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ABSTRACT Objective Mutations in the genes coding for succinate dehydrogenase (SDHx) are the most frequent germline alterations in pheochromocytomas and paragangliomas. Evidence for the advantages associated with pre‐symptomatic screening for SDHx mutation carriers is scarce. This study describes a nationwide cohort of these mutation carriers and aims to compare patients with clinical manifestations of the disease and those diagnosed through genetic screening. DESIGN: Cross‐sectional study....
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Abstract Gut microbiome transfer (GMT; also referred to as faecal microbiota transplantation or FMT) has been propelled from fringe therapy to mainstream science as a highly effective treatment for recurrent Clostridioides difficile infection. As a result, there has been great interest in the potential efficacy and safety of GMT in treating other medical conditions, for example, inflammatory bowel disease, and more recently as a novel therapy for obesity and metabolic diseases. For these chronic...
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Related ArticlesThe socioeconomic cost of chronic rhinosinusitis study. Rhinology. 2020 Mar 15;: Authors: Wahid NW, Smith R, Clark A, Salam M, Philpott CM Abstract INTRODUCTION: Chronic rhinosinusitis (CRS) is highly prevalent, affecting 11% of the population. Studies evaluating the socio-economic impact of CRS are mostly limited to the US population. Currently there is no study that has evaluated the socio-economic costs of CRS in the UK. METHODS:...
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Related ArticlesNutrition in RMDs: is it really food for thought? Focus on rheumatoid arthritis. BMC Rheumatol. 2020;4:10 Authors: Alunno A, Nikiphorou E, Philippou E, Daien C, Wiek D, Kouloumas M, Cutolo M Abstract Background: The relationship between food and health is known since the antiquity and in the field of rheumatic and musculoskeletal diseases (RMDs), mainly rheumatoid arthritis (RA), a large number of studies has been published over the last...
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Abstract To compare the local control and brain radionecrosis in patients with brain metastasis primarily treated by single-fraction radiosurgery (SRS) or hypofractionated stereotactic radiotherapy (HFSRT). Between January 2012 and December 2017, 179 patients with only 1–3 brain metastases (total: 287) primarily treated by SRS (14 Gy) or HFSRT (23.1 Gy in 3 fractions of 7.7 Gy, every other day) were retrospectively analyzed in a single center. Follow-up imaging data were available...
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"He Gave Us the Cornerstone of Sexual Medicine": A Nobel Plan but No Nobel Prize for Eugen Steinach.
Related Articles"He Gave Us the Cornerstone of Sexual Medicine": A Nobel Plan but No Nobel Prize for Eugen Steinach. Urol Int. 2020 Mar 13;:1-9 Authors: Hansson N, Krischel M, Södersten P, Moll FH, Fangerau H Abstract This paper reviews the files in the archive of the Nobel Prize Committee for Physiology or Medicine on the Austrian physiologist and pioneering researcher in the emerging fields of urology and sexual medicine: Eugen Steinach (1861-1944)....
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Related Articles[Effectiveness of medical treatment in the adult ADHD unit of Landspitali 2015-2017]. Laeknabladid. 2020 Mars;106(3):131-138 Authors: Bjarnadottir S, Olafsdottir H, Johnsen A, Haraldsson M, Sigurdsson E, Kjartansdottir SH Abstract BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder among children but symptoms may persist into adulthood. At Landspitali - the National University Hospital...
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Related ArticlesInterpersonal Psychotherapy Versus Cognitive Therapy for Depression: How They Work, How Long, and for Whom-Key Findings From an RCT. Am J Psychother. 2020 Mar 01;73(1):8-14 Authors: Lemmens LHJM, van Bronswijk SC, Peeters FPML, Arntz A, Roefs A, Hollon SD, DeRubeis RJ, Huibers MJH Abstract OBJECTIVE: Although the effectiveness of interpersonal psychotherapy (IPT) and cognitive therapy (CT) for major depression has been established, little...
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Related ArticlesApplicability of the 48/6 Model of Care as a Health Screening Tool, and its Association with Mobility in Community-Dwelling Older Adults. J Korean Med Sci. 2020 Feb 24;35(7):e43 Authors: Uhm KE, Oh-Park M, Kim YS, Park JM, Choi J, Moon Y, Han SH, Hwang JH, Lee KS, Lee J Abstract BACKGROUND: The 48/6 Model of Care is an integrative care initiative for improving the health outcomes of hospitalized older patients; however, its applicability...
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Related ArticlesThe role of anaesthesiologists in lethal injection: a call to action. Lancet. 2020 02 29;395(10225):749-754 Authors: Kim E, Levy RJ PMID: 32014115 [PubMed - indexed for MEDLINE]
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Related ArticlesCurrent Situation of Home Oxygen Therapy for Chronic Obstructive Pulmonary Disease Patients in Korea. J Korean Med Sci. 2020 Feb 03;35(4):e12 Authors: Kim JK, Jang SH, Park S, Kim JH, Park JY, Yoo KH, Kim YS, Lim SY, Hwang YI Abstract BACKGROUND: Long-term oxygen therapy provides various benefits, including prolonged survival for severely hypoxic chronic obstructive pulmonary disease (COPD) patients. However, adequate management strategies...
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Related ArticlesEstimating patient-reported outcomes for glaucoma management: A cross-sectional study. J Evid Based Med. 2020 Feb;13(1):8-16 Authors: Uruthiramoorthy L, Hutnik CML, Speechley KN, Malvankar-Mehta MS, Lizotte DJ Abstract AIM: To identify important explanatory variables of four patient-reported outcomes (PROs): vision-related quality of life (VRQoL), preference-based health-related quality of life (HRQoL), social support and community integration...
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Related ArticlesImpact of acute-on-chronic liver failure and decompensated liver cirrhosis on psychosocial burden and quality of life of patients and their close relatives. Health Qual Life Outcomes. 2020 Jan 13;18(1):10 Authors: Nagel M, Labenz C, Wörns MA, Marquardt JU, Galle PR, Schattenberg JM, Nguyen-Tat M Abstract BACKGROUND: Patients with liver cirrhosis often suffer from complications such as ascites, gastrointestinal bleeding, and infections,...
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Related ArticlesPsychometric properties of the Danish Hospital Anxiety and Depression Scale in patients with cardiac disease: results from the DenHeart survey. Health Qual Life Outcomes. 2020 Jan 07;18(1):9 Authors: Christensen AV, Dixon JK, Juel K, Ekholm O, Rasmussen TB, Borregaard B, Mols RE, Thrysøe L, Thorup CB, Berg SK Abstract BACKGROUND: Anxiety and depression symptoms are common among cardiac patients. The Hospital Anxiety and Depression Scale...
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Related ArticlesComparison of Effects of PELD and Fenestration in the Treatment of Geriatric Lumbar Lateral Recess Stenosis. Clin Interv Aging. 2019;14:2187-2194 Authors: Lv Z, Jin L, Wang K, Chen Z, Li F, Zhang Y, Lao L, Zhou C, Li X, Shen H Abstract Purpose: Although degenerative lumbar spinal stenosis (LSS) is increasingly being diagnosed in older people, there is much uncertainty about the appropriate operative treatment options. The objective of...
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Related ArticlesA Targeted Literature Review of the Disease Burden in Patients With Symptomatic Peripheral Artery Disease. Angiology. 2020 Apr;71(4):303-314 Authors: Bauersachs R, Debus S, Nehler M, Huelsebeck M, Balradj J, Bowrin K, Briere JB Abstract Patients with peripheral artery disease (PAD) have an increased risk of cardiovascular (CV) and limb events, but the disease is frequently underdiagnosed and treatment options are limited. This review...
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Related ArticlesThe power of touch: external applications from whole medical systems in the care of cancer patients (literature review). Support Care Cancer. 2020 Feb;28(2):461-471 Authors: Mühlenpfordt I, Stritter W, Bertram M, Ben-Arye E, Seifert G Abstract PURPOSE: In the context of whole medical systems (WMSs), external applications are manual treatments that stem from complementary medicine and are performed by practitioners, nurses and caregivers...
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Related ArticlesGEOFFREY HARRIS AWARD 2019: Translational research in pituitary tumours. Eur J Endocrinol. 2020 Jan;182(1):R1-R13 Authors: Stalla GK, Dimopoulou C, Jung-Sievers C, Arzt E, Paez Pereda M, Theodoropoulou M, Ciato D, Renner U Abstract Although effective treatment regimens (surgical resection, drug treatment with dopamine agonists or somatostatin analogues, radiotherapy) have been established for the therapy of most pituitary tumours, a considerable...
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Related ArticlesRole of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV. PLoS One. 2019;14(10):e0224322 Authors: Huang Y, Luo D, Chen X, Zhang D, Huang Z, Xiao S Abstract BACKGROUND: Psychosocial problems are common among people living with HIV (PLWH) and have been cross-sectionally associated with health-related quality of life (HRQoL). We evaluated the longitudinal...
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Related ArticlesSports Medicine Delivery Models: Legal Risks. J Athl Train. 2019 Dec;54(12):1237-1240 Authors: Rapp GC, Ingersoll CD Abstract Educational institutions sponsoring competitive athletics may use an athletics model, academic model, or medical model for delivery of sports medicine to student-athletes. Four types of legal risk are considered for these 3 models: litigation, contract, regulatory, and structural. The athletics model presents the...
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Related ArticlesLongitudinal analysis of quality of life in patients treated for differentiated thyroid cancer. Eur J Endocrinol. 2019 Dec;181(6):671-679 Authors: van Velsen EFS, Massolt ET, Heersema H, Kam BLR, van Ginhoven TM, Visser WE, Peeters RP Abstract Objective: Earlier cross-sectional studies showed that patients with differentiated thyroid cancer (DTC) have a significant reduction of quality of life (QoL) compared to controls. However, recent...
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Related ArticlesOrganizational justice and illness reporting among Japanese employees with chronic diseases. PLoS One. 2019;14(10):e0223595 Authors: Eguchi H, Tsutsumi A, Inoue A, Kachi Y Abstract PURPOSE: This study examined the association between perceived organizational justice (i.e., procedural justice and interactional justice) and reporting of illness to one's company (illness reporting) among Japanese employees with chronic diseases. ...
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Related ArticlesEffects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK. Nutrients. 2019 Oct 16;11(10): Authors: Klonizakis M, Grammatikopoulou MG, Theodoridis X, Milner M, Liu Y, Chourdakis M Abstract The beneficial effects of the Mediterranean diet (MD) adherence in reducing cardiovascular disease (CVD) risk and improving CVD-related physiological...
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Related ArticlesTelomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations. PLoS One. 2019;14(10):e0223891 Authors: Wan ES, Goldstein RL, Fan VS, Nguyen HQ, Hart JE, Garshick E, Orr EH, DeVivo I, Moy ML Abstract RATIONALE: Shorter leukocyte telomere length (LTL) is associated with reduced health-related quality of life and increased risk for acute exacerbations (AEs) and mortality in chronic obstructive...
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Related ArticlesTranslating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II. PLoS One. 2019;14(10):e0224068 Authors: Santoyo-Olsson J, Stewart AL, Samayoa C, Palomino H, Urias A, Gonzalez N, Torres-Nguyen A, Coleman L, Escalera C, Totten VY, Ortiz C, Nápoles AM Abstract OBJECTIVES: Adapt a cognitive-behavioral stress management program (Nuevo Amanecer or NA) to be generalizable to rural, low literacy...
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Related ArticlesDefining Global Benchmarks in Bariatric Surgery: A Retrospective Multicenter Analysis of Minimally Invasive Roux-en-Y Gastric Bypass and Sleeve Gastrectomy. Ann Surg. 2019 11;270(5):859-867 Authors: Gero D, Raptis DA, Vleeschouwers W, van Veldhuisen SL, Martin AS, Xiao Y, Galvao M, Giorgi M, Benois M, Espinoza F, Hollyman M, Lloyd A, Hosa H, Schmidt H, Garcia-Galocha JL, van de Vrande S, Chiappetta S, Menzo EL, Aboud CM, Lüthy SG, Orchard P, Rothe S,...
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Related ArticlesLate suture site complications of sacrospinous ligament fixation. Eur J Obstet Gynecol Reprod Biol. 2019 Nov;242:126-130 Authors: Hamdy MA, Ahmed WAS, Taha OT, Abolill ZM, Elshahat AM, Aboelroose AA Abstract STUDY OBJECTIVE: To evaluate the late suture- related complications of sacrospinous ligament fixation (SSLF) as a treatment for uterovaginal prolapse and their impact on the quality of life. DESIGN: A prospective cohort...
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Related ArticlesFactors associated with the use of diet and the use of exercise for prostate cancer by long-term survivors. PLoS One. 2019;14(10):e0223407 Authors: Hughes S, Egger S, Carle C, Smith DP, Chambers S, Kahn C, Caperchione CM, Moxey A, O'Connell DL Abstract OBJECTIVE: To assess the use of diet and the use of exercise for prostate cancer (and/or its treatments' side effects) by long-term survivors and whether such use is associated with selected...
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Related ArticlesAssociation of adrenal insufficiency with patient-oriented health-care outcomes in adult medical inpatients. Eur J Endocrinol. 2019 Dec;181(6):701-709 Authors: Ebrahimi F, Widmer A, Wagner U, Mueller B, Schuetz P, Christ-Crain M, Kutz A Abstract Objective: Adrenal insufficiency in the outpatient setting is associated with excess morbidity, mortality, and impaired quality of life. Evidence on its health-care burden in medical inpatients...
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Related ArticlesAbandonment of therapy in multidrug-resistant tuberculosis: Associated factors in a region with a high burden of the disease in Perú Biomedica. 2019 08 01;39(Supl. 2):44-57 Authors: Rivera O, Benites S, Mendigure J, Bonilla CA Abstract Introduction: In the context of multidrug-resistant tuberculosis, abandonment of therapy represents a serious public health problem that affects the quality of life of patients, families, and communities....
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Related ArticlesThe COPD multi-dimensional phenotype: A new classification from the STORICO Italian observational study. PLoS One. 2019;14(9):e0221889 Authors: Antonelli Incalzi R, Canonica GW, Scichilone N, Rizzoli S, Simoni L, Blasi F, STORICO study group Abstract BACKGROUND: This paper is aimed to (i) develop an innovative classification of COPD, multi-dimensional phenotype, based on a multidimensional assessment; (ii) describe the identified multi-dimensional...
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Related ArticlesMental health and quality of life outcomes in family members of patients with chronic critical illness admitted to the intensive care units of two Brazilian hospitals serving the extremes of the socioeconomic spectrum. PLoS One. 2019;14(9):e0221218 Authors: Fumis RRL, Ferraz AB, de Castro I, Barros de Oliveira HS, Moock M, Junior JMV Abstract Chronic critical illness (CCI) is a relevant clinical, social and financial health issue. The...
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Related ArticlesPhysical Therapists Needed: The Refugee Crisis in Greece and Our Ethical Responsibility to Respond. Phys Ther. 2019 12 16;99(12):1583-1586 Authors: Schottland-Cox J, Hartman J PMID: 31504927 [PubMed - indexed for MEDLINE]
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Related ArticlesAn Evidence-Based Perspective on Movement and Activity Following Median Sternotomy. Phys Ther. 2019 12 16;99(12):1587-1601 Authors: El-Ansary D, LaPier TK, Adams J, Gach R, Triano S, Katijjahbe MA, Hirschhorn AD, Mungovan SF, Lotshaw A, Cahalin LP Abstract Cardiac surgery via median sternotomy is performed in over 1 million patients per year worldwide. Despite evidence, sternal precautions in the form of restricted arm and trunk activity...
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Related ArticlesComments on "Commentary on: Why Should Young Aesthetic Plastic Surgeons Care About Aesthetic Medicine?" Aesthet Surg J. 2019 09 13;39(10):NP439 Authors: Breitbart AS PMID: 31504152 [PubMed - indexed for MEDLINE]
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Related ArticlesMindfulness- and acceptance-based interventions for patients with fibromyalgia - A systematic review and meta-analyses. PLoS One. 2019;14(9):e0221897 Authors: Haugmark T, Hagen KB, Smedslund G, Zangi HA Abstract OBJECTIVES: To analyze health effects of mindfulness- and acceptance-based interventions, including mindfulness-based stress reduction (MBSR), mindfulness-based cognitive therapy (MBCT) and acceptance and commitment therapy...
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Related ArticlesLactulose improves cognition, quality of life, and gut microbiota in minimal hepatic encephalopathy: A multicenter, randomized controlled trial. J Dig Dis. 2019 Oct;20(10):547-556 Authors: Wang JY, Bajaj JS, Wang JB, Shang J, Zhou XM, Guo XL, Zhu X, Meng LN, Jiang HX, Mi YQ, Xu JM, Yang JH, Wang BS, Zhang NP Abstract OBJECTIVE: Lactulose is effective in the treatment and prevention of overt hepatic encephalopathy (OHE), but there are...
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