JCM, Vol. 9, Pages 1234: Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide Analysis Journal of Clinical Medicine doi: 10.3390/jcm9041234 Authors: Fauchier Bodin Bisson Herbert Spiesser Clementy Babuty Chao Lip Background: We hypothesized that the change in stroke risk profile between baseline and follow-up may be a better predictor of ischemic stroke than the baseline stroke risk determination...
Fri Apr 24, 2020 03:00
JCM, Vol. 9, Pages 1235: Rethinking Radical Surgery in Interval Debulking Surgery for Advanced-Stage Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy Journal of Clinical Medicine doi: 10.3390/jcm9041235 Authors: Yong Jae Lee Jung-Yun Lee Eun Ji Nam Sang Wun Kim Sunghoon Kim Young Tae Kim The aim of this study is to evaluate the effects on survival outcomes of the disease burden before interval debulking surgery (IDS), surgical complexity, and residual disease...
Fri Apr 24, 2020 03:00
JCM, Vol. 9, Pages 1229: Influence of Anesthesia and Clinical Variables on the Firing Rate, Coefficient of Variation and Multi-Unit Activity of the Subthalamic Nucleus in Patients with Parkinson’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9041229 Authors: Michael J. Bos Ana Maria Alzate Sanchez Raffaella Bancone Yasin Temel Bianca T.A. de Greef Anthony R. Absalom Erik D. Gommer Vivianne H.J.M. van Kranen-Mastenbroek Wolfgang F. Buhre Mark J. Roberts Marcus...
Fri Apr 24, 2020 03:00
JCM, Vol. 9, Pages 1230: Post-Traumatic Sepsis Is Associated with Increased C5a and Decreased TAFI Levels Journal of Clinical Medicine doi: 10.3390/jcm9041230 Authors: Vollrath Marzi Herminghaus Lustenberger Relja Background: Sepsis frequently occurs after major trauma and is closely associated with dysregulations in the inflammatory/complement and coagulation system. Thrombin-activatable fibrinolysis inhibitor (TAFI) plays a dual role as an anti-fibrinolytic and anti-inflammatory...
Fri Apr 24, 2020 03:00
JCM, Vol. 9, Pages 1227: Safety Profile of Biologics Used in Rheumatology: An Italian Prospective Pharmacovigilance Study Journal of Clinical Medicine doi: 10.3390/jcm9041227 Authors: Barbieri Cicala Cutroneo Gerratana Palleria De Sarro Vero Iannone Manti Russo De Sarro Atzeni Spina Post-marketing surveillance activities are essential to detect the risk/benefit profile of biologic disease-modifying antirheumatic drugs (bDMARDs) in inflammatory...
Fri Apr 24, 2020 03:00
JCM, Vol. 9, Pages 1223: Oxidative Stress in Neurodegenerative Diseases: From Preclinical Studies to Clinical Applications Journal of Clinical Medicine doi: 10.3390/jcm9041223 Authors: Andrea Tarozzi Oxidative stress plays an important role in the pathogenesis of several different neurodegenerative diseases (NDDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease, amyotrophic lateral sclerosis (ALS) and multiple sclerosis...
Fri Apr 24, 2020 03:00
JFMK, Vol. 5, Pages 27: Physiological, Psychological and Performance-Related Changes Following Physique Competition: A Case-Series Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5020027 Authors: Jaymes M. Longstrom Lauren M. Colenso-Semple Brian J. Waddell Gianna Mastrofini Eric T. Trexler Bill I. Campbell The purpose of this case-series was to evaluate the physiological, psychological and performance-related changes that occur during the postcompetition...
Sat Apr 25, 2020 03:00
Life, Vol. 10, Pages 49: Rocket Science: The Effect of Spaceflight on Germination Physiology, Ageing, and Transcriptome of Eruca sativa Seeds Life doi: 10.3390/life10040049 Authors: Jake O. Chandler Fabian B. Haas Safina Khan Laura Bowden Michael Ignatz Eugenia M. A. Enfissi Frances Gawthrop Alistair Griffiths Paul D. Fraser Stefan A. Rensing Gerhard Leubner-Metzger In the ‘Rocket Science’ project, storage of Eruca sativa (salad rocket)...
Fri Apr 24, 2020 03:00
Life, Vol. 10, Pages 50: Enigmatic Histamine Receptor H4 for Potential Treatment of Multiple Inflammatory, Autoimmune, and Related Diseases Life doi: 10.3390/life10040050 Authors: Pakhuri Mehta Przemysław Miszta Przemysław Rzodkiewicz Olga Michalak Piotr Krzeczyński Sławomir Filipek The histamine H4 receptor, belonging to the family of G-protein coupled receptors, is an increasingly attractive drug target. It plays an indispensable role in many cellular pathways, and numerous...
Fri Apr 24, 2020 03:00
Life, Vol. 10, Pages 48: Maternal Obesity Modulates Expression of Satb2 in Hypothalamic VMN of Female Offspring Life doi: 10.3390/life10040048 Authors: Kelly A. Glendining Lorryn C. Fisher Christine L. Jasoni Maternal obesity during pregnancy is associated with a greater risk of poor health outcomes in offspring, including obesity, metabolic disorders, and anxiety, however the incidence of these diseases differs for males and females. Similarly, animal models of maternal obesity...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 210: Assessing Clinical Embryology Research: A Global Bibliometric Analysis
Medicina, Vol. 56, Pages 210: Assessing Clinical Embryology Research: A Global Bibliometric Analysis Medicina doi: 10.3390/medicina56050210 Authors: Simopoulou Sfakianoudis Maziotis Rapani Giannelou Pantou Anifandis Bakas Vlahos Pantos Koutsilieris Background and Objectives: The evaluative strength of available bibliometric tools in the field of clinical embryology has never been examined in the literature. The aim is to bring insight regarding...
Sun Apr 26, 2020 03:00
Medicina, Vol. 56, Pages 207: Clinical and Prognostic Significance of TZAP Expression in Cervical Cancer Medicina doi: 10.3390/medicina56050207 Authors: Park Park Shin Lee Background and Objectives: Telomeric zinc finger-associated protein (TZAP) is a telomere-associated factor that was previously called ZBTB48. This protein binds preferentially to long telomeres, competing with telomeric repeat factors 1 and 2. Genetic changes in TZAP may be associated with cancer pathogenesis;...
Sat Apr 25, 2020 03:00
Medicina, Vol. 56, Pages 208: Obstructive Sleep Apnea: A View from the Back Door Medicina doi: 10.3390/medicina56050208 Authors: Dragonieri Bikov Obstructive sleep apnea (OSA) is a common disease that may affect up to 50% of the adult population and whose incidence continues to rise, as well as its health and socio-economic burden. OSA is a well-known risk factor for motor vehicles accidents and decline in work performance and it is frequently accompanied by cardiovascular diseases....
Sat Apr 25, 2020 03:00
Medicina, Vol. 56, Pages 209: Transforaminal Epiduroscopic Laser Ablation for Removal of a Postlaminectomy Synovial Cyst: A Case Report Medicina doi: 10.3390/medicina56050209 Authors: Kang Kim Lee Park Background: Synovial cysts rarely occur after a laminectomy and are difficult to detect if there are no symptoms; however, they can cause lower back pain or symptoms of radiculopathy. Various methods are used to treat synovial cysts. Here, we will introduce the first case...
Sat Apr 25, 2020 03:00
Medicina, Vol. 56, Pages 206: Implications of Hepatitis E Virus in Blood Transfusions, Hemodialysis, and Solid Organ Transplants Medicina doi: 10.3390/medicina56050206 Authors: Essam M. Janahi Saba F. D. Parkar Sakina Mustafa Zaki M. Eisa Hepatitis E Virus (HEV) is emerging as the primary cause of acute viral hepatitis in humans. The virus is commonly transmitted by the fecal–oral route via contaminated water in endemic regions or through the consumption of inadequately...
Sat Apr 25, 2020 03:00
Medicina, Vol. 56, Pages 204: Targeted Intervention to Reduce Smoking among People with Severe Mental Illness: Implementation of a Smoking Cessation Intervention in an Inpatient Mental Health Setting Medicina doi: 10.3390/medicina56040204 Authors: Julia M. Lappin Dennis Thomas Jackie Curtis Stephen Blowfield Mike Gatsi Gareth Marr Ryan Courtney Background and Objectives: Smoking and smoking-related harms are highly prevalent among people with severe mental illness....
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 201: Pediatric Scoliosis Surgery—A Comprehensive Analysis of Treatment-Specific Variables and Trends in Latvia Medicina doi: 10.3390/medicina56040201 Authors: Julian M. Rüwald Janis Upenieks Janis Ositis Alexander Pycha Yuval Avidan Anna L. Rüwald Robin L. Eymael Frank A. Schildberg Background and Objectives: There are currently no data available regarding pediatric scoliosis surgery in Latvia. The aim of this article is to present treatment...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 205: Trauma Coagulopathy and Its Outcomes Medicina doi: 10.3390/medicina56040205 Authors: Gabriele Savioli Iride Francesca Ceresa Sarah Macedonio Sebastiano Gerosa Mirko Belliato Giorgio Antonio Iotti Sabino Luzzi Mattia Del Maestro Gianluca Mezzini Alice Giotta Lucifero Elvis Lafe Anna Simoncelli Federica Manzoni Lorenzo Cobianchi Mario Mosconi Fabrizio Cuzzocrea Francesco Benazzo Ricevuti Giovanni Maria Antonietta...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 197: Prevalence of Periodontal Disease among Obese Young Adult Population in Saudi Arabia—A Cross-Sectional Study Medicina doi: 10.3390/medicina56040197 Authors: Julie Toby Thomas Toby Thomas Masood Ahmed Karthiga Kannan S Zoha Abdullah Sara Ayid Alghamdi Betsy Joseph Background and objectives: We aimed to assess the prevalence of periodontal disease among obese young adults in Saudi Arabia and to analyze the association between different body...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 202: Active Pulmonary Tuberculosis Triggered by Interferon Beta-1b Therapy of Multiple Sclerosis: Four Case Reports and a Literature Review Medicina doi: 10.3390/medicina56040202 Authors: Carmen Adella Sirbu Elena Dantes Cristina Florentina Plesa Any Docu Axelerad Minerva Claudia Ghinescu In this paper, we reported on four cases of severe pulmonary active tuberculosis in patients with multiple sclerosis (MS) undergoing interferon beta-1b (IFNβ-1b)...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 200: Palatal Wound Healing with Primary Intention in a Rat Model—Histology and Immunohistomorphometry Medicina doi: 10.3390/medicina56040200 Authors: Liat Chaushu Marina Rahmanov Gavrielov Gavriel Chaushu Marilena Vered Background and objectives: Subepithelial connective tissue graft (SCTG) from the palate has been considered as the “gold standard” for the treatment of deep gingival recessions. A single-incision technique was reported...
Fri Apr 24, 2020 03:00
Medicina, Vol. 56, Pages 203: Timing of Endotracheal Intubation in Patients with Fulminant Enterovirus 71 Infection Medicina doi: 10.3390/medicina56040203 Authors: Chen Ju Wei Hsieh Liu Wu Wang Background and objective: Enterovirus 71 (EV 71) infections may result in the rapid progression of cardiopulmonary failure. Early endotracheal intubation is considered to be of primary importance. However, the appropriate timing for this is still not known. The aim of...
Fri Apr 24, 2020 03:00
Membranes, Vol. 10, Pages 80: Microtube Array Membrane (MTAM)-Based Encapsulated Cell Therapy for Cancer Treatment Membranes doi: 10.3390/membranes10050080 Authors: Chee Ho Chew Chih-Wei Lee Wan-Ting Huang Li-Wei Cheng Amanda Chen Tsai-Mu Cheng Yen-Lin Liu Chien-Chung Chen The treatment of cancer has evolved significantly in recent years with a strong focus on immunotherapy. Encapsulated Cell Therapy (ECT) for immunotherapy-based anti-cancer treatment is a unique...
Sun Apr 26, 2020 03:00
Membranes, Vol. 10, Pages 79: Assessing the Performance of Thin-Film Nanofiltration Membranes with Embedded Montmorillonites Membranes doi: 10.3390/membranes10050079 Authors: Micah Belle Marie Yap Ang Amira Beatriz Gaces Deang Ruth R. Aquino Blessie A. Basilia Shu-Hsien Huang Kueir-Rarn Lee Juin-Yih Lai In this study, the basal spacing of montmorillonite (MMT) was modified through ion exchange. Two kinds of MMT were used: sodium-modified MMT (Na-MMT) and organo-modified...
Sun Apr 26, 2020 03:00
Metabolites, Vol. 10, Pages 172: Developmental Signatures of Microbiota-Derived Metabolites in the Mouse Brain Metabolites doi: 10.3390/metabo10050172 Authors: Swann Spitzer Diaz Heijtz The gut microbiome is recognized to exert a wide-ranging influence on host health and disease, including brain development and behavior. Commensal bacteria can produce bioactive molecules that enter the circulation and impact host physiology and homeostasis. However, little is known about the...
Sat Apr 25, 2020 03:00
Metabolites, Vol. 10, Pages 170: Identification of Metabolic Alterations in Breast Cancer Using Mass Spectrometry-Based Metabolomic Analysis Metabolites doi: 10.3390/metabo10040170 Authors: Sili Fan Muhammad Shahid Peng Jin Arash Asher Jayoung Kim Breast cancer (BC) is a major global health issue and remains the second leading cause of cancer-related death in women, contributing to approximately 41,760 deaths annually. BC is caused by a combination of genetic and environmental...
Fri Apr 24, 2020 03:00
Metabolites, Vol. 10, Pages 171: On the Use of Correlation and MI as a Measure of Metabolite—Metabolite Association for Network Differential Connectivity Analysis Metabolites doi: 10.3390/metabo10040171 Authors: Sanjeevan Jahagirdar Edoardo Saccenti Metabolite differential connectivity analysis has been successful in investigating potential molecular mechanisms underlying different conditions in biological systems. Correlation and Mutual Information (MI) are two of the most common...
Fri Apr 24, 2020 03:00
Metabolites, Vol. 10, Pages 168: Distinguishing NASH Histological Severity Using a Multiplatform Metabolomics Approach Metabolites doi: 10.3390/metabo10040168 Authors: George N. Ioannou G. A. Nagana Gowda Danijel Djukovic Daniel Raftery Nonalcoholic fatty liver disease (NAFLD) is categorized based on histological severity into nonalcoholic fatty liver (NAFL) or nonalcoholic steatohepatitis (NASH). We used a multiplatform metabolomics approach to identify metabolite markers and...
Fri Apr 24, 2020 03:00
Metabolites, Vol. 10, Pages 169: Mechanism of Chronic Kidney Disease Progression and Novel Biomarkers: A Metabolomic Analysis of Experimental Glomerulonephritis Metabolites doi: 10.3390/metabo10040169 Authors: Kyoung Hee Han Bora Kim Sang Chun Ji Hee Gyung Kang Hae Il Cheong Joo-Youn Cho Il-Soo Ha While a complex network of cellular and molecular events is known to be involved in the pathophysiological mechanism of chronic kidney disease (CKD), the divergence point...
Fri Apr 24, 2020 03:00
MPs, Vol. 3, Pages 30: Combined Fluorescence-Based in Vitro Assay for the Simultaneous Detection of Cell Viability and Alkaline Phosphatase Activity during Osteogenic Differentiation of Osteoblast Precursor Cells Methods and Protocols doi: 10.3390/mps3020030 Authors: Wilkesmann Westhauser Fellenberg Novel bone substitute materials need to be evaluated in terms of their osteogenic differentiation capacity and possible unwanted cytotoxic effects in order to identify promising...
Sun Apr 26, 2020 03:00
Microorganisms, Vol. 8, Pages 625: Kinetics and New Mechanism of Azoxystrobin Biodegradation by an Ochrobactrum anthropi Strain SH14 Microorganisms doi: 10.3390/microorganisms8050625 Authors: Yanmei Feng Wenping Zhang Shimei Pang Ziqiu Lin Yuming Zhang Yaohua Huang Pankaj Bhatt Shaohua Chen Azoxystrobin is one of the most popular strobilurin fungicides, widely used in agricultural fields for decades.Extensive use of azoxystrobin poses a major threat to ecosystems....
Sun Apr 26, 2020 03:00
Microorganisms, Vol. 8, Pages 628: New Insights into the Oenological Significance of Candida zemplinina: Impact of Selected Autochthonous Strains on the Volatile Profile of Apulian Wines Microorganisms doi: 10.3390/microorganisms8050628 Authors: Pasquale Russo Maria Tufariello Raffaela Renna Mariana Tristezza Marco Taurino Lorenzo Palombi Vittorio Capozzi Carlo G. Rizzello Francesco Grieco In this investigation, we explored the oenological significance of Candida...
Sun Apr 26, 2020 03:00
Microorganisms, Vol. 8, Pages 621: Inhibition of Pro-Inflammatory Cytokines by Metabolites of Streptomycetes—A Potential Alternative to Current Anti-Inflammatory Drugs? Microorganisms doi: 10.3390/microorganisms8050621 Authors: Jiří Hrdý Lenka Súkeníková Petra Petrásková Olga Novotná David Kahoun Miroslav Petříček Alica Chroňáková Kateřina Petříčková Current treatment of chronic diseases includes, among others, application of cytokines, monoclonal antibodies, cellular...
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 627: Methodical Considerations and Resistance Evaluation Against Fusarium graminearum and F. culmorum Head Blight in Wheat. Part 3. Susceptibility Window and Resistance Expression Microorganisms doi: 10.3390/microorganisms8050627 Authors: György Tóth Varga Mesterhazy Flowering is the most favorable host stage for Fusarium infection in wheat, which is called the susceptibility window (SW). It is not known how long it takes, how it changes in...
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 622: Crosstalk between the Type VI Secretion System and the Expression of Class IV Flagellar Genes in the Pseudomonas fluorescens MFE01 Strain Microorganisms doi: 10.3390/microorganisms8050622 Authors: Mathilde Bouteiller Mathias Gallique Yvann Bourigault Artemis Kosta Julie Hardouin Sebastien Massier Yoan Konto-Ghiorghi Corinne Barbey Xavier Latour Andréa Chane Marc Feuilloley Annabelle Merieau Type VI secretion systems...
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 623: Framework as a Service, FaaS: Personalized Prebiotic Development for Infants with the Elements of Time and Parametric Modelling of in vitro Fermentation Microorganisms doi: 10.3390/microorganisms8050623 Authors: Lam Cheng Yang Lin You Chiou Kwan Cheung We proposed a framework with parametric modeling to obtain biological relevant parameters from the total probiotic growth pattern and metabolite production curves. The lag...
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 624: Evolution and Genetic Diversity of Primate Cytomegaloviruses Microorganisms doi: 10.3390/microorganisms8050624 Authors: Rachele Cagliani Diego Forni Alessandra Mozzi Manuela Sironi Cytomegaloviruses (CMVs) infect many mammals, including humans and non–human primates (NHPs). Human cytomegalovirus (HCMV) is an important opportunistic pathogen among immunocompromised patients and represents the most common infectious cause of birth defects....
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 620: Antibiofilm Activity of a Trichoderma Metabolite against Xanthomonas campestris pv. campestris, Alone and in Association with a Phage Microorganisms doi: 10.3390/microorganisms8050620 Authors: Marina Papaianni Annarita Ricciardelli Andrea Fulgione Giada d’Errico Astolfo Zoina Matteo Lorito Sheridan L. Woo Francesco Vinale Rosanna Capparelli Biofilm protects bacteria against the host’s immune system and adverse environmental...
Sat Apr 25, 2020 03:00
Microorganisms, Vol. 8, Pages 626: Antimicrobial Peptides from Rat-Tailed Maggots of the Drone Fly Eristalis tenax Show Potent Activity against Multidrug-Resistant Gram-Negative Bacteria Microorganisms doi: 10.3390/microorganisms8050626 Authors: Hirsch Wiesner Bauer Marker Vogel Hammann Vilcinskas The spread of multidrug-resistant Gram-negative bacteria is an increasing threat to human health, because novel compound classes for the development of antibiotics...
Sat Apr 25, 2020 03:00
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