Summary This systematic review and network meta‐analysis synthesized evidence on the effects of third‐wave cognitive behaviour therapies (3wCBT) on body weight, and psychological and physical health outcomes in adults with overweight or obesity. Studies that included a 3wCBT for the purposes of weight management and measured weight or body mass index (BMI) pre‐intervention and ≥ 3 months post‐baseline were identified through database searches (MEDLINE, CINAHL, Embase, Cochrane database [CENTRAL],...
4m
Summary Despite rising mental health problems worldwide, engaging men to seek mental health support is challenging. Male‐only lifestyle interventions have shown promise for improving men's physical health, but the overall impact of these programs on psychological outcomes is unclear. This review aimed to evaluate the impact of male‐only lifestyle interventions on men's mental health and to identify if any study or intervention features were associated with effectiveness. A systematic literature...
16h
Abstract Background A clinical swallow examination (CSE) provides integral information that informs the diagnostic decision‐making process within dysphagia management. However, multiple studies have highlighted a high degree of reported variability within the CSE process. It has been hypothesized that such variability may be the result of the clinical reasoning process rather than poor practices. Aims To elucidate the nature of expert, speech–language therapists’ (SLTs) clinical...
8m
Abstract Background Behavioural and neuropsychological studies on elderly populations concentrate on many aspects of cognitive functioning, but significantly less research concerns communication processes, including aspects of verbal communication skills, pragmatic issues that are important for performing social tasks at every age. Aims To characterize the variability in changes that occur with age in the domain of pragmatic aspects of verbal communication skills in a group of individuals...
8m
Abstract A major challenge for electroencephalograph (EEG) studies on pediatric populations is that large amounts of data are lost due to artifacts (e.g., movement and blinks). Independent component analysis (ICA) can separate artifactual and neural activity, allowing researchers to remove such artifactual activity and retain a greater percentage of EEG data for analyses. However, manual identification of artifactual components is time‐consuming and requires subjective judgment. Automated algorithms,...
12m
Abstract There is increased interest in the development of cognitive training targeting working memory (WM) to alleviate anxiety symptoms, but the effectiveness of such an approach is unclear. Improved understanding of the effect of cognitive training on anxiety may facilitate the development of more effective cognitive training treatment for anxiety disorders. This study uses an experimental approach to examine the interplay of WM and anxiety following WM training. Previous studies show that increased...
14h
Cancers, Vol. 12, Pages 710: Cancer Genetics and Therapeutic Opportunities in Urologic Practice Cancers doi: 10.3390/cancers12030710 Authors: Jacob J. Adashek Alex Leonard Jason Roszik Arjun K. Menta Giannicola Genovese Vivek Subbiah Pavlos Msaouel This article aims to summarize the current literature on genetic alterations related to tumors of the genitourinary tract. Novel associations have recently been reported between specific DNA alterations and genitourinary...
19m
Cancers, Vol. 12, Pages 709: Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia Cancers doi: 10.3390/cancers12030709 Authors: Elise Aasebø Frode S. Berven Sushma Bartaula-Brevik Tomasz Stokowy Randi Hovland Marc Vaudel Stein Ove Døskeland Emmet McCormack Tanveer S. Batth Jesper V. Olsen Øystein Bruserud Frode Selheim Maria Hernandez-Valladares Acute myeloid leukemia (AML) is a hematological cancer...
17h
Cancers, Vol. 12, Pages 707: Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer Cancers doi: 10.3390/cancers12030707 Authors: Paul Kubelac Catherine Genestie Aurelie Auguste Soizick Mesnage Audrey Le Le Formal Patricia Pautier Sebastien Gouy Philippe Morice Enrica Bentivegna Amandine Maulard Julien Adam Patriciu Achimas-Cadariu Alexandra Leary Ovarian cancer (OC) is sensitive to upfront chemotherapy, which...
20h
Cancers, Vol. 12, Pages 708: The Microrna-143/145 Cluster in Tumors: A Matter of Where and When Cancers doi: 10.3390/cancers12030708 Authors: Valeria Poli Laura Seclì Lidia Avalle The establishment and spreading of cancer involve the acquirement of many biological functions including resistance to apoptosis, enhanced proliferation and the ability to invade the surrounding tissue, extravasate from the primary site, survive in circulating blood, and finally extravasate and...
20h
Cancers, Vol. 12, Pages 705: Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights Cancers doi: 10.3390/cancers12030705 Authors: Vanesa Gottifredi Lisa Wiesmüller In this Special Issue, we would like to focus on the various functions of the RAD52 helicase-like protein and the current implications of such findings for cancer treatment. Over the last few years, various laboratories have discovered particular activities of mammalian RAD52—both...
21h
Cancers, Vol. 12, Pages 706: You Have Got a Fast CAR: Chimeric Antigen Receptor NK Cells in Cancer Therapy Cancers doi: 10.3390/cancers12030706 Authors: Aline Pfefferle Nicholas D. Huntington The clinical success stories of chimeric antigen receptor (CAR)-T cell therapy against B-cell malignancies have contributed to immunotherapy being at the forefront of cancer therapy today. Their success has fueled interest in improving CAR constructs, identifying additional antigens to...
21h
Cancers, Vol. 12, Pages 704: MicroRNAs in Cancer Treatment-Induced Cardiotoxicity Cancers doi: 10.3390/cancers12030704 Authors: Laura Pellegrini Sara Sileno Marco D’Agostino Eleonora Foglio Maria Cristina Florio Vincenzo Guzzanti Matteo Antonio Russo Federica Limana Alessandra Magenta Cancer treatment has made significant progress in the cure of different types of tumors. Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside...
22h
The hope is that we will have a coronavirus vaccine in 12-18 months, but for that to happen we may have to rely on untested techniques - and that comes with its own risks.
20m
To really reduce the potential coronavirus death toll, modelling suggests that the UK needs to bring in stricter social distancing and perhaps close schools
13h
Doom Eternal does contain gratuitous violence, but the evidence suggests violence in video games doesn't affect people's behaviour in the real world, says Jacob Aron
17h
In response to the covid-19 pandemic, many governments are now recommending social distancing. Here's a guide to what it means for you
17h
In a cornfield in India, Urbasi Sinha ran an experiment that may challenge the rules of quantum mechanics and paves the way for higher dimensional quantum computing
18h
This image of an enormous ship under construction features in a new book and show that challenge common ideas about beauty - while the real ship may help cut carbon emissions
22h
Abstract Objectives To evaluate the management of alveolar cleft defects with proximal tibia bone grafts by late secondary alveolar bone grafting. Materials and Methods Fifteen patients were studied, nine males and six females within age range of 21–32 years. All the patients were treated with cancellous portion of the proximal tibial bone graft, harvested...
55m
Abstract Previous researches have confirmed that modified nanoscale carbon black (MCB) can decrease the bioavailability of heavy metals in soil and accumulation in plant tissues, resulting in the increase of biomass of plant. However, as a nanoparticle, the effects of MCB on plant cell morphology and microbial communities in Cd-contaminated soil are poorly understood. This study, through greenhouse experiments, investigated the effects of MCB as an amendment for 5 mg·kg-1 Cd-contaminated...
3h
Abstract Urbanization growth may alter the hydrologic conditions and processes driving carbon concentrations in aquatic systems through local changes in land use. Here, we explore dissolved carbon concentrations (DIC and DOC) along urbanization gradient in Santa Catarina Island to evaluate potential increase of CO2 in streams. Additionally, we assessed chemical, physical, and biotic variables to evaluate direct and indirect effects of urbanization in watersheds. We defined 3 specific...
5h
Abstract We investigated the hypothesis that root morphology plays a crucial role in the variation in chromium (Cr) accumulation among peanut (Arachis hypogaea L.) cultivars, using the relationship between Cr accumulation and morphological characteristics of six peanut cultivars determined under 0, 10, 25, 75, and 100 μmol L−1 Cr(VI) via hydroponic experiment. Significant variations were observed in Cr accumulation and root morphological parameters among peanut cultivars at the...
5h
Abstract Roxarsone (3-nitro-4-hydroxyphenylarsonic acid) is an extensively used organoarsenic feed additive. The effective removal of arsenic from roxarsone degradation before discharging is of great importance for controlling artificial arsenic pollution in aquatic environment. In this study, a bifunctional TiO2/ferrihydrite (TiO2/FeOOH) hybrid was synthesized by a hydrothermal method for the simultaneously photocatalytic degradation of roxarsone and adsorption removal of released...
6h
Abstract Excess sludge contains a high amount of protein, which can be recovered to prepare protein foaming agents and other products with high added value. Enzymatic hydrolysis (EH) is a promising technology for the recovery of protein from excess sludge, and ultrasound has been identified as a potential method to assist in sludge disintegration. Ultrasonic pretreatment was combined with alkaline protease hydrolysis to extract protein from excess sludge produced by A2/O treatment...
11h
Abstract Owing to their physical and chemical properties, particles generated by the abrasion of tyre tread against road surfaces, or tyre wear particles, are recognised as microplastics. Recent desk-based studies suggest tyre wear to be a major contributor of microplastic emissions to the environment. This study aimed to quantify tyre wear in roadside drains and the natural environment near to a major road intersection. Tyre particles were identified by visual identification and...
13h
Abstract This study was conducted to assess the concentrations of cadmium (Cd) and lead (Pb) in soils of tobacco field and plants were collected in the edge of Sichuan Basin, China (Panzihua, Guangyuan, Luzhou and Yibin). Ecological risk of Cd and Pb in soil and human health risk from tobacco leaves were also assessed. The maximum Cd and Pb concentrations in soil were obtained in Yibin (2.94 mg/kg) and Luzhou (54.2 mg/kg), respectively. Ecological risk of Cd and Pb in tobacco soils...
18h
Abstract Planktonic ciliate composition and distribution together with physicochemical variables were investigated in a shallow hypersaline lagoon, Pulicat, India, during three seasons, i.e., pre-monsoon (PRM), monsoon (MON), and post-monsoon (POM). The low freshwater inflow, evaporation, and closure of the lake mouth were the main factors for the hypersaline conditions in Pulicat Lake. The average depth and salinity were 1.8 ± 0.12 m (0.8 to 2.8 m) and 35.3 ± 1.68 (12.5 to 61),...
20h
Abstract Simultaneous removal of NOx and SO2 is carried out by an oxidation-absorption process, which NO oxidized by active hydroxyl radicals (·OH) derived from catalytic decomposition of vaporized H2O2 over Fe3O4/TiO2 and then adsorbed by NaOH solution along with SO2. Fe3O4/TiO2 synthesized by wet impregnation method with an additional reduction under H2 atmosphere was characterized by XRD, FTIR, BET, XPS, and VSM analysis. Effects of H2O2 concentration, H2O2 injection rate, reaction...
1d
Viruses, Vol. 12, Pages 327: Metagenomic Detection of Two Vientoviruses in a Human Sputum Sample Viruses doi: 10.3390/v12030327 Authors: Fernando Lázaro-Perona Elias Dahdouh Sergio Román-Soto Sonia Jiménez-Rodríguez Carlos Rodríguez-Antolín Fernando de la Calle Alexander Agrifoglio Francisco Javier Membrillo Julio García-Rodríguez Jesús Mingorance We used metagenomics to analyze one sputum sample from a patient with symptoms of a respiratory infection...
58m
Viruses, Vol. 12, Pages 326: Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors Viruses doi: 10.3390/v12030326 Authors: Danwei Yu Yang Su Xiaohui Ding Yuanmei Zhu Bo Qin Huihui Chong Sheng Cui Yuxian He Peptides derived from the C-terminal heptad repeat (CHR) region of HIV-1 gp41 is potent viral membrane fusion inhibitors, such as the first clinically approved peptide drug T20 and a group...
58m
Viruses, Vol. 12, Pages 324: The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take Viruses doi: 10.3390/v12030324 Authors: Sharma Hagbom Svensson Nordgren Innate resistance to viral infections can be attributed to mutations in genes involved in the immune response, or to the receptor/ligand. A remarkable example of the latter is the recently described Mendelian trait resistance to clinically important and globally predominating...
17h
Viruses, Vol. 12, Pages 325: Coxsackievirus B3 Infection of Human Neural Progenitor Cells Results in Distinct Expression Patterns of Innate Immune Genes Viruses doi: 10.3390/v12030325 Authors: Oh Gim Lee Park Shin Coxsackievirus B3 (CVB3), a member of Picornaviridae family, is an important human pathogen that causes a wide range of diseases, including myocarditis, pancreatitis, and meningitis. Although CVB3 has been well demonstrated to target murine neural...
17h
Viruses, Vol. 12, Pages 323: A Novel Hepe-Like Virus from Farmed Giant Freshwater Prawn Macrobrachium rosenbergii Viruses doi: 10.3390/v12030323 Authors: Xuan Dong Tao Hu Qingyuan Liu Chen Li Yani Sun Yiting Wang Weifeng Shi Qin Zhao Jie Huang The family Hepeviridae includes several positive-stranded RNA viruses, which infect a wide range of mammalian species, chicken, and trout. However, few hepatitis E viruses (HEVs) have been characterized from...
18h
Viruses, Vol. 12, Pages 322: Honey Bee Queens and Virus Infections Viruses doi: 10.3390/v12030322 Authors: Amiri Strand Tarpy Rueppell The honey bee queen is the central hub of a colony to produce eggs and release pheromones to maintain social cohesion. Among many environmental stresses, viruses are a major concern to compromise the queen’s health and reproductive vigor. Viruses have evolved numerous strategies to infect queens either via vertical transmission...
21h
Complex fluorescence decay of Thioflavin T, bound to amyloids, can be readily analyzed by phasor approach without modelling it. Thioflavin T self‐quenches, in presence of amyloid fibrils, as its molar concentration increases. Changes in ThT lifetime represents a serious warning when attempting quantification and comparison between samples in different conditions. Abstract The formation of amyloid structures has traditionally been related to human neurodegenerative pathologies and, in...
1h
Cross-sectional study of surgical quality with a novel evidence-based tool for low-resource settings
BackgroundAdverse events from surgical care are a major cause of death and disability, particularly in low-and-middle-income countries. Metrics for quality of surgical care developed in high-income settings are resource-intensive and inappropriate in most lower resource settings. The purpose of this study was to apply and assess the feasibility of a new tool to measure surgical quality in resource-constrained settings. MethodsThis is a cross-sectional study of surgical quality using a novel evidence-based...
1h
BackgroundPostnatal growth failure (PGF) in very low birthweight (VLBW) infants is a result of factors such as prematurity, acute illness and suboptimal nutritional support. Before this project began, 84% of appropriately grown VLBW infants in our neonatal intensive care unit experienced PGF. The aims of this quality improvement project were to reduce the percentage of infants discharged with PGF to less than 50% within 2 years and to maintain a rate of PGF under 50%. MethodsAll inborn VLBW infants...
1h
BackgroundMany care home residents cannot self-report their own health status. Previous studies have shown differences between staff and resident ratings. In 2012, we collected 10 168 pairs of health status ratings using the howRu health status measure. This paper examines differences between staff and resident ratings. MethodHowRu is a short generic person-reported outcome measure with four items: pain or discomfort (discomfort), feeling low or worried (distress), limited in what you can do (disability)...
1h
IJMS, Vol. 21, Pages 2068: Pic-Producing Escherichia coli Induces High Production of Proinflammatory Mediators by the Host Leading to Death by Sepsis International Journal of Molecular Sciences doi: 10.3390/ijms21062068 Authors: Itaynara L. Dutra Lorena G. Araújo Raissa G. Assunção Yago A. Lima Johnny R. Nascimento André A. M. Vale Patrícia C. S. Alves Liana O. Trovão Ana Carolina M. Santos Rosa M. Silva Lucilene A. Silva Márcia C. G. Maciel ...
1h
IJMS, Vol. 21, Pages 2070: Hyaluronic Acid Reduces Bacterial Fouling and Promotes Fibroblasts’ Adhesion onto Chitosan 2D-Wound Dressings International Journal of Molecular Sciences doi: 10.3390/ijms21062070 Authors: Ilaria Silvestro Mariangela Lopreiato Anna Scotto d’Abusco Valerio Di Lisio Andrea Martinelli Antonella Piozzi Iolanda Francolini Wound healing is a dynamic process that can be seriously delayed by many factors including infectious complications....
2h
IJMS, Vol. 21, Pages 2069: IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells International Journal of Molecular Sciences doi: 10.3390/ijms21062069 Authors: Yosuke Kamiya Takeshi Kikuchi Hisashi Goto Iichiro Okabe Yuhei Takayanagi Yuki Suzuki Noritaka Sawada Teppei Okabe Yuki Suzuki Shun Kondo Jun-ichiro Hayashi Akio Mitani Interleukin (IL)-35 is an immunosuppressive cytokine mainly produced by regulatory...
2h
IJMS, Vol. 21, Pages 2067: Comparative Transcriptome Analysis Provides Insights into the Seed Germination in Cotton in Response to Chilling Stress International Journal of Molecular Sciences doi: 10.3390/ijms21062067 Authors: Qian Shen Siping Zhang Shaodong Liu Jing Chen Huijuan Ma Ziqian Cui Xiaomeng Zhang Changwei Ge Ruihua Liu Yang Li Xinhua Zhao Guozheng Yang Meizhen Song Chaoyou Pang Gossypium hirsutum L., is a widely cultivated...
3h
IJMS, Vol. 21, Pages 2066: Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells
IJMS, Vol. 21, Pages 2066: Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21062066 Authors: Bhattarai Korhonen Toppila Koskela Kaarniranta Mysore Kauppinen Retinal pigment epithelial (RPE) cells maintain homeostasis at the retina and they are under continuous oxidative stress. Cigarette smoke is a prominent environmental risk factor for age-related macular degeneration...
15h
IJMS, Vol. 21, Pages 2063: Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation International Journal of Molecular Sciences doi: 10.3390/ijms21062063 Authors: Amirkavei Pitkänen Kaikkonen Kaarniranta André Koskelainen The induction of heat shock response in the macula has been proposed as a useful therapeutic strategy for retinal neurodegenerative diseases by promoting proteostasis and enhancing protective...
15h
IJMS, Vol. 21, Pages 2064: Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts International Journal of Molecular Sciences doi: 10.3390/ijms21062064 Authors: Huang Sudhadevi Fu Punathil-Kannan Ebenezer Ramchandran Putherickal Cheresh Zhou Ha Harijith Kamp Natarajan The sphingosine kinase 1 (SPHK1)/sphingosine–1–phosphate...
15h
IJMS, Vol. 21, Pages 2062: Candidate Genes for Freezing and Drought Tolerance Selected on the Basis of Proteome Analysis in Doubled Haploid Lines of Barley International Journal of Molecular Sciences doi: 10.3390/ijms21062062 Authors: Wójcik-Jagła Rapacz Dubas Krzewska Kopeć Nowicka Ostrowska Malaga Żur Plant tolerance to environmental stress is determined by a very complicated network composed of many intra- and extracellular factors. The...
15h
IJMS, Vol. 21, Pages 2065: The beta Subunit of Nascent Polypeptide Associated Complex Plays A Role in Flowers and Siliques Development of Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21062065 Authors: Jan Fíla Božena Klodová David Potěšil Miloslav Juříček Petr Šesták Zbyněk Zdráhal David Honys The nascent polypeptide-associated (NAC) complex was described in yeast as a heterodimer composed of two subunits, α and β, and...
15h
IJMS, Vol. 21, Pages 2060: Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21062060 Authors: Tsai Huang Wei Liu Lin Yi Lin Wang Chu Hsiao Hu Tai Chibby is an antagonist of β-catenin and is considered a potential tumor suppressor protein, but the role of Chibby in hepatocellular carcinoma (HCC) has not been...
16h
IJMS, Vol. 21, Pages 2059: Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer’s Disease Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21062059 Authors: Monika Schmidt Ondrej Benek Lucie Vinklarova Martina Hrabinova Lucie Zemanova Matej Chribek Vendula Kralova Lukas Hroch Rafael Dolezal Antonin Lycka Lukas Prchal Daniel Jun Laura Aitken Frank Gunn-Moore...
16h
IJMS, Vol. 21, Pages 2061: PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice International Journal of Molecular Sciences doi: 10.3390/ijms21062061 Authors: Wang Nakajima Gonzalez Tanaka Peroxisome proliferator-activated receptor (PPAR) α, β/δ, and γ modulate lipid homeostasis. PPARα regulates lipid metabolism in the liver, the organ that largely controls whole-body nutrient/energy...
16h
IJMS, Vol. 21, Pages 2058: Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights International Journal of Molecular Sciences doi: 10.3390/ijms21062058 Authors: Charlotte Rieux Stéphane Goffinont Franck Coste Zahira Tber Julien Cros Vincent Roy Martine Guérin Virginie Gaudon Stéphane Bourg Artur Biela Vincent Aucagne Luigi Agrofoglio Norbert Garnier Bertrand Castaing DNA glycosylases...
17h
IJMS, Vol. 21, Pages 2057: Identification of Telocytes in the Pancreas of Turtles—A role in Cellular Communication International Journal of Molecular Sciences doi: 10.3390/ijms21062057 Authors: Noor Samad Gandahi Botao Ding Yonghong Shi Xuebing Bai Jameel Ahmed Gandahi Waseem Ali Vistro Qiusheng Chen Ping Yang The existence of telocytes (TCs) has not yet been established in the pancreases of aquatic reptiles. Here, we report TCs in the exocrine pancreas...
17h
IJMS, Vol. 21, Pages 2056: Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity International Journal of Molecular Sciences doi: 10.3390/ijms21062056 Authors: Abdelkrim Khadir Sina Kavalakatt Dhanya Madhu Preethi Cherian Fahd Al-Mulla Jehad Abubaker Ali Tiss Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic...
18h
IJMS, Vol. 21, Pages 2055: Mechanosensitive Aspects of Cell Biology in Manual Scar Therapy for Deep Dermal Defects International Journal of Molecular Sciences doi: 10.3390/ijms21062055 Authors: Thomas Koller Deep dermal defects can result from burns, necrotizing fasciitis and severe soft tissue trauma. Physiological scar restriction during wound healing becomes increasingly relevant in proportion to the affected area. This massively restricts the general mobility of patients. External...
19h
IJMS, Vol. 21, Pages 2054: A Retrospective on eIF2A—and Not the Alpha Subunit of eIF2 International Journal of Molecular Sciences doi: 10.3390/ijms21062054 Authors: Anton A. Komar William C. Merrick Initiation of protein synthesis in eukaryotes is a complex process requiring more than 12 different initiation factors, comprising over 30 polypeptide chains. The functions of many of these factors have been established in great detail; however, the precise role of some of them and...
19h
IJMS, Vol. 21, Pages 2050: Transcriptomic and Network Analysis Identifies Shared and Unique Pathways across Dementia Spectrum Disorders International Journal of Molecular Sciences doi: 10.3390/ijms21062050 Authors: Jose A. Santiago Virginie Bottero Judith A. Potashkin Background: Dementia is a growing public health concern with an estimated prevalence of 50 million people worldwide. Alzheimer’s disease (AD) and vascular and frontotemporal dementias (VaD, FTD),...
20h
IJMS, Vol. 21, Pages 2053: Mechanistic Chromatographic Column Characterization for the Analysis of Flavonoids Using Quantitative Structure-Retention Relationships Based on Density Functional Theory International Journal of Molecular Sciences doi: 10.3390/ijms21062053 Authors: Buszewski Žuvela Sagandykova Walczak-Skierska Pomastowski David Wong This work aimed to unravel the retention mechanisms of 30 structurally different flavonoids separated on three...
20h
IJMS, Vol. 21, Pages 2052: Structure and Bioactive Properties of Novel Textile Dyes Synthesised by Fungal Laccase International Journal of Molecular Sciences doi: 10.3390/ijms21062052 Authors: Polak Wlizło Pogni Petricci Grąz Szałapata Osińska-Jaroszuk Kapral-Piotrowska Pawlikowska-Pawlęga Jarosz-Wilkołazka Novel sustainable processes involving oxidative enzymatic catalysts are considered as an alternative for classical organic chemistry....
20h
IJMS, Vol. 21, Pages 2048: Indole-3-Carbinol Derivative DIM Mitigates Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Inflammatory Response, Apoptosis and Regulating Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms21062048 Authors: Suvesh Munakarmi Lokendra Chand Hyun Beak Shin Kyu Yun Jang Yeon Jun Jeong 3,3′-Diindolylmethane (DIM), a metabolic product of indole-3-carbinol extracted from cruciferous vegetables...
21h
IJMS, Vol. 21, Pages 2047: Effect of Streptozotocin-Inducted Diabetes on the Pathophysiology of Enteric Neurons in the Small Intestine Based on the Porcine Diabetes Model International Journal of Molecular Sciences doi: 10.3390/ijms21062047 Authors: Michał Bulc Jarosław Całka Katarzyna Palus Hyperglycemia is one of the main causes of diabetes complications. Gastrointestinal (GI) disturbances are one of the most frequent complications during diabetes. The porcine digestive...
21h
IJMS, Vol. 21, Pages 2049: Cryptides Identified in Human Apolipoprotein B as New Weapons to Fight Antibiotic Resistance in Cystic Fibrosis Disease International Journal of Molecular Sciences doi: 10.3390/ijms21062049 Authors: Rosa Gaglione Angela Cesaro Eliana Dell’Olmo Rocco Di Girolamo Luca Tartaglione Elio Pizzo Angela Arciello Chronic respiratory infections are the main cause of morbidity and mortality in cystic fibrosis (CF) patients, and are characterized...
21h
IJMS, Vol. 21, Pages 2046: Generation of a Model to Predict Differentiation and Migration of Lymphocyte Subsets under Homeostatic and CNS Autoinflammatory Conditions International Journal of Molecular Sciences doi: 10.3390/ijms21062046 Authors: Catharina C. Gross Marc Pawlitzki Andreas Schulte-Mecklenbeck Leoni Rolfes Tobias Ruck Petra Hundehege Heinz Wiendl Michael Herty Sven G. Meuth The central nervous system (CNS) is an immune-privileged compartment...
21h
IJMS, Vol. 21, Pages 2051: On-treatment Serum Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) Level and Risk of Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B during Nucleot(s)ide Analogue Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21062051 Authors: Ayato Murata Nozomi Amano Sho Sato Hironori Tsuzura Ko Tomishima Shunsuke Sato Kohei Matsumoto Yuji Shimada Katsuyori Iijima Takuya Genda We...
21h
IJMS, Vol. 21, Pages 2043: Genome-Wide Association Mapping for Heat Stress Responsive Traits in Field Pea International Journal of Molecular Sciences doi: 10.3390/ijms21062043 Authors: Tafesse Gali Lachagari Bueckert Warkentin Environmental stress hampers pea productivity. To understand the genetic basis of heat resistance, a genome-wide association study (GWAS) was conducted on six stress responsive traits of physiological and agronomic importance in pea, with...
21h
IJMS, Vol. 21, Pages 2045: Abberant Immunoglobulin G Glycosylation in Rheumatoid Arthritis by LTQ-ESI-MS International Journal of Molecular Sciences doi: 10.3390/ijms21062045 Authors: Zhipeng Su Qing Xie Yanping Wang Yunsen Li Aberrant glycosylation has been observed in many autoimmune diseases. For example, aberrant glycosylation of immunoglobulin G (IgG) has been implicated in rheumatoid arthritis (RA) pathogenesis. The aim of this study is to investigate IgG glycosylation...
21h
IJMS, Vol. 21, Pages 2044: Effects of Long-Chain Fatty Acyl-CoA Synthetase 1 on Diglyceride Synthesis and Arachidonic Acid Metabolism in Sheep Adipocytes International Journal of Molecular Sciences doi: 10.3390/ijms21062044 Authors: Yang Cao Sutian Wang Shunqi Liu Yanli Wang Haiguo Jin Huihai Ma Xiaotong Luo Yang Cao Zhengxing Lian Long-chain fatty acyl-CoA synthetase (ACSLs) is an essential enzyme for the synthesis of fatty acyl-CoA. ACSL1 plays...
22h
IJMS, Vol. 21, Pages 2042: Abscisic Acid and Jasmonate Metabolisms Are Jointly Regulated During Senescence in Roots and Leaves of Populus trichocarpa International Journal of Molecular Sciences doi: 10.3390/ijms21062042 Authors: Natalia Wojciechowska Emilia Wilmowicz Katarzyna Marzec-Schmidt Agnieszka Ludwików Agnieszka Bagniewska-Zadworna Plant senescence is a highly regulated process that allows nutrients to be mobilized from dying tissues to other organs. Despite...
22h
IJMS, Vol. 21, Pages 2041: UbcH10 a Major Actor in Cancerogenesis and a Potential Tool for Diagnosis and Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21062041 Authors: Ivan Presta Fabiana Novellino Annalidia Donato Domenico La Torre Caterina Palleria Emilio Russo Natalia Malara Giuseppe Donato Malignant transformation is a multistep process in which several molecular entities become dysregulated and result in dysfunction in the...
1d
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου