Antibiotics, Vol. 9, Pages 423: Policies to Reduce Antibiotic Consumption: The Impact in the Basque Country Antibiotics doi: 10.3390/antibiotics9070423 Authors: Paula Rojas Fernando Antoñanzas In 2013, a change in copayment rate was introduced in the Basque Country (one year later than in the other regions in Spain), and improvements were made to drug packaging. In 2014, a National Program Against Bacterial Resistance (Spanish abbreviation: PRAN) was approved. The aim of this study...
Antibiotics, Vol. 9, Pages 422: Antibacterial and Anti-Inflammatory Effects of Novel Peptide Toxin from the Spider Pardosa astrigera Antibiotics doi: 10.3390/antibiotics9070422 Authors: Min Kyoung Shin In-Wook Hwang Yunkyung Kim Seung Tae Kim Wonhee Jang Seungki Lee Woo Young Bang Chang-Hwan Bae Jung-Suk Sung The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new...
Antibiotics, Vol. 9, Pages 421: Analysing the Initial Bacterial Adhesion to Evaluate the Performance of Antifouling Surfaces Antibiotics doi: 10.3390/antibiotics9070421 Authors: Patrícia Alves Joana Maria Moreira João Mário Miranda Filipe José Mergulhão The aim of this work was to study the initial events of Escherichia coli adhesion to polydimethylsiloxane, which is critical for the development of antifouling surfaces. A parallel plate flow cell was used to perform the initial...
Antibiotics, Vol. 9, Pages 420: Unveiling the Properties of Thai Stingless Bee Propolis via Diminishing Cell Wall-Associated Cryptococcal Melanin and Enhancing the Fungicidal Activity of Macrophages Antibiotics doi: 10.3390/antibiotics9070420 Authors: Ketsaya Mamoon Patcharin Thammasit Anupon Iadnut Kuntida Kitidee Usanee Anukool Yingmanee Tragoolpua Khajornsak Tragoolpua Cryptococcus neoformans, a life-threatening human yeast pathogen, has the ability to produce melanin,...
Antibiotics, Vol. 9, Pages 419: Optimising Interventions for Catheter-Associated Urinary Tract Infections (CAUTI) in Primary, Secondary and Care Home Settings Antibiotics doi: 10.3390/antibiotics9070419 Authors: Wanat Borek Atkins Sallis Ashiru-Oredope Beech Butler Chadborn Hopkins Jones McNulty Roberts Shaw Taborn Tonkin-Crine Catheter-associated urinary tract infections (CAUTI) are common yet preventable. Healthcare professional...
Antibiotics, Vol. 9, Pages 418: Narrow-Spectrum Antibacterial Agents—Benefits and Challenges Antibiotics doi: 10.3390/antibiotics9070418 Authors: Richard A. Alm Sushmita D. Lahiri The number of antibacterial agents in clinical and preclinical development possessing activity against a narrow spectrum of bacterial pathogens is increasing, with many of them being nontraditional products. The key value proposition hinges on sparing antibiotic use and curtailing the emergence of resistance,...
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Antioxidants, Vol. 9, Pages 637: Emerging Strategies to Protect the Skin from Ultraviolet Rays Using Plant-Derived Materials Antioxidants doi: 10.3390/antiox9070637 Authors: Yong Chool Boo Sunlight contains a significant amount of ultraviolet (UV) ray, which leads to various effects on homeostasis in the body. Defense strategies to protect from UV rays have been extensively studied, as sunburn, photoaging, and photocarcinogenesis are caused by excessive UV exposure. The primary lines...
Antioxidants, Vol. 9, Pages 636: Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm Antioxidants doi: 10.3390/antiox9070636 Authors: Eddie W. Fakhouri Stephen J. Peterson Janish Kothari Ragin Alex Joseph I. Shapiro Nader G. Abraham Coronaviruses are very large RNA viruses that originate in animal reservoirs and include severe acute respiratory distress syndrome (SARS) and Middle East respiratory syndrome (MERS) and other inconsequential...
Antioxidants, Vol. 9, Pages 635: The Antioxidant Role of Soy and Soy Foods in Human Health Antioxidants doi: 10.3390/antiox9070635 Authors: Gianluca Rizzo Oxidative stress seems to play a role in many chronic diseases, such as cardiovascular diseases, diabetes, and some cancers. Research is always looking for effective approaches in the prevention and treatment of these pathologies with safe strategies. Given the central role of nutrition, the identification of beneficial healthy foods...
Antioxidants, Vol. 9, Pages 634: Effect of Sechium edule var. nigrum spinosum (Chayote) on Telomerase Levels and Antioxidant Capacity in Older Adults with Metabolic Syndrome Antioxidants doi: 10.3390/antiox9070634 Authors: Graciela Gavia-García Juana Rosado-Pérez Itzen Aguiñiga-Sánchez Edelmiro Santiago-Osorio Víctor Manuel Mendoza-Núñez Patients with metabolic syndrome (MetS) have a redox imbalance, due to a decay in antioxidant capacity. Oxidative stress (OxS) is considered...
Antioxidants, Vol. 9, Pages 633: Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells Antioxidants doi: 10.3390/antiox9070633 Authors: Jasek-Gajda Jurkowska Jasińska Lis The mitogen-activated protein kinase (MAPK)/extracellular signal kinase (ERK) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signal transduction pathways have been implicated in the pathogenesis of leukemia. The aim of this...
Antioxidants, Vol. 9, Pages 631: Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease Antioxidants doi: 10.3390/antiox9070631 Authors: Hanafy Burrows Prenzler Hill With an increase in the longevity and thus the proportion of the elderly, especially in developed nations, there is a rise in pathological conditions that accompany ageing, such as neurodegenerative disorders. Alzheimer’s disease (AD) is a neurodegenerative...
Antioxidants, Vol. 9, Pages 630: Antioxidant and Anti-Inflammatory Effect of Nrf2 Inducer Dimethyl Fumarate in Neurodegenerative Diseases Antioxidants doi: 10.3390/antiox9070630 Authors: Sarah A. Scuderi Alessio Ardizzone Irene Paterniti Emanuela Esposito Michela Campolo Neurodegenerative diseases (NDs) represents debilitating conditions characterized by degeneration of neuronal cells in specific brain areas, causing disability and death in patients. In the pathophysiology...
Antioxidants, Vol. 9, Pages 632: Effects of Processing on Polyphenolic and Volatile Composition and Fruit Quality of Clery Strawberries Antioxidants doi: 10.3390/antiox9070632 Authors: Garzoli Cairone Carradori Mocan Menghini Paolicelli Ak Zengin Cesa Strawberries belonging to cultivar Clery (Fragaria x ananassa (Duchesne ex Weston)), cultivated in central Italy were subjected to a multi-methodological experimental study. Fresh and defrosted strawberries...
Antioxidants, Vol. 9, Pages 628: New Advances in the Determination of Free and Bound Phenolic Compounds of Banana Passion Fruit Pulp (Passiflora tripartita, var. Mollissima (Kunth) L.H. Bailey) and Their In Vitro Antioxidant and Hypoglycemic Capacities Antioxidants doi: 10.3390/antiox9070628 Authors: Elisa Giambanelli Ana Maria Gómez-Caravaca Arancha Ruiz-Torralba Eduardo Jesús Guerra-Hernández Jorge Geovanny Figueroa-Hurtado Belén García-Villanova Vito Verardo Banana...
Antioxidants, Vol. 9, Pages 629: Novel Antioxidant Packaging Films Based on Poly(ε-Caprolactone) and Almond Skin Extract: Development and Effect on the Oxidative Stability of Fried Almonds Antioxidants doi: 10.3390/antiox9070629 Authors: Arantzazu Valdés García Nerea Juárez Serrano Ana Beltrán Sanahuja María Carmen Garrigós Antioxidant films based on poly(ε-caprolactone) (PCL) containing almond skin extract (ASE) were developed for food packaging applications. The...
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Arts, Vol. 9, Pages 81: Road to Fame: Social Trajectory of Takahata Isao Arts doi: 10.3390/arts9030081 Authors: Yoshioka This paper examines how Takahata Isao’s reputation as a filmmaker was established, focusing on the period between Horus: The Prince of the Sun (1968) and Only Yesterday (1991), using Pierre Bourdieu’s concepts of “field” and “consecration”. Through detailed analysis of promotion strategies, popular and critical...
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Atmosphere, Vol. 11, Pages 763: Wildfire Pyroconvection and CAPE: Buoyancy’s Drying and Atmospheric Intensification—Fort McMurray Atmosphere doi: 10.3390/atmos11070763 Authors: Atoossa Bakhshaii Edward A. Johnson Kiana Nayebi The accurate prediction of wildfire behavior and spread is possible only when fire and atmosphere simulations are coupled. In this work, we present a mechanism that causes a small fire to intensify by altering the atmosphere. These alterations are caused by...
Atmosphere, Vol. 11, Pages 762: Impacts of Vegetation and Topography on Land Surface Temperature Variability over the Semi-Arid Mountain Cities of Saudi Arabia Atmosphere doi: 10.3390/atmos11070762 Authors: Bindajam Mallick AlQadhi Singh Hang Land surface temperature (LST) can fully reflect the water–heat exchange cycle of the earth surface that is important for the study of environmental change. There is little research on LST in the semi-arid region of Abha-Khamis-Mushyet,...
Atmosphere, Vol. 11, Pages 761: High-Resolution Solar Climate Atlas for Greece under Climate Change Using the Weather Research and Forecasting (WRF) Model Atmosphere doi: 10.3390/atmos11070761 Authors: Theodoros Katopodis Iason Markantonis Nadia Politi Diamando Vlachogiannis Athanasios Sfetsos In the context of climate change and growing energy demand, solar technologies are considered promising solutions to mitigate Greenhouse Gas (GHG) emissions and support sustainable...
Atmosphere, Vol. 11, Pages 758: Investigating the Interannual Variability of the Boreal Summer Water Vapor Source and Sink over the Tropical Eastern Indian Ocean-Western Pacific Atmosphere doi: 10.3390/atmos11070758 Authors: Zou Qiao Chao Chen Hu Li Feng Using the four-times daily and monthly-mean reanalysis datasets of NCEP/NCAR for the 1958 to 2018 period, we investigate the interannual variability of the June-July-August (JJA)–mean water vapor source...
Atmosphere, Vol. 11, Pages 756: Dependence of Mass—Dimensional Relationships on Median Mass Diameter
Atmosphere, Vol. 11, Pages 756: Dependence of Mass—Dimensional Relationships on Median Mass Diameter Atmosphere doi: 10.3390/atmos11070756 Authors: Ding McFarquhar Nesbitt Chase Poellot Wang Retrievals of ice cloud properties require accurate estimates of ice particle mass. Empirical mass–dimensional (m–D) relationships in the form m=aDb are widely used and usually universally applied across the complete range of particle sizes. For the first...
Atmosphere, Vol. 11, Pages 757: Evaluation of WRF-Chem Predictions for Dust Deposition in Southwestern Iran Atmosphere doi: 10.3390/atmos11070757 Authors: A. Foroushani Opp Groll Nikfal The relationships between monthly recorded ground deposition rates (GDRs) and the ‎spatiotemporal characteristics of dust concentrations in southwest Iran were investigated. A simulation by the Weather Research and Forecasting Model coupled with the ‎Chemistry modeling system...
Atmosphere, Vol. 11, Pages 760: Characterization, Pollution Sources, and Health Risk of Ionic and Elemental Constituents in PM2.5 of Wuhan, Central China Atmosphere doi: 10.3390/atmos11070760 Authors: Weiqian Wang Weilin Zhang Shiyang Dong Shinichi Yonemachi Senlin Lu Qingyue Wang Atmospheric PM2.5 samples from Wuhan, China were collected during a winter period of February and a summer period of August in 2018. The average PM2.5 mass concentration in winter reached 112...
Atmosphere, Vol. 11, Pages 759: Assessment of Air Pollution with Polychlorinated Dibenzodioxins (PCDDs) and Polychlorinated Dibenzofuranes (PCDFs) in Lithuania Atmosphere doi: 10.3390/atmos11070759 Authors: Vigilija Klima Renata Chadyšienė Rūta Ivanec-Goranina Dainius Jasaitis Vaida Vasiliauskienė Polychlorinated dibenzodioxins and polychlorinated dibenzofurans (PCDD/F) are highly bioavailable in humans, either through direct inhalation or indirectly by trophic transfer from...
Atmosphere, Vol. 11, Pages 755: Ozone Trends from Two Decades of Ground Level Observation in Malaysia Atmosphere doi: 10.3390/atmos11070755 Authors: Fatimah Ahamad Paul T. Griffiths Mohd Talib Latif Liew Juneng Chung Jing Xiang We examine the change in surface ozone and its precursor behavior over 20 years at four locations in western Peninsular Malaysia which have undergone urban-commercial development. Trend and correlation analyses were carried out on ozone and oxides...
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Biology, Vol. 9, Pages 174: Sperm Quality Assessment in Honey Bee Drones Biology doi: 10.3390/biology9070174 Authors: Jesús L. Yániz Miguel A. Silvestre Pilar Santolaria The quality of honey bee drone semen is relevant in different contexts, ranging from colony productivity to pathology, toxicology and biodiversity preservation. Despite its importance, considerably less knowledge is available on this subject for the honey bee when compared to other domestic animal species. A proper...
Biology, Vol. 9, Pages 173: Effect of Edge-to-Edge Mitral Valve Repair on Chordal Strain: Fluid-Structure Interaction Simulations Biology doi: 10.3390/biology9070173 Authors: Milan Toma Daniel R. Einstein Keshav Kohli Sheridan L. Caroll Charles H. Bloodworth Richard P. Cochran Karyn S. Kunzelman Ajit P. Yoganathan Edge-to-edge repair for mitral valve regurgitation is being increasingly performed in high-surgical risk patients using minimally invasive mitral clipping...
Biology, Vol. 9, Pages 172: Impact of the Static Magnetic Field on Growth, Pigments, Osmolytes, Nitric Oxide, Hydrogen Sulfide Phenylalanine Ammonia-Lyase Activity, Antioxidant Defense System, and Yield in Lettuce Biology doi: 10.3390/biology9070172 Authors: Arafat Abdel Hamed Abdel Latef Mona F. A. Dawood Halimeh Hassanpour Maryam Rezayian Nabil A. Younes Magnetic fields are an unavoidable physical factor affecting living organisms. Lettuce seeds (Lactuca sativa var. cabitat...
Biology, Vol. 9, Pages 171: Development of a Low-Cost and High-Efficiency Culture Medium for Bacteriocin Lac-B23 Production by Lactobacillus plantarum J23 Biology doi: 10.3390/biology9070171 Authors: Jianming Zhang Yushan Bu Chengcheng Zhang Huaxi Yi Daqun Liu Jingkai Jiao At present, De Man, Rogosa and Sharpe (MRS) broth is the medium of choice for promoting bacteriocin production. However, this medium is expensive and not applicable for large-scale production. Therefore,...
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Biomedicines, Vol. 8, Pages 227: Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article Biomedicines doi: 10.3390/biomedicines8070227 Authors: Cohan Lucassen Smoot Brink Chen Sphingosine-1-phosphate (S1P), via its G-protein-coupled receptors, is a signaling molecule with important regulatory properties on numerous, widely varied cell types. Five S1P receptors (S1PR1-5) have been identified, each with effects...
Biomedicines, Vol. 8, Pages 226: Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis Biomedicines doi: 10.3390/biomedicines8070226 Authors: Jehan Aram Nanci Frakich Elena Morandi Mohammed Alrouji Amal Samaraweera David Onion Ian Spendlove Sergio L. Colombo Radu Tanasescu Bruno Gran Cris S. Constantinescu Granulocyte macrophage colony stimulating factor (GM-CSF)...
Biomedicines, Vol. 8, Pages 225: Pharmacological Effects of a Novel Bradykinin-Related Peptide (RR-18) from the Skin Secretion of the Hejiang Frog (Ordorrana hejiangensis) on Smooth Muscle Biomedicines doi: 10.3390/biomedicines8070225 Authors: Xiaowei Zhou Jie Xu Ruimin Zhong Chengbang Ma Mei Zhou Zhijian Cao Xinping Xi Chris Shaw Tianbao Chen Lei Wang Hang Fai Kwok Bradykinin (BK) and bradykinin-related peptides (BRPs), which were identified from a diversity...
Biomedicines, Vol. 8, Pages 223: Key Milestones Contributing to the Understanding of the Mechanisms Underlying Fibromyalgia Biomedicines doi: 10.3390/biomedicines8070223 Authors: Geoffrey Littlejohn Emma Guymer The promulgation of the American College of Rheumatology (ACR) 1990 criteria for fibromyalgia (FM) classification has significantly contributed to an era of increased research into mechanisms that underlie the disorder. The previous emphasis on putative peripheral nociceptive...
Biomedicines, Vol. 8, Pages 221: Drug-Induced Gingival Overgrowth: The Effect of Cyclosporin A and Mycophenolate Mophetil on Human Gingival Fibroblasts Biomedicines doi: 10.3390/biomedicines8070221 Authors: Dorina Lauritano Giulia Moreo Luisa Limongelli Annalisa Palmieri Francesco Carinci Drug-induced gingival overgrowth may occur after a chronic administration of three classes of systemic drugs: Anticonvulsants, immunosuppressants, and calcium channel blockers. This study...
Biomedicines, Vol. 8, Pages 222: Amino Acid Metabolites Associated with Chronic Kidney Disease: An Eight-Year Follow-Up Korean Epidemiology Study Biomedicines doi: 10.3390/biomedicines8070222 Authors: Hansongyi Lee Han Byul Jang Min-Gyu Yoo Sang Ick Park Hye-Ja Lee The discovery of metabolomics-based biomarkers has been a focus of recent kidney dysfunction research. In the present study, we aimed to identify metabolites associated with chronic kidney disease (CKD) in the...
Biomedicines, Vol. 8, Pages 224: HDX-MS: An Analytical Tool to Capture Protein Motion in Action Biomedicines doi: 10.3390/biomedicines8070224 Authors: Dominic Narang Cristina Lento Derek J. Wilson Virtually all protein functions in the cell, including pathogenic processes, require coordinated motion of atoms or domains, i.e., conformational dynamics. Understanding protein dynamics is therefore critical both for drug development and to learn about the underlying molecular causes...
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Biomolecules, Vol. 10, Pages 1076: The Long-Acting D3 Partial Agonist MC-25-41 Attenuates Motivation for Cocaine in Sprague-Dawley Rats Biomolecules doi: 10.3390/biom10071076 Authors: Gregory L. Powell Mark D. Namba Annika Vannan John Paul Bonadonna Andrew Carlson Rachel Mendoza Peng-Jen Chen Robert R. Luetdke Benjamin E. Blass Janet L. Neisewander The dopamine D3 receptor is a prime target for developing treatments for cocaine use disorders (CUDs). In this...
Biomolecules, Vol. 10, Pages 1075: Structural Elucidation of Irish Ale Bioactive Polar Lipids with Antithrombotic Properties Biomolecules doi: 10.3390/biom10071075 Authors: Alexandros Tsoupras Ronan Lordan Eoin O'Keefe Katie Shiels Sushanta Kumar Saha Ioannis Zabetakis The structures of bioactive polar lipids (PLs) of Irish ale with potent antithrombotic and cardioprotective properties were elucidated. Ale PL was fractionated by preparative thin layer chromatography (TLC)...
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