Background As a fundamental process internalizing molecules from the plasma membrane, endocytosis plays a crucial role in podocyte biology. Our previous study has identified that overexpression of Myole may enhance podocyte endocytosis. However, its potential mechanism has been not well understand. Thus, we aimed to analyze whether albumin endocytosis by mouse glomerular podocytes is dependent on Myo1e expression. Also, we aimed to elucidate whether the underlying mechanism is mediated...
Tue Mar 17, 2020 02:00
Purpose The determinants of physical fitness in children have been given limited attention. In particular, the relative role of chronological age, sex, anthropometry, and body composition in physical fitness of children has been barely investigated. This cross-sectional study investigated determinants of physical fitness using a set of predictive variables including, in addition to chronological age and sex, a large panel of anthropometric measurements as well as body composition. The study was...
Tue Mar 17, 2020 02:00
Convolutional neural networks (CNNs) trained on natural images are extremely successful in image classification and localization due to superior automated feature extraction capability. In extending their use to biomedical recognition tasks, it is important to note that visual features of medical images tend to be uniquely different than natural images. There are advantages offered through training these networks on large scale medical common modality image collections pertaining to the recognition...
Tue Mar 17, 2020 02:00
The pikeperch (Sander lucioperca L.) possesses great potential for diversifying European aquaculture. However, studies on the genetic risk of stocking natural waters with farmed individuals of this species have been limited. Even the effect of pond culture on the genetic composition of stocks with natural-origin has not yet been determined. Our study aimed to compare the genetic variability of a wild living pikeperch population, a pond cultured broodstock (originating from the wild population) and...
Tue Mar 17, 2020 02:00
Background The arrival of many species of migrant passerine in the European spring has shifted earlier over recent decades, attributed to climate change and rising temperatures in Europe and west Africa. Few studies have shown the effects of climate change in both hemispheres though many long-distance migrants use wintering grounds which span Africa. The migrants’ arrival in Europe thus potentially reflects a combination of the conditions they experience across Africa. We examine...
Tue Mar 17, 2020 02:00
In light chain (LC) diseases, monoclonal immunoglobulin LCs are abundantly produced with the consequence in some cases to form deposits of a fibrillar or amorphous nature affecting various organs, such as heart and kidney. The factors that determine the solubility of any given LC in vivo are still not well understood. We hypothesize that some of the biochemical properties of the LCs that have been shown to correlate with amyloid fibril formation in patients also can be used as predictors for the...
Tue Mar 17, 2020 02:00
Artificial light at night is rapidly changing the sensory world. While evidence is accumulating for how insects are affected, it is not clear how this impacts higher trophic levels that feed on insect communities. Spiders are important insect predators that have recently been shown to have increased abundance in urban areas, but have shown mixed responses to artificial light. On a single bridge with alternating artificially lit and unlit sections, I measured changes in the orb-weaving spider Larinioides...
Tue Mar 17, 2020 02:00
Background WRKY proteins play a vital role in the plants response to different stresses, growth and development. Studies of WRKY proteins have been mainly focused on model plant Arabidopsis and a few other vegetable plants. However, the systematical study of eggplant WRKY transcription factor superfamily is scarce. Methods Bioinformatics has been used to identify and characterize the eggplant WRKY gene family. For the...
Tue Mar 17, 2020 02:00
Background The Orofacial Esthetic Scale (OES) is an instrument to assess an individual’s perception of their Orofacial Appearance (OA). However, its translation and evaluation of psychometric properties is necessary for its use in Brazilian individuals. Objectives To develop the Portuguese version of OES (OES-Pt), estimate its psychometric properties (validity, measurement invariance and reliability) when applied to Brazilian individuals aged 18–40 years, and estimate the relationship...
Tue Mar 17, 2020 02:00
Laugier–Hunziker syndrome is a rare, acquired disorder characterized by mucocutaneous hyperpigmentation and melanonychia striata with no underlying systemic abnormalities. We report an 8-year-old boy with Laugier–Hunziker syndrome who presented with melanonychia striata affecting all the fingernails and toenails, macular pigmentation on the tongue and the lower lip, and scleral melanocytosis. Melanonychia striata rarely affect all the twenty nails, and scleral melanocytosis has rarely been reported...
Tue Mar 17, 2020 07:05
Pediatric acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia (AML) that may be divided into two subgroups: (1) Down syndrome- (DS-) related AMKL which generally has a favorable prognosis and (2) non-DS-related AMKL which generally has a poorer outcome. We report a phenotypically normal child with AMKL with trisomy 21 (T21) and tetrasomy 21 clones. Subsequently, she was diagnosed with mosaic T21. She underwent reduced-intensity therapy with good outcome. We review the...
Tue Mar 17, 2020 06:35
Publication date: Available online 16 March 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Christoph Klug, Wolfgang Hemmer, Patricia Román-Carrasco, Margit Focke, Santiago Quirce, Teresa Boyano-Martínez, Erwin Gaubitzer, Herbert Wank, Ines Swoboda
Tue Mar 17, 2020 15:10
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Margaret H. Hastings, Jamie M. Gauthier, Kyle Mabry, Audrey Tran, Heng-Ye Man, Kathleen M. Kantak
Tue Mar 17, 2020 15:09
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Anna Skórzewska, Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Danuta Turzyńska, Alicja Sobolewska, Paweł Krząścik, Janusz Szyndler, Piotr Maciejak, Natalia Chmielewska, Karolina Kołosowska, Adam Płaźnik
Tue Mar 17, 2020 15:09
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Alexandra Gaillard, Susan L. Rossell, Sean P. Carruthers, Philip J. Sumner, Patricia T. Michie, William Woods, Erica Neill, Andrea Phillipou, Wei Lin Toh, Matthew E. Hughes
Tue Mar 17, 2020 15:09
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Maurizio Casarrubea, Fabiana Faulisi, Giulia Raso, Stefania Aiello, Giuseppe Crescimanno
Tue Mar 17, 2020 15:09
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Fatemeh Goshadrou, Bahman Sadeghi
Tue Mar 17, 2020 15:09
Publication date: Available online 16 March 2020Source: Behavioural Brain ResearchAuthor(s): Xiao Cai, Mingkun Ouyang, Yulong Yin, Qingfang Zhang
Tue Mar 17, 2020 15:09
Publication date: Available online 17 March 2020Source: Cancer/RadiothérapieAuthor(s): Bruce E. Ellerin, Carlo Greg N. Demandante, Joseph T. Martins
Tue Mar 17, 2020 15:01
Publication date: Available online 17 March 2020Source: Cancer/RadiothérapieAuthor(s): J. Bouter, J. Lacroix, J. Baud, J. Thariat
Tue Mar 17, 2020 15:01
Publication date: Available online 16 March 2020Source: Cancer/RadiothérapieAuthor(s): S. Yossi, D. Nguyen, S. Krhili, T. Lizée, M. Khodri
Tue Mar 17, 2020 15:01
Publication date: Available online 16 March 2020Source: Hearing ResearchAuthor(s): Maike Claußen, Jennifer Schulze, Hans Gerd Nothwang
Tue Mar 17, 2020 14:59
Publication date: Available online 16 March 2020Source: Medical HypothesesAuthor(s): Le Ji, Xiaoying Ma, Xiaoqian Dang, Wenchen Ji, Qichun Song, Shizhang Liu
Tue Mar 17, 2020 14:56
Publication date: Available online 16 March 2020Source: Medical HypothesesAuthor(s): Neil D. Theise, James M. Crawford, Yasuni Nakanuma, Alberto Quaglia
Tue Mar 17, 2020 14:56
Publication date: Available online 16 March 2020Source: Medical HypothesesAuthor(s): Ziad Ali, Autumn Roque, Rif S. El-Mallakh
Tue Mar 17, 2020 14:56
Publication date: Available online 16 March 2020Source: Medical HypothesesAuthor(s): Kemal Polat, Majid Nour
Tue Mar 17, 2020 14:56
Publication date: Available online 16 March 2020Source: Medical HypothesesAuthor(s): Takeshi Terao, Nobuyoshi Ishii, Hirofumi Hirakawa, Eiji Aoshima
Tue Mar 17, 2020 14:56
Mon Mar 16, 2020 04:57
Related ArticlesMetallic Hyperdensity Sign on Noncontrast CT Immediately after Mechanical Thrombectomy Predicts Parenchymal Hemorrhage in Patients with Acute Large-Artery Occlusion. AJNR Am J Neuroradiol. 2019 04;40(4):661-667 Authors: Xu C, Zhou Y, Zhang R, Chen Z, Zhong W, Gong X, Ding X, Lou M Abstract BACKGROUND AND PURPOSE: Parenchymal hemorrhage is a severe complication following mechanical recanalization in patients with acute ischemic stroke...
Tue Mar 17, 2020 14:54
Related ArticlesThe histone demethylase KDM2B activates FAK and PI3K that control tumor cell motility. Cancer Biol Ther. 2020 Mar 16;:1-8 Authors: Zacharopoulou N, Kallergi G, Alkahtani S, Tsapara A, Alarifi S, Schmid E, Sukkar B, Kampranis S, Lang F, Stournaras C Abstract Recent studies revealed that the histone demethylase KDM2B regulates the epithelial markers E-Cadherin and ZO-1, the RhoA/B/C-small-GTPases and actin cytoskeleton organization, in...
Tue Mar 17, 2020 14:43
Related ArticlesProspects of NSAIDs administration as double-edged agents against endometrial cancer and pathological species of the uterine microbiome. Cancer Biol Ther. 2020 Mar 15;:1-9 Authors: Kuźmycz O, Stączek P Abstract Many types of cancers, including endometrial cancer, were found to have cyclooxygenase-2 (COX-2) overexpression. Because this enzyme belongs to the group of pro-inflammatory enzymes, so-called NSAIDs (non-steroidal anti-inflammatory...
Tue Mar 17, 2020 14:43
Future Oncology, Ahead of Print.
Tue Mar 17, 2020 12:15
Publication date: Available online 16 March 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mudry
Tue Mar 17, 2020 14:27
Publication date: Available online 16 March 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Gerald Choon-Huat Koh, Helen Hoenig
Tue Mar 17, 2020 14:18
Abstract Many studies have focused on the significant role of biofilm formation by Bacillus in the biocontrol process. Bacillus pumilus HR10 is a plant growth-promoting rhizobacterium with multiple biocontrol functions, including promoting growth, controlling pathogens, and assisting in the formation of mycorrhizae. Currently, there is no relevant report on the biofilm formation of B. pumilus HR10 and its influencing factors. B. pumilus HR10 was found to easily form a stable biofilm...
Tue Mar 17, 2020 02:00
Related ArticlesImmediate effects of water resistance therapy on patients with vocal fold mass lesions. Eur Arch Otorhinolaryngol. 2020 Mar 14;: Authors: Echternach M, Raschka J, Kuranova L, Köberlein M, Richter B, Döllinger M, Kainz MA Abstract INTRODUCTION: Semi-occluded vocal tract exercises, such as water resistance therapy (WRT), are widely used in voice therapy. However, the potential positive effects of such a therapy on vocal fold oscillation...
Tue Mar 17, 2020 14:14
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