Τετάρτη, 18 Μαρτίου 2020


Gating mechanism of hyperpolarization-activated HCN pacemaker channels
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
<i>Grasp55</i><sup>−/−</sup> mice display impaired fat absorption and resistance to high-fat diet-induced obesity
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Polar coupling enabled nonlinear optical filtering at MoS<sub>2</sub>/ferroelectric heterointerfaces
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Polaritonic molecular clock for all-optical ultrafast imaging of wavepacket dynamics without probe pulses
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
Single-photon quantum regime of artificial radiation pressure on a surface acoustic wave resonator
Nature Communications - current - nature.com science feeds
Tue Mar 17, 2020 02:00
GARS‐related disease in infantile spinal muscular atrophy: Implications for diagnosis and treatment
Abstract The majority of patients with spinal muscular atrophy (SMA) identified to date harbor a biallelic exonic deletion of SMN1. However, there have been reports of SMA‐like disorders that are independent of SMN1, including those due to pathogenic variants in the glycyl‐tRNA synthetase gene (GARS1). We report three unrelated patients with de novo variants in GARS1 that are associated with infantile‐onset SMA (iSMA). Patients were ascertained during inpatient hospital evaluations for complications...
American Journal of Medical Genetics Part A
Tue Mar 17, 2020 19:45
The clinical overlap between cardiac‐urogenital syndrome, Meacham syndrome, and PAGOD syndrome. Report of a new patient with cardiac‐urogenital syndrome
American Journal of Medical Genetics Part A
Tue Mar 17, 2020 19:45
Phenotypic expansion of OTUD6B‐related syndrome
American Journal of Medical Genetics Part A
Tue Mar 17, 2020 19:45
Better cognitive efficiency is associated with increased experimental anxiety
Abstract There is increased interest in the development of cognitive training targeting working memory (WM) to alleviate anxiety symptoms, but the effectiveness of such an approach is unclear. Improved understanding of the effect of cognitive training on anxiety may facilitate the development of more effective cognitive training treatment for anxiety disorders. This study uses an experimental approach to examine the interplay of WM and anxiety following WM training. Previous studies show that increased...
Psychophysiology
Tue Mar 17, 2020 19:28
Development of amoxicillin resistance in Escherichia coli after exposure to remnants of a non-related phagemid-containing E. coli: an exploratory study
To determine the effect of exposure to remnants of a phagemid-containing E. coli, killed by treatment with a propanol-based hand rub, on antimicrobial resistance in E. coli isolates.
Antimicrobial Resistance and Infection Control - Latest Articles
Mon Mar 16, 2020 02:00
Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis
Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic, epigenetic, and environmental factors affecting the articular joints contributing to cartilage and bone damage. Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS),...
Mediators of Inflammation
Tue Mar 17, 2020 10:20
Efficacy and safety of intensity-modulated radiotherapy alone versus intensity-modulated radiotherapy plus chemotherapy for treatment of intermediate-risk nasopharyngeal carcinoma
This study directs to evaluate the efficacy and safety of intensity-modulated radiotherapy (IMRT) alone versus IMRT plus chemotherapy in intermediate-risk NPC (stage II and T3N0M0).
Radiation Oncology - Latest Articles
Mon Mar 16, 2020 02:00
Physical exercise during acute exacerbations of chronic obstructive pulmonary disease: Australian physiotherapy practice
Chronic Respiratory Disease, Volume 17, Issue , January-December 2020. Evidence supports an important role for pulmonary rehabilitation (PR) after acute exacerbations of chronic obstructive pulmonary disease (AECOPD); however, the role of physical exercise during hospitalisation is less clear. This study evaluated Australian physiotherapy practice and clinical perspectives regarding exercise and physical activity for patients with AECOPD. A national survey of 123 Australian public hospitals was conducted...
SAGE Publications Ltd STM: Chronic Respiratory Disease: Table of Contents
Tue Mar 17, 2020 03:19
A Case of an Incidentally Removed Lingual Osseous Choristoma
Lingual osseous choristoma is a rare benign tumor consisting of normal matured bone tissue. It was first reported in 1913, and less than 100 cases of lingual osseous choristomas, mainly in their twenties and thirties, have been reported in the English literature until now. Here, we report an additional case of lingual osseous choristoma, in an elderly patient, that was incidentally removed by coughing and cured without additional interventions. An 89-year-old male patient was referred to our department...
Case Reports in Otolaryngology
Tue Mar 17, 2020 06:50
Occupational lifting and adverse pregnancy outcome: a systematic review and meta-analysis
This systematic review was conducted to help clarify the effect of lifting at work on pregnancy outcome, by focusing on specific exposure categories. A search in Medline and Embase identified 51 articles reporting association of spontaneous abortion (SA), preterm delivery (PTD) or small-for-gestational-age (SGA) infant with exposure to occupational lifting. A global validity score was assigned to each study and six potential sources of bias were considered in sensitivity analyses. For each exposure–outcome...
OEM Online First
Tue Mar 17, 2020 18:00
Annals of Neurology: Volume 87, Number 4, April 2020
A fluorescence photomicrograph of skeletal muscle from a zebrafish larva in which the slow skeletal muscle troponin T protein was knocked down resulting in a myopathic phenotype characterized by reduced muscle mass and curvature of the body. A novel mutation in the slow skeletal muscle troponin T (TNNT1) gene causes a type of congenital core‐rod myopathy in humans. Actin is immunostained green and nuclei are stained blue. The muscle fibers in the affected fish model are disrupted and irregular in...
Annals of Neurology
Tue Mar 17, 2020 18:42
Issue Information
Annals of Neurology
Tue Mar 17, 2020 18:42
Self‐Perceived Hearing Status Creates an Unrealized Barrier to Hearing Healthcare Utilization
Objective To examine sociodemographic and audiometric factors associated with hearing aid (HA) uptake in adults with hearing loss (HL), and to investigate the role of self‐perceived hearing status on pursuit of hearing treatment. The relationship between self‐perceived hearing status and HA adoption has not been reported in a nationally representative sample of United States (US) adults. Study Design Cross‐sectional analysis of nationwide household health survey. Methods Audiometric...
The Laryngoscope
Tue Mar 17, 2020 18:32
A Comparison of the Bacterial Nasal Microbiome in Allergic Rhinitis Patients and After Immunotherapy
Objectives/Hypothesis Recent research has examined the nasal microbiome in rhinosinusitis and nondiseased states. Given immunologic alterations in allergic rhinitis (AR) and after allergen immunotherapy (IT), we evaluated the nasal microbiome in these conditions. Study Design Cross‐sectional comparison. Methods In this cross‐sectional study, nasal swabs for microbiome analysis were collected from three patient groups: IT‐naïve AR patients, AR patients undergoing IT for greater...
The Laryngoscope
Tue Mar 17, 2020 18:32
Hospitalized Patients With New‐Onset Vocal Fold Immobility Warrant Inpatient Injection Laryngoplasty
Objectives To evaluate the impact of early inpatient bedside injection laryngoplasty (IL) in hospitalized patients with iatrogenic unilateral vocal fold immobility (UVFI). Study Design Retrospective cohort study. Methods A retrospective review of hospitalized patients with iatrogenic UVFI undergoing IL between September 2013 and June 2017 was performed. Patients had a swallow evaluation by a speech‐language pathologist and bedside IL. Evaluated outcomes included swallow scores,...
The Laryngoscope
Tue Mar 17, 2020 18:32
A Novel Laryngoscope With an Adjustable Distal Tip
Objectives Various laryngoscopes are currently available for supraglottic, glottic, and cervical esophageal exposure, yet none allow for adjustable articulation of the laryngoscope distal tip. We sought to create a new laryngoscope to improve anatomic field of view exposure. Study Design Novel laryngoscope device validation study. Materials and Methods Three‐dimensional printed plastic and titanium prototype designs were created using Solidworks. Validation testing was performed...
The Laryngoscope
Tue Mar 17, 2020 18:32
Neuromonitored Thyroid Surgery: Optimal Stimulation Based on Intraoperative EMG Response Features
Objectives To evaluate/compare normative electrophysiologic electromyography (EMG) response characteristics of recurrent laryngeal, vagus, and external branch of superior laryngeal nerve evoked with different stimulators used in neuromonitored thyroid surgery. Study Design Prospective crossover study Methods EMG responses obtained via endotracheal tube surface electrodes in 11 patients undergoing thyroid surgery were recorded when stimulated with four stimulators: two monopolar...
The Laryngoscope
Tue Mar 17, 2020 18:32
Atypical extended immune-related neutropenia in patient treated with pembrolizumab
Publication date: Available online 17 March 2020Source: European Journal of CancerAuthor(s): Pierre-Antoine Laurain, Térence Landrin, Sami Souidi, Philippe Beuzeboc, Florian Scotté
European Journal of Cancer
Tue Mar 17, 2020 18:30
Is there a difference in volumetric change and effectiveness comparing pedicled buccal-fat pad and abdominal fat when used as interpositional arthroplasty in the treatment of temporomandibular joint ankylosis?
Publication date: Available online 16 March 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Ajoy Roychoudhury, Surendra Acharya, Ongkila Bhutia, Ashu Seith Bhalla, Smita Manchanda, Ravindra Mohan Pandey
Oral and Maxillofacial Surgery
Tue Mar 17, 2020 18:11
Does Fee-For-Service Medicare Reimbursement Incentivize Volume over Value Among Oral and Maxillofacial Surgeons?
Publication date: Available online 16 March 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Nisarg A. Patel, Salim Afshar
Oral and Maxillofacial Surgery
Tue Mar 17, 2020 18:11
Is it necessary to free the inferior alveolar nerve from the proximal segment in the sagittal split osteotomy?
Publication date: Available online 16 March 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Srinivas Susarla, Russell Ettinger, Thomas B. Dodson
Oral and Maxillofacial Surgery
Tue Mar 17, 2020 18:11
Modulation of Post-Traumatic Immune Response Using the IL-1 Receptor Antagonist Anakinra for Improved Visual Outcomes
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Mon Mar 16, 2020 09:00
Enhancing A82846B production by artificial attB-assisted overexpression of orf10–orf11 genes in Kibdelosporangium aridum SIPI-3927
A82846B, producing by Kibdelosporangium aridum, is an important precursor of the semi-synthetic glycopeptide antibiotic Oritavancin. K. aridum produces three components A82846A, B and C, so it is essential to inc...
Applied and Industrial Microbiology
Mon Mar 16, 2020 02:00
Minimally invasive resection of symptomatic cervical rib for treatment of thoracic outlet syndrome
Publication date: Available online 16 March 2020Source: World NeurosurgeryAuthor(s): Charlotte Hawks, Sarah Herrera-Nicol, Mark E. Pruzansky, Arthur L. Jenkins
World Neurosurgery
Tue Mar 17, 2020 17:56
Auditory And Language Skills In Children With Auditory Brainstem Implants
Publication date: Available online 16 March 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Nayara Freitas Fernandes, Marcos de Queiroz Teles Gomes, Robinson Koji Tsuji, Ricardo Ferreira Bento, Maria Valéria Schimdt Goffi-Gomez
Pediatric Otorhinolaryngology
Tue Mar 17, 2020 17:51
A pulmonary ILC3 niche promotes neonatal mucosal immunity to respiratory bacterial infection and is associated with postnatal lung development
Mucosal Immunology, Published online: 17 March 2020; doi:10.1038/s41385-020-0283-9A pulmonary ILC3 niche promotes neonatal mucosal immunity to respiratory bacterial infection and is associated with postnatal lung development
Mucosal Immunology - Issue - nature.com science feeds
Tue Mar 17, 2020 02:00
A pulmonary ILC3 niche promotes neonatal mucosal immunity to respiratory bacterial infection and is associated with postnatal lung development
Mucosal Immunology - Issue - nature.com science feeds
Tue Mar 17, 2020 02:00
Persons in remission from recurrent low back pain alter trunk coupling under dual-task interference during a dynamic balance task
Abstract This study investigated effects of cognitive dual-task interference and task prioritization instructions on task performance and trunk control during a dynamic balance task in persons with and without recurrent low back pain (rLBP). First, we tested the hypothesis that those with rLBP rely more on cognitive resources than back-healthy controls, and therefore trunk kinematics would be altered under dual-task interference conditions. Then, we tested participants’ ability...
Experimental Brain Research
Tue Mar 17, 2020 02:00
I-waves in motor cortex revisited
Abstract I-waves represent high-frequency (~ 600 Hz) repetitive discharge of corticospinal fibers elicited by single-pulse stimulation of motor cortex. First detected and examined in animal preparations, this multiple discharge can also be recorded in humans from the corticospinal tract with epidural spinal electrodes. The exact underpinning neurophysiology of I-waves is still unclear, but there is converging evidence that they originate at the cortical level through synaptic input...
Experimental Brain Research
Tue Mar 17, 2020 02:00

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