Τετάρτη 18 Μαρτίου 2020


Ca2+/Calmodulin Binding to STIM1 Hydrophobic Residues Facilitates Slow Ca2+-Dependent Inactivation of the Orai1 Channel.
Related ArticlesCa2+/Calmodulin Binding to STIM1 Hydrophobic Residues Facilitates Slow Ca2+-Dependent Inactivation of the Orai1 Channel. Cell Physiol Biochem. 2020 Mar 17;54(2):252-270 Authors: Bhardwaj R, Augustynek BS, Ercan-Herbst E, Kandasamy P, Seedorf M, Peinelt C, Hediger MA Abstract BACKGROUND/AIMS: Store-operated Ca2+ entry (SOCE) through plasma membrane Ca2+ channel Orai1 is essential for many cellular processes. SOCE, activated by ER Ca2+...
pubmed: "cell physiol bioche...
Tue Mar 17, 2020 12:14
Over-expression of cyclo-oxygenase-2 predicts poor survival of patients with nasopharyngeal carcinoma: a meta-analysis.
Related ArticlesOver-expression of cyclo-oxygenase-2 predicts poor survival of patients with nasopharyngeal carcinoma: a meta-analysis. J Laryngol Otol. 2020 Mar 16;:1-6 Authors: Sim CC, Sim EU Abstract OBJECTIVES: The conclusive prognostic significance of cyclo-oxygenase-2 has been determined in various cancers but not in nasopharyngeal carcinoma. Therefore, this study aimed to evaluate the relationship of cyclo-oxygenase-2 expression with the survival...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Tue Mar 17, 2020 12:10
Efficacy of small-volume gastrografin videofluoroscopic screening for detecting pharyngeal leaks following total laryngectomy.
Related ArticlesEfficacy of small-volume gastrografin videofluoroscopic screening for detecting pharyngeal leaks following total laryngectomy. J Laryngol Otol. 2020 Mar 16;:1-4 Authors: Narayan M, Limbachiya S, Balasubramanian D, Subramaniam N, Thankappan K, Iyer S Abstract OBJECTIVES: Pharyngocutaneous fistulae are dreaded complications following total laryngectomy. This paper presents our experience using 3-5 ml gastrografin to detect pharyngeal leaks...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Tue Mar 17, 2020 12:10
Safety of tympanoplasty and ossiculoplasty performed by otorhinolaryngology trainees.
Related ArticlesSafety of tympanoplasty and ossiculoplasty performed by otorhinolaryngology trainees. J Laryngol Otol. 2020 Mar 16;:1-6 Authors: Alzhrani F, Aldueb R, Alosaimi K, Islam T, Almuhawas F, Alsanosi A Abstract OBJECTIVE: This study aimed to examine the impact of trainee involvement in performing tympanoplasty or tympano-ossiculoplasty on outcomes. METHODS: A retrospective analysis was performed of a prospective database of all patients...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Tue Mar 17, 2020 12:10
Post-rhinoplasty outcomes in an Indian population assessed using the FACE-Q appraisal scales: a prospective observational study.
Related ArticlesPost-rhinoplasty outcomes in an Indian population assessed using the FACE-Q appraisal scales: a prospective observational study. J Laryngol Otol. 2020 Mar 16;:1-5 Authors: Soni K, Patro SK, Aneja J, Kaushal D, Goyal A, Shakrawal N Abstract OBJECTIVES: The primary goal of rhinoplasty is patient satisfaction and improved quality of life. The present study was conducted to assess patient satisfaction with face and nose appearance, and quality...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Tue Mar 17, 2020 12:10
Low origin of the persistent hypoglossal artery associated with high carotid bifurcation: a case report.
Related ArticlesLow origin of the persistent hypoglossal artery associated with high carotid bifurcation: a case report. Surg Radiol Anat. 2020 Mar 14;: Authors: Suzuki S, Uchino A, Numaguchi Y Abstract PURPOSE: Persistent hypoglossal artery (PHA) is the second most common anastomosis between the carotid and vertebrobasilar systems and it demonstrates some variations. METHODS: Using magnetic resonance angiography, we diagnosed a case of...
radiol anat
Tue Mar 17, 2020 12:08
Investigating the relationships between social capital, chronic health conditions and health status among Australian adults: findings from an Australian national cohort survey.
Related ArticlesInvestigating the relationships between social capital, chronic health conditions and health status among Australian adults: findings from an Australian national cohort survey. BMC Public Health. 2020 Mar 14;20(1):329 Authors: Lee JK, Lin L, Magee C Abstract BACKGROUND: Social capital is a collective attribute of communities that determines health and well-being of populations. The collective resources in a high social capital community...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Factors associated with 36-month loss to follow-up and mortality outcomes among HIV-infected adults on antiretroviral therapy in Central Kenya.
Related ArticlesFactors associated with 36-month loss to follow-up and mortality outcomes among HIV-infected adults on antiretroviral therapy in Central Kenya. BMC Public Health. 2020 Mar 14;20(1):328 Authors: Wekesa P, McLigeyo A, Owuor K, Mwangi J, Nganga E, Masamaro K Abstract BACKGROUND: The scale-up of HIV treatment programs has resulted in a reduction in HIV-related morbidity and mortality. However, retention of patients in these programs remains...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Assertive outreach treatment versus care as usual for the treatment of high-need, high-cost alcohol related frequent attenders: study protocol for a randomised controlled trial.
Related ArticlesAssertive outreach treatment versus care as usual for the treatment of high-need, high-cost alcohol related frequent attenders: study protocol for a randomised controlled trial. BMC Public Health. 2020 Mar 14;20(1):332 Authors: Blackwood R, Wolstenholme A, Kimergård A, Fincham-Campbell S, Khadjesari Z, Coulton S, Byford S, Deluca P, Jennings S, Currell E, Dunne J, O'Toole J, Winnington J, Finch E, Drummond C Abstract BACKGROUND: Alcohol-related...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Assessment and prioritization of the WHO "best buys" and other recommended interventions for the prevention and control of non-communicable diseases in Iran.
Related ArticlesAssessment and prioritization of the WHO "best buys" and other recommended interventions for the prevention and control of non-communicable diseases in Iran. BMC Public Health. 2020 Mar 14;20(1):333 Authors: Bakhtiari A, Takian A, Majdzadeh R, Haghdoost AA Abstract BACKGROUND: The WHO's "best buys" and other recommended interventions are a menu of policy options and cost-effective interventions for the prevention and control of major...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Breastfeeding reduces ultra-processed foods and sweetened beverages consumption among children under two years old.
Related ArticlesBreastfeeding reduces ultra-processed foods and sweetened beverages consumption among children under two years old. BMC Public Health. 2020 Mar 14;20(1):330 Authors: Spaniol AM, da Costa THM, Bortolini GA, Gubert MB Abstract BACKGROUND: Breastfeeding and adequate complementary feeding are associated with healthy eating habits, prevention of nutritional deficiencies, obesity and non-communicable diseases. Our aim was to identify feeding...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Development and content validity of the Abilitator: a self-report questionnaire on work ability and functioning aimed at the population in a weak labour market position.
Related ArticlesDevelopment and content validity of the Abilitator: a self-report questionnaire on work ability and functioning aimed at the population in a weak labour market position. BMC Public Health. 2020 Mar 14;20(1):327 Authors: Wikström M, Anttila H, Savinainen M, Kouvonen A, Joensuu M Abstract BACKGROUND: The unemployed have lower work ability and poorer health than the employed. This situation deteriorates when unemployment continues. The long-term...
pubmed: "bmc public health"[...
Tue Mar 17, 2020 12:08
Destructive maxillary radiolucency in a 20-year-old female.
Related ArticlesDestructive maxillary radiolucency in a 20-year-old female. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Oct 13;: Authors: Lee KC, Peters SM, Pradhan JS, Alfi DM, Koslovsky DA, Philipone EM PMID: 32173397 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Epithelioid rhabdomyosarcoma: report of the first case in the jaw.
Related ArticlesEpithelioid rhabdomyosarcoma: report of the first case in the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 12;: Authors: de Aguiar MCF, de Noronha MS, Silveira RL, Araújo JAD, Werkema FS, Bell D, Caldeira PC Abstract OBJECTIVES: Epithelioid rhabdomyosarcoma (EpiRMS) is a novel morphologically distinct variant of rhabdomyosarcoma, with an unusually challenging microscopic diagnosis. The occurrence of rhabdomyosarcomas...
oral surg oral med
Tue Mar 17, 2020 12:07
Ligneous gingivitis secondary to plasminogen deficiency: a multidisciplinary diagnostic challenge.
Related ArticlesLigneous gingivitis secondary to plasminogen deficiency: a multidisciplinary diagnostic challenge. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 12;: Authors: MacPherson M, Pho M, Cox J, Armstrong J, Darling MR, McCord C Abstract Plasminogen deficiency is a genetic condition resulting in deposition of extravascular fibrin within mucosal tissues. Lesions associated with plasminogen deficiency most commonly affect the eyes, while...
oral surg oral med
Tue Mar 17, 2020 12:07
A submucosal nodule on the buccal mucosa.
Related ArticlesA submucosal nodule on the buccal mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Feb 14;: Authors: de Oliveira EM, Schuch LF, Caldeira PC, da Silva KD, Abdo EN, de Aguiar MCF PMID: 32173394 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Chemopreventive activity of Tualang honey against oral squamous cell carcinoma-in vivo.
Related ArticlesChemopreventive activity of Tualang honey against oral squamous cell carcinoma-in vivo. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 13;: Authors: Al-Koshab M, Alabsi AM, Bakri MM, Naicker MS, Seyedan A Abstract OBJECTIVE: The aim of this study was to evaluate the chemopreventive activity of Malaysian jungle Tualang honey (TH) after oral carcinogenesis induced with 4-nitroquinoline 1-oxide (4 NQO). STUDY DESIGN:...
oral surg oral med
Tue Mar 17, 2020 12:07
Edentulous left maxillary ridge ulcerative swelling.
Related ArticlesEdentulous left maxillary ridge ulcerative swelling. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Nov 28;: Authors: Tseng CH, Su CW, Chen CY, Wang WC, Chen YK PMID: 32173392 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Asymptomatic intrabony radiolucency of the anterior mandible.
Related ArticlesAsymptomatic intrabony radiolucency of the anterior mandible. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 May 16;: Authors: Sun HH, Lin SC, Park CM, Elo JA PMID: 32173391 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Assessment of TLR4 and TLR9 signaling and correlation with human papillomavirus status and histopathologic parameters in oral tongue squamous cell carcinoma.
Related ArticlesAssessment of TLR4 and TLR9 signaling and correlation with human papillomavirus status and histopathologic parameters in oral tongue squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 13;: Authors: Daskalopoulos AG, Avgoustidis D, Chaisuparat R, Karanikou M, Lazaris AC, Sklavounou A, Nikitakis NG Abstract OBJECTIVES: Toll-like receptors (TLRs) may promote or inhibit tumor progression. The aim of this study...
oral surg oral med
Tue Mar 17, 2020 12:07
Adherent white plaques in a nonsmoker.
Related ArticlesAdherent white plaques in a nonsmoker. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Apr 17;: Authors: Flores-Hidalgo A, Curran AE PMID: 32173389 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
A nodule in the temporomandibular joint area.
Related ArticlesA nodule in the temporomandibular joint area. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Mar 31;: Authors: Leite-Lima F, Fonseca FP, Gomez RS, Lehman LFC, de Castro WH, Campos FEB PMID: 32173388 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
A rapidly growing expansile lesion of the maxillary sinus in a child.
Related ArticlesA rapidly growing expansile lesion of the maxillary sinus in a child. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 12;: Authors: Bhula A, Husain M, Chandran R, Ferreira L PMID: 32173387 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
84-year-old woman with a right cheek mass.
Related Articles84-year-old woman with a right cheek mass. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Apr 12;: Authors: Canterbury CR, Walton DM, Shackelford AJ, Bergen MS, Peters SM PMID: 32173386 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Widely distributed purple-colored bullae and nodules in the oral cavity.
Related ArticlesWidely distributed purple-colored bullae and nodules in the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Mar 01;: Authors: Shi X, Lin D, Wang X, Wang H, Shi L, Wu F, Liu S, Yang L, Hou X, Wu L, Zhou H PMID: 32173385 [PubMed - as supplied by publisher]
oral surg oral med
Tue Mar 17, 2020 12:07
Treating fungus-induced allergic asthma: Do VDACs have the answer!
Related ArticlesTreating fungus-induced allergic asthma: Do VDACs have the answer! J Physiol. 2020 Mar 16;: Authors: Ahmad S, Ahmad A PMID: 32173869 [PubMed - as supplied by publisher]
pubmed: "j physiol"[jour]
Tue Mar 17, 2020 12:06
Evidence for associations between Th1/Th17 "hybrid" phenotype and altered lipometabolism in very severe Graves' orbitopathy.
Related ArticlesEvidence for associations between Th1/Th17 "hybrid" phenotype and altered lipometabolism in very severe Graves' orbitopathy. J Clin Endocrinol Metab. 2020 Mar 16;: Authors: Fang S, Zhang S, Huang Y, Wu Y, Lu Y, Zhong S, Liu X, Wang Y, Li Y, Sun J, Gu P, Zhou H, Fan X Abstract PURPOSE: To investigate the characteristics of Th1 and Th17 cell lineages for very severe Graves' orbitopathy (GO) development. METHODS: Flow cytometry...
American Goiter Association
Tue Mar 17, 2020 12:06
Dysphagia and Dysarthria in Children with Neuromuscular Diseases, a Prevalence Study.
Related ArticlesDysphagia and Dysarthria in Children with Neuromuscular Diseases, a Prevalence Study. J Neuromuscul Dis. 2020 Mar 11;: Authors: Kooi-van Es M, Erasmus CE, de Swart BJM, Voet NBM, van der Wees PJ, de Groot IJM, van den Engel-Hoek L, studygroup Dutch pediatric rehabilitation centers Abstract BACKGROUND: Dysphagia and dysarthria are frequently described in pediatric neuromuscular diseases (pNMD). The consequences can be substantial: failure...
Dysphagia - Rehabilitation
Tue Mar 17, 2020 12:04
Using experience-based co-design to improve the pre-treatment care pathway for people diagnosed with head and neck cancer.
Related ArticlesUsing experience-based co-design to improve the pre-treatment care pathway for people diagnosed with head and neck cancer. Support Care Cancer. 2020 Feb;28(2):739-745 Authors: Brady GC, Goodrich J, Roe JWG Abstract BACKGROUND: Recent studies have highlighted that people diagnosed with head and neck cancer (HNC) have complex information needs. They are subject to multiple clinical appointments with numerous healthcare professionals in...
Dysphagia - Rehabilitation
Tue Mar 17, 2020 12:04
Quantitative Assessment of Parental Somatic Mosaicism for Copy-Number Variant (CNV) Deletions.
Related ArticlesQuantitative Assessment of Parental Somatic Mosaicism for Copy-Number Variant (CNV) Deletions. Curr Protoc Hum Genet. 2020 Jun;106(1):e99 Authors: Liu Q, Grochowski CM, Bi W, Lupski JR, Stankiewicz P Abstract As genome sequencing methodologies have become more sensitive in detecting low-frequency rare-variant events, the link between post-zygotic mutagenesis and somatic mosaicism in the etiology of several human genetic conditions other...
Rare Cancers
Tue Mar 17, 2020 12:03
Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas.
Related ArticlesGene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas. J Gastrointest Oncol. 2020 Feb;11(1):45-54 Authors: Hoang T, Ganesan AK, Hiyama D, Dayyani F Abstract Background: Genetic analysis of gastrointestinal malignancies shows a great number of mutations. Most mutations found in gastric tumors are also found in colorectal and esophageal tumors. The challenge remains to identify mutations that distinguish gastric...
Rare Cancers
Tue Mar 17, 2020 12:03
Symptomatic oral squamous papilloma of the uvula - a rare incidental finding.
Related ArticlesSymptomatic oral squamous papilloma of the uvula - a rare incidental finding. Malays Fam Physician. 2019;14(3):74-76 Authors: Ramasamy K, Kanapaty Y, Abdul Gani N Abstract Oral squamous papillomas are benign neoplasms of the oral cavity that occur commonly on the palate. Albeit benign and often asymptomatic, they may still cause concern due to their appearance, which may mimic other malignant oral pathologies. Human papillomavirus (HPV)...
Rare Cancers
Tue Mar 17, 2020 12:03
Update on systemic therapy for advanced soft-tissue sarcoma.
Related ArticlesUpdate on systemic therapy for advanced soft-tissue sarcoma. Curr Oncol. 2020 Feb;27(Suppl 1):25-33 Authors: Smrke A, Wang Y, Simmons C Abstract Background: Soft-tissue sarcoma (sts) represents a rare group of mesenchymal neoplasms comprising more than 50 heterogeneous subtypes. Great efforts have been made to increase the understanding of the treatment of advanced sts (unresectable or metastatic disease). We set out to determine whether...
Rare Cancers
Tue Mar 17, 2020 12:03
Systemic therapy in pediatric-type soft-tissue sarcoma.
Related ArticlesSystemic therapy in pediatric-type soft-tissue sarcoma. Curr Oncol. 2020 Feb;27(Suppl 1):6-16 Authors: Ingley KM, Cohen-Gogo S, Gupta AA Abstract Soft-tissue sarcoma (sts) is rare and represents approximately 7% of cancers in children and in adolescents less than 20 years of age. Rhabdomyosarcoma (rms) is most prevalent in children less than 10 years of age and peaks again during adolescence (16-19 years of age). Multi-agent chemotherapy...
Rare Cancers
Tue Mar 17, 2020 12:03
Well-Differentiated Papillary Mesothelioma With Two Synchronous Serous Gynaecologic Carcinomas in a 62-Year-Old Woman: Lessons Learned for the Gynaecologic Surgeon.
Related ArticlesWell-Differentiated Papillary Mesothelioma With Two Synchronous Serous Gynaecologic Carcinomas in a 62-Year-Old Woman: Lessons Learned for the Gynaecologic Surgeon. J Obstet Gynaecol Can. 2020 Mar 12;: Authors: McGinnis JM, Bloomfield V, Kazerouni H, Helpman L Abstract BACKGROUND: Well-differentiated papillary mesothelioma (WDPM) is a rare tumor of unknown malignant potential. It is typically diagnosed incidentally during benign gynaecologic...
Rare Cancers
Tue Mar 17, 2020 12:03
The key role of oncopharmacology in therapeutic management, from common to rare cancers: A literature review.
Related ArticlesThe key role of oncopharmacology in therapeutic management, from common to rare cancers: A literature review. Therapie. 2020 Feb 13;: Authors: Louveau B, Jouenne F, Kaguelidou F, Landras A, Goldwirt L, Mourah S Abstract The therapeutic management of cancers has undergone considerable changes due to the emergence of genomics tools and tumor molecular deciphering. In this context, a dual pharmacological approach based on pharmacogenomic...
Rare Cancers
Tue Mar 17, 2020 12:03
Targeted α-Emitter Therapy of Neuroendocrine Tumors.
Related ArticlesTargeted α-Emitter Therapy of Neuroendocrine Tumors. Semin Nucl Med. 2020 Mar;50(2):171-176 Authors: Kunikowska J, Królicki L Abstract Neuroendocrine tumors (NET) are a heterogeneous group of neoplasms, arising from cells of the endocrine system, with various clinical behaviors. Although these neoplasms are considered rare, a significant increase in the incidence and detectability of NET has been noted in many epidemiological studies...
Rare Cancers
Tue Mar 17, 2020 12:03
Clinical Practice Guidelines for Bladder Cancer 2019 edition by the Japanese Urological Association: Revision working position paper.
Related ArticlesClinical Practice Guidelines for Bladder Cancer 2019 edition by the Japanese Urological Association: Revision working position paper. Int J Urol. 2020 Mar 14;: Authors: Matsumoto H, Shiraishi K, Azuma H, Inoue K, Uemura H, Eto M, Ohyama C, Ogawa O, Kikuchi E, Kitamura H, Shinohara N, Takahashi S, Tsuzuki T, Nakagawa M, Narumi Y, Nishiyama H, Habuchi T, Hinotsu S, Fujii Y, Fujimoto K, Fujimoto H, Mizowaki T, Matsuyama H Abstract The Clinical...
Rare Cancers
Tue Mar 17, 2020 12:03
Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature.
Related ArticlesBirt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature. BMC Med Genet. 2020 Mar 14;21(1):52 Authors: Balsamo F, Cardoso PAS, do Amaral Junior SA, Theodoro TR, de Sousa Gehrke F, da Silva Pinhal MA, Bianco B, Waisberg J Abstract BACKGROUND: Birt-Hogg-Dubé syndrome (BHDS) is a rare autosomal dominant genodermatosis characterized by benign growth of the hair...
Rare Cancers
Tue Mar 17, 2020 12:03

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