One of the most common sites of extra‐thoracic distant metastasis of non‐small‐cell lung cancer is the brain. This study was performed to discover genes associated with postoperative brain metastasis in operable lung adenocarcinoma (LUAD). RNA seq was performed in specimens of primary LUAD from seven patients with brain metastases and 45 patients without recurrence. Immunohistochemical (IHC) assays of the differentially‐expressed genes were conducted in 272 surgical‐resected LUAD specimens. LASSO...
3h
Mechanisms underlying adiposity‐colorectal cancer (CRC) association are incompletely understood. Using UK Biobank data, we investigated the role of C‐reactive protein (CRP), hemoglobin‐A1c (HbA1c), and (jointly) sex hormone‐binding globulin (SHBG) and testosterone, in explaining this association. Total effect of obesity vs normal‐weight (based on waist circumference, body mass index, waist‐hip ratio) on CRC risk was decomposed into natural direct (NDE) and indirect (NIE) effects using sequential...
3h
Abstract Background Exercise-based strategies are used to prevent muscle injuries in football and studies on different competitive-level populations may provide different results. Objectives To evaluate the effectiveness of exercise-based muscle injury prevention strategies in adult elite football. ...
3h
As the author mentioned in this publication, the correction of infra-orbital groove by microfat injection did increase the postoperative satisfaction of lower blepharoplasty surgery1. In this study, we want to explore whether this procedure can replace the previous fat pad transposition. Months after the microfat injection, we have observed that fat continues to be present but its volume gradually disappears, and, with some, it totally vanishes. With fat pad transposition, the fat volume does not...
4h
Completion lymph node dissection (CLND) for malignant melanoma is performed for regional cancer control and is associated with a high complication rate. It is unknown whether post-operative complications influence cancer recurrence or survival. Our aim was to evaluate risk factors for short- and long-term complications after CLND, and to determine whether complications affect recurrence or survival.
4h
Consultant Plastic Surgeon and Chair of the Plastic, Reconstructive and Aesthetic Surgical Expert Advisory Group (PRASEAG) of the Medicines and Healthcare products Regulatory Agency (MHRA)
22h
In the UK the BAPRAS (British Association of Plastic, Reconstructive and Aesthetic Surgeons) meetings have always represented the ideal platform for disseminating new information in the field of plastic surgery. Previous studies have suggested the publication rate for these meetings has been falling. Our aim was to re-assess the conversion rates of presented abstracts to publications. All abstracts from BAPRAS meetings between Winter 2014 and Summer 2016 were included. PubMed and Google Scholar databases...
22h
Diver and Lewis described a modification of the “Jumping Man Flap”1. In fact, what they have described is a modification of the 5-flap Z-plasty. This was described by Hirschowitz et al.2 It is not a jumping man as it has no body.
22h
we find the paper published by Ziegler et al in 2018,1 regarding the anatomical relevance of the descending genicular articular artery (DGA), of great interest. Indeed, reports of the medial thigh as a flap donor site have increased in recent years . Supplied by the DGA, the free medial condyle (FMC) flap can provide vascularised bone and periosteum, and can be raised with a chimeric skin paddle.2 Lately, the superficial femoral artery (SFA) has been demonstrated as an innovative source of reliable...
22h
The generalization of skin grafting in clinical practice has improved the management of patients who experience trauma resulting in significant tissue loss. Skin grafting is currently considered the gold standard in the management of these cases.1 However, there are limits to this technique, particularly in cases of severe trauma. The amount of skin that can be harvested is limited, and a previously healthy body part is damaged in the process. In addition, grafting is a painful post-operative procedure,...
22h
Thumb carpometacarpal osteoarthritis (CMCJ OA) is a common problem. Joint denervation presents a number of theoretical advantages over more traditional surgical options; it is minimally invasive, it does not require a prosthesis or postoperative immobilisation, and does not preclude future surgery. It can be of particular benefit in patients who require good range of motion which other forms of surgery may compromise. Despite these potential advantages, selective denervation of the thumb CMCJ is...
22h
Soft tissue sarcomas (STS) of the extremities or trunk often require plastic reconstructive transfer of vital tissue for wound closure after resection. Literature on the oncologic outcome of patients receiving flap closure in comparison with patients receiving primary wound closure is very limited.
22h
: Attempting traditional cosmetic blepharoplasty in sunken eyelid may cause complications such as multiple folds, irregular or high placement of fold. Additional surgical procedures, such as orbital fat repositioning or free fat grafting, are introduced to correct the sunken appearance. The study sought to introduce a novel orbicularis oculi muscle flap (OOMF) rotation procedure for correction of the sunken eyelid during blepharoplasty.
22h
: In-transit metastases (ITMs) in melanoma are associated with poor prognosis, however a significant proportion of these patients survive for extended periods without further disease progression. We routinely use locoregional treatment e.g. Diphencyprone (DPCP) and/or isolated limb infusion (ILI) as long-term palliation. This study aimed to identify correct sequencing of these therapies based on disease burden and progression.
22h
Early diagnosis of wound infections are crucial as they have been shown to increase patient morbidity and mortality. We evaluated the use of Moleculight i:X to identify infections in acute open wounds in hand trauma. Data were collected from patients who attended the hand trauma unit over a 4 week period prior to having surgery. Wounds were inspected for clinical signs of infection and autofluorescence images were taken using the Moleculight i:X device. Wound swabs were taken and results interpreted...
22h
Capsular contracture remains a problem following breast implant surgery. Although impact of biofilm and implant surface on capsule formation have been demonstrated, interaction of microorganisms with different surface types has not been clarified yet. We aimed to compare the ability of biofilm formation of implants with different surfaces, under standard conditions and to demonstrate its impact on capsular contracture.
22h
Diabetes mellitus remains a significant public health problem, consuming over $400 billion every year. While Diabetes itself can be controlled effectively, impaired wound healing still occurs frequently in diabetic patients. Adipose-derived mesenchymal stem cells (ASC) provide an especially appealing source for diabetic wound cell therapy. With autologous approaches, functionality of ASCs largely underlie patient dependent factors. Diabetes is a significant diminishing factor of MSC functionality.
22h
Split thickness skin grafting (SSG) is an important modality for wound coverage, however it leads to donor site morbidity. Epidermal grafting (EG) is a promising option for autologous skin grafting which offers minimal donor site morbidity, though it is not known if EG is an effective clinical alternative for SSG. This study compared the efficacy of EG as an alternative to SSG in terms of wound healing outcomes, donor site morbidity, patient satisfaction and adverse events.
22h
To demonstrate a maneuver for achieving optimal force balance of reconstructed orbicularis oris during primary unilateral incomplete cleft lip reconstruction.
22h
Two smartphone applications that create 3D anatomical models using augmented...Read more on AuntMinnieEurope.comRelated Reading: 3D 'digital twin' adds personal touch to heart health U.K. group uses AR to simulate radiology procedures Spanish team visualizes 3D patient models on smartphones 3D cardiac model enhances heart valve surgery Augmented reality, AI algorithms bolster liver surgery
14h
The detailed forensic evidence presented in the 195-page police report on the...Read more on AuntMinnieEurope.comRelated Reading: Police report reveals mystery of vest in Swedish MRI case Prosecutor declines charges in Swedish MRI accident Prosecution looms for nurse in Swedish MRI accident Responsibility question surfaces in Swedish MRI accident MRI safety first? Or last?Comments: 3/17/2020 2:06:25 AMSVBO But, why on earth would anyone need/want to go to a hospital wearing a weighted...
1d
Radiology departments must actively prepare to deal with the COVID-19 crisis...Read more on AuntMinnieEurope.comRelated Reading: French group calls for more coronavirus protection U.K. group issues statement on imaging of COVID-19 Report: Radiology seminar linked to COVID-19 spread Imaging experts strive to get a grip on COVID-19 Chest CT beats DNA tests for early coronavirus diagnosis
1d
The aim of this study was to evaluate the long-term outcomes of Gillies and McLaughlin's dynamic muscle support with regard to functional outcomes and assess possible effects of comorbidities on both functional outcomes and reoperation and complication rates.A retrospective single-centre study was conducted of all patients (n=154) who underwent surgical correction of irreversible facial paralysis from 1994-2018. Patients with either Gillies procedure or McLaughlin's dynamic muscle support or a combination...
22h
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