G, Rishi A, Achenbach SJ, Rabe KG, Kay NE, Shanafelt TD, Ding W, Leis JF, Norman AD, Call TG, Cerhan JR, Parikh SA, Baum CL, Slager SL Abstract BACKGROUND: The incidence of cutaneous squamous cell carcinoma (SCC) in chronic lymphocytic leukemia...
Sun Jul 19, 2020 13:04
Unique geospatial accumulations of uveal melanoma. Am J Ophthalmol. 2020 Jul 15;: Authors: Orloff M, Brennan M, Sato S, Shields CL, Shields JA, Lally S, Mashayekhi A, Mason J, Materin M, Mastrangelo M, Sato T Abstract BACKGROUND: Uveal melanoma (UM) is the most common primary malignant eye tumor in adults, though rare with 2500 cases diagnosed annually in the US. Despite a growing understanding of the molecular characteristics, there remains...
Sun Jul 19, 2020 13:04
Related Articles Modern therapeutic approaches for the treatment of malignant liver tumours. Nat Rev Gastroenterol Hepatol. 2020 Jul 17;: Authors: Petrowsky H, Fritsch R, Guckenberger M, De Oliveira ML, Dutkowski P, Clavien PA Abstract Malignant liver tumours include a wide range of primary and secondary tumours. Although surgery remains the mainstay of curative treatment, modern therapies integrate a variety of neoadjuvant and adjuvant...
Sun Jul 19, 2020 13:04
Related Articles A microdosing study with 99mTc-PHC-102 for the SPECT/CT imaging of primary and metastatic lesions in renal cell carcinoma patients. J Nucl Med. 2020 Jul 17;: Authors: Kulterer OC, Pfaff S, Wadsak W, Garstka N, Remzi M, Vraka C, Nics L, Bootz F, Cazzamalli S, Krall N, Neri D, Haug AR Abstract 99mTc-PHC-102 is a 99mTc-labeled derivative of acetazolamide, a high-affinity small organic ligand of Carbonic Anhydrase IX (CAIX)....
Sun Jul 19, 2020 13:04
Related Articles Urinary incontinence and erectile dysfunction in patients with localized or locally advanced prostate cancer: A nationwide observational study. Urol Oncol. 2020 Jul 15;: Authors: Vernooij RWM, Cremers RGHM, Jansen H, Somford DM, Kiemeney LA, van Andel G, Wijsman BP, Busstra MB, van Moorselaar RJA, Wijnen EM, Pos FJ, Hulshof MCCM, Hamberg P, van den Berkmortel F, Hulsbergen-van de Kaa CA, van Leenders GJLH, Fütterer JJ, van Oort IM, Aben KKH...
Sun Jul 19, 2020 13:04
Related Articles Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects. Mol Cancer. 2020 Jul 17;19(1):116 Authors: Li C, Jiang P, Wei S, Xu X, Wang J Abstract Regulatory T cells (Tregs) characterized by the expression of the master transcription factor forkhead box protein p3 (Foxp3) suppress anticancer immunity, thereby hindering protective immunosurveillance of tumours and...
Sun Jul 19, 2020 13:04
Related Articles Usefulness of 18F-FDG PET/CT in Patients with Cardiac Implantable Electronic Device Suspected of Late Infection. J Clin Med. 2020 Jul 15;9(7): Authors: Rubini G, Ferrari C, Carretta D, Santacroce L, Ruta R, Iuele F, Lavelli V, Merenda N, D'Agostino C, Sardaro A, Niccoli Asabella A Abstract The presence of a cardiovascular implantable electronic device (CIED) can be burdened by complications such as late infections that...
Sun Jul 19, 2020 13:04
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Jul 18, 2020 15:49
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Jul 18, 2020 13:46
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 17, 2020 22:37
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jul 17, 2020 13:29
Related Articles Evaluation of breast surgical oncology complications after single agent versus dual agent HER2 targeted neoadjuvant chemotherapy. Am J Surg. 2020 Jun 30;: Authors: Cullom ME, Amin AL, Balanoff CR, Wagner JL, Larson KE Abstract BACKGROUND: The aim of this study was to determine whether differing neoadjuvant chemotherapy (NAC) regimens for HER2 positive breast cancer (HER2+ BC) are associated with differing surgical complications....
Sun Jul 19, 2020 16:47
Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial. J Clin Oncol. 2020 Jul 17;:JCO2000147 Authors: Saura C, Oliveira M, Feng YH, Dai MS, Chen SW, Hurvitz SA, Kim SB, Moy B, Delaloge S, Gradishar W, Masuda N, Palacova M, Trudeau ME, Mattson J, Yap YS, Hou MF, De Laurentiis M, Yeh YM, Chang HT, Yau T, Wildiers H, Haley B, Fagnani D, Lu...
Sat Jul 18, 2020 16:24
Related Articles DE-ESCALATING TREATMENT FOR HER2-POSITIVE EARLY BREAST CANCER. Trans Am Clin Climatol Assoc. 2020;131:119-126 Authors: Osborne CK, Schiff R, Rimawi M Abstract HER2-positive breast cancers are defined by amplification of the cerbB2 gene and overexpression of its protein HER2. This subtype of breast cancer is aggressive, grows rapidly, and metastasizes early. However, new treatments targeting HER2 combined with chemotherapy have...
Sat Jul 18, 2020 16:24
Related Articles ERBB2 mRNA Expression and Response to Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer. Cancers (Basel). 2020 Jul 14;12(7): Authors: Griguolo G, Brasó-Maristany F, González-Farré B, Pascual T, Chic N, Saurí T, Kates R, Gluz O, Martínez D, Paré L, Tsvetkova V, Pesantez D, Vidal M, Adamo B, Muñoz M, Galván P, Barberá L, Cuatrecasas M, Christgen M, Kreipe H, Monge-Escartín I, Villagrasa P, Soy D, Giarratano T, Dieci MV, Conte P,...
Sat Jul 18, 2020 16:24
Related Articles Defining radiologic complete response using a correlation of presurgical ultrasound and mammographic localization findings with pathological complete response following neoadjuvant chemotherapy in breast cancer. Eur J Radiol. 2020 Jul 03;130:109146 Authors: Makanjuola DI, Alkushi A, Al Anazi K Abstract PURPOSE: Breast cancer affects a significant number of patients younger than 40 years in the Gulf and breast conservative treatment...
Sat Jul 18, 2020 00:09
Related Articles Hsp90 inhibition and co-incubation with pertuzumab induce internalization and degradation of trastuzumab: Implications for use of T-DM1. J Cell Mol Med. 2020 Jul 16;: Authors: Skeie M, Nikolaysen F, Chitano Y, Stang E Abstract The receptor tyrosine kinase HER2 is associated with a number of human malignancies and is an important therapeutic target. The antibody-drug conjugate trastuzumab emtansine (T-DM1; Kadcyla® ) is recommended...
Sat Jul 18, 2020 00:09
Related Articles Polyphenol-Enriched Extracts from Trapa acornis Husks Inhibit Her2-Positive SK-BR-3 Breast Cancer Cell Proliferation and In Vivo Tumor Angiogenesis. Nutr Cancer. 2020 Jul 16;:1-12 Authors: Huang X, Li J, Li M, Huang J, Jiang X, Fu H, Wu J, Bao M, Wang S, Zhang M, Gao G Abstract The study aimed to investigate the antitumor effects of Trapa acornis husks (TAH) extract on SK-BR-3 cells of Her2-positive breast cancer. The bioactive...
Sat Jul 18, 2020 00:09
Related Articles ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers. Mol Cancer Ther. 2020 Jul 15;: Authors: Skidmore L, Sakamuri S, Knudsen NA, Hewet AG, Milutinovic S, Barkho W, Biroc SL, Kirtley J, Marsden R, Storey K, Lopez I, Yu W, Fang SY, Yao S, Gu Y, Tian F Abstract First generation antibody drug conjugates (ADCs) are heterogeneous...
Sat Jul 18, 2020 00:09
[Factors Contributing to the Occurrence of Edema in Breast Cancer Patients Receiving DTX Treatment].
Related Articles [Factors Contributing to the Occurrence of Edema in Breast Cancer Patients Receiving DTX Treatment]. Gan To Kagaku Ryoho. 2020 Jul;47(7):1069-1073 Authors: Uno K, Takada S, Hashishita H, Endo M Abstract Edema is a frequent side effect observed in patients receiving docetaxel hydrate(DTX)treatment. However, the factors contributing to the development of edema in breast cancer patients receiving this treatment have not been completely...
Sat Jul 18, 2020 00:09
Related Articles Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes. Neuroradiology. 2020 Jul 16;: Authors: So TY, Ai QH, Lam WKJ, Qamar S, Poon DMC, Hui EP, Mo FKF, Chan KCA, King AD Abstract PURPOSE: Anatomical imaging criteria for the diagnosis of malignant head and neck nodes may not always be reliable. This study aimed to evaluate the diagnostic value of conventional...
Sat Jul 18, 2020 16:28
Spontaneous and apnea arousals from sleep in preterm infants. Pediatr Res. 2020 Jul 18;: Authors: Seppä-Moilanen M, Andersson S, Kirjavainen T Abstract BACKGROUND: The significance of arousal in apnea termination in preterm infants is not known. METHODS: We investigated the appearance of arousals from sleep with polysomnography for 21 preterm infants at a median age of 36 gestational weeks. RESULTS: The polysomnographic appearance...
Sun Jul 19, 2020 13:14
Related Articles 1-Year Follow-up of Single Anastomosis Sleeve Ileal (SASI) Bypass in Morbid Obese Patients: Efficacy and Concerns. Obes Surg. 2020 Jul 17;: Authors: Kermansaravi M, Kabir A, Pazouki A Abstract BACKGROUND: Single anastomosis sleeve ileal (SASI) bypass is a new bariatric and metabolic procedure that has both restrictive and malabsorptive effects. This study was conducted to assess both the efficacy and safety of this procedure...
Sun Jul 19, 2020 13:14
Related Articles Clinical indication of nasal surgery for the CPAP intolerance in obstructive sleep apnea with nasal obstruction. Auris Nasus Larynx. 2020 Jul 14;: Authors: Iwata N, Nakata S, Inada H, Kimura A, Hirata M, Yasuma F Abstract OBJECTIVE: The role of isolated nasal surgery for obstructive sleep apnea (OSA) patients with nasal obstruction, especially for an intolerance for continuous positive airway pressure (CPAP), is unclear. The...
Sun Jul 19, 2020 13:14
Low prognostic value of novel nocturnal oxygen saturation metrics in patients with obstructive sleep apnea and high cardiovascular event risk: post-hoc analyses of the SAVE study. Chest. 2020 Jul 14;: Authors: Linz D, Loffler KA, Sanders P, Catcheside P, Anderson CS, Zheng D, Quan W, Barnes M, Redline S, McEvoy RD, Baumert M, SAVE (Sleep Apnea Cardiovascular Endpoints) Investigators Abstract BACKGROUND: Traditional methods for quantifying obstructive...
Sat Jul 18, 2020 13:39
Self-reported snoring patterns predict stroke events in high-risk patients with obstructive sleep apnea: post-hoc analyses of the SAVE study. Chest. 2020 Jul 14;: Authors: Li J, McEvoy RD, Zheng D, Loffler KA, Wang X, Redline S, Woodman RJ, Anderson CS Abstract BACKGROUND: The relation of snoring to risks of stroke and other major cardiovascular (CV) events is uncertain. RESEARCH QUESTION: We aimed to determine associations of snoring...
Sat Jul 18, 2020 13:39
Cardiorespiratory Monitoring Data during Sleep in One-year-old Healthy Canadian Infants. Ann Am Thorac Soc. 2020 Jul 17;: Authors: Vézina K, Mariasine J, Young R, Reyna M, Lu Z, Subbarao P, Moraes TJ, Becker AB, Turvey SE, Sears MR, Lefebvre DL, Azad MB, Rasmussen C, Pei J, Narang I, Mandhane PJ Abstract RATIONALE: Sleep study interpretation in children needs to be based on age-specific normal values. While several studies have reported normal...
Sat Jul 18, 2020 13:39
Related Articles Intraoperative identification of mixed activation profiles during hypoglossal nerve stimulation. J Clin Sleep Med. 2020 Jul 17;: Authors: Sturm JJ, Lee CH, Modik O, Suurna MV Abstract STUDY OBJECTIVES: The effectiveness of hypoglossal nerve stimulation (HGNS) in the treatment of obstructive sleep apnea (OSA) depends upon the selective stimulation of nerve fibers that innervate tongue muscles that produce tongue protrusion (genioglossus)...
Sat Jul 18, 2020 13:39
Related Articles Best reoperative strategy for failed fundoplication: redo fundoplication or conversion to Roux-en-Y gastric diversion? Surg Endosc. 2020 Jul 16;: Authors: Shao JM, Elhage SA, Prasad T, Gersin K, Augenstein VA, Colavita PD, Heniford BT Abstract BACKGROUND: Failed fundoplication is a difficult reoperative challenge, with limited evidence differentiating outcomes of a redo fundoplication versus conversion to Roux-en-Y anatomy with...
Sat Jul 18, 2020 13:39
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