Abstract A major challenge for electroencephalograph (EEG) studies on pediatric populations is that large amounts of data are lost due to artifacts (e.g., movement and blinks). Independent component analysis (ICA) can separate artifactual and neural activity, allowing researchers to remove such artifactual activity and retain a greater percentage of EEG data for analyses. However, manual identification of artifactual components is time‐consuming and requires subjective judgment. Automated algorithms,...
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Multiple organ failure and early surgery are associated with high morbimortality after open necrosectomy. Data are mostly derived from historical cohorts with early necrosectomy bereft of step-up treatment alg...
Tue Mar 17, 2020 02:00
Related ArticlesBirt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature. BMC Med Genet. 2020 Mar 14;21(1):52 Authors: Balsamo F, Cardoso PAS, do Amaral Junior SA, Theodoro TR, de Sousa Gehrke F, da Silva Pinhal MA, Bianco B, Waisberg J Abstract BACKGROUND: Birt-Hogg-Dubé syndrome (BHDS) is a rare autosomal dominant genodermatosis characterized by benign growth of the hair...
Tue Mar 17, 2020 12:03
Related ArticlesMetastatic serous borderline tumor with micro-invasive ovarian carcinoma presenting as a breast lump: A case report. Medicine (Baltimore). 2020 Feb;99(9):e19383 Authors: Dong F, Xie X, Wei X, Jiao MM, Duan J, Pan L, Bi L, Fan Z, Yang M Abstract RATIONALE: Breast metastasis from serous borderline tumor with micro-invasive carcinoma of ovary is a very rare condition. The breast lump as the only clinical presentation is rarely seen in ovarian...
Tue Mar 17, 2020 12:03
Related ArticlesIntralobar pulmonary sequestration with cystic degeneration mimicking a bronchogenic cyst in an elderly patient: A case report and literature review. Medicine (Baltimore). 2020 Feb;99(9):e19347 Authors: Kim HJ, Shin KE, Park JS, Lee H, Lee JW, Chin S, Shin HK Abstract INTRODUCTION: Pulmonary sequestration (PS) is a rare congenital malformation defined as nonfunctioning lung tissue supplied by systemic circulation. It is uncommonly diagnosed...
Tue Mar 17, 2020 12:03
Related ArticlesThe epithelioid gastrointestinal stromal tumor with pulmonary metastasis: A rare case report and literature review. Medicine (Baltimore). 2020 Feb;99(9):e19346 Authors: Xu D, Lin X, Qiu X Abstract RATIONALE: Available literature states that the histological subtype of the gastrointestinal stromal tumor (GIST) with pulmonary metastasis is often spindle cell type. To our knowledge, this is the first report of the GIST with pulmonary metastasis...
Tue Mar 17, 2020 12:03
Related ArticlesTwo cases of Hemosuccus pancreaticus after stereotactic radiotherapy to the pancreas: A case study. Cancer Radiother. 2020 Feb;24(1):60-63 Authors: Pezzulla D, Loi M, Suker M, van Eijck C, Nuyttens J Abstract Hemosuccus Pancreaticus (HP) is a very rare upper gastro-intestinal haemorrhagic event whose causes can be aneurismal lesions, acute and chronic pancreatic inflammatory conditions, and pancreatic masses. We present 2 cases of patients...
Tue Mar 17, 2020 12:03
Related ArticlesIsolated unilateral sixth nerve palsy in a patient with nasopharyngeal carcinoma. Rom J Ophthalmol. 2019 Oct-Dec;63(4):375-378 Authors: Aghdam KA, Zand A, Sanjari MS Abstract Objective: To describe an isolated unilateral sixth nerve palsy, as a rare neuro-ophthalmic presentation of nasopharyngeal carcinoma. Methods: We report a 54-year-old female, known case of nasopharyngeal carcinoma who was treated with chemo-radiotherapy, and presented...
Tue Mar 17, 2020 12:03
Related ArticlesEfficient recruitment of c-FLIPL to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma. Cancer Sci. 2020 Mar;111(3):807-816 Authors: Masuda A, Isobe Y, Sugimoto K, Yoshimori M, Arai A, Komatsu N Abstract Activation-induced cell death (AICD) mediated by the Fas/Fas ligand (FasL) system plays a key role in regulating immune response. Although normal natural killer (NK) cells use this system for...
Tue Mar 17, 2020 12:03
Related ArticlesMetabolic impact of pheochromocytoma/paraganglioma: targeted metabolomics in patients before and after tumor removal. Eur J Endocrinol. 2019 Dec;181(6):647-657 Authors: Erlic Z, Kurlbaum M, Deutschbein T, Nölting S, Prejbisz A, Timmers H, Richter S, Prehn C, Weismann D, Adamski J, Januszewicz A, Reincke M, Fassnacht M, Robledo M, Eisenhofer G, Beuschlein F, Kroiss M Abstract Objective: Excess catecholamine release by pheochromocytomas...
Tue Mar 17, 2020 12:03
Related ArticlesIncidence of isolated para-aortic lymph node metastasis in early stage endometrial cancer. Eur J Obstet Gynecol Reprod Biol. 2019 Nov;242:43-46 Authors: Nasioudis D, Holcomb K Abstract OBJECTIVE: To investigate the incidence of isolated para-aortic lymph node (PaLN) metastasis among patients with stage I endometrial cancer and negative pelvic lymph nodes. METHODS: The National Cancer Database was accessed and patients diagnosed...
Tue Mar 17, 2020 12:03
Related ArticlesCediranib phase-II study in children with metastatic alveolar soft-part sarcoma (ASPS). Pediatr Blood Cancer. 2019 12;66(12):e27987 Authors: Cohen JW, Widemann BC, Derdak J, Dombi E, Goodwin A, Dompierre J, Onukwubiri U, Steinberg SM, O'Sullivan Coyne G, Kummar S, Chen AP, Glod J Abstract BACKGROUND: Alveolar soft-part sarcoma (ASPS), a rare vascular sarcoma with a clinically indolent course, frequently presents with metastases. Vascular...
Tue Mar 17, 2020 12:03
Related ArticlesClinical and neuropsychological outcome of pediatric non-midline central nervous system germinoma treated with chemotherapy and reduced dose/volume irradiation: The Children's Hospital Los Angeles experience. Pediatr Blood Cancer. 2019 12;66(12):e27983 Authors: Yeo KK, Kayser K, Margol AS, Wong KK, Robison N, Finlay J, Dhall G Abstract BACKGROUND: Germ cell tumors (GCT) arising from non-midline structures (basal ganglia, thalamus, and...
Tue Mar 17, 2020 12:03
Related ArticlesAsbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register. Environ Health. 2019 08 30;18(1):78 Authors: Vimercati L, Cavone D, Delfino MC, De Maria L, Caputi A, Ferri GM, Serio G Abstract BACKGROUND: Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare disease with a poor prognosis. The diagnosis and management...
Tue Mar 17, 2020 12:03
Related ArticlesTrimodality therapy for atypical teratoid/rhabdoid tumor is associated with improved overall survival: A surveillance, epidemiology, and end results analysis. Pediatr Blood Cancer. 2019 12;66(12):e27969 Authors: Quinn TJ, Almahariq MF, Siddiqui ZA, Thompson AB, Hamstra DA, Kabolizadeh P, Gowans KL, Chen PY Abstract BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RTs) are rare aggressive central nervous system tumors. The use of radiation...
Tue Mar 17, 2020 12:03
Related ArticlesOsteoclast-like Giant Cell-type Pancreatic Anaplastic Carcinoma Presenting with a Duodenal Polypoid Lesion. Intern Med. 2019 Dec 15;58(24):3545-3550 Authors: Matsubayashi H, Kaneko J, Sato J, Satoh T, Ishiwatari H, Sugiura T, Ashida R, Uesaka K, Sasaki K, Ono H Abstract Osteoclast-like giant cell-type (OCGC) anaplastic carcinoma is a rare variant of pancreatic ductal adenocarcinoma, and its imaging characteristics and progression pattern...
Tue Mar 17, 2020 12:03
Related ArticlesFirst Drug Approved for Children with Rare Autoimmune Disorder. Am J Nurs. 2019 09;119(9):23 Authors: Aschenbrenner DS PMID: 31449118 [PubMed - indexed for MEDLINE]
Tue Mar 17, 2020 12:03
Related ArticlesCongenital cutaneous peripheral primitive neuroectodermal tumor/Ewing sarcoma: A rare case in a male neonate. Pediatr Blood Cancer. 2019 12;66(12):e27958 Authors: Lv M, Shen L, Li J, Xie Y, Wei L PMID: 31429518 [PubMed - indexed for MEDLINE]
Tue Mar 17, 2020 12:03
Related ArticlesSecondary cytoreductive surgery in recurrent uterine leiomyosarcoma: a multi-institutional study. Int J Gynecol Cancer. 2019 09;29(7):1134-1140 Authors: Bizzarri N, Ghirardi V, Di Fiore GLM, De Iaco P, Gadducci A, Casarin J, Perrone AM, Pasciuto T, Scambia G, Fagotti A Abstract INTRODUCTION: Uterine leiomyosarcoma (uLMS) represents a rare gynecological malignancy with high incidence of recurrence. Evidence in literature about the management...
Tue Mar 17, 2020 12:03
Related ArticlesEtiological distribution and clinical features of fever of unknown origin with pulmonary lesions in South China. Clin Respir J. 2019 Nov;13(11):683-692 Authors: Jiang Y, Zhuo C, Huang J, Tan Y, Guan Y Abstract INTRODUCTION: Fever of unknown origin (FUO) with pulmonary lesions is a common syndrome in respiratory diseases, which can be caused by infection, cancer, connective tissue disease and other rare diseases of South China. In patients...
Tue Mar 17, 2020 12:03
Related ArticlesMendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. Br J Cancer. 2019 07;121(2):180-192 Authors: Qian F, Rookus MA, Leslie G, Risch HA, Greene MH, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Andrulis IL, Arnold N, Arun BK, Ausems MGEM, Azzollini J, Barrowdale D, Barwell J, Benitez J, Białkowska K, Bonadona V, Borde J, Borg A, Bradbury AR, Brunet...
Tue Mar 17, 2020 12:03
Related Articles[Carcinoma cuniculatum: An unusual oral tumor]. Ann Pathol. 2019 Sep;39(5):369-373 Authors: Ben Arfi K, Marchal A, Hafian H, Boulagnon-Rombi C Abstract We report on a case of carcinoma cuniculatum (CC) of the maxillary gingival mucosa. A 60-year-old woman presented with an exophytic gingivo-palatal mass with slow growth and osteolytic evolution. A first performed biopsy was negative for malignancy. The diagnosis of CC was established...
Tue Mar 17, 2020 12:03
Related Articles[SCCOHT/ovarian rhabdoid tumor: A case report]. Ann Pathol. 2019 Sep;39(5):357-363 Authors: Bourgoin R, Cornelis F, Masliah-Planchon J, Genestie C, Laé M Abstract We report the case of a 22-year-old patient with acute abdominopelvic pain. The diagnosis of hypercalcemic small cell carcinoma (SCCOHT)/ovarian rhabdoid tumor has been made. Small cell carcinoma of hypercalcemic type is a rare and aggressive tumor that occurs in young women....
Tue Mar 17, 2020 12:03
Related Articles[Report of a mucoepidermoid breast carcinoma: Presentation of a rare entity]. Ann Pathol. 2019 Sep;39(5):364-368 Authors: Brunac AC, Caverivière P, Figurelli J, Siegfried-Vergnon A, Uro-Coste E, Lacroix-Triki M, Duprez-Paumier R Abstract Salivary gland-like tumours are described in the breast but remain very rare and difficult to diagnose in this location. Only 37 cases of mucoepidermoid carcinoma have been described in the literature....
Tue Mar 17, 2020 12:03
Related Articles[Meningeal melanoma arising from a preexisting meningeal melanocytoma: A clinical, pathological and cytogenetic study about one case]. Ann Pathol. 2019 Sep;39(5):352-356 Authors: Bourhis A, Quintin-Roué I, Redon S, Bourhis M, Magro E, Seizeur R, Marcorelles P, Uguen A Abstract Meningeal melanocytic tumors are rare. We report an exceptional case of transformation of a meningeal melanocytoma in a malignant melanoma. The course of the disease...
Tue Mar 17, 2020 12:03
Related ArticlesManagement of choroid plexus tumors-an institutional experience. Acta Neurochir (Wien). 2019 04;161(4):745-754 Authors: Hosmann A, Hinker F, Dorfer C, Slavc I, Haberler C, Dieckmann K, Knosp E, Czech T Abstract BACKGROUND: Choroid plexus tumors are rare entities. Resection is the mainstay of treatment in grade I and grade II tumors and adjuvant treatment is usually reserved for the less frequent choroid plexus carcinoma (CPC). Outcome...
Tue Mar 17, 2020 12:03
Intraoral Cutaneous Hamartomas-Clinicopathologic and Immunohistochemical Characteristics of 3 Cases.
Related ArticlesIntraoral Cutaneous Hamartomas-Clinicopathologic and Immunohistochemical Characteristics of 3 Cases. Am J Dermatopathol. 2019 Nov;41(11):794-798 Authors: Wilkinson PE, Gopalakrishnan R, Argyris PP Abstract Intraoral cutaneous hamartomas (ICHs) are uncommon mucosal lesions characterized microscopically by a combination of cutaneous structures, including various stages of follicular and sebaceous elements. Due to their rarity, the clinicopathologic...
Tue Mar 17, 2020 12:03
Related ArticlesFibrin glue-assisted excision of a large recurrent microphthalmic cyst. J AAPOS. 2019 02;23(1):49-51 Authors: Jones RK, Currie ZI, Salvi SM Abstract Microphthalmic cysts are rare. Although small cysts can be left in situ to promote orbital expansion, large cysts require drainage or surgical excision. Complete surgical excision is notoriously difficult, and incomplete excision may result in cyst reformation. We describe a novel method...
Tue Mar 17, 2020 12:03
Related ArticlesPrimary lacrimal sac diffuse large B-cell lymphoma in a child. J AAPOS. 2019 02;23(1):53-55 Authors: Parikh D, Rodgers R, Kodsi S Abstract We report the case of a 13-year-old boy who presented with a 2-month history of left eyelid swelling, ecchymosis, and epiphora. Magnetic resonance imaging revealed a lobulated lesion in the region of the left lacrimal sac extending to the left nasolacrimal duct. Biopsy revealed diffuse large B-cell...
Tue Mar 17, 2020 12:03
Related ArticlesPotential Diagnostic Pitfalls in Evaluating Immunohistochemistry for Cervical Myofibroblastomas. Int J Gynecol Pathol. 2019 Nov;38(6):597-601 Authors: Song S, Ziober A, Cooper K Abstract Cervicovaginal myofibroblastoma (CVM) is a rare benign mesenchymal tumor of the lower female genital tract that shows chromosomal loss of 13q14 (RB1 gene located in this region). The aim of this study was to investigate the utility of immunohistochemistry...
Tue Mar 17, 2020 12:03
Related ArticlesMultiple Luteinized Follicle Cysts of the Ovary in a Patient With a Pituitary Adenoma: Report of a Case and Review of the Literature. Int J Gynecol Pathol. 2019 Nov;38(6):562-567 Authors: Lebok P, Zuna RE, Holman LL, Young RH Abstract The case of a 36-yr-old woman with a pituitary adenoma who was found to have bilateral ovarian masses is reported. The right ovary was removed, measured 15 cm in maximum dimension, and contained multiple...
Tue Mar 17, 2020 12:03
Related ArticlesClassic and "Dissecting" Gonadoblastoma in a Phenotypic Girl With a 46, XX Peripheral Karyotype and No Evidence of a Disorder of Sex Development. Int J Gynecol Pathol. 2019 Nov;38(6):581-587 Authors: Roth LM, Davis MM, Czernobilsky B Abstract Herein, we report a case of a 9-yr-old girl who had a 46, XX peripheral karyotype and apparent developmentally normal ovaries. She presented with abdominal pain and a right adnexal mass. No clinical...
Tue Mar 17, 2020 12:03
Related ArticlesMoAIMS: efficient software for detection of enriched regions of MeRIP-Seq. BMC Bioinformatics. 2020 Mar 14;21(1):103 Authors: Zhang Y, Hamada M Abstract BACKGROUND: Methylated RNA immunoprecipitation sequencing (MeRIP-Seq) is a popular sequencing method for studying RNA modifications and, in particular, for N6-methyladenosine (m6A), the most abundant RNA methylation modification found in various species. The detection of enriched regions...
Tue Mar 17, 2020 12:02
Related ArticlesJoining Illumina paired-end reads for classifying phylogenetic marker sequences. BMC Bioinformatics. 2020 Mar 14;21(1):105 Authors: Liu T, Chen CY, Chen-Deng A, Chen YL, Wang JY, Hou YI, Lin MC Abstract BACKGROUND: Illumina sequencing of a marker gene is popular in metagenomic studies. However, Illumina paired-end (PE) reads sometimes cannot be merged into single reads for subsequent analysis. When mergeable PE reads are limited, one...
Tue Mar 17, 2020 12:02
Related ArticlesMachine learning prediction of oncology drug targets based on protein and network properties. BMC Bioinformatics. 2020 Mar 14;21(1):104 Authors: Dezső Z, Ceccarelli M Abstract BACKGROUND: The selection and prioritization of drug targets is a central problem in drug discovery. Computational approaches can leverage the growing number of large-scale human genomics and proteomics data to make in-silico target identification, reducing the...
Tue Mar 17, 2020 12:02
Related ArticlesDefining Major Surgery: A Delphi Consensus Among European Surgical Association (ESA) Members. World J Surg. 2020 Mar 14;: Authors: Martin D, Mantziari S, Demartines N, Hübner M, ESA Study Group Abstract BACKGROUND: Major surgery is a term frequently used but poorly defined. The aim of the present study was to reach a consensus in the definition of major surgery within a panel of expert surgeons from the European Surgical Association (ESA)....
Tue Mar 17, 2020 12:02
Staff in emergency departments often rely on heuristics and algorithms to make clinical decisions on a wide range of problems. Clinical predictor rules such as the Ottawa ankle rules serve to reduce the need for unnecessary radiographs and help to give frontline staff the confidence to make a diagnosis. The current study aimed to achieve consensus on the variables to test for inclusion in a set of predictor rules for suspected fractures of the mandible and midface. A three-stage modified Delphi study...
Tue Mar 17, 2020 02:00
Orthognathic surgery is an elective procedure that is done in healthy individuals so complications such as thromboembolic events are rare. Pharmacological thromboprophylaxis, which reduces the risk of these events, may also increase blood loss and potentially the risk of life-threatening haemorrhage, so a state of clinical equipoise exists about whether it should be given routinely. We systematically reviewed published papers to identify the incidence of venous thromboembolism and haemorrhage in...
Tue Mar 17, 2020 02:00
Assessment of the nose is critical in evaluating obstructive sleep apnea (OSA) because the nose plays an important role in the physiology of sleep by regulating nasal airway resistance and stimulating ventilation. Nasal obstruction is common in sleep apnea, contributes to OSA, and interferes with tolerance of OSA treatment with continuous positive airway pressure (CPAP) or oral appliances. Medical treatment of nasal obstruction and rhinitis with nasal corticosteroid sprays is associated with improved...
Tue Mar 17, 2020 02:00
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