Κυριακή 19 Ιουλίου 2020


Reply to “Prior dual antiplatelet therapy and thrombolysis in acute stroke”
Annals of Neurology
Sat Jul 18, 2020 21:59
ANA Investigates: Embolic Stroke of Unknown Source Clinical Trials and Advances in Research
Annals of Neurology
Fri Jul 17, 2020 21:23
Cerebral hemorrhage in the LVAD patient: A case series and literature review
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Laura Ann Zima, Corinne Mayap Fotso, Viraj Parikh, Dallas Sheinberg, Michael Monterey, H Alex Choi, Ryan Kitagawa
Clinical Neurology and Neurosurgery
Sun Jul 19, 2020 14:57
Septic cavernous sinus thrombosis—Case series and review of the literature
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Bertie Geng, Xiao Wu, Ajay Malhotra
Clinical Neurology and Neurosurgery
Sun Jul 19, 2020 14:57
Evaluating the utility of fasting lipid panel in addition to random lipid panel in determining lipid-lowering therapy in acute ischemic stroke or TIA patients
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Usman Shehzad, Abhinay Tumati, Ruth A. Reinsel, Dharampreet Singh, Dazzle Dadra, Archana Purushotham, Jason Mathew
Clinical Neurology and Neurosurgery
Sat Jul 18, 2020 18:57
Low total cholesterol and high density lipoprotein are independent predictors of poor outcomes following aneurysmal subarachnoid hemorrhage: A preliminary report
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Boyi Li, Matthew McIntyre, Chirag Gandhi, Mohamed Halabi, Andrew Long, Alexander Van Hoof, Adil Afridi, Meic Schmidt, Chad Cole, Justin Santarelli, Fawaz Al-Mufti, Christian Bowers
Clinical Neurology and Neurosurgery
Sat Jul 18, 2020 18:57
Parkinson’s gait kinematics deteriorates across multiple cognitive domains under dual-task paradigms
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Amanda L. Penko, Matthew C. Streicher, Tanujit Dey, Anson B. Rosenfeldt, Jay L. Alberts
Clinical Neurology and Neurosurgery
Fri Jul 17, 2020 15:06
Clinical and economic burden of neurofibromatosis type 2 in the United States
Publication date: October 2020Source: Clinical Neurology and Neurosurgery, Volume 197Author(s): Andrew B. Koo, Jacky T. Yeung, Isaac G. Freedman, Jun Hui Lee, Osama M. Ahmed, Anthony K. Ma, Danielle F. Miyagishima, Michael DiLuna, Kristopher Kahle
Clinical Neurology and Neurosurgery
Fri Jul 17, 2020 15:06
Neural coordination of bilateral power and precision finger movements
Abstract The dexterity of hands and fingers is related to the strength of control by cortico‐motoneuronal connections which exclusively exist in primates. The cortical command is associated with a task‐specific, rapid proprioceptive adaptation of forces applied by hands and fingers to an object. This neural control differs between ‘power grip’ movements (e.g. reach and grasp of a cup) where hand and fingers act as a unity and ‘precision grip’ movements (e.g. picking up a raspberry) where fingers...
European Journal of Neuroscience
Sat Jul 18, 2020 12:30
Issue Information
European Journal of Neuroscience
Thu Jul 16, 2020 21:12
Issue Information
European Journal of Neuroscience
Thu Jul 16, 2020 21:08
Extracellular Matrix Remodeling with Stress and Depression: Studies in Human, Rodent, and Zebrafish Models
Abstract Emerging evidence suggests that extracellular matrix (ECM) alterations occur with stress. Specifically, increases in perineuronal net (PNN) deposition have been observed in rodents exposed to chronic corticosterone or persistent social defeat stress. The PNN is a specific form of ECM that is predominantly localized to parvalbumin (PV)‐expressing inhibitory interneurons where it modulates neuronal excitability and brain oscillations that are influenced by the same. Consistent with a role...
European Journal of Neuroscience
Thu Jul 16, 2020 11:40
The limited contribution of early visual cortex in visual working memory for surface roughness
Abstract Are visual representations in the human early visual cortex necessary for visual working memory (VWM)? Previous studies suggest that VWM is underpinned by distributed representations across several brain regions, including the early visual cortex. Notably, in these studies, participants had to memorize images under consistent visual conditions. However, in our daily lives, we must retain the essential visual properties of objects despite changes in illumination or viewpoint....
Experimental Brain Research
Sat Jul 18, 2020 03:00
Starting position effects in the measurement of the postural vertical for pusher behavior
Abstract Pusher behavior (PB) is a severe lateral postural disorder that involves a disturbed subjective postural vertical (SPV) in the frontal plane. SPV is measured by determining the mean value and standard deviation of several trials beginning on both the contralesional- and ipsilesional-tilted positions. However, the postural representation, when passively tilted to the contralesional versus ipsilesional position, is different between patients with and without PB. Therefore,...
Experimental Brain Research
Sat Jul 18, 2020 03:00
Time evolution of frontal plane dynamic balance during locomotor transitions of altered anticipation and complexity
Locomotor transitions between different ambulatory tasks are essential activities of daily life. During these transitions, biomechanics are affected by various factors such as anticipation, movement direction,...
Journal of NeuroEngineering and Rehabilitation - Latest Articles
Sat Jul 18, 2020 03:00
Walking with a powered ankle-foot orthosis: the effects of actuation timing and stiffness level on healthy users
In the last decades, several powered ankle-foot orthoses have been developed to assist the ankle joint of their users during walking. Recent studies have shown that the effects of the assistance provided by po...
Journal of NeuroEngineering and Rehabilitation - Latest Articles
Fri Jul 17, 2020 03:00
Relying on more sense for enhancing lower limb prostheses control: a review
Modern lower limb prostheses have the capability to replace missing body parts and improve the patients’ quality of life. However, missing environmental information often makes a seamless adaptation to transit...
Journal of NeuroEngineering and Rehabilitation - Latest Articles
Fri Jul 17, 2020 03:00
Challenges for biophysical modeling of microstructure
Publication date: Available online 18 July 2020Source: Journal of Neuroscience MethodsAuthor(s): Ileana O. Jelescu, Marco Palombo, Francesca Bagnato, Kurt G. Schilling
Journal of Neuroscience Methods
Sun Jul 19, 2020 15:30
Golgi staining-like retrograde labeling of brain circuits using rabies virus: Focus onto the striatonigral neurons
Publication date: Available online 18 July 2020Source: Journal of Neuroscience MethodsAuthor(s): P. Salin, D. Blondel, Goff L. Kerkerian-Le, P. Coulon
Journal of Neuroscience Methods
Sat Jul 18, 2020 19:39
Regional segmentation strategy for DTI analysis of human corpus callosum indicates motor function deficit in mild cognitive impairment
Publication date: Available online 17 July 2020Source: Journal of Neuroscience MethodsAuthor(s): Surya Rajan, Julia Brettschneider, Joanna F Collingwood, for the Alzheimer’s Disease Neuroimaging Initiative
Journal of Neuroscience Methods
Sat Jul 18, 2020 19:39
A kernel-based method to calculate local field potentials from networks of spiking neurons
Publication date: Available online 17 July 2020Source: Journal of Neuroscience MethodsAuthor(s): Bartosz Telenczuk, Maria Telenczuk, Alain Destexhe
Journal of Neuroscience Methods
Sat Jul 18, 2020 19:39
Heritability of Structural Patterning in the Human Cerebral Cortex
Publication date: Available online 18 July 2020Source: NeuroImageAuthor(s): Frithjof Kruggel, Ana Solodkin
NeuroImage
Sat Jul 18, 2020 14:27
Multi-dimensional connectivity: a conceptual and mathematical review
Publication date: Available online 17 July 2020Source: NeuroImageAuthor(s): Alessio Basti, Hamed Nili, Olaf Hauk, Laura Marzetti, Richard N. Henson
NeuroImage
Fri Jul 17, 2020 13:15
Manipulating the structure of natural scenes using wavelets to study the functional architecture of perceptual hierarchies in the brain
Publication date: Available online 17 July 2020Source: NeuroImageAuthor(s): Alexander M. Puckett, Mark M. Schira, Zoey J. Isherwood, Jonathan D. Victor, James A. Roberts, Michael Breakspear
NeuroImage
Fri Jul 17, 2020 13:15
Characterizing the analgesic effects of real and imagined acupuncture using functional and structure MRI
Publication date: Available online 17 July 2020Source: NeuroImageAuthor(s): Jin Cao, Yiheng Tu, Georgia Wilson, Scott P. Orr, Jian Kong
NeuroImage
Fri Jul 17, 2020 13:15
The neural basis of rapid unfamiliar face individuation with human intracerebral recordings
Publication date: Available online 17 July 2020Source: NeuroImageAuthor(s): Corentin Jacques, Bruno Rossion, Angélique Volfart, Hélène Brissart, Sophie Colnat-Coulbois, Louis Maillard, Jacques Jonas
NeuroImage
Fri Jul 17, 2020 13:15
Reduction of somatosensory functional connectivity by transcranial alternating current stimulation at endogenous mu-frequency
Publication date: Available online 17 July 2020Source: NeuroImageAuthor(s): Christopher Gundlach, Matthias M. Müller, Maike Hoff, Patrick Ragert, Till Nierhaus, Arno Villringer, Bernhard Sehm
NeuroImage
Fri Jul 17, 2020 13:15
Risk factors of cemented vertebral refracture after percutaneous vertebral augmentation: a systematic review and meta-analysis
Abstract To evaluate the risk factors of cemented vertebral refracture after percutaneous vertebral augmentation (PVA) for patients with osteoporotic vertebral compression fractures (OVCFs). We performed a literature search on cemented vertebral refracture after PVA using the PubMed, EMBASE, and Cochrane Library medical databases. The clinical data, including literature information, basic patient information, observational factors, and interventional factors, were extracted by...
Neuroradiology
Sat Jul 18, 2020 03:00
Multimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability
Abstract Purpose Circumferential enhancement on MR vessel wall imaging has been proposed as a biomarker of a higher risk of rupture in intracranial aneurysms. Focal enhancement is frequently encountered in unruptured aneurysms, but its implication for risk stratification and patient management remains unclear. This study investigates the association of focal wall enhancement with hemodynamic and morphological risk factors and histologic...
Neuroradiology
Fri Jul 17, 2020 03:00
Stroop N450 reflects both stimulus conflict and response conflict
N450 is described as a valid event-related potential indicator of Stroop interference, but the true specific psychological meaning of the Stroop N450 remains obscure. In the present research, we first used a Chinese character incongruent-eligible task and manipulated different types of conflict to investigate whether Stroop N450 reflects stimulus conflict, response conflict or both. The results showed that, only the N450 in the incongruent-eligible condition was more negative than that of the incongruent-ineligible...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Serotonin hyperpolarizes the dorsal raphe nucleus neurons of mice by activating G protein–coupled inward rectifier potassium channels
Serotonin (5-HT) has an important role in the pathophysiology of the mood disorders like major depression and anxiety disorders in central nervous system. On the one hand, dorsal raphe nucleus (DRN) neurons send serotonergic projections to almost all brain regions. On the other hand, they affect themselves through 5-HT1A autoreceptors. Many electrophysiological studies have investigated the ionic mechanism of the 5-HTs effect on the DRN neurons of the rat. However, there is no study characterizing...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Tea polyphenols protect learning and memory in sleep-deprived mice by promoting AMPA receptor internalization
Chronic sleep loss caused lots of health problems, also including cognition impairment. Tea is one of the most popular drinks when people stay up late. Nevertheless, the effects of tea on sleep deprivation-induced cognition impairment are still unclear. In the present study, we found 24-h sleep deprivation (S-DEP) increased membrane α-amino-3-hydroxy-5-methyl-4-isoxa-zolep-propionate (AMPA) receptor level through a tumor necrosis factor α (TNFα)-dependent pathway in hippocampi. Blocking elevated...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Magnesium sulfate ameliorates sepsis-induced diaphragm dysfunction in rats via inhibiting HMGB1/TLR4/NF-κB pathway
Background Diaphragm dysfunction could be induced by sepsis with subsequent ventilatory pump failure that is associated with local infiltration of inflammatory factors in the diaphragm. It has been shown that the administration of anticonvulsant agent, magnesium sulfate (MgSO4) could decrease systematic inflammatory response. We recently reported that MgSO4 could inhibit macrophages high mobility group box 1 (HMGB1) secretion that confirms its anti-inflammatory properties. Toll-like receptor 4...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Mechanisms of cross-modal selective attentional bias for negative faces of anger and disgust in high-trait anxiety individuals
Research reveals that selective attentional bias to socially negative information is a reliable characteristic of individuals with high-trait anxiety (HTA). However, for selective attentional bias across sensory channels (visual and auditory), the interaction between attentional bias type and negative face type remains unclear. In this study, we recruited 30 individuals with high- and low-trait anxiety (LTA) (15 in each group), and measured their engagement and disengagement bias indices using the...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Gesture style can affect the integration of gestures and speech: the evidence from Chinese ERP research
People often accompany gestures in the process of speaking, but the individual’s gesture style is not the same. The present study uses the ambiguity resolution paradigm to explore the influence of two kinds of gesture styles on gesture-verbal comprehension. The study manipulated the gesture styles and meaning types of target words and recorded N400 amplitude. This study found that (1) in the non-grooming condition, compared with the situation where the gesture and semantics are inconsistent, a smaller...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Relationship between symptom dimensions and white matter alterations in untreated patients with obsessive–compulsive disorder: a diffusion tensor imaging study
The aim of the study was explore how the white matter structure changes and obsessive–compulsive disorder (OCD) symptom dimensions are related. We recruited 46 untreated adult patients with OCD, and 46 healthy controls matched for gender, age, and education. The patients were classified according to symptom dimensions assessed by the four-factor model. Diffusion tensor imaging (DTI) was employed to evaluate brain structural alterations in patients with OCD, and DTI data were processed using voxel-based...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
microRNA-1906 protects cerebral ischemic injury through activating Janus kinase 2/signal transducer and activator of transcription 3 pathway in rats
This study aimed to investigate the effects of miR-1906 on cerebral ischemic injury and its underlying mechanisms. After 24 h of reperfusion, neurological deficit scores, brain water content and infarct volume were measured. Neuronal apoptosis was detected by using terminal dexynucleotidyl transferase-mediated dUTP nick end labeling assay. Hematoxylin–eosin staining was used to evaluate the histopathological damage of neurons. The expression of miR-1906 was detected by qRT-PCR. And the expressions...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Mental rotation of alphabet characters affects the face-sensitive N170 component
Face-sensitive N170 component of event-related potential is sensitive to face inversion, which has been defined as the face-inversion effect. Moreover, a previous study suggested that similar to the face-inversion effect of the face-sensitive N170 affected by mental rotation of the face, object-related N170 of three-dimensional objects was also affected by the mental rotation of two-dimensional objects. The purpose of the present study was to compare the relationship between face-sensitive N170 during...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
miR-187-3p participates in contextual fear memory formation through modulating SATB2 expression in the hippocampus
Purpose When threatened, fear is one of the most important responses that an organism exhibits. The mechanisms involved in forming fear memories include specific neurological structures, neural circuits and detailed molecular interactions. Methods MicroRNAs (miRNAs, small non-coding RNAs) act as endogenous functional small molecules that participate in or interfere with the formation of new fear memory by inhibiting the expression of mRNA targets. MicroRNA-187 (miR-187) is a newly reported...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Metabolic syndrome is associated with cognitive impairment after transient ischemic attack/mild stroke, but does not affect cognitive recovery in short term
The metabolic syndrome (MetS) is a cluster of risk factors for cognitive impairment. We aimed to investigate the association between MetS and risk of persistent cognitive impairment in patients with a transient ischemic attack (TIA) or mild ischemic stroke. This is a prospective and observational study in consecutive patients with first-ever TIA or mild stroke (National Institutes of Health Stroke Scale score ≤ 6). Patients underwent Montreal cognitive assessment (MoCA) at hospital admission and...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Ethanol antagonizes P2X4 receptors in ventral tegmental area neurons
P2X4 receptors are found throughout the central nervous system, and studies have shown that these purinergic receptors are important regulators of alcohol intake. The ventral tegmental area (VTA) is an important region for the rewarding and reinforcing properties of alcohol, but the role of P2X4 receptors in this region is unknown. Using both immunohistochemical and electrophysiological methods, we examined the interaction between P2X4 receptors and alcohol on VTA neurons. Incubation of brain slices...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Native expression of ASIC1a and ASIC1b human homologues in the HEK 293 cell line allows pharmacological evaluation of analgesics targeting acid sensation in humans
Nociceptors arising from the dorsal root ganglia (DRG) express acid-sensing ion channel-1 (ASIC1) subtypes to mediate the perception of inflammatory and neuropathic pain, and as such, these receptors are attractive targets for the development of analgesics for these painful conditions. Nevertheless, given that the human and rodent DRG differ considerably in subtype proportions of ASIC1 and that the pharmacological properties of rodent ASIC1 subtypes and their human homologues are distinct, ASIC1...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
β-amyloid-induced gonadotropin-releasing hormone decline involving Forkhead transcription factor FOXO3a and nuclear factor-κB
Previously, it has been demonstrated that aging is controlled by the hypothalamus, and that hypothalamus-driven programmatic aging is associated with nuclear factor-κB (NF-κB)-mediated gonadotropin-releasing hormone (GnRH) decrease. Abundant accumulation of β-amyloid (Aβ) has been observed in brains of cognitively normal elderly. However, it is unclear whether Aβ neurotoxicity is involved in aging-associated hypothalamic GnRH decline. GT1-7 cells, which are a cell line of hypothalamic GnRH neurons,...
NeuroReport - Current Issue
Fri Jul 17, 2020 21:52
Epilepsy surgery for Rasmussen encephalitis: the UCLA experience.
Epilepsy surgery for Rasmussen encephalitis: the UCLA experience. J Neurosurg Pediatr. 2020 Jul 17;:1-9 Authors: Bellamkonda N, Phillips HW, Chen JS, Tucker AM, Maniquis C, Mathern GW, Fallah A Abstract OBJECTIVE: Rasmussen encephalitis (RE) is a rare inflammatory neurological disorder typically involving one hemisphere and resulting in drug-resistant epilepsy and progressive neurological decline. Here, the authors present seizure outcomes...
Pediatric Neurosurgeons
Sat Jul 18, 2020 13:38
Defining the role of the condylar-C2 sagittal vertical alignment in Chiari malformation type I.
Defining the role of the condylar-C2 sagittal vertical alignment in Chiari malformation type I. J Neurosurg Pediatr. 2020 Jul 17;:1-6 Authors: Ravindra VM, Iyer RR, Awad AW, Bollo RJ, Zhu H, Brockmeyer DL Abstract OBJECTIVE: The authors' objective was to better understand the anatomical load-bearing relationship between the atlantooccipital joint and the upper cervical spine and its influence on the clinical behavior of patients with Chiari...
Pediatric Neurosurgeons
Sat Jul 18, 2020 13:38
Juvenile xanthogranuloma of the subdural spaces mimicking chronic hematoma with positive FDG uptake on PET: case report.
Juvenile xanthogranuloma of the subdural spaces mimicking chronic hematoma with positive FDG uptake on PET: case report. J Neurosurg Pediatr. 2020 Jul 17;:1-5 Authors: Kahn JA, Waltz JT, Eskandari RM, Welsh CT, Antonucci MU Abstract The authors report an unusual presentation of juvenile xanthogranuloma (JXG), a non-Langerhans cell histiocytosis of infancy and early childhood. This entity typically presents as a cutaneous head or neck nodule...
Pediatric Neurosurgeons
Sat Jul 18, 2020 13:38
Reliability of the radiopharmaceutical shunt flow study for the detection of a CSF shunt malfunction in the presence of stable ventricular size.
Reliability of the radiopharmaceutical shunt flow study for the detection of a CSF shunt malfunction in the presence of stable ventricular size. J Neurosurg Pediatr. 2020 Jul 17;:1-7 Authors: Quezada JJ, McComb JG Abstract OBJECTIVE: The authors sought to determine the reliability of a radiopharmaceutical (RP) shunt flow study for the detection of a CSF-diverting shunt malfunction in the presence of stable ventricular size. METHODS:...
Pediatric Neurosurgeons
Sat Jul 18, 2020 13:38
Head of bed elevation in pediatric patients with severe traumatic brain injury.
Head of bed elevation in pediatric patients with severe traumatic brain injury. J Neurosurg Pediatr. 2020 Jul 17;:1-11 Authors: Lang SS, Valeri A, Zhang B, Storm PB, Heuer GG, Leavesley L, Bellah R, Kim CT, Griffis H, Kilbaugh TJ, Huh JW Abstract OBJECTIVE: Head of bed (HOB) elevation to 30° after severe traumatic brain injury (TBI) has become standard positioning across all age groups. This maneuver is thought to minimize the risk of elevated...
Pediatric Neurosurgeons
Sat Jul 18, 2020 13:38
Corrigendum to “Effects of anti-rVEGF on the expression of VEGF receptor-2 and P2X2/3 receptors of the spinal dorsal horn in neuropathic pain rats” [Brain Res. Bull. 87 (2-3 February) (2012), 227–233]
Publication date: Available online 18 July 2020Source: Brain Research BulletinAuthor(s): Xin Li, Guilin Li, Hong Xu, Xiaoli Tang, Yun Gao, Changshui Xu, Shuangmei Liu, Jinyan Xie, Guihua Tu, Haiying Peng, Shuyi Qiu, Shangdong Liang
ScienceDirect Publication: Brain Research Bulletin
Sun Jul 19, 2020 22:44
Corrigendum to “Effect of puerarin on P2X3 receptor involved in hyperalgesia after burn injury in the rat” [Brain Res. Bull. 80 (December (6)) (2009) 341–346]
Publication date: Available online 18 July 2020Source: Brain Research BulletinAuthor(s): Changshui Xu, Guilin Li, Yun Gao, Shuangmei Liu, Jiari Lin, Jun Zhang, Xin Li, Han Liu, Shangdong Liang
ScienceDirect Publication: Brain Research Bulletin
Sun Jul 19, 2020 22:44
Long-term metformin therapy improves neurobehavioral functions and antioxidative activity after cerebral ischemia/reperfusion injury in rats
Publication date: Available online 18 July 2020Source: Brain Research BulletinAuthor(s): Iman Fatemi, Pooya Saeed-Askari, Elham Hakimizadeh, Ayat Kaeidi, Sogand Esmaeil-Moghaddam, Mohammad Pak-Hashemi, Mohammad Allahtavakoli
ScienceDirect Publication: Brain Research Bulletin
Sun Jul 19, 2020 22:44
Retraction notice to “The antidepressant effects of L-arginine on chronic mild stress-induced depression by augmenting the expression of brain-derived neurotrophic factor in rats” [Brain Res. Bull. 158 (May) (2020) 128–134]
Publication date: Available online 17 July 2020Source: Brain Research BulletinAuthor(s): Dan Dong, Ting Lei, Meiying Song, Lijiang Ma, Hua Zhao
ScienceDirect Publication: Brain Research Bulletin
Sat Jul 18, 2020 14:37
Astrocyte-derived exosome-transported microRNA-34c is neuroprotective against cerebral ischemia/reperfusion injury via TLR7 and the NF-κB/MAPK pathways
Publication date: Available online 16 July 2020Source: Brain Research BulletinAuthor(s): Weicheng Wu, Jiaquan Liu, Chengbin Yang, Zihui Xu, Jianbao Huang, Jiyan Lin
ScienceDirect Publication: Brain Research Bulletin
Fri Jul 17, 2020 14:22
Automated segmentation of baseline metabolic total tumor burden in diffuse large B-cell lymphoma: which method is most successful ?
Introduction: Metabolic tumor volume (MTV) is a promising biomarker of pretreatment risk in diffuse large B-cell lymphoma (DLBCL). Different segmentation methods can be used which predict prognosis equally well but give different optimal cut-offs for risk stratification. Segmentation can be cumbersome meaning a fast, easy and robust method is needed. Aims were to i) evaluate the best automated MTV workflow in DLBCL ii) determine if uptake time, (non)compliance with standardized recommendations...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Molecular Imaging of Very Late Antigen-4 (VLA-4) in Acute Lung Injury
Inflammation plays a central role in the pathogenesis of acute lung injury (ALI) during both the acute pneumonitis stage and the progression into the chronic fibroproliferative phase, leading to pulmonary fibrosis. Currently, there is an unmet clinical and research need for non-invasive approaches to monitor lung inflammation through targeting immunoregulatory pathways contributing to ALI pathogenesis. In this study, we evaluated the role of targeted imaging of very late antigen-4 (VLA-4), as a key...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Fluorescence-guided visualization of soft tissue sarcomas by targeting vascular endothelial growth factor-A: a phase 1 single-center clinical trial
Rationale: Resection of soft tissue sarcomas (STS) is accompanied by a high rate of tumor-positive surgical margins (14-34%), which potentially leads to decreased disease-free survival. Vascular Endothelial Growth Factor-A (VEGF-A) is overexpressed in malignant tumors, including STS, and can be targeted with bevacizumab-800CW during fluorescence-guided surgery for real-time tumor detection. In this phase 1 clinical trial, we determined the feasibility, safety and optimal dose of bevacizumab-800CW...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
A microdosing study with 99mTc-PHC-102 for the SPECT/CT imaging of primary and metastatic lesions in renal cell carcinoma patients
99mTc-PHC-102 is a 99mTc-labeled derivative of acetazolamide, a high-affinity small organic ligand of Carbonic Anhydrase IX (CAIX). 99mTc-PHC-102 has previously shown favourable in vivo biodistribution properties in mouse models of CAIX-positive clear cell renal cell carcinoma (ccRCC) and colorectal cancer. In this study, we aimed to explore the targeting performance of 99mTc-PHC-102 in single-photon emission computed tomography (SPECT) in patients with RCC, while also assessing the safety and tolerability...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Non-displaceable binding is a potential confounding factor in 11CPBR28 TSPO PET studies
The positron emission tomography (PET) ligand 11C-PBR28 binds to the 18kDa translocator protein (TSPO), a biomarker of glia. In clinical studies of TSPO, the ligand total distribution volume, VT, is frequently the reported outcome measure. Since VT is the sum of the ligand specific (VS) and non-displaceable binding (VND), differences in VND across subjects and groups will have an impact on VT. Methods: Here, we used a recently developed method for simultaneous estimation of VND (SIME) to disentangle...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Diagnostic performance of pulmonary embolism imaging in patients with history of asthma
Asthma and pulmonary embolism (PE) can present with overlapping symptoms, and distinguishing between these two conditions can be challenging. Asthma may limit imaging for PE due to either worsened ventilation defects on ventilation/perfusion scan (VQ) or increased motion artifact on CT pulmonary angiography (CTPA). Methods: We identified adults evaluated for PE with VQ or CTPA from 2012-2016. Patients with chronic lung disease (other than asthma) were excluded. Studies were classified as negative,...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Head-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer
Invasive lobular carcinoma (ILC) demonstrates lower conspicuity on 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) PET than the more common invasive ductal carcinoma (IDC). Other molecular imaging methods may be needed for evaluation of this malignancy. As ILC is nearly always (95%) estrogen receptor (ER) positive, ER-targeting PET tracers such as 16α-[18F]-fluoroestradiol ([18F]FES) may have value. We reviewed prospective trials at Memorial Sloan Kettering Cancer Center (MSK) utilizing [18F]FES PET/CT...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Oncology-inspired treatment options for COVID-19
Rationale: CR3022 is a human antibody which binds to the SARS-CoV-2 virus. Here, we explore the use of CR3022 as a molecularly targeted radiotherapeutic. Methods: CR3022 was labeled with Iodine-131 using the Iodogen-method and purified, yielding 131I-CR3022. Using a magnetic bead assay and a recombinant SARS-CoV-2 spike protein fragment, we tested binding of 131I-CR3022 in the presence and absence of CR3022. Results: We conjugated the antibody CR3022 with a purity > 98% and a molar activity...
The Journal of Nuclear Medicine (JNM)
Fri Jul 17, 2020 23:29
Two Cases of Posterior Cerebral Artery P2 Segment Occlusion with Motor Weakness Improved by Acute Mechanical Thrombectomy
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Hidekazu Yamazaki, Masafumi Morimoto, Chiyoe Hikita, Mitsuhiro Iwasaki, Maeda Masahiro, Yasufumi Inaka, Shinya Fukuta, Hiroaki Sato, Jyunpei Nagasawa
World Neurosurgery
Sun Jul 19, 2020 14:25
Expanded Endoscopic Endonasal Approach for Removal of a Tuberculum Sella Meningioma
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Aristotelis Kalyvas, João Paulo Almeida, Nilesh Mohan, Philip J. O'Halloran, Allan Vescan, Fred Gentili
World Neurosurgery
Sun Jul 19, 2020 14:25
Overview of Minimally Invasive Spine Surgery
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Parthik D. Patel, Jose A. Canseco, Nathan Houlihan, Alyssa Gabay, Giovanni Grasso, Alexander R. Vaccaro
World Neurosurgery
Sun Jul 19, 2020 14:25
Impact of Resident Participation During Surgery on Neurosurgical Outcomes: A Meta-Analysis
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Shivani Baisiwala, Nathan A. Shlobin, Michael B. Cloney, Nader S. Dahdaleh
World Neurosurgery
Sun Jul 19, 2020 14:25
Percutaneous Fenestration of a Spinal Arachnoid Web Using an Intrathecal Catheter: Effect on Cerebrospinal Fluid Flow and Clinical Status
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Adnan I. Qureshi, Navpreet K. Bains, Vamshi K.S. Balasetti, Karim Salame, Camilo R. Gomez, Farhan Siddiq, Joseph P. Cousins
World Neurosurgery
Sun Jul 19, 2020 14:25
First-Onset Hypokalemic Periodic Paralysis Following Surgery for Myxopapillary Ependymoma
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Adrian Balasa, Flaviu Tamas, Corina Hurghis, Smaranda Maier, Anca Motataianu, Rares Chinezu
World Neurosurgery
Sun Jul 19, 2020 14:25
Lead Toxicity From Intradiscal Retained Bullet Fragment: Management Considerations and Recommendations
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): James E. Towner, Thomas A. Pieters, Paul K. Maurer
World Neurosurgery
Sun Jul 19, 2020 14:25
Intraparenchymal Epidermoid Cyst Close to Broca Area—Awake Craniotomy and Gross Total Resection
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Leonardo J.M. de Macêdo Filho, Gilnard C.M. Aguiar, Fátima C. Pessoa, Gabryella S. Diógenes, Felipe S. Borges, Andrei F. Joaquim, Lucas Alverne Freitas de Albuquerque
World Neurosurgery
Sun Jul 19, 2020 14:25
Embolic Agents and Microcatheters for Endovascular Treatment of Cerebral Arteriovenous Malformations
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Matthew J. Triano, Jacques Lara-Reyna, Alexander J. Schupper, Kurt A. Yaeger
World Neurosurgery
Sun Jul 19, 2020 14:25
Clinical Features and Outcomes of Primary Spinal Cord Glioblastoma: a Single Center Experience and Literature Review
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Kaiyuan Yang, Weitao Man, Linkai Jing, Zhenxing Sun, Ping Liang, James Wang, Guihuai Wang
World Neurosurgery
Sun Jul 19, 2020 14:25
Outpatient vs Inpatient Posterior Lumbar Fusion (PLF) for Low-Risk Patients: An Analysis of Thirty-Day Outcomes from the National Surgical Quality Improvement Program (NSQIP)
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Elena Blaginykh, Mohammed Ali Alvi, Anshit Goyal, Yagiz Ugur Yolcu, Panagiotis Kerezoudis, Arjun S. Sebastian, Mohamad Bydon
World Neurosurgery
Sun Jul 19, 2020 14:25
Neuroenteric cyst masquerading as acute flaccid paralysis in a 2month old infant
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Sushanta K. Sahoo, Pravin Salunke, Manjinder singh Randhawa, Pragna HC, Debajyoti Chatterjee, ohn Vimal Vincent
World Neurosurgery
Sun Jul 19, 2020 14:25
Long-term outcomes of excision surgery for aggressive vertebral hemangiomas
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Makoto Handa, Satoru Demura, Satoshi Kato, Kazuya Shinmura, Noriaki Yokogawa, Noritaka Yonezawa, Takaki Shimizu, Norihiro Oku, Ryo Kitagawa, Ryohei Annen, Hideki Murakami, Norio Kawahara, Hiroyuki Tsuchiya
World Neurosurgery
Sun Jul 19, 2020 14:25
Necessity of Direct Decompression for Thoracolumbar Junction Burst Fractures with Neurologic Compromise
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Nitin K. Jaiswal, Vishal Kumar, Varun Puvanesarajah, Ashish Dagar, Mahesh Prakash, Mandeep Dhillon, Sarvdeep S. Dhatt
World Neurosurgery
Sun Jul 19, 2020 14:25
Neurological examination, rather than vascular risk factor assessment, serves to distinguish strokes from stroke mimics
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Jessica E. Marot, Tania Rebeiz, Christopher Kramer, Cedric McKoy, James Brorson, Fernando Goldenberg, Ava L. Liberman, Seon-Kyu Lee
World Neurosurgery
Sun Jul 19, 2020 14:25
Extensive pneumorrhachis after spontaneous pneumomediastinum : A case report
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Kerri Bally, Scott Leikin, Konstantinos Margetis, Alexandra S. Reynolds
World Neurosurgery
Sun Jul 19, 2020 14:25
COVID-19 and Neurosurgery Residency Action Plan: An Institutional Experience from the United States of America
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): David T. Fernandes Cabral, Nima Alan, Nitin Agarwal, Dade Lunsford, Edward A. Monaco
World Neurosurgery
Sun Jul 19, 2020 14:25
Emerging Trends in the Neurosurgical Workforce of Low- and Middle-Income Countries: A cross-sectional study
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Ulrick Sidney Kanmounye, Jean Wilguens Lartigue, Samantha Sadler, Ho Kei Yuki Ip, Jacquelyn Corley, Miguel Angel Arraez, Kee Park
World Neurosurgery
Sun Jul 19, 2020 14:25
Endovascular and Surgical Treatment is Predictive of Readmission Risk After Aneurysmal Subarachnoid Hemorrhage
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Ajay Chatrath, Sauson Soldozy, Jennifer D. Sokolowski, Rebecca M. Burke, Julianne G. Schultz, Zuseen C. Rannigan, Min S. Park
World Neurosurgery
Sun Jul 19, 2020 14:25
The Microscopic and Endoscopic Skull Base Approaches Hands-On Cadaver Course at 30: a Historical Vignette
Publication date: Available online 18 July 2020Source: World NeurosurgeryAuthor(s): Mirza Pojskić, Orhan Čustović, Karen Hutsel Erwin, Ian F. Dunn, Mark Eisenberg, Andrew J. Gienapp, Kenan I. Arnautović
World Neurosurgery
Sun Jul 19, 2020 14:25
Rescue Surgery in the Flow Diverter Era: Partial Trapping plus Revascularization Technique for a Giant Carotid-Ophthalmic Aneurysm.
Publication date: Available online 17 July 2020Source: World NeurosurgeryAuthor(s): Ramon Torné, Ana Rodríguez-Hernández, Ana Tercero-Uribe, Paola Hurtado, Antonio López-Rueda, Jose Poblete, Joaquim Enseñat
World Neurosurgery
Sun Jul 19, 2020 14:25
Spontaneous Resolution of Dural and Pial Arteriovenous Fistulae Arising after Superficial Temporal Artery to Middle Cerebral Artery Bypass for Moyamoya Disease
Publication date: Available online 17 July 2020Source: World NeurosurgeryAuthor(s): Sophie M. Peeters, Geoffrey P. Colby, Elnaz Guivatchian, Matthew Z. Sun, Satoshi Tateshima, Anthony C. Wang
World Neurosurgery
Sun Jul 19, 2020 14:25
Technical Consideration of endoscopic lumbar decompression.
Publication date: Available online 17 July 2020Source: World NeurosurgeryAuthor(s): Chul-Woo Lee, Kang-Jun Yoon
World Neurosurgery
Sun Jul 19, 2020 14:25
Diffuse Neuritis Ossificans of the Brachial Plexus: Case Report and Review of the Literature
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Nikhil K. Murthy, Karen J. Fritchie, Kimberly K. Amrami, Peter S. Rose, Robert J. Spinner
World Neurosurgery
Sat Jul 18, 2020 18:27
Neurocysticercosis Presenting as an Isolated Suprasellar Lesion
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): M. Harrison Snyder, Alexandria C. Marino, Matthew J. Shepard, Peggy Amoakohene, Debra M. Berry, Sugoto Mukherjee, Jose L. Mattos, John A. Jane
World Neurosurgery
Sat Jul 18, 2020 18:27
Transforaminal Endoscopic Approach for Large-Sample Tumor Biopsy using Beveled Working Channel for Core Technique: A Technical Note
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Sanjay Konakondla, Nelson Sofoluke, Jimmy Xia, Ryan Grant, Albert E. Telfeian, Christoph P. Hofstetter, Jonathan R. Slotkin
World Neurosurgery
Sat Jul 18, 2020 18:27
Tension Pneumocephalus from Positive Pressure Ventilation Following Endoscopic Skull Base Surgery: Case Series and an Institutional Protocol for the Management of Postoperative Respiratory Distress
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Mendel Castle-Kirszbaum, Yi Yuen Wang, James King, Brent Uren, Martin Kim, R. Andrew Danks, Tony Goldschlager
World Neurosurgery
Sat Jul 18, 2020 18:27
Detection of Transient Increase of Cerebral Blood Flow and Reversible Neuronal Dysfunction by Iodine-123-Iomazenil Single Photon Emission Computed Tomography After Cerebral Hyperperfusion Syndrome After Revascularization Surgery for Moyamoya Disease
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Mami Yamasaki, Hideyuki Yoshioka, Kazuya Kanemaru, Takashi Yagi, Koji Hashimoto, Nobuo Senbokuya, Hiroyuki Kinouchi
World Neurosurgery
Fri Jul 17, 2020 21:40
Cerebellar Neurocytoma with Excellent Response to Radiotherapy
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Siwei Chen, Hongzhou Duan, Ran Liu, Jingjing Luo, Hui Wang, Shuang Zhang, Haiqiang Jin, Jing Bai, Feng Gao, Guiping Zhao, Yining Huang
World Neurosurgery
Fri Jul 17, 2020 21:40
Perineural Spread of Clear Cell Adenocarcinoma of Müllerian Origin Resulting in Neoplastic Lumbosacral Plexopathy
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Nikhil K. Murthy, Charles D. Sturgis, Kimberly K. Amrami, Robert J. Spinner
World Neurosurgery
Fri Jul 17, 2020 21:40
Radiation-Induced Spinal Cord Cavernous Malformations Associated with Medulloblastoma: Case Report and Review of the Literature
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Masahiro Oishi, Hironori Fujisawa, Katsuhiro Tsuchiya, Yoshio Nakajima
World Neurosurgery
Fri Jul 17, 2020 21:40
Minimally Invasive Parafascicular Surgical Approach for the Management of a Pediatric Third Ventricular Ependymoma: Case Report and Review of Literature
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Srikant S. Chakravarthi, Leah Lyons, Marian Bercu, Justin A. Singer
World Neurosurgery
Fri Jul 17, 2020 21:40
Headache and Dural Enhancement: Two Case Studies of Different Treatable Pathologies
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Umberto Pensato, Matteo Benini, Viscardo Paolo Fabbri, Patrizia Avoni, Maria Pia Foschini, Giovanni Rizzo, Rocco Liguori
World Neurosurgery
Fri Jul 17, 2020 21:40
Updates in Chronic Subdural Hematoma: Epidemiology, Etiology, Pathogenesis, Treatment, and Outcome
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): James Feghali, Wuyang Yang, Judy Huang
World Neurosurgery
Fri Jul 17, 2020 21:40
Concomitant Sacral Dural Arteriovenous Fistula and Conus Medullaris Arteriovenous Malformation with Respective Drainage Veins: Case Report and Literature Review
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Xiaodong Niu, Yanming Ren, Jin Li
World Neurosurgery
Fri Jul 17, 2020 21:40
Acute Deterioration in a Patient with Bilateral Chronic Subdural Hematomas Associated with Intracranial Hypotension Treated with an Epidural Blood Patch
Publication date: September 2020Source: World Neurosurgery, Volume 141Author(s): Keita Matsuoka, Eiichi Nakai, Yu Kawanishi, Tomonori Kadota, Hitoshi Fukuda, Tetsuya Ueba
World Neurosurgery
Fri Jul 17, 2020 21:40

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