Molecules, Vol. 25, Pages 1599: Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of Their in vitro Antiproliferative Effects Molecules doi: 10.3390/molecules25071599 Authors: Fodor Hutai Jernei Takács Szász Sulyok-Eiler Harmat Oláh Szabó Schlosser Hudecz Kőhidai Csámpai Use of a Pictet-Spengler...
Molecules, Vol. 25, Pages 1600: A Hydrophilic Interaction Liquid Chromatography–Tandem Mass Spectrometry Quantitative Method for Determination of Baricitinib in Plasma, and Its Application in a Pharmacokinetic Study in Rats Molecules doi: 10.3390/molecules25071600 Authors: Essam Ezzeldin Muzaffar Iqbal Yousif A. Asiri Azza A Ali Prawez Alam Toqa El-Nahhas Baricitinib, is a selective and reversible Janus kinase inhibitor, is commonly used to treat adult patients with moderately...
Molecules, Vol. 25, Pages 1601: Changes in the Content of Phenolic Compounds and Biological Activity in Traditional Mexican Herbal Infusions with Different Drying Methods Molecules doi: 10.3390/molecules25071601 Authors: Sandra N. Jimenez-Garcia Moisés A. Vazquez-Cruz Xóchitl S. Ramirez-Gomez Vicente Beltran-Campos Luis M. Contreras-Medina Juan F. Garcia-Trejo Ana A. Feregrino-Pérez Mexican spices are used in the supplementation of the human diet and as medicinal herbs...
Molecules, Vol. 25, Pages 1597: Rifamycin O, An Alternative Anti-Mycobacterium abscessus Agent Molecules doi: 10.3390/molecules25071597 Authors: Bui Thi Bich Hanh June-Woo Park Tae Ho Kim Jae-Sung Kim Chul-Su Yang Kiseok Jang Jinsheng Cui Dong-Chan Oh Jichan Jang Mycobacterium abscessus is the most difficult-to-treat nontuberculous mycobacteria because of its resistance to many antibiotics. In this study, we screened the Korea Chemical Bank library for a bioluminescent...
Molecules, Vol. 25, Pages 1596: Pre-Clinical Investigation of Keratose as an Excipient of Drug Coated Balloons Molecules doi: 10.3390/molecules25071596 Authors: Emily Goel Megan Erwin Claire V. Cawthon Carson Schaff Nathaniel Fedor Trevor Rayl Onree Wilson Uwe Christians Thomas C. Register Randolph L. Geary Justin Saul Saami K. Yazdani Background: Drug-coated balloons (DCBs), which deliver anti-proliferative drugs with the aid of excipients, have emerged...
Molecules, Vol. 25, Pages 1595: Lecithin-Based Dermal Drug Delivery for Anti-Pigmentation Maize Ceramide Molecules doi: 10.3390/molecules25071595 Authors: Kazuhiro Kagotani Hiroko Nakayama Liqing Zang Yuki Fujimoto Akihito Hayashi Ryoji Sono Norihiro Nishimura Yasuhito Shimada Ceramides have several well-known biological properties, including anti-pigmentation and anti-melanogenesis, which make them applicable for use in skincare products in cosmetics. However, the...
Molecules, Vol. 25, Pages 1594: Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis Molecules doi: 10.3390/molecules25071594 Authors: Xunan Zheng Wei Liu Dawei Zhang Oxazole compounds, including one nitrogen atom and one oxygen atom in a five-membered heterocyclic ring, are present in various biological activities. Due to binding with a widespread spectrum of receptors and enzymes easily in biological systems through various non-covalent...
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Nanomaterials, Vol. 10, Pages 652: Design and Testing of Bistable Lattices with Tensegrity Architecture and Nanoscale Features Fabricated by Multiphoton Lithography Nanomaterials doi: 10.3390/nano10040652 Authors: Vangelatos Micheletti P. Grigoropoulos Fraternali A bistable response is an innate feature of tensegrity metamaterials, which is a conundrum to attain in other metamaterials, since it ushers unconventional static and dynamical mechanical behaviors. This paper investigates...
Nanomaterials, Vol. 10, Pages 649: Transcriptome Profiling and Toxicity Following Long-Term, Low Dose Exposure of Human Lung Cells to Ni and NiO Nanoparticles—Comparison with NiCl2 Nanomaterials doi: 10.3390/nano10040649 Authors: Anda R. Gliga Sebastiano Di Bucchianico Emma Åkerlund Hanna L. Karlsson Production of nickel (Ni) and nickel oxide (NiO) nanoparticles (NPs) leads to a risk of exposure and subsequent health effects. Understanding the toxicological effects and underlying...
Nanomaterials, Vol. 10, Pages 651: Pillararenes Trimer for Self-Assembly Nanomaterials doi: 10.3390/nano10040651 Authors: Zhang Liu Fu Pillararenes trimer with particularly designed structural geometry and excellent capacity of recognizing guest molecules is a very efficient and attractive building block for the fabrication of advanced self-assembled materials. Pillararenes trimers could be prepared via both covalent and noncovalent bonds. The classic organic synthesis reactions...
Nanomaterials, Vol. 10, Pages 650: Pressure Induced Stability Enhancement of Cubic Nanostructured CeO2 † Nanomaterials doi: 10.3390/nano10040650 Authors: Mariano Andrés Paulin Gaston Garbarino Ana Gabriela Leyva Mohamed Mezouar Joaquin Sacanell Ceria (CeO2)-based materials are widely used in applications such as catalysis, fuel cells and oxygen sensors. Its cubic fluorite structure with a cell parameter similar to that of silicon makes it a candidate for implementation in...
Nanomaterials, Vol. 10, Pages 648: Formation of Thin NiGe Films by Magnetron Sputtering and Flash Lamp Annealing Nanomaterials doi: 10.3390/nano10040648 Authors: Viktor Begeza Erik Mehner Hartmut Stöcker Yufang Xie Alejandro García Rene Hübner Denise Erb Shengqiang Zhou Lars Rebohle The nickel monogermanide (NiGe) phase is known for its electrical properties such as low ohmic and low contact resistance in group-IV-based electronics. In this work, thin films of...
Nanomaterials, Vol. 10, Pages 647: Cooling Performance of a Novel Circulatory Flow Concentric Multi-Channel Heat Sink with Nanofluids Nanomaterials doi: 10.3390/nano10040647 Authors: Ravindra Jilte Mohammad H. Ahmadi Ravinder Kumar Vilas Kalamkar Amirhosein Mosavi Heat rejection from electronic devices such as processors necessitates a high heat removal rate. The present study focuses on liquid-cooled novel heat sink geometry made from four channels (width 4 mm and depth...
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Nutrients, Vol. 12, Pages 969: Role of Vitamin D in Preventing and Treating Selected Extraskeletal Diseases—An Umbrella Review Nutrients doi: 10.3390/nu12040969 Authors: Friederike Maretzke Angela Bechthold Sarah Egert Jana B. Ernst Debora Melo van Lent Stefan Pilz Jörg Reichrath Gabriele I. Stangl Peter Stehle Dorothee Volkert Michael Wagner Julia Waizenegger Armin Zittermann Jakob Linseisen Evidence is accumulating that vitamin D may have beneficial...
Nutrients, Vol. 12, Pages 967: In Vitro Characterization, Modelling, and Antioxidant Properties of Polyphenon-60 from Green Tea in Eudragit S100-2 Chitosan Microspheres Nutrients doi: 10.3390/nu12040967 Authors: Souto da Ana Souto Zielińska Marques Andrade Horbańczuk Atanasov Lucarini Durazzo Silva Novellino Santini Severino Eudragit S100-coated chitosan microspheres (S100Ch) are proposed as a new oral delivery system for green tea...
Nutrients, Vol. 12, Pages 968: Increasing Food Expenditure in Long Day-care by an Extra $0.50 per Child/Day Would Improve Core Food Group Provision Nutrients doi: 10.3390/nu12040968 Authors: Sambell Wallace Lo Costello Devine Early childhood education and care services are a significant feature of Australian family life, where nearly 1.4 million children attended a service in 2019. This paper reports on the cost of food provided to children in long day-care (LDC) services...
Nutrients, Vol. 12, Pages 966: Salivary Microbiota Shifts under Sustained Consumption of Oolong Tea in Healthy Adults Nutrients doi: 10.3390/nu12040966 Authors: Zhibin Liu Hongwen Guo Wen Zhang Li Ni Tea is the most widely consumed beverages next to water, however little is known about the influence of sustained tea consumption on the oral bacteria of healthy adults. In this study, three oral healthy adults were recruited and instructed to consume 1.0 L of oolong tea infusions...
Nutrients, Vol. 12, Pages 965: MK-7 and Its Effects on Bone Quality and Strength Nutrients doi: 10.3390/nu12040965 Authors: Toshiro Sato Naoko Inaba Takatoshi Yamashita Vitamin K acts as a cofactor and is required for post-translational γ-carboxylation of vitamin K-dependent proteins (VKDP). The current recommended daily intake (RDI) of vitamin K in most countries has been established based on normal coagulation requirements. Vitamin K1 and menaquinone (MK)-4 has been...
Nutrients, Vol. 12, Pages 964: The Effects of Foods Embedded in Entertainment Media on Children’s Food Choices and Food Intake: A Systematic Review and Meta-Analyses Nutrients doi: 10.3390/nu12040964 Authors: Victoria Villegas-Navas Maria-Jose Montero-Simo Rafael A. Araque-Padilla While watching or playing with media, children are often confronted with food appearances. These food portrayals might be a potential factor that affects a child’s dietary behaviors. We aimed to comprehensively...
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Particles, Vol. 3, Pages 245-271: Effective Field Theories Particles doi: 10.3390/particles3020020 Authors: Andrey Grozin This paper represents a pedagogical introduction to low-energy effective field theories. In some of them, heavy particles are “integrated out” (a typical example—the Heisenberg–Euler EFT); in some, heavy particles remain but some of their degrees of freedom are “integrated out” (Bloch–Nordsieck...
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Pathogens, Vol. 9, Pages 256: A qPCR-Based Survey of Haplosporidium nelsoni and Perkinsus spp. in the Eastern Oyster, Crassostrea virginica in Maine, USA Pathogens doi: 10.3390/pathogens9040256 Authors: Marquis Bishop Record Countway Fernández Robledo Eastern oyster (Crassostrea virginica) aquaculture is increasingly playing a significant role in the state of Maine’s (USA) coastal economy. Here, we conducted a qPCR-based survey for Haplosporidium nelsoni,...
Pathogens, Vol. 9, Pages 255: Modeling of the HIV-1 Life Cycle in Productively Infected Cells to Predict Novel Therapeutic Targets Pathogens doi: 10.3390/pathogens9040255 Authors: Olga Shcherbatova Dmitry Grebennikov Igor Sazonov Andreas Meyerhans Gennady Bocharov There are many studies that model the within-host population dynamics of Human Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell replication of HIV-1 remains to be not comprehensively...
Pathogens, Vol. 9, Pages 254: The Neuropathic Itch Caused by Pseudorabies Virus Pathogens doi: 10.3390/pathogens9040254 Authors: Kathlyn Laval Lynn W. Enquist Pseudorabies virus (PRV) is an alphaherpesvirus related to varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV1). PRV is the causative agent of Aujeskzy’s disease in swine. PRV infects mucosal epithelium and the peripheral nervous system (PNS) of its host where it can establish a quiescent, latent infection....
Pathogens, Vol. 9, Pages 253: Histochemical and Microscopic Studies Predict that Grapevine Genotype “Ju mei gui” is Highly Resistant against Botrytis cinerea Pathogens doi: 10.3390/pathogens9040253 Authors: Mati Ur Rahman Qingqing Ma Bilal Ahmad Muhammad Hanif Youlin Zhang The necrotrophic fungus Botrytis cinerea causes devastating pre- and post-harvest yield losses in grapevine (Vitis vinifera L.). Although B. cinerea has been well-studied in different plant species, there...
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Pharmaceutics, Vol. 12, Pages 310: Scaling Tableting Processes from Compaction Simulator to Rotary Presses—Mind the Sub-Processes Pharmaceutics doi: 10.3390/pharmaceutics12040310 Authors: Isabell Wünsch Irene Friesen Daniel Puckhaber Thomas Schlegel Jan Henrik Finke Compaction simulators are frequently used in the formulation and process development of tablets, bringing about the advantages of flexibility, low material consumption, and high instrumentation to generate the...
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Pharmacy, Vol. 8, Pages 58: Enhancing Pharmaceutical Packaging through a Technology Ecosystem to Facilitate the Reuse of Medicines and Reduce Medicinal Waste Pharmacy doi: 10.3390/pharmacy8020058 Authors: Terence K. L. Hui Bilal Mohammed Parastou Donyai Rachel McCrindle R. Simon Sherratt Background: The idea of reusing dispensed medicines is appealing to the general public provided its benefits are illustrated, its risks minimized, and the logistics resolved. For example,...
Pharmacy, Vol. 8, Pages 56: A Comprehensive Evaluation of Studies on the Adverse Effects of Medications in Australian Aged care Facilities: A Scoping Review Pharmacy doi: 10.3390/pharmacy8020056 Authors: Haider Qasim Maree Simpson Yann Guisard Barbora de Courten Aim: this scoping review was designed to identify studies that assess adverse drug reactions (ADRs) for older people in Australian aged care facilities. This review critically evaluates each published study to identify...
Pharmacy, Vol. 8, Pages 57: Systematic Medication Review in General Practice by an Interdisciplinary Team: A thorough but Laborious Method to Address Polypharmacy among Elderly Patients Pharmacy doi: 10.3390/pharmacy8020057 Authors: Dalin Vermehren Jensen Unkerskov Andersen Polypharmacy increases the risk of hospitalization but may be reduced by medication review. The study objective is to describe and evaluate a method for conducting medication review in general practice...
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Plants, Vol. 9, Pages 429: Nematicidal Amendments and Soil Remediation Plants doi: 10.3390/plants9040429 Authors: Nikoletta Ntalli Zbigniew Adamski Maria Doula Nikolaos Monokrousos The intensification of agriculture has created concerns about soil degradation and toxicity of agricultural chemicals to non-target organisms. As a result, there is great urgency for discovering new ecofriendly tools for pest management and plant nutrition. Botanical matrices and their extracts and...
Plants, Vol. 9, Pages 428: Separation of New Coumarin Glycosides from Toddalia asiatica Using Offline Two-Dimensional High-Performance Liquid Chromatography Plants doi: 10.3390/plants9040428 Authors: Li Sun Zhang Liu Liu Zhang Wang Wang Wang Coumarins and flavonoids are the major constituents of Toddalia asiatica. The separation and purification of ingredients from T. asiatica is an important procedure to acquire high-purity compounds for subsequent pharmacological...
Plants, Vol. 9, Pages 426: Citrus Polyamines: Structure, Biosynthesis, and Physiological Functions Plants doi: 10.3390/plants9040426 Authors: Nabil Killiny Yasser Nehela Polyamines (PAs) are ubiquitous biogenic amines found in all living organisms from bacteria to Archaea, and Eukaryotes including plants and animals. Since the first description of putrescine conjugate, feruloyl-putrescine (originally called subaphylline), from grapefruit leaves and juice, many research studies have...
Plants, Vol. 9, Pages 427: Pathological and Epidemiological Characterization of First Outbreak of Daylily Rust in Europe and Evaluation of Puccinia hemerocallidis Resistance in Hemerocallis Cultivars Plants doi: 10.3390/plants9040427 Authors: Ramos Carvalho Soares da Silva Ramos Talhinhas Daylily rust—caused by Puccinia hemerocallidis—was confined to Eastern Asia until the disease was reported in Oceania, Africa, the Americas and Portugal in the 21st...
Plants, Vol. 9, Pages 424: Colchicine-Induced Polyploidy in Rhododendron fortunei Lindl Plants doi: 10.3390/plants9040424 Authors: Lan Mo Junhao Chen Xiongzhen Lou Qiangwei Xu Renhui Dong Zaikang Tong Huahong Huang Erpei Lin Polyploidy in Rhododendron fortunei has great potential to improve its horticultural and commercial value, and to also meet market demands. In this study, a feasible method for polyploid induction in R. fortunei via colchicine treatment was established,...
Plants, Vol. 9, Pages 425: Hydrothermal Carbonization and Pellet Production from Egeria densa and Lemna minor Plants doi: 10.3390/plants9040425 Authors: Xana Álvarez Ángeles Cancela Vanesa Freitas Enrique Valero Ángel Sánchez Carolina Acuña-Alonso Biofuels are seen as a potential option for mitigating the effects of fossil fuel use. On the other hand, nutrient pollution is accelerating eutrophication rates in rivers, lakes, and coastal waters. Harvesting aquatic plants...
Plants, Vol. 9, Pages 422: Role and Regulation of Cytokinins in Plant Response to Drought Stress Plants doi: 10.3390/plants9040422 Authors: Nguyen Ngoc Hai Nguyen Nguyen Chuong Nguyen Huu Cam Tu Anna Kisiala Xuan Lan Thi Hoang Nguyen Phuong Thao Cytokinins (CKs) are key phytohormones that not only regulate plant growth and development but also mediate plant tolerance to drought stress. Recent advances in genome-wide association studies coupled with in planta characterization...
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Proteomes, Vol. 8, Pages 6: Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences Proteomes doi: 10.3390/proteomes8020006 Authors: Freitas Leal Lasonder Sharma Schiller Fanelli Rinalducci Brock Bosman Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion,...
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Religions, Vol. 11, Pages 161: Exploring Marginality among Filipino Catholics in Japan: A Proposed Heuristic Device Religions doi: 10.3390/rel11040161 Authors: Willard Enrique R. Macaraan The Church seeks to be inclusive; one that opens her doors to everyone. For many Filipino Catholics (FCs) in Japan, their ecclesial existence is marked by a history of negotiation as “guests” hosted by the Japanese Catholics (JCs). Within this field of host–guest interplay,...
Religions, Vol. 11, Pages 160: Disruptive Garb: Gender Production and Millennial Sikh Fashion Enterprises in Canada Religions doi: 10.3390/rel11040160 Authors: Zabeen Khamisa Several North American Sikh millennials are creating online values-based fashion enterprises that seek to encourage creative expression, self-determined representation, gender equality, and ethical purchasing, while steeped in the free market economy. Exploring the innovative ways young Sikhs of the diaspora express...
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Safety, Vol. 6, Pages 18: Improved Strategies for the Maritime Industry to Target Vessels for Inspection and to Select Inspection Priority Areas Safety doi: 10.3390/safety6020018 Authors: Sabine Knapp Christiaan Heij Inspection authorities such as the Port State Control Memoranda of Understanding use different policies and targeting methods to select vessels for inspections and rely primarily on past inspection outcomes. One of the main goals of inspections is to improve the safety...
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