Nonsinusoidal oscillation techniques can shorten the negative strip time and improve the slab surface quality in the process of steel continuous casting. But the acceleration of nonsinusoidal oscillation is higher than that of the sinusoidal oscillation. So it is easy to result in the impact for the mold movement. To solve this problem, a nonsinusoidal oscillation waveform function of mold was constructed, which had good dynamic characteristics. And the smaller acceleration can reduce the impact...
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Magnetite and silica-coated magnetite (Fe3O4) nanoparticles (NPs) were synthesized by water-in-oil (W/O) microemulsion method from hydrated ferric nitrate, ferrous sulfate precursors and ammonia a precipitating agent with the assistance of Tween-80 and SDS surfactants. The synthesized materials were characterized by X-ray diffraction, scanning electron microscopy, thermal analyzer, and infrared spectroscopy. X-ray diffraction pattern of Fe3O4 showed that particles were phase pure with a cubic inverse...
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Capacitance aging of DC link capacitors in voltage source inverters (VSIs) is a common fault which can lead to instability of the DC voltage. In such a failure state, although the VSI can still work, its performance gradually deteriorates, resulting in a shorter service life of the equipment. Here, an online monitoring and fault diagnosis method for capacitance aging based on evidence reasoning (ER) rule is presented. Features from the DC link voltage data with different levels of capacitance aging...
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Enterotoxigenic Escherichia coli (ETEC) K88 is a zoonotic pathogen. Previous studies have shown that lactic acid bacteria (LAB) have great potential in promoting health and resisting pathogenic infections; however, relatively little research has been done on the Pediococcus genus of LAB. This study is aimed at exploring the mechanisms imparted by Pediococcus acidilactici P25 against ETEC K88 in Caenorhabditis elegans. The probiotic performance of P25 was investigated in vitro. Colonization of K88...
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Phospholipase D1 Ameliorates Apoptosis in Chronic Renal Toxicity Caused by Low-Dose Cadmium Exposure
Exposure to cadmium (Cd), a common heavy metal used in industry, can result in long-term chronic toxicity. It has been well characterized that kidneys are the main organs that are targeted by toxicity, which can cause apoptosis, necrosis, and atrophy of renal tubular epithelial cells. However, the molecular mechanisms associated with Cd toxicity remain unclear. In this study, the expression of renal proteins in Sprague-Dawley rats exposed to chronic Cd was analyzed with iTRAQ proteomics. Bioinformatics...
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Purpose. This study was performed to investigate the association of CEP55 expression with liver cancer and explore potential underlying mechanisms. Materials and Methods. Data obtained from The Cancer Genome Atlas (TCGA) was used to investigate CEP55 expression, its prognostic value, the potential mechanisms of its upregulation, CEP55-related pathways, and its biological functions in liver cancer. Data from Gene Expression Omnibus (GEO) and International Cancer Genome Consortium (ICGC) was used to...
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Systemic sclerosis can affect multiple internal organs, including the liver and lungs. Nintedanib, an antifibrotic approved for treatment of interstitial lung disease associated with systemic sclerosis, may have activity outside of the lungs. This study explored the effect of preventive and therapeutic nintedanib treatment in a 3-week carbon tetrachloride (CCL4)-induced (500 mg/kg/day twice weekly for 3 weeks) model of hepatic inflammation and fibrosis in C57Bl/6 mice (aged 8 weeks, per group)....
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This paper considers a new method to solve the first-order and second-order nonhomogeneous generalized Sylvester matrix equations and , respectively, where , and are the arbitrary real known matrices and and are the matrices to be determined. An explicit solution for these equations is proposed, based on the orthogonal reduction of the matrix to an upper Hessenberg form . The technique is very simple and does not require the eigenvalues of matrix to be known. The proposed method is illustrated...
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In many real-world fault diagnosis applications, due to the frequent changes in working conditions, the distribution of labeled training data (source domain) is different from the distribution of the unlabeled test data (target domain), which leads to performance degradation. In order to solve this problem, an end-to-end unsupervised domain adaptation bear fault diagnosis model that combines Riemann metric correlation alignment and one-dimensional convolutional neural network (RMCA-1DCNN) is proposed...
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Mathematical models can aid in elucidating the spread of infectious disease dynamics within a given population over time. In an attempt to model tuberculosis (TB) dynamics among high-burden districts in the Ashanti Region of Ghana, the SEIR epidemic model with demography was employed within both deterministic and stochastic settings for comparison purposes. The deterministic model showed success in modelling TB infection in the region to the transmission dynamics of the stochastic SEIR model over...
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Drug-induced immune haemolytic anaemia (DIIHA) is extremely rare. We herein report a case of DIIHA due to co-amoxiclav. A 53-year-old male being treated for left-sided pyelonephritis with intravenous co-amoxiclav developed symptoms and signs of anaemia on the third day of treatment. He was found to have evidence of haemolysis with a positive Coombs test and IgG antibodies and C3d. Co-amoxiclav was identified as the probable culprit, using the Naranjo adverse drug reaction probability scale. Upon...
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Background. Healthcare-associated infection is a major public health problem, in terms of mortality, morbidity, and costs. Majorities of the cause of these infections were preventable. Understanding the potential risk factors is important to reduce the impact of these avoidable infections. The study was aimed to identify factors associated with healthcare-associated infections among patients admitted at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia. Methods. A cross-sectional...
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Interleukin-6 (IL-6) plays an essential function in the development of rheumatoid arthritis (RA), mainly through its proinflammatory effect, which may lead to joint destruction. The genes encoding IL-6 receptor (IL6R) and suppressor of cytokine signaling 3 (SOCS3) play a key role in the IL-6 signaling pathway, but their epigenetic regulation remains unclear. The aim of the study was to investigate how the presence of methylation in the SOCS3 and IL6R promoters is associated with the morbidity and...
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Conservation tillage has many advantages in crop production and weed control management. N-residue of hairy vetch as a green manure cover crop through tillage and no-tillage practices may increase inorganic-N level in soils and contribute to sustainable agriculture. Prior to corn cultivation, hairy vetch was cut after growing in the pots for 103 days. Six treated soils were prepared for no-tillage treatments (SRN, RN, and CN) and for tillage treatments (SRT, RT, and CT), where the soils were treated...
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In recent years, various biomarkers have been gradually applied on bronchoalveolar lavage (BAL) fluid for the diagnosis of invasive pulmonary aspergillosis (IPA). The objective of this study is to assess the value of the liquid-based cytopathology test (LCT) for improving the identification of IPA in BAL fluid from possible IPA patients, following special staining with periodic acid-Schiff staining (PAS) or Grocott’s methenamine silver (GMS). A total of 47 consecutive possible IPA patients who underwent...
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Background. It is currently impossible to diagnose Parkinson’s disease (PD) in the premotor phase even though at the time of motor symptom onset the number of already degenerated dopaminergic substantia nigra neurons is considerable. Degeneration of the dorsal nucleus of the vagus nerve (VN) has been reported early in the disease course, and it could lead to impaired function of the VN, resulting in certain nonmotor symptoms of PD. Therefore, we raised a hypothesis that the loss of VN neurons could...
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Introduction. Acute mesenteric ischemia, although rare, is associated with numerous complications and death. This work presents acute mesenteric ischemia treatment based on an analysis of various management strategies and identifies prognostic factors that influence therapy effectiveness. Material and Methods. We conducted a retrospective analysis of all patients who were diagnosed with acute mesenteric ischemia due to occlusion and hospitalized between January 1, 2002, and December 31, 2018. Results....
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Background and Aims. Linked color imaging (LCI) helps screen and diagnose for early gastric cancer by color contrast in different mucosa. RGB (red, green, and blue) pixel brightness quantifies colors, which is relatively objective. Limited studies have combined LCI images with RGB to help screen for early gastric cancer (EGC). We aimed to evaluate the RGB pixel brightness characteristics of EGC and noncancer areas in LCI images. Methods. We retrospectively reviewed early gastric cancer (EGC) patients...
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In this paper, the time-fractional Fujimoto–Watanabe equation is investigated using the Riemann–Liouville fractional derivative. Symmetry groups and similarity reductions are obtained by virtue of the Lie symmetry analysis approach. Meanwhile, the time-fractional Fujimoto–Watanabe equation is transformed into three kinds of reduced equations and the third of which is based on Erdélyi–Kober fractional integro-differential operators. Furthermore, the conservation laws are also acquired by Ibragimov’s...
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Foot and mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals and one of the endemic diseases in Ethiopia. The study was aimed to estimate the seroprevalence and to assess associated risk factors of foot and mouth disease seroprevalence in West Shewa Zone. A total of 384 sera samples were collected from randomly selected cattle and tested using ELISA for antibodies against nonstructural proteins of foot and mouth disease viruses based on IDEXX FMD Multispecies Ab Test...
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Groundnut yields obtained by farmers in northern Ghana are generally low due to low soil fertility resulting from continuous cropping coupled with low use of external inputs. There is therefore the need to use systems’ internal resources such as biological nitrogen fixation efficiently to enhance crop production. This on-station experiment investigated nodulation and pod yield responses of three groundnut varieties, namely Obolo, Oboshie and Samnut 22 to inoculation with rhizobium inoculants of exotic...
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Objective. The deceleration capacity (DC) and acceleration capacity (AC) of heart rate, which are recently proposed variants to the heart rate variability, are calculated from unevenly sampled RR interval signals using phase-rectified signal averaging. Although uneven sampling of these signals compromises heart rate variability analyses, its effect on DC and AC analyses remains to be addressed. Approach. We assess preprocessing (i.e., interpolation and resampling) of RR interval signals on the diagnostic...
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Rapid land use changes have been observed in recent years in central Ethiopia. The shift from natural ecosystem to artificial ecosystem is the main direction of change. Therefore, this study was initiated to assess the effects of land use types on selected soil properties in Meja watershed, central highlands of Ethiopia. The randomized complete block design, including three adjacent land use types as treatments with three replications and two soil depths (0–15 and 15–30 cm), was applied in this study....
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A model test and finite element analysis were conducted in this study to determine the distribution law of shear lag effect in the main beam section, a box girder, during the cable-stayed bridge construction process. The experimental and theoretical results were compared in an example of loading the control section. The stress value of the cable tension area of the main beam upper edge was found to markedly change when tensiling the cable force and was accompanied by prominent shear lag effect. After...
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Surfactants can improve the wetting performance of the dust-reduction spraying water, thus improving the dust-reduction effect by spray. In this study, the performance of surfactant solution in wetting coal dust was investigated through experiments. In addition, the effects of surfactant type, mass fraction, metamorphic degree of coal, particle size, and additives were investigated. According to the results of surface tension experiments, the surface tension of the solution decreased with the increase...
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The structural factor of samples microplasticity deposited with carbon steel construction tapes in connection with the different sensitivities of the deposited metal to stress concentration was investigated. The most favorable structure of the deposited layer, which is characterized by low sensitivity to stress concentration, is found. The combined technology of parts recovery modes operating in stress factor conditions is given. The covering agent composition, which allows to reduce the energy consumption...
7h
Avian infectious bronchitis virus (IBV) is an evolving and dynamic virus that causes major economic losses for the poultry industry worldwide. Continuous evolution and emergence of new variants of this virus are the major challenges for controlling the disease with routine vaccination. Successful vaccination usually requires the use of a homologous vaccine, which in turn necessitates continuous investigation of the circulating strains. Herein, we performed a reverse transcriptase-polymerase chain...
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Purpose. To evaluate the serum level of angiotensin-converting enzyme (ACE) as an important component of the renin-angiotensin system (RAS) in optic neuritis (ON) compared to the healthy control group in the context investigating the possible role of ACE in ON pathogenesis. Methods. This case-control study was conducted on patients with ON and healthy controls. Serum ACE levels were assessed and compared between the two groups by using commercially available kits by ELISA for ACE. Results. Sixty-five...
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This study aimed to determine phytochemical contents, antibacterial properties, and antibiotic modulating potential of Punica granatum leaf extracts: hexane, chloroform, ethyl acetate, ethanol, and aqueous extracts as well as an extract enriched with total oligomer flavonoids (TOFs). The TOF extract contained the highest value of phenols and flavonoids. Rutin, luteolin, gallic acid, and ellagic acid were determined by HPLC analysis of this extract. The antibacterial activity was assayed by the disc...
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In this study, we determine the curative effects of okra pods (Abelmoschus esculentus L.) extract against lead acetate toxicity in mice kidney. n-Hexane, ethyl acetate, and methanol solvent were used for extracting okra pods. The role of the extract as an antioxidant was tested by DPPH and FRAP methods. The methanol extract was used for experiments in animals. A total of 30 male BALB/c mice were randomly divided into six equal groups: normal control, negative control (lead-induced), and treatment...
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Comparative analyses of diversity and similarity indices of west bank and block A forest of the International Institute of Tropical Agriculture (IITA) were carried out by the vegetation survey using transects and plot sampling techniques. Six transects {A (270°W), B (90°E), C (180°S), D, E (0°N), and F (180°W)} were constructed with the aid of prismatic compass in west bank forest and block A forest. 10 sampling plots of 10 m × 10 m were demarcated along each transect making 30 plots in each forest,...
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The KCNJ2 gene mutations induce short QT syndrome (SQT3) by directly increasing the IK1 current. There have been many studies on the electrophysiological effects of mutations such as the KCNJ2 D172N that cause the SQT3. However, the KCNJ2 E299V mutation is distinguished from other representative gene mutations that can induce the short QT syndrome (SQT3) in that it increased IK1 current by impairing the inward rectification of K+ channels. The studies of the electromechanical effects on myocardial...
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Background. Reference interval (RI) research is to make it a concise, effective, and practical diagnostic tool. This study aimed to establish sex- and age-specific RI for myocardial enzyme activity in population aged 1–
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Background. Clinical pharmacy is a branch of health sciences that focuses more on the patient than on drug product-oriented services to optimize drug therapy. This study aimed to assess attitudes, opportunities, and challenges for clinical pharmacy services from the health care providers’ perspective in Mizan-Tepi University Teaching Hospital. Methods. A cross-sectional study was conducted among physicians, nurses, pharmacy professionals, and public health officers working in Mizan-Tepi University...
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Structural characteristics of local saline-alkali soil in the Yellow River Delta were studied by microscopic test methods of liquid nitrogen vacuum freeze-drying machine, fully automatic mercury intrusion porosimetry, X-ray diffractometer, and high- and low-vacuum scanning electron microscope. Permeability of the saline-alkali soil belongs to two grades of micropermeable water and extremely micropermeable water. Average volume ratio of pores with diameters no more than 2 μm is 86.25%; therefore,...
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Piriformis syndrome is a rare syndrome which is one of the main causes of nondiscogenic sciatica causing severe low back pain due to entrapment of sciatic nerve either by the hypertrophy or by inflammation of the piriformis muscle. We have carried out dissection in 20 Nepalese cadavers. Out of 40 dissected gluteal regions, 37 exhibited typical appearance of sciatic nerve, piriformis muscle, and their relations resembling type-a, whereas 3 gluteal regions showed composite structural variations resembling...
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Aging building structure has become a world problem. This problem is particularly serious in developing and underdeveloped countries. The multihazard resilience and sustainability (e.g., seismic performance) decrease at the aging building. A construction method for strengthening aging-reinforced concrete buildings by wrapping structural members with carbon fiber sheets has been proposed and implemented in recent years. Authors aim to develop a seismic retrofitting method of aging concrete structural...
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Injection molding is one of the most significant material processing methods for mass production of plastic products. It is widely used in various industry sectors, and its products are ubiquitous in our daily life. The settings and optimization of the injection molding process dictate the geometric precision and mechanical properties of the final products. Therefore, sensing, optimization, and control of the injection molding process have a crucial influence on product quality and have become an...
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Local inclusion topography has significant influence on seismic wave propagation, and the propagation characteristics of seismic waves in poroelastic soils are obviously different from those in single-phase media. Based on Biot’s theory, the scattering of plane P1 wave by inclusion in a three-dimensional poroelastic half-space is studied by using the indirect boundary element method (IBEM). The scattering field is constructed by introducing a virtual wave near the interface between inclusion and...
7h
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