Microorganisms, Vol. 8, Pages 619: Monitoring the Functionality and Stress Response of Yeast Cells Using Flow Cytometry Microorganisms doi: 10.3390/microorganisms8040619 Authors: Stephan Sommer Throughout fermentation, yeast faces continuously changing medium conditions and reacts by adapting its metabolism. The adaptation is a critical process and is dependent on the accurate functioning of the cell. A stable membrane potential, which is, among other roles, responsible for protecting...
Microorganisms, Vol. 8, Pages 618: Genetic Variation in Caenorhabditis elegans Responses to Pathogenic Microbiota Microorganisms doi: 10.3390/microorganisms8040618 Authors: Yuqing Huang Jan E. Kammenga The bacterivorous nematode Caenorhabditis elegans is an important model species for understanding genetic variation of complex traits. So far, most studies involve axenic laboratory settings using Escherichia coli as the sole bacterial species. Over the past decade, however, investigations...
Microorganisms, Vol. 8, Pages 615: Cytomegalovirus Strain TB40/E Restrictions and Adaptations to Growth in ARPE-19 Epithelial Cells Microorganisms doi: 10.3390/microorganisms8040615 Authors: Mai Vo Alexis Aguiar Michael A. McVoy Laura Hertel Despite displaying broad tropism in vivo, human cytomegalovirus (CMV) contained in bodily fluids replicates inefficiently in most cultured cell types except fibroblasts. As propagation in fibroblasts leads to the accumulation of genomic...
Microorganisms, Vol. 8, Pages 614: Microbial Resource Management for Ex Situ Biomethanation of Hydrogen at Alkaline pH Microorganisms doi: 10.3390/microorganisms8040614 Authors: Washington Logroño Denny Popp Sabine Kleinsteuber Heike Sträuber Hauke Harms Marcell Nikolausz Biomethanation is a promising solution to convert H2 (produced from surplus electricity) and CO2 to CH4 by using hydrogenotrophic methanogens. In ex situ biomethanation with mixed cultures, homoacetogens...
Microorganisms, Vol. 8, Pages 616: Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces Microorganisms doi: 10.3390/microorganisms8040616 Authors: Chung Thanh Nguyen Dipesh Dhakal Van Thuy Thi Pham Hue Thi Nguyen Jae-Kyung Sohng Streptomyces spp. are prolific sources of valuable natural products (NPs) that are of great interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics,...
Molbank, Vol. 2020, Article M1126: 3,5-Dithiatricyclo[5.2.1.02,6]decan-4-one Molbank doi: 10.3390/M1126 Authors: R. Alan Aitken Neil S. Keddie Alexandra M. Z. Slawin The x-ray structure of the title compound has been determined and the structure shows an exo-configured planar dithiolanone ring. This is in contrast to the few previous dithiolanones to be characterised crystallographically, which are all twisted.
Molbank, Vol. 2020, Article M1127: Microwave-Assisted Synthesis and Fluorescent Properties of 4-Phenyl-1,8-naphthalimide Molbank doi: 10.3390/M1127 Authors: Frank Betancourt James Helmkay Hongbin Yan 4-Phenyl-1,8-naphthalimide was synthesized by imidation of commercially available 4-bromo-1,8-naphthalic anhydride, followed by Suzuki coupling with phenyl boronic acid, both under microwave heating. The microwave-assisted reactions were found to be faster and more efficient than reactions...
Molecules, Vol. 25, Pages 2024: Preclinical Incorporation Dosimetry of [18F]FACH—A Novel 18F-Labeled MCT1/MCT4 Lactate Transporter Inhibitor for Imaging Cancer Metabolism with PET Molecules doi: 10.3390/molecules25092024 Authors: Bernhard Sattler Mathias Kranz Barbara Wenzel Nalin T. Jain Rareş-Petru Moldovan Magali Toussaint Winnie Deuther-Conrad Friedrich-Alexander Ludwig Rodrigo Teodoro Tatjana Sattler Masoud Sadeghzadeh Osama Sabri Peter Brust Overexpression...
Molecules, Vol. 25, Pages 2023: Biofilm Eradication Using Biogenic Silver Nanoparticles Molecules doi: 10.3390/molecules25092023 Authors: María Belén Estevez Sofía Raffaelli Scott G. Mitchell Ricardo Faccio Silvana Alborés Microorganisms offer an alternative green and scalable technology for the synthesis of value added products. Fungi secrete high quantities of bioactive substances, which play dual-functional roles as both reducing and stabilizing agents in the synthesis...
Molecules, Vol. 25, Pages 2025: Identification of Transient Receptor Potential Vanilloid 3 Antagonists from Achillea alpina L. and Separation by Liquid-Liquid-Refining Extraction and High-Speed Counter-Current Chromatography Molecules doi: 10.3390/molecules25092025 Authors: Shi-Wei Sun Rong-Rong Wang Xiao-Ying Sun Jia-He Fan Hang Qi Yang Liu Guo-Qing Qin Wei Wang Bioassay-guided fractionation of the ethanol extract of whole herbs of Achillea alpina led to the isolation...
Molecules, Vol. 25, Pages 2021: Phytocomplex Characterization and Biological Evaluation of Powdered Fruits and Leaves from Elaeagnus angustifolia Molecules doi: 10.3390/molecules25092021 Authors: Simone Carradori Francesco Cairone Stefania Garzoli Giancarlo Fabrizi Antonia Iazzetti Anna Maria Giusti Luigi Menghini Sengul Uysal Gunes Ak Gokhan Zengin Stefania Cesa Fully ripe fruits and mature leaves of Elaeagnus angustifolia were harvested and analyzed by...
Molecules, Vol. 25, Pages 2022: Phytochemical Profile and Biological Activity of Endemic Sideritis sipylea Boiss. in North Aegean Greek Islands Molecules doi: 10.3390/molecules25092022 Authors: Axiotis Petrakis Halabalaki Mitakou Sideritis sipylea Boiss. is an endemic plant of the Mediterranean basin that is distributed in the Greek islands of the North Aegean Sea, i.e., Lesvos, Chios, Samos, and Ikaria, and in the West and Middle peninsula of Turkey. It is considered an...
Molecules, Vol. 25, Pages 2020: Preconditioning of Adipose-Derived Mesenchymal Stem-Like Cells with Eugenol Potentiates Their Migration and Proliferation In Vitro and Therapeutic Abilities in Rat Hepatic Fibrosis Molecules doi: 10.3390/molecules25092020 Authors: Moustafa Fathy Motonori Okabe Eman M. Othman Heba M. Saad Eldien Toshiko Yoshida Mesenchymal stem cells (MSCs) have considerable therapeutic abilities in various disorders, including hepatic fibrosis. They may be...
Molecules, Vol. 25, Pages 2018: A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors Molecules doi: 10.3390/molecules25092018 Authors: Francesca Giulia Nacca Bonifacio Monti Eder João Lenardão Paul Evans Claudio Santi In this work, we focused our attention on seleno-Michael type reactions. These were performed using zinc-selenolates generated in situ from diphenyl diselenide 1, 1,2-bis(3-phenylpropyl)diselenide 30, and protected selenocystine 31 via an...
Molecules, Vol. 25, Pages 2019: Simple Synthesis of 17-β-O-hemisuccinate of Stanozolol for Immunoanalytical Methods Molecules doi: 10.3390/molecules25092019 Authors: Silvana Casati Roberta Ottria Pierangela Ciuffreda The use of doping in sports is a global problem that affects athletes around the world. Among the different methods developed to detect doping agents in biological samples, there are antibody-based methods that need an appropriate hapten design. Steroids with a hydroxyl...
Molecules, Vol. 25, Pages 2017: Self-Assembling Behavior of pH-Responsive Peptide A6K without End-Capping Molecules doi: 10.3390/molecules25092017 Authors: Peng Zhang Fenghuan Wang Yuxuan Wang Shuangyang Li Sai Wen A short self-assembly peptide A6K (H2N−AAAAAAK−OH) with unmodified N− and C−terminus was designed, and the charge distribution model of this short peptide at different pH was established by computer simulation. The pH of...
Molecules, Vol. 25, Pages 2016: Current Trends in the Application of Nanomaterials for the Removal of Emerging Micropollutants and Pathogens from Water Molecules doi: 10.3390/molecules25092016 Authors: Kokkinos Mantzavinos Venieri Water resources contamination has a worldwide impact and is a cause of global concern. The need for provision of clean water is becoming more and more demanding. Nanotechnology may support effective strategies for the treatment, use and reuse of water...
Molecules, Vol. 25, Pages 2015: Recent Progress of Cu-Catalyzed Azide-Alkyne Cycloaddition Reactions (CuAAC) in Sustainable Solvents: Glycerol, Deep Eutectic Solvents, and Aqueous Media Molecules doi: 10.3390/molecules25092015 Authors: Noel Nebra Joaquín García-Álvarez This mini-review presents a general overview of the progress achieved during the last decade on the amalgamation of CuAAC processes (copper-catalyzed azide-alkyne cycloaddition) with the employment of sustainable solvents...
Molecules, Vol. 25, Pages 2008: On the Enhanced Accuracy of Kinetic Curve Building in Supercritical Fluid Extraction from Aroma Plants Using a New 3D-Printed Extract Collection Device Molecules doi: 10.3390/molecules25092008 Authors: Denis Prokopchuk Oleg Pokrovskiy Accurate collection of extracted material represents a technical problem in supercritical fluid extraction because trapping should be performed in severe conditions of rapidly moving and freezing expanded fluid. We have...
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