Τρίτη 31 Μαρτίου 2020


Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study.
Related ArticlesUpper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study. Anesthesiology. 2019 11;131(5):962-973 Authors: Lodenius Å, Maddison KJ, Lawther BK, Scheinin M, Eriksson LI, Eastwood PR, Hillman DR, Fagerlund MJ, Walsh JH Abstract BACKGROUND: Dexmedetomidine is a sedative promoted as having minimal impact on ventilatory drive or upper airway muscle activity. However,...
pubmed: sleep
19h
Personalized goal for insomnia and clinical response in advanced cancer patients.
Related ArticlesPersonalized goal for insomnia and clinical response in advanced cancer patients. Support Care Cancer. 2020 Mar;28(3):1089-1096 Authors: Mercadante S, Adile C, Aielli F, Gaetano L, Mistakidou K, Maltoni M, Cortegiani A, Soares LG, De Santis S, Ferrera P, Rosati M, Rossi R, Casuccio A Abstract AIM: The aim of this study was to assess the Personalized Insomnia Intensity Goal (PIIG), the achievement of Personalized Goal Response (PGR),...
pubmed: sleep
19h
Neurocognitive performance under combined regimens of ketamine-dexmedetomidine and ketamine-fentanyl in healthy adults: A randomised trial.
Related ArticlesNeurocognitive performance under combined regimens of ketamine-dexmedetomidine and ketamine-fentanyl in healthy adults: A randomised trial. Prog Neuropsychopharmacol Biol Psychiatry. 2019 08 30;94:109647 Authors: Hayley AC, Green M, Downey LA, Keane M, Kenneally M, Adams M, Shehabi Y Abstract Analgesic doses of ketamine affects neurocognition; however, deficits under co-administration regimens are unknown. This study evaluated the effects...
pubmed: sleep
19h
Spatiotemporal distribution of individuals as an indicator for the social system of Lepilemur sahamalaza.
Related ArticlesSpatiotemporal distribution of individuals as an indicator for the social system of Lepilemur sahamalaza. Am J Primatol. 2019 07;81(6):e22984 Authors: Mandl I, Holderied M, Schwitzer C Abstract Primate social systems are highly diverse, complicating the classification of particularly elusive species that are difficult to observe. The spatial distribution of individuals over time is a critica lindicator for the social organization and...
pubmed: sleep
19h
H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls.
Related ArticlesH1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls. J Neuroimmunol. 2019 07 15;332:167-175 Authors: Schinkelshoek MS, Fronczek R, Kooy-Winkelaar EMC, Petersen J, Reid HH, van der Heide A, Drijfhout JW, Rossjohn J, Lammers GJ, Koning F Abstract Following the 2009 H1N1 influenza pandemic, an increased risk of narcolepsy type 1 was observed. Homology between...
pubmed: sleep
19h
Snore-GANs: Improving Automatic Snore Sound Classification With Synthesized Data.
Related ArticlesSnore-GANs: Improving Automatic Snore Sound Classification With Synthesized Data. IEEE J Biomed Health Inform. 2020 01;24(1):300-310 Authors: Zhang Z, Han J, Qian K, Janott C, Guo Y, Schuller B Abstract One of the frontier issues that severely hamper the development of automatic snore sound classification (ASSC) associates to the lack of sufficient supervised training data. To cope with this problem, we propose a novel data augmentation...
pubmed: sleep
19h
The effect of the standard length of the first prescription on the adherence to sublingual immunotherapy for patients with allergic rhinitis.
Related ArticlesThe effect of the standard length of the first prescription on the adherence to sublingual immunotherapy for patients with allergic rhinitis. Int Forum Allergy Rhinol. 2020 Mar 29;: Authors: Jin M, Zhang L, Zhou G, Zhang S, Li X, Hu S Abstract BACKGROUND: Poor adherence to sublingual immunotherapy (SLIT) has become a major cause of unsatisfactory clinical efficacy for patients with allergic rhinitis (AR). This study was designed to...
AA pubmed: head and neck
19h
Potential association between oral mucosal nevus and melanoma: a preliminary clinicopathologic study.
Related ArticlesPotential association between oral mucosal nevus and melanoma: a preliminary clinicopathologic study. Oral Dis. 2020 Mar 28;: Authors: Liu W, Wang Y, Du G, Zhou Z, Yang X, Shi L Abstract OBJECTIVES: To assess potential association between oral nevi (ON) and nevus-associated melanoma (NAM), in which melanoma cells coexist with nevus cells. METHODS: A total of 74 ON patients and 7 NAM patients were retrospectively reviewed....
AA pubmed: head and neck
19h
Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model.
Related ArticlesTargeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model. Photochem Photobiol. 2020 Mar 29;: Authors: Peng W, de Bruijn HS, Ten Hagen TLM, van Dam GM, Roodenburg JLN, Berg K, Witjes MJH, Robinson DJ Abstract Targeted photodynamic therapy (PDT) in head/neck cancer patients with a...
AA pubmed: head and neck
19h
Otorhinolaryngological dysfunctions induced by chronic kidney disease in pre- and post-transplant stages.
Related ArticlesOtorhinolaryngological dysfunctions induced by chronic kidney disease in pre- and post-transplant stages. Eur Arch Otorhinolaryngol. 2020 Mar 28;: Authors: Krajewska Wojciechowska J, Krajewski W, Zatoński T Abstract PURPOSE: Otorhinolaryngological abnormalities are common complications of chronic kidney disease (CKD) and its treatment. The main aim of this study was to provide a brief and precise review of the current knowledge regarding...
AA pubmed: head and neck
19h
Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice.
Related ArticlesPtaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice. Food Funct. 2020 Mar 29;: Authors: Gil da Costa RM, Neto T, Estêvão D, Moutinho M, Félix A, Medeiros R, Lopes C, Bastos MMSM, Oliveira PA Abstract Bracken (Pteridium spp.) is a common weed that is consumed as food especially in Asia, and is suspected of promoting carcinogenesis induced by papillomaviruses in the digestive...
AA pubmed: head and neck
19h
A potential post-removal pH neutralization strategy to mitigate nasal button battery injuries.
Related ArticlesA potential post-removal pH neutralization strategy to mitigate nasal button battery injuries. Int J Pediatr Otorhinolaryngol. 2020 Mar 17;133:110011 Authors: Sancaktar ME, Bakırtaş M Abstract OBJECTIVE: Button batteries (BBs) impacted in the nose of children can cause septal perforation, synechia, atrophy, necrosis and deformities such as saddle nose. Developing mitigation strategies that can reduce tissue damage after BB removal...
AA pubmed: head and neck
19h
Management of massive venous malformations by percutaneous injection of bleomycin combined with fibrin glue in the head and neck.
Related ArticlesManagement of massive venous malformations by percutaneous injection of bleomycin combined with fibrin glue in the head and neck. J Craniomaxillofac Surg. 2020 Mar 05;: Authors: Chu H, Xu F, Xu X Abstract PURPOSE: The aim of this study was to evaluate the effectiveness of percutaneous injection of bleomycin combined with fibrin glue in treating massive venous malformations (MVMs) in the head and neck region. MATERIALS AND...
AA pubmed: head and neck
19h
Postoperative risk stratification in oral squamous cell carcinoma.
Related ArticlesPostoperative risk stratification in oral squamous cell carcinoma. Br J Oral Maxillofac Surg. 2020 Mar 25;: Authors: McMahon JD, Pitts R, Isbister J, Aslam-Pervez B, James A, McLellan D, Wright S, Wales CJ, McCaul J, Thomson E, Ansell MJ, Hislop WS, MacIver C, Devine JC, Carson E Abstract Postoperative prognostic stratification using the Union for International Cancer Control (UICC) TNM 8th edition staging rules (UICC 8) may identify...
AA pubmed: head and neck
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Head and Neck Cancer Awareness Month.
Related ArticlesHead and Neck Cancer Awareness Month. J Am Dent Assoc. 2020 Apr;151(4):223-224 Authors: Carlson ER, Kademani D PMID: 32222170 [PubMed - in process]
AA pubmed: head and neck
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Differential Expression of TFF1 and TFF3 in Patients Suffering from Chronic Rhinosinusitis with Nasal Polyposis.
Related ArticlesDifferential Expression of TFF1 and TFF3 in Patients Suffering from Chronic Rhinosinusitis with Nasal Polyposis. Int J Mol Sci. 2019 Nov 01;20(21): Authors: Mihalj M, Bujak M, Butković J, Zubčić Ž, Tolušić Levak M, Čes J, Kopić V, Baus Lončar M, Mihalj H Abstract Trefoil family factor (TFF) proteins contribute to antimicrobial defense and the maintenance of sinonasal epithelial barrier integrity. Dysregulation of TFF expression may be...
AA pubmed: head and neck
19h
Cordycepin Enhances Radiosensitivity in Oral Squamous Carcinoma Cells by Inducing Autophagy and Apoptosis Through Cell Cycle Arrest.
Related ArticlesCordycepin Enhances Radiosensitivity in Oral Squamous Carcinoma Cells by Inducing Autophagy and Apoptosis Through Cell Cycle Arrest. Int J Mol Sci. 2019 Oct 28;20(21): Authors: Ho SY, Wu WS, Lin LC, Wu YH, Chiu HW, Yeh YL, Huang BM, Wang YJ Abstract Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide and accounts for over 90% of malignant neoplasms of the oral cavity, with a 5-year survival rate of less than...
AA pubmed: head and neck
19h
Use of a Foley catheter in the drainage of deep space neck infections.
Related ArticlesUse of a Foley catheter in the drainage of deep space neck infections. Br J Oral Maxillofac Surg. 2019 11;57(9):942-943 Authors: Hawkins A, Ponnusamy S, Markiewicz MR, Callahan N PMID: 31405602 [PubMed - indexed for MEDLINE]
AA pubmed: head and neck
19h
Metronidazole-induced encephalopathy caused by hyperbaric oxygen therapy in a patient with mandibular osteomyelitis.
Related ArticlesMetronidazole-induced encephalopathy caused by hyperbaric oxygen therapy in a patient with mandibular osteomyelitis. J Infect Chemother. 2019 Dec;25(12):1057-1059 Authors: Yamamoto Y, Asai N, Furuhashi A, Ono T, Yamagishi Y, Mikamo H, Kazaoka Y Abstract Metronidazole (MNZ) is prescribed for the treatment of infection caused by anaerobic bacteria and protozoa. Metronidazole-induced encephalopathy (MIE) has been known to be a side-effect,...
AA pubmed: head and neck
19h
Imaging Spectrum of Cavernous Sinus Lesions with Histopathologic Correlation.
Related ArticlesImaging Spectrum of Cavernous Sinus Lesions with Histopathologic Correlation. Radiographics. 2019 May-Jun;39(3):795-819 Authors: Mahalingam HV, Mani SE, Patel B, Prabhu K, Alexander M, Fatterpekar GM, Chacko G Abstract Cavernous sinuses are paired interconnected venous plexuses situated in the floor of the middle cranial fossa on either side of the sella turcica and sphenoid sinus. They are lined by dura mater and consist of multiple...
AA pubmed: head and neck
19h
Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma.
Related ArticlesIncreased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma. Cell Death Dis. 2019 01 17;10(2):41 Authors: Yang Y, Chen D, Liu H, Yang K Abstract Recent studies showed that lncRNA CASC9 was upregulated and acted as an oncogene in a variety of tumors. However, the expression and biological functions of CASC9 in oral squamous cell...
AA pubmed: head and neck
19h
Three-Dimensional Tumor Margin Demarcation Using the Hybrid Tracer Indocyanine Green-99mTc-Nanocolloid: A Proof-of-Concept Study in Tongue Cancer Patients Scheduled for Sentinel Node Biopsy.
Related ArticlesThree-Dimensional Tumor Margin Demarcation Using the Hybrid Tracer Indocyanine Green-99mTc-Nanocolloid: A Proof-of-Concept Study in Tongue Cancer Patients Scheduled for Sentinel Node Biopsy. J Nucl Med. 2019 06;60(6):764-769 Authors: Meershoek P, van den Berg NS, Brouwer OR, Teertstra HJ, Lange CAH, Valdés-Olmos RA, van der Hiel B, Balm AJM, Klop WMC, van Leeuwen FWB Abstract For radical resection of squamous cell carcinoma of the oral...
AA pubmed: head and neck
19h
Membrane-tethered Notch1 exhibits oncogenic property via activation of EGFR-PI3K-AKT pathway in oral squamous cell carcinoma.
Related ArticlesMembrane-tethered Notch1 exhibits oncogenic property via activation of EGFR-PI3K-AKT pathway in oral squamous cell carcinoma. J Cell Physiol. 2019 05;234(5):5940-5952 Authors: Zheng Y, Wang Z, Xiong X, Zhong Y, Zhang W, Dong Y, Li J, Zhu Z, Zhang W, Wu H, Gu W, Wu Y, Wang X, Song X Abstract Notch proteins are highly conserved cell surface receptors which play essential roles in cellular differentiation, proliferation, and apoptotic events...
AA pubmed: head and neck
19h
Occurrence of Spontaneous Cortical Spreading Depression Is Increased by Blood Constituents and Impairs Neurological Recovery after Subdural Hematoma in Rats.
Related ArticlesOccurrence of Spontaneous Cortical Spreading Depression Is Increased by Blood Constituents and Impairs Neurological Recovery after Subdural Hematoma in Rats. J Neurotrauma. 2019 01 15;36(2):395-402 Authors: Krenzlin H, Jussen D, Plath M, Tretzel SJ, Krämer T, Kempski O, Alessandri B Abstract Acute subdural hemorrhage (ASDH) is common and associated with severe morbidity and mortality. To date, the role of spontaneous cortical spreading...
AA pubmed: head and neck
19h
Balneotherapy in the Treatment of Chronic Shoulder Pain: A Randomized Controlled Clinical Trial.
Related ArticlesBalneotherapy in the Treatment of Chronic Shoulder Pain: A Randomized Controlled Clinical Trial. Altern Ther Health Med. 2020 Jan;26(1):18-24 Authors: Özkuk K, Ateş Z Abstract Context: To date, the number of studies investigating the effects of balneotherapy (BT) on chronic shoulder pain is small. Objective: This study intended to investigate the effects of BT on pain, disability, and quality of life for patients with chronic...
pubmed: philosophy for medic...
19h
Infodemiology of Crohn's disease and Ulcerative colitis using Google Trends - an approach to investigate patient needs.
Related ArticlesInfodemiology of Crohn's disease and Ulcerative colitis using Google Trends - an approach to investigate patient needs. Z Gastroenterol. 2020 Mar;58(3):224-233 Authors: Keller R, Fusco S, Stange EF, Malek NP, Wehkamp J, Klag T Abstract INTRODUCTION:  Inflammatory bowel diseases (IBD) highly affect quality of life. The course of disease and success of treatment are variable. These factors result in a high number of psychiatric comorbidities...
pubmed: philosophy for medic...
19h
Development of a computer-aided design software for the quantitative evaluation of aesthetic damage.
Related ArticlesDevelopment of a computer-aided design software for the quantitative evaluation of aesthetic damage. PLoS One. 2019;14(12):e0226322 Authors: Sakaguti NM, Fernandes MM, Mazzilli LEN, Plana JAC, Bouchardet FCH, Nogueira de Oliveira R Abstract Concerns associated with the assessment of aesthetic damage or injury raise critical difficulties, such as the scarcity of methodology and standardization that may result in fundamental precepts...
pubmed: philosophy for medic...
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Early recovery after endoscopic totally extraperitoneal (TEP) hernia repair in athletes with inguinal disruption: A prospective cohort study.
Related ArticlesEarly recovery after endoscopic totally extraperitoneal (TEP) hernia repair in athletes with inguinal disruption: A prospective cohort study. PLoS One. 2019;14(12):e0226011 Authors: Brans E, Reininga IHF, Balink H, Munzebrock AVE, Bessem B, de Graaf JS Abstract BACKGROUND: Groin pain is a common problem in athletes which results in loss of playing time. Moreover, it can be for the cause of athletic career termination. A common cause...
pubmed: philosophy for medic...
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A regional look at ethics in healthcare.
Related ArticlesA regional look at ethics in healthcare. Afr J Prim Health Care Fam Med. 2019 Oct 09;11(1):e1-e2 Authors: Kleinsmidt A Abstract No abstract available.PMID: 31714128 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
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Long-term health-related quality of life of adult patients treated with extracorporeal membrane oxygenation (ECMO): An integrative review.
Related ArticlesLong-term health-related quality of life of adult patients treated with extracorporeal membrane oxygenation (ECMO): An integrative review. Heart Lung. 2019 Nov - Dec;48(6):538-552 Authors: Knudson KA, Gustafson CM, Sadler LS, Whittemore R, Redeker NS, Andrews LK, Mangi A, Funk M Abstract BACKGROUND: Extracorporeal membrane oxygenation (ECMO), a rescue treatment for patients with severe pulmonary and/or cardiac dysfunction, is increasingly...
pubmed: philosophy for medic...
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A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors.
Related ArticlesA multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors. Blood. 2019 12 12;134(24):2127-2138 Authors: Young G, Liesner R, Chang T, Sidonio R, Oldenburg J, Jiménez-Yuste V, Mahlangu J, Kruse-Jarres R, Wang M, Uguen M, Doral MY, Wright LY, Schmitt C, Levy GG, Shima M, Mancuso ME Abstract Emicizumab, a bispecific humanized monoclonal antibody, bridges activated factor IX (FIX) and...
pubmed: philosophy for medic...
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Lanadelumab Injection Treatment For The Prevention Of Hereditary Angioedema (HAE): Design, Development And Place In Therapy.
Related ArticlesLanadelumab Injection Treatment For The Prevention Of Hereditary Angioedema (HAE): Design, Development And Place In Therapy. Drug Des Devel Ther. 2019;13:3635-3646 Authors: Bova M, Valerieva A, Wu MA, Senter R, Perego F Abstract Despite the efficacy of the on-demand treatment for the control of acute attacks of Hereditary Angioedema due to C1-Inhibitor Deficiency (C1-INH-HAE), the number and severity of attacks and the impairment in...
pubmed: philosophy for medic...
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Conflictos de intereses en medicina. Recomendaciones del CETREMI.
Related ArticlesConflictos de intereses en medicina. Recomendaciones del CETREMI. Gac Med Mex. 2019;155(5):563-564 Authors: Celis MÁ, Halabe J, Arrieta O, Burgos R, Campillo C, De la Llata M, Domínguez J, Islas S, Jasso L, Lifshitz A, Moreno M, Plancarte R, Reyes-Sánchez A, Ruiz-Argüelles GJ, Soda A, Verástegui E, Sotelo J Abstract Conflicts of interest are situations in which judgment and integrity of medical decisions or actions are influenced by a...
pubmed: philosophy for medic...
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Clinical Response to Personalized Exercise Therapy in Heart Failure Patients with Reduced Ejection Fraction is Accompanied by Skeletal Muscle Histological Alterations.
Related ArticlesClinical Response to Personalized Exercise Therapy in Heart Failure Patients with Reduced Ejection Fraction is Accompanied by Skeletal Muscle Histological Alterations. Int J Mol Sci. 2019 Nov 05;20(21): Authors: Lelyavina TA, Galenko VL, Ivanova OA, Komarova MY, Ignatieva EV, Bortsova MA, Yukina GY, Khromova NV, Sitnikova MY, Kostareva AA, Sergushichev A, Dmitrieva RI Abstract Abstract: Heart failure (HF) is associated with skeletal...
pubmed: philosophy for medic...
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Approach to the Assessment and Management of Pediatric Patients With Atopic Dermatitis: A Consensus Document. Section I: Overview of Pediatric Atopic Dermatitis.
Related ArticlesApproach to the Assessment and Management of Pediatric Patients With Atopic Dermatitis: A Consensus Document. Section I: Overview of Pediatric Atopic Dermatitis. J Cutan Med Surg. 2019 Nov/Dec;23(5_suppl):3S-11S Authors: Lara-Corrales I, Bergman JN, Landells I, Ramien ML, Lansang P Abstract Pediatric atopic dermatitis (AD) is one of the most common dermatoses encountered by health-care providers treating children. Diagnosis of AD is...
pubmed: philosophy for medic...
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Exploring the relationship between medical student basic psychological need satisfaction, resilience, and well-being: a quantitative study.
Related ArticlesExploring the relationship between medical student basic psychological need satisfaction, resilience, and well-being: a quantitative study. BMC Med Educ. 2019 Nov 05;19(1):405 Authors: Neufeld A, Malin G Abstract BACKGROUND: There is increasing acknowledgment that medical training is stressful for students and can impact their well-being. An important aspect of this is self-determination and basic psychological need satisfaction. A...
pubmed: philosophy for medic...
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Reanalysis of the physical and mental health summary scores of dialysis versus conservative care in older patients with advanced chronic kidney disease: a critical appraisal.
Related ArticlesReanalysis of the physical and mental health summary scores of dialysis versus conservative care in older patients with advanced chronic kidney disease: a critical appraisal. BMC Res Notes. 2019 Nov 04;12(1):722 Authors: Verberne WR, Dijkers J, Kelder JC, Jellema WT, van Delden JJM, Bos WJW Abstract OBJECTIVE: Non-dialytic conservative care is argued to be a reasonable treatment alternative for dialysis in selected older patients with...
pubmed: philosophy for medic...
19h
Benefits of a Food Supplement Containing Boswellia serrata and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study.
Related ArticlesBenefits of a Food Supplement Containing Boswellia serrata and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. J Altern Complement Med. 2020 Feb;26(2):123-129 Authors: Italiano G, Raimondo M, Giannetti G, Gargiulo A Abstract Background: Osteoarthritis (OA) is a joint disease involving articular cartilage degeneration causing patients pain, joint stiffness, physical disability, and significantly...
pubmed: philosophy for medic...
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Adverse reproductive health outcomes in a cohort of young women with breast cancer exposed to systemic treatments.
Related ArticlesAdverse reproductive health outcomes in a cohort of young women with breast cancer exposed to systemic treatments. J Ovarian Res. 2019 Oct 31;12(1):102 Authors: Silva C, Ribeiro Rama AC, Reis Soares S, Moura-Ramos M, Almeida-Santos T Abstract BACKGROUND: Breast cancer is the most common cancer in young women. Fortunately current survival rates of BC are significant which makes future fertility very important for quality of life of BC...
pubmed: philosophy for medic...
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