Abstract The purpose of this study was to assess the interrater and test-retest reliability and the concurrent validity of the modified timed up and go test for preschoolers. As such, we aim to determine the most suited outcome of the modified timed up and go test: the best or the average performance. Thirty-two children (age 3–5) performed three timed up and go test trials as fast as possible on two separate occasions. During the first session, two researchers recorded the time...
Successful Liposteroid Therapy for a Recurrent Idiopathic Pulmonary Hemosiderosis with Down Syndrome
Idiopathic pulmonary hemosiderosis (IPH) is a rare and life-threatening disorder. Early diagnosis and appropriate management are essential for their better prognosis and patients’ quality of life (QOL). It is considered that Down syndrome patients with IPH have a worse prognosis compared to other IPH cases. A 2-year-old girl with Down syndrome received the diagnosis of IPH after two episodes of massive pulmonary hemorrhage requiring assist ventilation, who suffered from recurrent IPH during tapering...
The need for an efficient power source for operating the modern industry has been rapidly increasing in the past years. Therefore, the latest renewable power sources are difficult to be predicted. The generated power is highly dependent on fluctuated factors (such as wind bearing, pressure, wind speed, and humidity of surrounding atmosphere). Thus, accurate forecasting methods are of paramount importance to be developed and employed in practice. In this paper, a case study of a wind harvesting farm...
In the deep mining areas of western China, there exist ultrathick and weak cementation strata in the overburdens above the Jurassic coal seams, and the overburden lithology is generally moderately a little weaker than the medium-hard strata. Yet, the practical measurement indicates that the surface movement rule in this area displays the specialty that is apparently inconsistent with its lithology, which increases the uncertainty of safe production in coal mines. In this study, the similar material...
Background. Traditional Chinese Patent Medicine (TCPM) is now being used more and more extensively for primary hypertension in China. However, the comparative efficacy and safety of it need more clarified evidence. Thus, we conducted a Bayesian network meta-analysis to compare TCPMs with other interventions. Methods. We searched China National Knowledge Infrastructure (CNKI), WanFang Data, PubMed, Embase, and Cochrane Library from inception to April 2019 for randomized controlled trials (RCTs) with...
This study aims to explore the possible homologous mechanism of 7 frequently‐used herbs for heat-clearing and detoxification in traditional Chinese medicine (HDTCM) for treating Alzheimer's disease (AD), one of the most common types of dementia, based on network pharmacology. Herbs that satisfied the criteria of containing chlorogenic acid, relating to AD and aligning with HDTCM, were simultaneously collected to determine whether they have anti-AD effect based on a survey of the literature. Herb-ingredient-target-disease...
This present study evaluated the effects of processed P. multiflorum on osteogenesis using Sarcoma osteogenic (SaOS-2) cell lines and osteoclastogenesis of bone marrow-derived macrophage cells (BMM) and to elucidate differences in effect on the expression of bone-related proteins between commercially sold P. multiflorum and patented, in vitro-propagated Korea Institute of Oriental Medicine (KIOM) P. multiflorum. Raw P. multiflorum and P. multiflorum that were stir-baked and steamed in black bean...
While the urea cycle disorders (UCDs) classically present in the neonatal stage, they have become increasingly recognized as a rare cause of unexplained hyperammonemic encephalopathy in adults. Many metabolic triggers for late-onset UCDs have been described in the literature including excessive protein intake. In this case series, ten such documented cases are reviewed with analysis of patient demographic, protein load, treatment course, and patient outcome. Common delays in treatment include recognition...
Aim. To evaluate the clinical impact of β-blocker in patients with adequate left ventricular ejection function (LVEF) who underwent percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). Methods. A total of 10,724 consecutive patients who underwent PCI throughout 2013 were prospectively enrolled in the study. Among these, we analyzed 5,631 ACS patients who were discharged with . Patients were then compared according to the β-blocker prescription at discharge. Results. During...
In this paper, we develop a phenomenological model inspired by QCD that mimics the QCD theory. We use the gauge theory in color dielectric medium () coupled with fermion fields to produce scalar and vector confinements in the chromoelectric flux tube scenario. The Abelian theory will be used to approximate the non-Abelian QCD theory in a consistent manner. We will calculate vector and scalar glueballs and compare the result to the existing simulation and experimental results and projections. The...
The present study aimed to investigate the effect of microglia on simulated microgravity-induced hippocampal neurogenesis reduction and the possible mechanism underlying. Adult rats were treated with tail suspension for different times and the changes of neural stem cells (NSCs) were examined by immunohistochemistry. Then, minocycline was used to inhibit the activation of microglia, and the numbers of microglia and NSCs were detected after microgravity. Additionally, liquid protein chip analysis...
Xuefu Zhuyu Decoction (XFZYD), a Traditional Chinese Medicine (TCM) decoction mainly for treating blood stasis syndrome, has been widely investigated and applied in clinic and in laboratory. XFZYD contains 11 herbs and has been identified to promoting blood circulation to remove blood stasis for cardiovascular disease. Meanwhile, blood stasis is directly related to malignant tumor according to TCM basic theory. However, the effects of XFZYD on tumor metastasis and the underlying mechanisms are still...
Osteoarthritis (OA) is the most common chronic degenerative joint disease, and it remains the main cause of chronic disability in elderly individuals. Sema4D (semaphorin 4D) is involved in the immune system and related to bone injury, osteoporosis, osteoblast differentiation, and rheumatoid arthritis. However, the role of Sema4D in OA remains unclear. Hence, the LPS-stimulated chondrocyte cell injury model was constructed in this study to investigate the role of Sema4D in OA development. The results...
Objectives. The purpose of this study was to evaluate the evidence of art therapy on the psychological outcome, quality of life (QOL), and cancer-related symptoms in women with gynecological cancer. Methods. A systematic literature search was conducted. The randomized controlled trials, quasiexperimental studies, case reports, and qualitative studies were all included. Result. 1,587 articles were retrieved. A total of 9 articles met the inclusion criteria. The existing studies provided initial evidence...
Parkinson’s disease (PD) patients can benefit from antioxidant supplementation, and new efficient antioxidants are needed. The aim of this study was to evaluate the protective effect of selected nitroxide-containing redox nanoparticles (NRNPs) in a cellular model of PD. Antioxidant properties of NRNPs were studied in cell-free systems by protection of dihydrorhodamine 123 against oxidation by 3-morpholino-sydnonimine and protection of fluorescein against bleaching by 2,2-azobis(2-amidinopropane)...
Objective. To explore the role of the c-Jun N-terminal kinase (JNK) signaling pathway in upregulated NGAL expression and its antiapoptotic mechanism in lipopolysaccharide (LPS)-mediated renal tubular epithelial cell injury. Methods. In vitro, HK-2 cells were divided into five groups (Con, LPS 1 h, LPS 3 h, LPS 6 h, and LPS 12 h groups) based on the time of LPS (10 μM) treatment. NGAL and caspase-3 gene expression levels were detected by RT-PCR to assess dynamic changes. HK-2 cells were pretreated...
Lignocellulosic biomass can be used to obtain fermentable sugars by enzymatic hydrolysis, and also it serves as a carbon source to produce cellulases by solid-state fermentation. In this study, we propose the use of leaves of Agave salmiana as a carbon source to produce cellulases by the fungus Penicillium sp., isolated from the same plant. The crude enzymatic extract was used to obtain sugars from the hydrolysis of the parenchymal cells of the leaves. The enzymes produced were characterized (endoglucanase...
Mitochondrial fusion/mitophagy plays a role in cardiovascular calcification. Melatonin has been shown to protect against cardiovascular disease. This study sought to explore whether melatonin attenuates vascular calcification by regulating mitochondrial fusion/mitophagy via the AMP-activated protein kinase/optic atrophy 1 (AMPK/OPA1) signaling pathway. The effects of melatonin on vascular calcification were investigated in vascular smooth muscle cells (VSMCs). Calcium deposits were visualized by...
The aim of the study was to evaluate the effect of probiotics and herbal products on the intestinal histomorphological and immunological development in piglets. Accordingly, 2-week-old piglets were allocated in 4 groups: C (basal diet), Pro (basal diet + probiotics), Pro+B (basal diet + probiotics + buckwheat bran), and H (powder of herbs). After 6 weeks of the experiment, 4 piglets from each experimental group were randomly selected and slaughtered at a slaughterhouse. Samples of tissue and digestive...
In an immunocompetent host, excess infiltration of immune cells in the lung is a key factor in infection-induced severe acute lung injury. Kidney transplant patients are immunocompromised by the use of immunosuppressive drugs. Immune cell infiltration in the lung in a renal transplant recipient suffering from pulmonary infection is significantly less than that in an immunocompetent host; however, the extent of lung injury in renal transplant patients is more serious than that in immunocompetent hosts....
Background. Patients undergoing hemodialysis experience a greater risk of cognitive impairment than the general population, but limited data elucidates the biomarkers on this. We evaluated the association of bone turnover markers on cognitive function among 251 prevalent hemodialysis enrollees in a cross-sectional study. Methods. 251 hemodialysis patients (, 55% men) and 37 control subjects (, 56% men) without a prior stroke or dementia diagnosis were enrolled. Serum concentrations of 8 bone markers...
Brittleness and crack initiation stress (σci) are important rock mechanical properties and intrinsically related to rock deformation and failure. We establish the relationship between σci and uniaxial tensile strength (σt) based on the Griffith stress criterion of brittle failure and introduce brittleness indexes B1–B4 based on the ratio of uniaxial compressive strength (σc) to σt. The crack initiation stress ratio (K) is defined as the ratio of σci to crack damage stress. The relationship between...
LEDs are widely applied in highways and tunnels for their long life, low light attenuation, and being environment friendly in recent years. The influence of correlated color temperature (CCT) of LED on lighting safety has attracted people’s attention as the demand increased. In this paper, a calculation model of perception luminance of human eye considering mesopic vision and fog concentration was proposed. The influence of different CCTs on perception luminance of human eye under different levels...
Trihalomethanes (THMs) are formed when excess chlorine during chlorination of water reacts with organic material in water. They have mutagenic and carcinogenic properties. Moringa oleifera (MO) has found wide acceptance by many people in Nigeria who have used it for food for both humans and fauna, for health purposes, and as a coagulant for water treatment. However, the seed husks are currently discarded as waste and they have not been used as adsorbent to remove THMs from water. The physicochemical...
In wireless digital communications, amplitude-shift keying (ASK) and frequency-shift keying (FSK) modules are often used and radio frequency (RF), communication synchronization, and noise problems affect the performance very much. In particular, the sending of byte-type data called synchronous and preamble before sending data in intermodule communication increases the sent data and decreases the speed. Also, the microcontroller at the output of the RF receiver module continuously listens to the RF...
Objective. The aim of this study was to test whether Amflow® (a newly designed portable ventilation feedback device) can assist rescuers in delivering target tidal volume () and respiration rate (RR) during self-inflating bag (SB) ventilations in various clinical scenarios. Method. This was a simulation study with a prospective cross-over design. A total of 40 trained participants who underwent training for SB ventilation were recruited. Using a SB with or without Amflow® alternately, participants...
Diatoms exhibit high solar energy harvesting efficiency due to their remarkably organized, hierarchical micro/nanoporous, light-trapping, and scattering frustules. At present, few studies focus on cosensitization of natural near-infrared dye to expand the spectral response of dye-sensitized solar cells. In this study, the diatom frustule-TiO2 (12 : 5) composite film was prepared and assembled it on the TiO2 electrode. Compared to the single TiO2 layer film, diatom frustule-TiO2 (12 : 5) composite...
Estimation of solution norms and stability for time-dependent nonlinear systems is ubiquitous in numerous engineering, natural science, and control problems. Yet, practically valuable results are rare in this area. This paper develops a novel approach, which bounds the solution norms, derives the corresponding stability criteria, and estimates the trapping/stability regions for some nonautonomous and nonlinear systems, which arise in various application domains. Our inferences rest on deriving a...
Ferric oxide-amine material was synthesized and applied as a novel adsorbent for nitrate and phosphate removal from aqueous solution. The properties of ferric oxide-amine were examined using TGA, FTIR, BET, SEM, EDX, SEM-mapping, and XRD analysis. The results showed that the adsorption using ferric oxide-amine material reached equilibrium after 30 and 60 min for nitrate and phosphate, respectively. The highest nitrate and phosphate adsorption capacities were 131.4 mg nitrate/g at pH 5-6 and 42.1 mg...
We present a Bayesian approach for analysis of competing risks survival data with masked causes of failure. This approach is often used to assess the impact of covariates on the hazard functions when the failure time is exactly observed for some subjects but only known to lie in an interval of time for the remaining subjects. Such data, known as partly interval-censored data, usually result from periodic inspection in production engineering. In this study, Dirichlet and Gamma processes are assumed...
A single-nucleotide polymorphism causing a C to G change in the PNPLA3 gene (rs738409) is associated with disease severity and development of hepatocellular carcinoma (HCC) in nonalcoholic fatty liver disease; the insertion variant rs72613567:TA of the 17β-hydroxysteroid dehydrogenase type 13 (HSD17B13) mitigates this detrimental effect. Our aim was to evaluate if the same holds true in chronic hepatitis C virus infection (HCV). With a case control retrospective study design, we selected 110 patients...
Visceral leishmaniasis (VL), known as kala-azar, is a serious parasitic disease. After malaria, VL is the second largest parasitic killer. This paper focuses on the VL transmission around sandflies, dogs, and people. Kashgar is located on the southwestern edge of Xinjiang, where kala-azar parasite infection occurs every year. According to the cases reported in the Kashgar Prefecture from 2004 to 2016, we proposed a dynamic model based on these three populations. The SEIR model was established for...
This paper presents an output control for a manipulator by changing the spring stiffness. Through the modeling and analysis of the nonlinear stiffness characteristics of the crank-rocker mechanism, and using the zero stiffness domain search method to select the appropriate spring stiffness, using different spring stiffness to establish different mechanism models, the robot can finally control the output of ideal constant force, and at the same time, the analysis results are applied to the improved...
This paper concerns robust stabilization of nonlinear fractional order interconnected systems. Based on uncertain fractional order Takagi–Sugeno fuzzy model and the fractional order extension of lyapunov direct method, a parallel distributed compensate controller is designed to asymptotically stabilize the fractional order interconnected systems. Then, a sufficient condition is given in the format of linear matrix inequalities. Simulation example is given to validate the effectiveness of the approach.
Diabetes is one of the world’s major health problems, and many reports have supported the role of oxidative stress in the pathogenesis of both type 1 and type 2 diabetes. The present study aims to evaluate the antidiabetic and antioxidant activity of Bauhinia rufescens, a plant used in Sudanese folkloric medicine for the treatment of diabetes. It was also aimed to identify isolates and characterize the bioactive antidiabetic and antioxidant compounds using bioactivity-guided fractionation followed...
Objectives. To compare the efficacy and safety profiles of systemic glutathione as a skin-whitening agent in adults from several randomized controlled trials (RCTs). Methods. This study is an evidence-based case report with literature search conducted on Clinical Key, Cochrane, Journal of the American Academy of Dermatology, Taylor and Francis Online, ScienceDirect, and PubMed databases. Three relevant RCTs were extracted and assessed for validity, importance, and applicability. Results. From 3 included...
Innovation subsidy is of great significance to promoting enterprise innovation development. However, in recent years, the frequent occurrence of R&D subsidy deception in China has greatly reduced effectiveness of innovation. From the perspective of the strategic choice motivation of the innovation subject (including the enterprises, research institutions, and local governments), this paper constructs a multiplayer stochastic evolutionary game model. The influence of each variable on the subject...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου