Pharmaceutics, Vol. 12, Pages 389: Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing Pharmaceutics doi: 10.3390/pharmaceutics12040389 Authors: Kaj E. C. Blokland David W. Waters Michael Schuliga Jane Read Simon D. Pouwels Christopher L. Grainge Jade Jaffar Glen Westall Steven E. Mutsaers Cecilia M. Prêle Janette K. Burgess Darryl A. Knight Idiopathic pulmonary fibrosis (IPF) is a progressive...
Fri Apr 24, 2020 03:00
Pharmaceutics, Vol. 12, Pages 390: Acamprosate is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug–Drug Interactions Pharmaceutics doi: 10.3390/pharmaceutics12040390 Authors: Irina E. Antonescu Maria Karlgren Maria L. Pedersen Ivailo Simoff Christel A.S. Bergström Sibylle Neuhoff Per Artursson Bente Steffansen Carsten Uhd Nielsen Acamprosate is an anionic drug substance...
Fri Apr 24, 2020 03:00
Pharmacy, Vol. 8, Pages 73: A Qualitative Exploration to Understand Access to Pharmacy Medication Reviews: Views from Marginalized Patient Groups Pharmacy doi: 10.3390/pharmacy8020073 Authors: Latif Mandane Ali Ghumra Gulzar Background: Vulnerable patients from marginalized groups (e.g., people with disabilities, people experiencing homelessness, black and minority ethnic communities) experience higher rates of ill-health, inequitable access to healthcare and low engagement...
Sun Apr 26, 2020 03:00
Plants, Vol. 9, Pages 553: Phytic Acid and Mineral Biofortification Strategies: From Plant Science to Breeding and Biotechnological Approaches Plants doi: 10.3390/plants9050553 Authors: Eleonora Cominelli Roberto Pilu Francesca Sparvoli Mineral deficiencies, particularly for iron and zinc, affect over two billion people worldwide, mainly in developing countries where diets are based on the consumption of staple crops. Mineral biofortification includes different approaches aimed...
Sun Apr 26, 2020 03:00
Plants, Vol. 9, Pages 552: The Product Specificities of Maize Terpene Synthases TPS4 and TPS10 Are Determined both by Active Site Amino Acids and Residues Adjacent to the Active Site Plants doi: 10.3390/plants9050552 Authors: Tobias G. Köllner Jörg Degenhardt Jonathan Gershenzon Terpene synthases make up a large family of enzymes that convert prenyl diphosphates into an enormous variety of terpene skeletons. Due to their electrophilic reaction mechanism—which involves...
Sun Apr 26, 2020 03:00
Plants, Vol. 9, Pages 551: Mutagenic Effect of Three Ion Beams on Rice and Identification of Heritable Mutations by Whole Genome Sequencing Plants doi: 10.3390/plants9050551 Authors: Yunchao Zheng Shan Li Jianzhong Huang Haowei Fu Libin Zhou Yoshiya Furusawa Qingyao Shu High-energy ion beams are known to be an effective and unique type of physical mutagen in plants. However, no study on the mutagenic effect of argon (Ar) ion beam radiation on rice has been reported....
Sun Apr 26, 2020 03:00
Plants, Vol. 9, Pages 550: Naringenin Regulates Doxorubicin-Induced Liver Dysfunction: Impact on Oxidative Stress and Inflammation Plants doi: 10.3390/plants9040550 Authors: Adil Farooq Wali Summya Rashid Shahzada Mudasir Rashid Mushtaq Ahmad Ansari Mohammad Rashid Khan Nazrul Haq Dhafer Yahya Alhareth Ajaz Ahmad Muneeb U. Rehman Doxorubicin (Dox) is an operational and largely used anticancer drug, used to treat an array of malignancies. Nonetheless, its beneficial...
Fri Apr 24, 2020 03:00
Publications, Vol. 8, Pages 23: A Vertical Cooperation Model to Manage Digital Collections and Institutional Resources Publications doi: 10.3390/publications8020023 Authors: Maness Pham Reyes Rynhart The technology space of the University of Denver Libraries to manage digital collections and institutional resources isn’t relegated to one department on campus – rather, it distributed across a network of collaborators with the skills and expertise to provide...
Sun Apr 26, 2020 03:00
Resources, Vol. 9, Pages 52: Geotourism in the Cilento, Vallo di Diano and Alburni UNESCO Global Geopark (Southern Italy): The Middle Bussento Karst System Resources doi: 10.3390/resources9050052 Authors: Valente Santo Guida Santangelo In this paper we want to stress the role of geotourism as a means to promote environmental education and, on occasion, as a way to increase the touristic interest of an area. Geoparks are certainly the territory where geotourism can be best...
Sun Apr 26, 2020 03:00
Resources, Vol. 9, Pages 50: Development of Digital Subterranean Models for Real-Time Open Cut Horizon Control Resources doi: 10.3390/resources9040050 Authors: Andrew D. Strange Zak Jecny A reliable coal seam sensing system is required to improve the productivity of selective mining in open-cut mining operations. A prototype system based upon commercial ground penetrating radar equipment, which measures coal thickness from the top of an exposed surface down to an underlying coal-interburden...
Fri Apr 24, 2020 03:00
Resources, Vol. 9, Pages 51: Fusion of Remote Sensing and Applied Geophysics for Sinkholes Identification in Tabular Middle Atlas of Morocco (the Causse of El Hajeb): Impact on the Protection of Water Resource Resources doi: 10.3390/resources9040051 Authors: Anselme Muzirafuti Mustapha Boualoul Giovanni Barreca Abdelhamid Allaoui Hmad Bouikbane Stefania Lanza Antonio Crupi Giovanni Randazzo The Causse of El Hajeb belongs to the Tabular Middle Atlas (TMA), in which...
Fri Apr 24, 2020 03:00
Robotics, Vol. 9, Pages 29: Adjustable and Adaptive Control for an Unstable Mobile Robot Using Imitation Learning with Trajectory Optimization Robotics doi: 10.3390/robotics9020029 Authors: Christian Dengler Boris Lohmann In this contribution, we develop a feedback controller in the form of a parametric function for a mobile inverted pendulum. The control both stabilizes the system and drives it to target positions with target orientations. A design of the controller based only on...
Sat Apr 25, 2020 03:00
Sci, Vol. 2, Pages 30: On Singular Perturbation of Neutron Point Kinetics in the Dynamic Model of a PWR Nuclear Power Plant Sci doi: 10.3390/sci2020030 Authors: Xiangyi Chen Asok Ray This short communication makes use of the principle of singular perturbation to approximate the ordinary differential equation (ODE) of prompt neutron (in the point kinetics model) as an algebraic equation. This approximation is shown to yield a large gain in computational efficiency without compromising...
Sun Apr 26, 2020 03:00
Sci. Pharm., Vol. 88, Pages 22: Is the Botryococcus braunii Dry Biomass an Adjuvant for Anti-UVB Topical Formulations? Scientia Pharmaceutica doi: 10.3390/scipharm88020022 Authors: Ariede Morocho-Jácome Candido Lourenço Kato Lima Rosado Velasco Carvalho Baby Several topical products have been developed to avoid the harmful effects from ultraviolet (UV) radiation, such as sunscreens. Research for actives from natural sources is increasing due to the...
Sun Apr 26, 2020 03:00
Social Sciences, Vol. 9, Pages 61: Overselling Globalization: The Misleading Conflation of Economic Globalization and Immigration, and the Subsequent Backlash Social Sciences doi: 10.3390/socsci9050061 Authors: Castañeda Shemesh Many think that immigration is something caused by globalization, and some subsequently blame immigrants for the increased inequalities produced by economic globalization. Xenophobic nationalism has gained popularity around the world, further increasing...
Sun Apr 26, 2020 03:00
Social Sciences, Vol. 9, Pages 60: Going by an English Name: The Adoption and Use of English Names by Young Taiwanese Adults Social Sciences doi: 10.3390/socsci9040060 Authors: Ivona Baresova Marcel Pikhart It is easy to understand why Taiwanese students play the part of the name assigned to them in English class, but why do so many of them continue to use this name long after their school years? A survey of young Taiwanese adults, with follow-up interviews, investigated how and why...
Fri Apr 24, 2020 03:00
Sports, Vol. 8, Pages 57: The Effects of Postprandial Resistance Exercise on Blood Glucose and Lipids in Prediabetic, Beta-Thalassemia Major Patients Sports doi: 10.3390/sports8050057 Authors: Kalliopi Georgakouli Alexandra Stamperna Chariklia K. Deli Niki Syrou Dimitrios Draganidis Ioannis G. Fatouros Athanasios Z. Jamurtas Insulin resistance and diabetes mellitus are common consequences of iron overload in the pancreas of beta-thalassemia major (BTM) patients. Moreover,...
Sun Apr 26, 2020 03:00
Sports, Vol. 8, Pages 56: Strategies and Solutions for Team Sports Athletes in Isolation due to COVID-19 Sports doi: 10.3390/sports8040056 Authors: Igor Jukic Julio Calleja-González Francesc Cos Francesco Cuzzolin Jesús Olmo Nicolas Terrados Nenad Njaradi Roberto Sassi Bernardo Requena Luka Milanovic Ivan Krakan Kostas Chatzichristos Pedro E. Alcaraz In December of 2019, there was an outbreak of a severe acute respiratory syndrome caused by the Coronavirus...
Fri Apr 24, 2020 03:00
Toxins, Vol. 12, Pages 280: Rapid and Label-Free Immunosensing of Shiga Toxin Subtypes with Surface Plasmon Resonance Imaging Toxins doi: 10.3390/toxins12050280 Authors: Bin Wang Bosoon Park Jing Chen Xiaohua He Shiga toxin-producing Escherichia coli (STEC) are responsible for gastrointestinal diseases reported in numerous outbreaks around the world as well as in the United States. Current detection methods have limitation to implement for rapid field-deployable detection with...
Sun Apr 26, 2020 03:00
Toxins, Vol. 12, Pages 279: Staphylococcus aureus Pathogenicity in Cystic Fibrosis Patients—Results from an Observational Prospective Multicenter Study Concerning Virulence Genes, Phylogeny, and Gene Plasticity Toxins doi: 10.3390/toxins12050279 Authors: Jonas Lange Kathrin Heidenreich Katharina Higelin Kristina Dyck Vanessa Marx Christian Reichel Willem van Wamel Martijn den Reijer Dennis Goerlich Barbara C. Kahl
Sun Apr 26, 2020 03:00
Toxins, Vol. 12, Pages 278: Accumulation and Elimination of Tetrodotoxin in the Pufferfish Takifugu obscurus by Dietary Administration of the Wild Toxic Gastropod Nassarius semiplicata Toxins doi: 10.3390/toxins12050278 Authors: Xiaojun Zhang Jingjing Zong Si Chen Menglong Li Yibo Lu Ruirui Wang Hanxiang Xu To investigate pufferfish accumulation, elimination, and distribution of tetrodotoxin (TTX), Takifugu obscurus was fed with wild TTX-containing gastropod Nassarius...
Sat Apr 25, 2020 03:00
Toxins, Vol. 12, Pages 276: Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays Toxins doi: 10.3390/toxins12050276 Authors: Maren Schenke Brit-Maren Schjeide Gerhard P. Püschel Bettina Seeger Botulinum neurotoxins (BoNTs) are potent neurotoxins produced by bacteria, which inhibit neurotransmitter release, specifically in their physiological target known as motor neurons (MNs). For the...
Sat Apr 25, 2020 03:00
Toxins, Vol. 12, Pages 277: Botulinum Toxin Effects on Sensorimotor Integration in Focal Dystonias Toxins doi: 10.3390/toxins12050277 Authors: Maria Ilenia De Bartolo Nicoletta Manzo Gina Ferrazzano Viola Baione Daniele Belvisi Giovanni Fabbrini Alfredo Berardelli Antonella Conte (1) Background: In dystonia, the somatosensory temporal discrimination threshold (STDT) is abnormally increased at rest and higher and longer-lasting during movement execution in comparison...
Sat Apr 25, 2020 03:00
Urban Science, Vol. 4, Pages 20: Contradictions of Transit-Oriented Development in Low-Income Neighborhoods: The Case Study of Rosengård in Malmö, Sweden Urban Science doi: 10.3390/urbansci4020020 Authors: Laleh Derakhti Guy Baeten Transit-oriented development (TOD) has become a leading model of urban planning worldwide that promises to meet a broad range of local and regional objectives: improving mobility, expanding ridership, attracting investment, reducing urban poverty, improving...
Sat Apr 25, 2020 03:00
Vaccines, Vol. 8, Pages 201: A Durable Relationship: Respiratory Syncytial Virus Bronchiolitis and Asthma past Their Golden Anniversary Vaccines doi: 10.3390/vaccines8020201 Authors: Ignacio Esteban Renato T. Stein Fernando P. Polack Numerous preventive strategies against respiratory syncytial virus (RSV) are undergoing late stage evaluation in humans and, in addition to their intended benefit for acute illness, may impact long term consequences of infection in infants. Severe...
Sun Apr 26, 2020 03:00
Vaccines, Vol. 8, Pages 200: Comparison of the Immunogenicity and Safety of Three Enhanced Inactivated Poliovirus Vaccines from Different Manufacturers in Healthy Korean Infants: A Prospective Multicenter Study Vaccines doi: 10.3390/vaccines8020200 Authors: Kwak Ma Park Shin Choi Lee Eun Hong Kim The enhanced inactivated poliovirus vaccine was first introduced in 2002, and several inactivated poliovirus vaccines are licensed in Korea. Reliable data by...
Sun Apr 26, 2020 03:00
Vaccines, Vol. 8, Pages 199: Zebrafish pten Genes Play Relevant but Distinct Roles in Antiviral Immunity Vaccines doi: 10.3390/vaccines8020199 Authors: Pereiro Figueras Novoa The PTEN (phosphatase and TENsin homolog on chromosome 10) gene encodes a bifunctional phosphatase that acts as a tumor suppressor. However, PTEN has been implicated in different immune processes, including autophagy, inflammation, regulation of natural killer (NK) cell cytolytic activity and type I interferon...
Sun Apr 26, 2020 03:00
Vaccines, Vol. 8, Pages 198: Mycolicibacterium brumae Is a Safe and Non-Toxic Immunomodulatory Agent for Cancer Treatment Vaccines doi: 10.3390/vaccines8020198 Authors: Marc Bach-Griera Víctor Campo-Pérez Sandra Barbosa Sara Traserra Sandra Guallar-Garrido Laura Moya-Andérico Paula Herrero-Abadía Marina Luquin Rosa Maria Rabanal Eduard Torrents Esther Julián Intravesical Mycobacterium bovis Bacillus Calmette–Guérin (BCG) immunotherapy...
Sat Apr 25, 2020 03:00
Vaccines, Vol. 8, Pages 197: Construction and Immunogenicity of a Novel Multivalent Vaccine Prototype Based on Conserved Influenza Virus Antigens Vaccines doi: 10.3390/vaccines8020197 Authors: Anna Kirsteina Inara Akopjana Janis Bogans Ilva Lieknina Juris Jansons Dace Skrastina Tatjana Kazaka Kaspars Tars Irina Isakova-Sivak Daria Mezhenskaya Tatiana Kotomina Victoria Matyushenko Larisa Rudenko Andris Kazaks Influenza, an acute, highly contagious...
Fri Apr 24, 2020 03:00
Vaccines, Vol. 8, Pages 196: Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T-cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T-Cell Responses and Protect Mice against Both Infections Vaccines doi: 10.3390/vaccines8020196 Authors: Irina Isakova-Sivak Victoria Matyushenko Ekaterina Stepanova Anastasia Matushkina Tatiana Kotomina Daria Mezhenskaya Polina Prokopenko Igor Kudryavtsev Pavel Kopeykin Konstantin Sivak Larisa...
Fri Apr 24, 2020 03:00
Vaccines, Vol. 8, Pages 195: Vaccination with Alpha-Gal Protects Against Mycobacterial Infection in the Zebrafish Model of Tuberculosis Vaccines doi: 10.3390/vaccines8020195 Authors: Iván Pacheco Marinela Contreras Margarita Villar María Angeles Risalde Pilar Alberdi Alejandro Cabezas-Cruz Christian Gortázar José de la Fuente The alpha-Gal syndrome (AGS) is associated with tick bites that can induce in humans high levels of IgE antibodies against the carbohydrate...
Fri Apr 24, 2020 03:00
Veterinary Sciences, Vol. 7, Pages 53: In Vitro Inhibiting Effects of Three Fungal Species on Eggs of Donkey Gastrointestinal Strongyles Veterinary Sciences doi: 10.3390/vetsci7020053 Authors: Michela Maestrini Simona Nardoni Francesca Mancianti Simone Mancini Stefania Perrucci Recently, donkeys have gained popularity mainly due to the use of donkey milk by the cosmetic industry and for human consumption. Gastrointestinal strongyles (GIS) are considered a potential cause...
Sat Apr 25, 2020 03:00
Veterinary Sciences, Vol. 7, Pages 52: Effect of Oral Administration of 1,3-1,6 β-Glucans in DWV Naturally Infected Newly Emerged Bees (Apis mellifera L.) Veterinary Sciences doi: 10.3390/vetsci7020052 Authors: Antonio Felicioli Mario Forzan Simona Sagona Paola D’Agostino Diego Baido Baldassare Fronte Maurizio Mazzei Honeybee pathogens have an important role in honeybee colony mortality and colony losses; most of them are widely spread and necessitate worldwide solutions...
Sat Apr 25, 2020 03:00
Viruses, Vol. 12, Pages 485: Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt Viruses doi: 10.3390/v12050485 Authors: Ahmed El Taweel Ahmed Kandeil Ahmed Barakat Omar Alfaroq Rabiee Ghazi Kayali Mohamed Ahmed Ali Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses....
Sun Apr 26, 2020 03:00
Viruses, Vol. 12, Pages 486: Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19 Viruses doi: 10.3390/v12050486 Authors: Kumar Zhi Mukherji Gerth In January 2020, Chinese health agencies reported an outbreak of a novel coronavirus-2 (CoV-2) which can lead to severe acute respiratory syndrome (SARS). The virus, which belongs to the coronavirus family (SARS-CoV-2), was named coronavirus disease 2019 (COVID-19) and declared...
Sun Apr 26, 2020 03:00
Viruses, Vol. 12, Pages 487: Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections Viruses doi: 10.3390/v12050487 Authors: Yifan Xing Zeyu Wen Wei Gao Zhekai Lin Jin Zhong Yaming Jiu Virus infection has drawn extensive attention since it causes serious or even deadly diseases, consequently inducing a series of social and public health problems. Caveolin-1 is the most important structural protein of caveolae, a membrane invagination widely known for...
Sun Apr 26, 2020 03:00
Viruses, Vol. 12, Pages 484: Significant Differences in RNA Structure Destabilization by HIV-1 GagDp6 and NCp7 Proteins Viruses doi: 10.3390/v12050484 Authors: Micah J. McCauley Ioulia Rouzina Jasmine Li Megan E. Núñez Mark C. Williams Retroviral nucleocapsid (NC) proteins are nucleic acid chaperones that play distinct roles in the viral life cycle. During reverse transcription, HIV-1 NC facilitates the rearrangement of nucleic acid secondary structures, allowing the transactivation...
Sat Apr 25, 2020 03:00
Viruses, Vol. 12, Pages 482: Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane Viruses doi: 10.3390/v12040482 Authors: Kaveesha J. Wijesinghe Luke McVeigh Monica L. Husby Nisha Bhattarai Jia Ma Bernard S. Gerstman Prem P. Chapagain Robert V. Stahelin Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever....
Fri Apr 24, 2020 03:00
Viruses, Vol. 12, Pages 483: Microtubule Retrograde Motors and Their Role in Retroviral Transport Viruses doi: 10.3390/v12040483 Authors: Gianfranco Pietrantoni Rodrigo Ibarra-Karmy Gloria Arriagada Following entry into the host cell, retroviruses generate a dsDNA copy of their genomes via reverse transcription, and this viral DNA is subsequently integrated into the chromosomal DNA of the host cell. Before integration can occur, however, retroviral DNA must be transported to the...
Fri Apr 24, 2020 03:00
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