A multimode process monitoring method based on multiblock projection nonnegative matrix factorization (MPNMF) is proposed for traditional process monitoring methods which often adopt global model of data and ignore local information of data. Firstly, the training data set of each mode is partitioned by the complete link algorithm and the multivariate data space is divided into several subblocks. Then, the projection nonnegative matrix factorization (PNMF) algorithm is used to model each subspace...
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In recent years, with the improvement of Internet of Things (IOT) technology, a “shared” service concept has appeared in people’s life. In the limited available resources, it is of great value to study the optimal path of charging pile selection for shared cars. With the help of Internet of Things technology and through analyzing the collected data, this paper introduces three path optimization methods, the Dijkstra algorithm, heuristic algorithm , and improved particle swarm optimization (PSO) algorithm;...
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Gallstone ileus is a dramatic complication of gallstone disease, uncommon but not exceptional in a busy emergency department. It represents a cause of mechanical intestinal obstruction, which predominantly occurs in elderly and frail patients; this contributes to the high morbidity and mortality rates associated with this condition. The modern radiologist is frequently asked to determine the cause of bowel obstruction and should be aware of the most pictorial features of this unusual disease. Broadly...
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Objective. In this study, the data mining method was used to screen the core Chinese materia medicas (CCMMs) against primary liver cancer (PLC), and the potential mechanisms of CCMMs in treating PLC were analyzed based on network pharmacology. Methods. Traditional Chinese medicine (TCM) prescriptions for treating PLC were obtained from a famous TCM doctor in Shenzhen, China. According to the data mining technique, the TCM Inheritance Support System (TCMISS) was applied to excavate the CCMMs in the...
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In the present study, a fluorescent sensor L for sensing of Ce3+ ion was designed and characterized by XRD, 1HNMR, and FTIR. Its fluorescence behavior towards metal ion was examined by fluorescence spectroscopy. Chelation-enhanced fluorescence was shown by the sensor L upon interaction with Ce3+ ion. This fluorescent sensor exhibits high sensitivity and selectivity towards Ce3+ ion in acetonitrile solution, forming 2 : 1 (L : M) complex as determined by Job’s plot. Association constant was found...
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Recently, different distributions have been generalized using the -R {Y} framework but the possibility of using Dagum distribution has not been assessed. The -R {Y} combines three distributions, with one as a baseline distribution, with the strength of each distribution combined to produce greater effect on the new generated distribution. The new generated distributions would have more parameters but would have high flexibility in handling bimodality in datasets and it is a weighted hazard function...
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Objectives. To investigate the risk factors for cognitive impairment in Chinese type 2 diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of mild cognitive impairment (MCI) in these patients. Methods. Chinese T2DM patients () aged 50–70 years were divided into groups with impaired (mild, moderate, and severe) and normal cognitive function based on Montreal Cognitive Assessment and Mini-Mental State Examination scores. Data regarding demographic characteristics,...
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The aim of this study was to compare the effects of preoperative intranasal dexmedetomidine and oral midazolam on preoperative sedation and postoperative agitation in pediatric dentistry. A total of 60 children (ASA grade I, aged 3–6 years) scheduled for elective pediatric dental treatment were randomly divided into the dexmedetomidine (DEX) and midazolam (MID) groups. Ramsay sedation score, parental separation anxiety scale, mask acceptance scale, pediatric anesthesia emergence delirium scale, and...
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Purpose. Metabolic syndrome (MetS) is associated with chronic stress. miR-18a-5p and miR-22-3p are two miRNAs which can target the glucocorticoid receptor. This study looked at the changes in metabolic parameters and the predictive value of the peripheral blood mononuclear cells (PBMCs) to stress-associated miRNA ratios as new indicators in subjects with and without MetS in southern China. Patients and Methods. There were 81 participants (39 with MetS and 42 without MetS) in this cross-sectional...
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The repair of bone defects is a big challenge in reconstructive surgery. Periosteal distraction osteogenesis (PDO), as a promising technique used for bone regeneration, forms a space between the periosteum and bone cortex to regenerate the new bone merely by distracting the periosteum. In order to investigate the influence of distractor framework on the PDO, we utilized three-dimensional (3D) printing technology to fabricate three kinds of poly-L-lactic acid (PLLA) scaffolds with different pore sizes...
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Chronic wounds represent serious globally health care and economic issues especially for patients with hyperglycemic condition. Wound dressings have a predominant function in wound treatment; however, the dressings for the long-lasting and non-healing wounds are still a significant challenge in the wound care management market. Astonishingly, advanced wound dressing which is embedded with a synthetic drug compound in a natural polymer compound that acts as drug release carrier has brought about promising...
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The mechanical response characteristics of rocks under cyclic loading conditions are crucial factors for evaluating and analyzing the stability of rock mass during underground excavation. In this study, based on fractal theory and a series of tests using the MTS815.02 rock mechanics test system, the classification and fractal characteristics of limestone specimen fragments are investigated. The results show that limestone specimens subjected to cyclic loading can generate more small-sized fragments...
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The genome (genes), epigenome, and environment work together from the earliest stages of human life to produce a phenotype of human health or disease. Epigenetic modifications, including among other things: DNA methylation, modifications of histones and chromatin structure, as well as functions of noncoding RNA, are coresponsible for specific patterns of gene expression. This refers also to mental disorders, including depressive disorders. Early childhood experiences accompanied by severe stressors...
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In recent years, polysulfone-based nanocomposite membranes have been widely used for contaminated water treatment because they comprise properties such as high thermal stability and chemical resistance. In this study, a polysulfone (PSf) nanocomposite membrane was fabricated using the wet-phase inversion method with the fusion of graphene oxide (GO) and alumina (Al2O3) nanoparticles. We also showed that GO-Al2O3 nanoparticles were synthesised successfully by using a one-pot hydrothermal method. The...
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Under the background of economic globalization, supply chain is becoming more and more complex, which is manifested in the instability of external environment. On the one hand, with the improvement of global environmental protection awareness, the government's policy tools for environmental impact (carbon tax) on the whole supply chain have become one of the major external problems faced by the supply chain enterprises; on the other hand, the intensification of competition between upstream and downstream...
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Study Design. Randomized clinical trial. Objectives. Early physical therapy (PT) with specific stabilization training has been shown to benefit individuals after lumbar spinal surgery but has not been studied in patients after cervical spine surgery. The primary purpose of this study was to compare clinical outcomes between early cervical spine stabilizer (ECS) training and usual care (UC) in patients after anterior cervical discectomy and fusion (ACDF) surgery. The secondary purpose was to determine...
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To evaluate the correlation between the changes in serum concentrations of cluster of differentiation-147 (scCD147) and chemotherapy outcome in patients with NSCLC and evaluate the combination of scCD147 with serum matrix metalloproteinase-9 (scMMP-9) levels in the prediction of chemotherapy response, eighty-two patients with advanced LC were enrolled. Newly diagnosed cases were treated with platinum-based chemotherapy. We measured scCD147 protein levels in LC cases by ELISA and used receiver operating...
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Using almost 10 years of observations of clouds and aerosols from the US Southern Great Plains (SGP) atmospheric observatory and the Semi-Arid Climate and Environment Observatory of Lanzhou University (SACOL) in China, the impact of aerosols on single-layer overcast clouds over continental land for different regimes were investigated. Atmospheric conditions at the two sites were first compared in an attempt to isolate the influence of aerosols on cloud properties from dynamic and thermodynamic influences....
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Aiming at the chaotic characteristics of underwater acoustic signal, a prediction model of grey wolf-optimized kernel extreme learning machine (OKELM) based on MVMD is proposed in this paper for short-term prediction of underwater acoustic signals. To solve the problem of K value selection in variational mode decomposition, a new K value selection method MVMD is proposed from the perspective of mutual information, which avoids the blindness of variational mode decomposition (VMD) in the preset modal...
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Purpose. To compare the efficacy between initial 3-monthly intravitreal conbercept monotherapy and combination intravitreal conbercept with photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV). Methods. This is a retrospective, comparative study which involved 65 PCV eyes of 65 patients. According to the therapeutic regimen, the PCV patients were divided into two groups: 32 eyes with naive PCV received a PDT after the first intravitreal injection of conbercept (IVC) followed by...
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In this paper, we establish the existence of at least three weak solutions for a parametric double eigenvalue quasi-linear elliptic -Kirchhoff-type potential system. Our approach is based on a variational method, and a three critical point theorem is obtained by Bonano and Marano.
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Ischemic cerebral stroke is a severe neurodegenerative disease with high mortality. Ischemia and reperfusion injury plays a fundamental role in ischemic cerebral stroke. To date, the strategy for ischemic cerebral stroke treatment is limited. In the present study, we aimed to investigate the effect of kaempferol (KFL), a natural flavonol, on cell injury induced by oxygen and glucose deprivation (OGD) and reoxygenation (OGD-reoxygenation) in PC12 cells. We found that KFL inhibited OGD-induced decrease...
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The human aging is marked by several body changes, including in bone mineral density (BMD). Research shows that microRNAs are important modulators of bone metabolism. The present research aims to analyze the whole blood concentration of 10 selected microRNAs (miRs) and their association with absolute and relative scores of BMD in specific osseous site of Brazilian very-old adults. Forty noninstitutionalized and apparently healthy, very old (≥80 years) outpatients were eligible for research. Anthropometry,...
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Free radicals are chemical species (atoms, molecules, or ions) containing one or more unpaired electrons in their external orbitals and generally display a remarkable reactivity. The evidence of their existence was obtained only at the beginning of the 20th century. Chemists gradually ascertained the involvement of free radicals in organic reactions and, in the middle of the 20th century, their production in biological systems. For several decades, free radicals were thought to cause exclusively...
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Microstructural evolutions of EK61 superalloy during long-term aging until 1000 h at 700°C and 750°C, respectively, are studied by combination of Scanning Electron Microscope (SEM) and Transmission Electron Microscope (TEM). Impact fracture morphologies after aging for different time are observed by the SEM. The microstructure is found to be relatively stable during aging at 700°C, and the fracture morphologies are characterized by transgranular fracture. At 750°C, the coarsening of γ phase leads...
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Nowadays, scholar recommender systems often recommend academic papers based on users’ personalized retrieval demands. Typically, a recommender system analyzes the keywords typed by a user and then returns his or her preferred papers, in an efficient and economic manner. In practice, one paper often contains partial keywords that a user is interested in. Therefore, the recommender system needs to return the user a set of papers that collectively covers all the queried keywords. However, existing recommender...
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Composite has been widely used in various fields due to its advanced performance. To reveal the relation between the mechanical properties of the composite and that of each individual component, finite element analysis (FEA) has usually been adopted. In this study, in order to predict the mechanical properties of hard coating on a soft polymer, the response of this coating system during nanoindentation was modelled. Various models, such as a viscoelastic model and fitting model, were adopted to analyse...
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This research proposes an integrated high-frequency (HF) and ultrahigh-frequency (UHF) passive radio frequency identification (RFID) tag antenna for near-field (13.56 MHz) and far-field (920–925 MHz) communication. This tag antenna is advantageous for the applications with lossy material in the near-field communication and mitigates polarization loss in the far-field communications. The HF-RFID tag antenna is of square spiral structure, and the circularly polarized UHF-RFID structure consists of...
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Extrapyramidal side effects of psychotropic medicines are usually experienced by patients in the first few weeks of initiating therapy. Patients stabilized on these medications who present with distressing complaints akin to akathisia may be triggered by other factors. This report presents two cases of drug-drug-induced akathisia. Case A is a patient with schizophrenia who was being managed with risperidone 2 mg tablet daily for the past 3 years. She fell ill and reported to a nearby clinic where...
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Manganese accumulation in the central nervous system creates clinical symptoms of cognitive dysfunction, behavioral changes, and movement disorders resembling Parkinson’s disease. Radiographic features of this rare clinical entity include symmetric T1 hyperintensities in the bilateral globus pallidi, with corresponding hypointensities on T2-weighted images. Total parenteral nutrition (TPN) is an increasingly used potentially lifesaving therapy for patients who cannot tolerate enteral nutrition. However,...
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Background. Immune checkpoint inhibitors (ICI) have changed the landscape in the treatment of a number of cancers. Immune-related adverse events (irAEs) have emerged as a serious clinical problem with the use of ICI. Methods. All oncology patients diagnosed with pulmonary complications secondary to ICI at Mayo Clinic Rochester from January 1, 2012 to December 31, 2018 were reviewed. Demographics, comorbidities, smoking, and oncologic history were analyzed. Results. A total of 10 patients developed...
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In order to predict the residual gas content in coal seam in front of roadway advancing face accurately and rapidly, an improved prediction method based on both drilling cuttings indices and bat algorithm optimizing extreme learning machine (BA-ELM) was proposed. The test indices of outburst prevention measures (drilling cuttings indices, residual gas content in coal seam) during roadway advancing in Yuecheng coal mine were first analyzed. Then, the correlation between drilling cuttings indices and...
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The aim of the study was to determine whether plasma levels of total glycosaminoglycans (GAGs), matrix metalloproteinases (MMPs) (MMP-3, MMP-10), and their tissue inhibitors (TIMPs) (TIMP-1, TIMP-2) as well as transforming growth factor β (TGF-β) differ in the patients with systemic sclerosis (SSc) in relation to the healthy subjects. Plasma samples were obtained from 106 people (64 patients with SSc and 42 healthy individuals) and measured for MMP-3, MMP-10, TIMP-1, TIMP-2, and TGF-β levels using...
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Background. Whether elevated triglyceride (TG) levels during pregnancy were a biomarker for postpartum abnormal glucose metabolism (AGM) in women with previous gestational diabetes mellitus (GDM) remained unknown. The aim of this study was to investigate the association between TG levels during the second trimester and postpartum AGM in GDM women. Methods. This was a retrospective cohort study including 513 GDM women. A 75 g oral glucose tolerance test (OGTT) was performed, and lipid levels were...
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Clavicular fractures are some of the most common bone injuries in the paediatric population, yet the rates of nonunion are very low under 18 years. To the best of our knowledge, posttraumatic nonunion of the clavicle in a paediatric population is rarely reported. We report the case of an 11-year-old girl who presented with a nondislocated fracture of the midshaft to the proximal third of the right clavicle. Initial conservative treatment by sling immobilization demonstrated radiologically confirmed...
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ObjectivesTo investigate prevalence of mental health conditions, sensory impairments and physical disability in children, adults and older adults with co-occurring intellectual disabilities and autism, given its frequent co-occurrence, compared with the general population. DesignWhole country cohort study. SettingGeneral community. Participants5709 people with co-occurring intellectual disabilities and autism, compared with 5 289 694 other people. Outcome measuresRates and ORs with 95% CIs...
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ObjectivesTo assess the diagnostic value of non-acute chest pain characteristics for coronary artery disease in women and men referred to outpatient cardiology clinics. Design and settingThis is an observational study performed at outpatient cardiology centres of the Netherlands. ParticipantsThe study population consisted of 1028 patients with non-acute chest pain (505 women). Analysis and resultsTwenty-four women (5%) and 75 men (15%) were diagnosed with coronary artery disease by invasive...
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ObjectiveThe WHO recommends responsive caregiving and early learning (RCEL) interventions to improve early child development (ECD), and to achieve the Sustainable Development Goals’ vision of a world where all children thrive. Implementation of RCEL programmes in low and middle-income countries (LMIC) requires evidence to inform decisions about human resources and curricula content. We aimed to describe human resources and curricula content for implementation of RCEL projects across diverse LMICs,...
1h
IntroductionThe peripheral nerves of patients with diabetes are often pathologically swollen, which results in entrapment at places of anatomical narrowing. This results in nerve dysfunction. Surgical treatment of compression neuropathies in the lower extremities (lower extremity nerve decompression (LEND)) results in relief of symptoms and gain in peripheral nerve function, which may lead to less sensory loss (short term) and less associated detrimental effects including foot ulceration and amputations,...
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