Nutrients, Vol. 12, Pages 1204: The Impact of Aerobic Exercise and Badminton on HDL Cholesterol Levels in Taiwanese Adults Nutrients doi: 10.3390/nu12051204 Authors: Yasser Nassef Kuan-Jung Lee Oswald Ndi Nfor Disline Manli Tantoh Ming-Chih Chou Yung-Po Liaw Elevated levels of high-density lipoprotein cholesterol (HDL-C) have been associated with a decreased risk of coronary heart disease (CHD). An active lifestyle is necessary to improve HDL-C, including (but not limited...
Sat Apr 25, 2020 03:00
Nutrients, Vol. 12, Pages 1205: Anti-Fatigue Effect of Prunus Mume Vinegar in High-Intensity Exercised Rats Nutrients doi: 10.3390/nu12051205 Authors: Jeong-Ho Kim Hyun-Dong Cho Yeong-Seon Won Seong-Min Hong Kwang-Deog Moon Kwon-Il Seo Nowadays, new types of vinegar have been developed using various raw materials and biotechnological processes. The fruit of Prunus mume has been extensively distributed in East Asia and used as a folk medication for fatigue. In this study,...
Sat Apr 25, 2020 03:00
Nutrients, Vol. 12, Pages 1200: Food Involvement, Eating Restrictions and Dietary Patterns in Polish Adults: Expected Effects of Their Relationships (LifeStyle Study) Nutrients doi: 10.3390/nu12041200 Authors: Marzena Jezewska-Zychowicz Jerzy Gębski Milena Kobylińska Understanding the factors that coexist with healthy and unhealthy eating behaviors is prevalent and important for public health. The aim of this study was to investigate the associations between food involvement, eating...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1193: A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis Nutrients doi: 10.3390/nu12041193 Authors: Liang Chen Chun Hu Molly Hood Xue Zhang Lu Zhang Juntao Kan Jun Du Novel coronaviruses (CoV) have emerged periodically around the world in recent years. The recurrent spreading of CoVs imposes...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1197: Better Dietary Knowledge and Socioeconomic Status (SES), Better Body Mass Index? Evidence from China—An Unconditional Quantile Regression Approach Nutrients doi: 10.3390/nu12041197 Authors: Jie Yu Xiao Han Hongxing Wen Jinzheng Ren Lihong Qi Obesity is a rapidly growing public health threat in China. Improvement of dietary knowledge may potentially reduce the risk of obesity and being overweight. However, existing studies focus on measuring...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1199: Microbial Adaptation Due to Gastric Bypass Surgery: The Nutritional Impact Nutrients doi: 10.3390/nu12041199 Authors: Silke Crommen Alma Mattes Marie-Christine Simon Bariatric surgery leads to sustained weight loss and the resolution of obesity-related comorbidities. Recent studies have suggested that changes in gut microbiota are associated with the weight loss induced by bariatric surgery. Several studies have observed major changes in the microbial...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1202: Monobutyrin and Monovalerin Affect Brain Short-Chain Fatty Acid Profiles and Tight-Junction Protein Expression in ApoE-Knockout Rats Fed High-Fat Diets Nutrients doi: 10.3390/nu12041202 Authors: Thao Duy Nguyen Frida Fåk Hållenius Xue Lin Margareta Nyman Olena Prykhodko Monobutyrin (MB) and monovalerin (MV), esters of short-chain fatty acids (SCFAs), have previously been shown to reduce liver cholesterol and inflammation in conventional rats...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1201: Plasma Adipokines Profile in Prepubertal Children with a History of Prematurity or Extrauterine Growth Restriction Nutrients doi: 10.3390/nu12041201 Authors: María Dolores Ordóñez-Díaz Mercedes Gil-Campos Katherine Flores-Rojas María Carmen Muñoz-Villanueva Concepción María Aguilera-García María Jose de la Torre-Aguilar Juan Luis Pérez-Navero Adipose tissue programming could be developed in very preterm infants with extrauterine growth...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1196: Proinflammatory Dietary Intake is Associated with Increased Risk of Metabolic Syndrome and Its Components: Results from the Population-Based Prospective Study Nutrients doi: 10.3390/nu12041196 Authors: Imran Khan Minji Kwon Nitin Shivappa James R. Hébert Mi Kyung Kim Metabolic syndrome (MetS) is a major public health challenge throughout the world, although studies on its association with the inflammatory potential of diet are inconsistent....
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1203: Social-Psychological Factors in Food Consumption of Rural Residents: The Role of Perceived Need and Habit within the Theory of Planned Behavior Nutrients doi: 10.3390/nu12041203 Authors: Jiaqi Huang Gerrit Antonides Fengying Nie To address the problem of malnutrition in poor rural areas of China, this study aims to examine the effects of social-psychological factors in food consumption of rural residents in poor counties of Southwest China. In addition,...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1195: Does ENaC Work as Sodium Taste Receptor in Humans? Nutrients doi: 10.3390/nu12041195 Authors: Albertino Bigiani Taste reception is fundamental for the proper selection of food and beverages. Among the several chemicals recognized by the human taste system, sodium ions (Na+) are of particular relevance. Na+ represents the main extracellular cation and is a key factor in many physiological processes. Na+ elicits a specific sensation, called salty taste,...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1194: Mechanisms of Lifespan Regulation by Calorie Restriction and Intermittent Fasting in Model Organisms Nutrients doi: 10.3390/nu12041194 Authors: Hwangbo Lee Abozaid Min Genetic and pharmacological interventions have successfully extended healthspan and lifespan in animals, but their genetic interventions are not appropriate options for human applications and pharmacological intervention needs more solid clinical evidence. Consequently, dietary...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1198: Kokumi Taste Active Peptides Modulate Salt and Umami Taste Nutrients doi: 10.3390/nu12041198 Authors: Mee-Ra Rhyu Ah-Young Song Eun-Young Kim Hee-Jin Son Yiseul Kim Shobha Mummalaneni Jie Qian John R. Grider Vijay Lyall Kokumi taste substances exemplified by g-glutamyl peptides and Maillard Peptides modulate salt and umami tastes. However, the underlying mechanism for their action has not been delineated. Here, we investigated the...
Fri Apr 24, 2020 03:00
Nutrients, Vol. 12, Pages 1187: Spirulina Enhances Bone Modeling in Growing Male Rats by Regulating Growth-Related Hormones Nutrients doi: 10.3390/nu12041187 Authors: Jin Ah Cho Seong Yeon Baek Sun Hee Cheong Mee Ree Kim In recent years, growth hormone deficiency in children has been treated with hormone therapy despite the possible significant side effects. Therefore, it was deemed beneficial to develop functional foods or dietary supplements for safely improving children’s...
Fri Apr 24, 2020 03:00
Pathogens, Vol. 9, Pages 324: Emergence of Drift Variants That May Affect COVID-19 Vaccine Development and Antibody Treatment Pathogens doi: 10.3390/pathogens9050324 Authors: Koyama Weeraratne Snowdon Parida New coronavirus (SARS-CoV-2) treatments and vaccines are under development to combat COVID-19. Several approaches are being used by scientists for investigation, including (1) various small molecule approaches targeting RNA polymerase, 3C-like protease, and RNA endonuclease;...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 323: Transcriptional Alteration of Gene Biomarkers in Hemocytes of Wild Ostrea edulis with Molecular Evidence of Infections with Bonamia spp. and/or Marteilia refringens Parasites Pathogens doi: 10.3390/pathogens9050323 Authors: Cocci Roncarati Capriotti Mosconi Palermo The European flat Ostrea edulis is highly susceptible to intracellular parasitic infections, particularly bonamiosis and marteiliosis. The defensive response of oyster to both...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 325: Ecology of Neglected Rodent-Borne American Orthohantaviruses Pathogens doi: 10.3390/pathogens9050325 Authors: Mull Jackson Sironen Forbes The number of documented American orthohantaviruses has increased significantly over recent decades, but most fundamental research has remained focused on just two of them: Andes virus (ANDV) and Sin Nombre virus (SNV). The majority of American orthohantaviruses are known to cause disease in humans, and most...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 320: Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs Pathogens doi: 10.3390/pathogens9050320 Authors: Neogi Hill Ambikan Heng Quinn Byrareddy Sönnerborg Sarafianos Singh Coronaviruses (CoVs) are positive-stranded RNA viruses that infect humans and animals. Infection by CoVs such as HCoV-229E, -NL63, -OC43 and -HKU1 leads to the common cold, short lasting rhinitis, cough, sore throat and fever. However,...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 321: Encystment Induces Down-Regulation of an Acetyltransferase-Like Gene in Acanthamoeba castellanii Pathogens doi: 10.3390/pathogens9050321 Authors: Rolland Mengue Noël Crapart Mercier Aucher Héchard Samba-Louaka Acanthamoeba castellanii is a ubiquitous free-living amoeba. Pathogenic strains are causative agents of Acanthamoeba keratitis and granulomatous amoebic encephalitis. In response to adverse conditions, A. castellanii differentiate...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 322: Mutation of the Carboxy-Terminal Processing Protease in Acinetobacter baumannii Affects Motility, Leads to Loss of Membrane Integrity, and Reduces Virulence Pathogens doi: 10.3390/pathogens9050322 Authors: Rakesh Roy Ren-In You Ming-Der Lin Nien-Tsung Lin Motility plays an essential role in the host–parasite relationship of pathogenic bacteria, and is often associated with virulence. While many pathogenic bacteria use flagella for locomotion,...
Sun Apr 26, 2020 03:00
Pathogens, Vol. 9, Pages 318: Escherichia coli Strains with Virulent Factors Typical for Uropathogens were Isolated from Sinuses from Patients with Chronic Rhinosinusitis—Case Report Pathogens doi: 10.3390/pathogens9050318 Authors: Beata Krawczyk Michał Michalik Magdalena Fordon Magdalena Wysocka Alfred Samet Bogdan Nowicki Escherichia coli were isolated from three patients with chronic rhinosinusitis (CRS) by intraoperative sinus tissue biopsy. Taking into account the...
Sat Apr 25, 2020 03:00
Pathogens, Vol. 9, Pages 319: Paenibacillus alvei MP1 as a Producer of the Proteinaceous Compound with Activity against Important Human Pathogens, Including Staphylococcus aureus and Listeria monocytogenes Pathogens doi: 10.3390/pathogens9050319 Authors: Magdalena Pajor Zirui Ray Xiong Randy W. Worobo Piotr Szweda An emerging need for new classes of antibiotics is, on the one hand, evident as antimicrobial resistance continues to rise. On the other hand, the awareness of the...
Sat Apr 25, 2020 03:00
Pathogens, Vol. 9, Pages 317: Catalase and Ascorbate Peroxidase in Euglenozoan Protists Pathogens doi: 10.3390/pathogens9040317 Authors: Ingrid Škodová-Sveráková Kristína Záhonová Barbora Bučková Zoltán Füssy Vyacheslav Yurchenko Julius Lukeš In this work, we studied the biochemical properties and evolutionary histories of catalase (CAT) and ascorbate peroxidase (APX), two central enzymes of reactive oxygen species detoxification, across the highly diverse clade Eugenozoa....
Fri Apr 24, 2020 03:00
Pathogens, Vol. 9, Pages 315: The Role of the Maridi Dam in Causing an Onchocerciasis-Associated Epilepsy Epidemic in Maridi, South Sudan: An Epidemiological, Sociological, and Entomological Study Pathogens doi: 10.3390/pathogens9040315 Authors: T.L. Lakwo S. Raimon M. Tionga J.N. Siewe Fodjo P. Alinda W.J. Sebit J.Y. Carter R. Colebunders Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis‐endemicvillages close to the Maridi River in South...
Fri Apr 24, 2020 03:00
Pathogens, Vol. 9, Pages 314: Salmonella Typhimurium Triggered Unilateral Epididymo-Orchitis and Splenomegaly in a Holstein Bull in Assiut, Egypt: A Case Report Pathogens doi: 10.3390/pathogens9040314 Authors: Manal A. M. Mahmoud Gaber Megahed Mohamed S. Yousef Fatma Abo Zakaib Ali Rania S. Zaki Hanan H. Abdelhafeez This report illustrates, for the first time, a case of unilateral orchitis and epididymitis in a Holstein-Friesian bull, associated with Salmonella enterica...
Fri Apr 24, 2020 03:00
Pathogens, Vol. 9, Pages 316: Venereal Transmission of Vesicular Stomatitis Virus by Culicoides sonorensis Midges Pathogens doi: 10.3390/pathogens9040316 Authors: Paula Rozo-Lopez Berlin Londono-Renteria Barbara S. Drolet Culicoides sonorensis biting midges are well-known agricultural pests and transmission vectors of arboviruses such as vesicular stomatitis virus (VSV). The epidemiology of VSV is complex and encompasses a broad range of vertebrate hosts, multiple routes of transmission,...
Fri Apr 24, 2020 03:00
Pathogens, Vol. 9, Pages 313: Oral Microbiota: Discovering and Facing the New Associations with Systemic Diseases Pathogens doi: 10.3390/pathogens9040313 Authors: Romeo Patini The economic crisis of the first decades of the 2000s had serious repercussions on the economy of individual countries, producing a gradual impoverishment of populations. The reduction in financial resources has significantly reduced citizens’ access to care, forcing them to abandon preventive medicine...
Fri Apr 24, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 80: Paradoxical Anticonvulsant Effect of Cefepime in the Pentylenetetrazole Model of Seizures in Rats Pharmaceuticals doi: 10.3390/ph13050080 Authors: Dmitry V. Amakhin Ilya V. Smolensky Elena B. Soboleva Aleksey V. Zaitsev Many β-lactam antibiotics, including cephalosporins, may cause neurotoxic and proconvulsant effects. The main molecular mechanism of such effects is considered to be γ-aminobutyric acid type a (GABAa) receptor...
Sun Apr 26, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 79: Multitarget Activities of Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Against Alzheimer’s Disease Pharmaceuticals doi: 10.3390/ph13050079 Authors: Chantha Chheng Pornthip Waiwut Kusawadee Plekratoke Yaowared Chulikhit Supawadee Daodee Orawan Monthakantirat Supaporn Pitiporn Natdanai Musigavong Pakakrong Kwankhao Chantana Boonyarat The Kleeb Bua Daeng formula (KBD) is a Thai traditional medicine for brain health promotion....
Sat Apr 25, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 78: Methanolic Extract of the Herb Ononis spinosa L. Is an Antifungal Agent with no Cytotoxicity to Primary Human Cells Pharmaceuticals doi: 10.3390/ph13040078 Authors: Dejan Stojković Maria Inês Dias Danijela Drakulić Lillian Barros Milena Stevanović Isabel C. F. R. Ferreira Marina D. Soković Ononis spinosa L. is a plant traditionally used as folk remedy. There are numerous studies regarding chemical constituents and health beneficial...
Fri Apr 24, 2020 03:00
Pharmaceutics, Vol. 12, Pages 398: Development of Gel-in-Oil Emulsions for Khellin Topical Delivery Pharmaceutics doi: 10.3390/pharmaceutics12050398 Authors: Joana Pereira Rita Gonçalves Margarida Barreto Clarisse Dias Fátima Carvalho António J. Almeida Helena Margarida Ribeiro Joana Marto Hypopigmentation is a progressive dermatological condition caused by a reduction in the skin pigment, melanin. Its treatment is considered a challenge due to the lack of a highly...
Sun Apr 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 397: Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats Pharmaceutics doi: 10.3390/pharmaceutics12050397 Authors: Yoo-Kyung Song Jin-Ha Yoon Jong Kyu Woo Ju-Hee Kang Kyeong-Ryoon Lee Seung Hyun Oh Suk-Jae Chung Han-Joo Maeng The potential inhibitory effect of quercetin, a major plant flavonol, on breast cancer resistance protein (BCRP) activity was...
Sun Apr 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 396: Hydrogel-Based Active Substance Release Systems for Cosmetology and Dermatology Application: A Review Pharmaceutics doi: 10.3390/pharmaceutics12050396 Authors: Martyna Zagórska-Dziok Marcin Sobczak Hydrogels are playing an increasingly important role in medicine and pharmacy. Due to their favorable physicochemical properties, biocompatibility, and designed interaction with living surroundings, they seem to be one of the most promising groups of biomaterials....
Sun Apr 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 394: Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol M. tuberculosis Challenge in Rhesus Macaques Pharmaceutics doi: 10.3390/pharmaceutics12050394 Authors: Andrew D. White Charlotte Sarfas Laura S. Sibley Jennie Gullick Simon Clark Emma Rayner Fergus Gleeson Martí Català Isabel Nogueira Pere-Joan Cardona Cristina Vilaplana Mike J. Dennis Ann Williams Sally A. Sharpe Ten million cases of...
Sat Apr 25, 2020 03:00
Pharmaceutics, Vol. 12, Pages 395: Is Antimicrobial Treatment Effective During Therapeutic Plasma Exchange? Investigating the Role of Possible Interactions Pharmaceutics doi: 10.3390/pharmaceutics12050395 Authors: Łukasz J. Krzych Marcelina Czok Zbigniew Putowski Antimicrobial treatment during therapeutic plasma exchange (TPE) remains a complex issue. Recommendations based on a limited number of experimental studies should be implemented in clinical practice with caution. Effective...
Sat Apr 25, 2020 03:00
Pharmaceutics, Vol. 12, Pages 393: The Role of Functional Excipients in Solid Oral Dosage Forms to Overcome Poor Drug Dissolution and Bioavailability Pharmaceutics doi: 10.3390/pharmaceutics12050393 Authors: Jannes van der Merwe Jan Steenekamp Dewald Steyn Josias Hamman Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these...
Sat Apr 25, 2020 03:00
Pharmaceutics, Vol. 12, Pages 391: HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution Pharmaceutics doi: 10.3390/pharmaceutics12040391 Authors: Haozhong Ding Mohamed Altai Wen Yin Sarah Lindbo Hao Liu Javad Garousi Tianqi Xu Anna Orlova Vladimir Tolmachev Sophia Hober Torbjörn Gräslund The human epidermal growth factor receptor 2 (HER2) is a clinically validated...
Fri Apr 24, 2020 03:00
Pharmaceutics, Vol. 12, Pages 392: Ionic Liquid-in-Oil Microemulsions Prepared with Biocompatible Choline Carboxylic Acids for Improving the Transdermal Delivery of a Sparingly Soluble Drug Pharmaceutics doi: 10.3390/pharmaceutics12040392 Authors: Md. Rafiqul Islam Md. Raihan Chowdhury Rie Wakabayashi Noriho Kamiya Muhammad Moniruzzaman Masahiro Goto The transdermal delivery of sparingly soluble drugs is challenging due to of the need for a drug carrier. In the past few...
Fri Apr 24, 2020 03:00
Pharmaceutics, Vol. 12, Pages 388: Investigating the Effect of Encapsulation Processing Parameters on the Viability of Therapeutic Viruses in Electrospraying Pharmaceutics doi: 10.3390/pharmaceutics12040388 Authors: Tayo Sanders Anita Milicic Eleanor Stride The ability of viruses to introduce genetic material into cells can be usefully exploited in a variety of therapies and also vaccination. Encapsulating viruses to limit inactivation by the immune system before reaching the desired...
Fri Apr 24, 2020 03:00
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