Abstract Purpose The relationship between postoperative complications and long-term survival after surgery for esophageal squamous cell carcinoma (ESCC) is controversial. Method A total of 210 patients with ESCC who underwent subtotal esophagectomy with a reconstructed gastric tube were investigated according to the development of postoperative complications....
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Abstract Objective This article explores the differences in the effectiveness and safety of the treatment of bladder cancer (BC) by robotic-assisted radical cystectomy (RARC) and laparoscopic radical cystectomy (LRC). Methods A systematic search was performed using databases including Medline, PubMed and Web of Science within a limited period from January...
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Abstract Mammalian cells are inherently capable of sensing extracellular environmental signals and activating complex biological functions on demand. Advances in synthetic biology have made it possible to install additional capabilities, which can allow cells to sense the presence of custom biological molecules and provide defined outputs on demand. When implanted/infused in patients, such engineered cells can work as intrabody “doctors” that diagnose disease states and produce...
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Publication date: Available online 16 March 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mudry
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Publication date: 1 April 2020Source: Experimental Cell Research, Volume 389, Issue 1Author(s):
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Publication date: Available online 16 March 2020Source: Experimental Cell ResearchAuthor(s): Bailee H. Sliker, Benjamin T. Goetz, Raina Barnes, Hannah King, H. Carlo Maurer, Kenneth P. Olive, Joyce C. Solheim
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Related ArticlesThe Psychosocial Patient-Reported Outcomes of End of Pathway Cleft Surgery: A Systematic Review. Cleft Palate Craniofac J. 2020 Mar 16;:1055665620911328 Authors: Acum M, Mastroyannopoulou K, O'Curry S, Young J Abstract OBJECTIVE: To identify and review the literature on the psychosocial patient-reported outcomes (PROs) of surgery at the end of the cleft treatment pathway. DESIGN: A systematic literature search was performed using...
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Related ArticlesState-Mandated Coverage of Cleft Lip and Cleft Palate Treatment. Cleft Palate Craniofac J. 2020 Mar 16;:1055665620910529 Authors: Wanchek T, Wehby G Abstract OBJECTIVE: We conducted a comprehensive review of state laws and regulations that require private health insurance plans to cover the services needed by children born with cleft lip and/or cleft palate (CL/P). The goal is to better understand how states are reducing the barriers...
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Related ArticlesFamily Experience With Pierre Robin Sequence: A Qualitative Study. Cleft Palate Craniofac J. 2020 Mar 16;:1055665620910331 Authors: Skirko JR, Pollard SH, Slager S, Hung M, Weir C Abstract OBJECTIVE: To identify concepts and constructs important to parents of children with Pierre Robin Sequence (PRS). DESIGN: Qualitative study. SETTING: All children received some care at a tertiary hospital with additional care at outside...
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Abstract Sleep problems have a high prevalence and negative daytime consequences in adolescents. Current sleep measures for this age group have limitations. The Patient‐Reported Outcomes Measurement Information System (PROMIS®) developed sleep item banks for adults. In a previous validation study, these item banks were adapted to a shortened version for adolescents. The current study aimed to further explore the psychometric properties of the 11‐item Sleep‐Related Impairment and 23‐item Sleep Disturbance...
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JPM, Vol. 10, Pages 18: Dysmorphology in the Era of Genomic Diagnosis Journal of Personalized Medicine doi: 10.3390/jpm10010018 Authors: Hurst Robin Genetic and genomic testing technologies have expanded beyond levels of diagnostic capability that were unimaginable even a few years ago. While this has significantly benefited clinicians in their care of patients and families, it has also altered how geneticists evaluate patients. One immediate example is the role of the dysmorphologic...
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Abstract Purpose Lymphoproliferative disease in common variable immunodeficiency disease (CVID) is heterogeneous in pathogenesis and ranges from non-malignant lymphoid hyperplasia to lymphoma. Methods The United States Immunodeficiency Network (USIDNET) patient registry was queried for lymphoproliferative diseases reported in CVID patients. Diagnoses included...
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North America remains in the midst of an escalating opioid overdose epidemic, largely driven by the influx of synthetic opioids such a fentanyl and related analogues. High rates of mental illness among substan...
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A 60-year-old man presented with a 2-week history of pain and swelling in both knees, a 1-week history of pain and swelling in the left hand, and a 1-day history of inability to bear weight. His joint pain was associated with fatigue and stiffness, but he did not report having fever, gastrointestinal or genitourinary symptoms, or rash, and he also denied any history of trauma, previous episodes of joint pain, or surgery. He was not taking any relevant medications. He had a history of alcohol abuse...
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Immune checkpoint inhibitors are revolutionizing cancer treatment for many patients, alongside surgery, chemotherapy and radiotherapy.
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Abstract Many studies have focused on the significant role of biofilm formation by Bacillus in the biocontrol process. Bacillus pumilus HR10 is a plant growth-promoting rhizobacterium with multiple biocontrol functions, including promoting growth, controlling pathogens, and assisting in the formation of mycorrhizae. Currently, there is no relevant report on the biofilm formation of B. pumilus HR10 and its influencing factors. B. pumilus HR10 was found to easily form a stable biofilm...
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Background and Aims: Food frequency questionnaires (FFQ) have been widely used in epidemiologic studies since 1990s, but instruments need to be validated. The aim of this work was to create and assess the validity and reproducibility of an interview administered FFQ to be used in a Mexican women’s bone health cohort study, located in Monterrey city, Mexico. Methods: Validation of FFQ formed by 11 food groups and 136 food and beverage items was performed on 40–65-year-old Mexican women (n = 200) by...
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Introduction: The role of tea consumption on rheumatoid arthritis (RA) has been studied in recent years, but no clear conclusion has been drawn as a result of small sample size of the studies or the fact that only in vitro studies have been performed. Objectives: The aim of this study was to explore the possible association of tea consumption with RA through a large-scale, real-world study. Methods: A total of 733 RA patients were investigated from June to December, 2016. The disease activity of...
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Publication date: Available online 17 March 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Faustino Núñez-Batalla, Ana Belén Fernández-Junquera, Lorena Suárez-Villanueva, Estefanía Díaz-Fresno, Isabel Sandoval-Menéndez, Justo Gómez Martínez, José Luis Llorente-Pendás
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Publication date: Available online 17 March 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Lucía Prieto-Sánchez-de-Puerta, Emilio Domínguez-Durán, Ramón Moreno-Luna, Serafín Sánchez-Gómez
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Related ArticlesOver-expression of cyclo-oxygenase-2 predicts poor survival of patients with nasopharyngeal carcinoma: a meta-analysis. J Laryngol Otol. 2020 Mar 16;:1-6 Authors: Sim CC, Sim EU Abstract OBJECTIVES: The conclusive prognostic significance of cyclo-oxygenase-2 has been determined in various cancers but not in nasopharyngeal carcinoma. Therefore, this study aimed to evaluate the relationship of cyclo-oxygenase-2 expression with the survival...
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Related ArticlesEfficacy of small-volume gastrografin videofluoroscopic screening for detecting pharyngeal leaks following total laryngectomy. J Laryngol Otol. 2020 Mar 16;:1-4 Authors: Narayan M, Limbachiya S, Balasubramanian D, Subramaniam N, Thankappan K, Iyer S Abstract OBJECTIVES: Pharyngocutaneous fistulae are dreaded complications following total laryngectomy. This paper presents our experience using 3-5 ml gastrografin to detect pharyngeal leaks...
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Related ArticlesSafety of tympanoplasty and ossiculoplasty performed by otorhinolaryngology trainees. J Laryngol Otol. 2020 Mar 16;:1-6 Authors: Alzhrani F, Aldueb R, Alosaimi K, Islam T, Almuhawas F, Alsanosi A Abstract OBJECTIVE: This study aimed to examine the impact of trainee involvement in performing tympanoplasty or tympano-ossiculoplasty on outcomes. METHODS: A retrospective analysis was performed of a prospective database of all patients...
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Related ArticlesPost-rhinoplasty outcomes in an Indian population assessed using the FACE-Q appraisal scales: a prospective observational study. J Laryngol Otol. 2020 Mar 16;:1-5 Authors: Soni K, Patro SK, Aneja J, Kaushal D, Goyal A, Shakrawal N Abstract OBJECTIVES: The primary goal of rhinoplasty is patient satisfaction and improved quality of life. The present study was conducted to assess patient satisfaction with face and nose appearance, and quality...
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Zusammenfassung Eine intraoperative Diagnostik bei offenen gefäßchirurgischen Eingriffen sollte die diagnostische Sicherheit während der Operation erhöhen und eine Qualitätskontrolle darstellen mit dem Ziel, vermeidbare Komplikationen zu reduzieren. Die Evidenz der verschiedenen diagnostischen Verfahren hinsichtlich besserer postoperativer Ergebnisse ist jedoch sowohl für die Karotisendarteriektomie als auch die periphere Bypassanlage nicht gesichert. Dennoch ist eine intraoperative...
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Abstract Purpose While including amorphous solid dispersion (ASD) in tablet formulations is increasingly common, tablets containing high ASD loading are associated with slow disintegration, which presents a challenge to control pill burden for less potent compounds. Methods We use a model ASD, composed of a hydrophobic drug with copovidone and...
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Related ArticlesOvercoming frailty in recurrent and metastatic head and neck cancer. Oral Oncol. 2020 Mar 11;:104636 Authors: Szturz P, Vermorken JB PMID: 32171664 [PubMed - as supplied by publisher]
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Related ArticlesDiagnostic implications of miRNAs in Liquid Biopsy for Oral Squamous Cell Carcinoma (OSCC): Clinical validity and interpretation. Oral Oncol. 2020 Mar 11;:104634 Authors: Jayaraj R, Kumaraswamy C, Raymond G, Ravishankar Ram M, Govind SK, Chandramoorthy HC, Shaw P PMID: 32171663 [PubMed - as supplied by publisher]
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Publication date: Available online 16 March 2020Source: Cellular SignallingAuthor(s): Disha Hiregange, Hemanth Naick, Basuthkar J. Rao
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Publication date: Available online 16 March 2020Source: Cellular SignallingAuthor(s): Carolyn N. Brown, Daniel J. Atwood, Deepak Pokhrel, Kameswaran Ravichandran, Sara J. Holditch, Sanskriti Saxena, Makoto Miyazaki, Raphael Nemenoff, Mary C.M. Weiser-Evans, Danica Galesic Ljubanovic, Melanie S. Joy, Charles L. Edelstein
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Related ArticlesLack of impact of radiologic septal measurements upon patient symptoms and performance of septoplasty during endoscopic sinus surgery. Rhinology. 2020 Mar 16;: Authors: Rowan NR, Soler ZM, Mace JC, Camilon MP, Palmer C, Jones RH, Smith TL, Schlosser RJ Abstract BACKGROUND: Recent literature suggests that concurrent septoplasty during endoscopic sinus surgery (ESS) improves patient outcomes, however, the underlying indications for performing...
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Related ArticlesRetronasal olfactory testing using candies sent by post and for screening purposes: a feasibility study. Rhinology. 2020 Mar 16;: Authors: Besser G, Tianxiang Liu D, Prem B, Iabloncsik D, Pablik E, Mueller CA, Renner B Abstract BACKGROUND: The olfactory system is able to detect external odours through the orthonasal- and internal odours through the retronasal route. Flavour perception strongly relies on the sense of smell and this back...
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