Related ArticlesAn Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients. JNCI Cancer Spectr. 2020 Apr;4(2):pkz094 Authors: Chau NG, Ma C, Danga K, Al-Sayegh H, Nardi V, Barrette R, Lathan CS, DuBois SG, Haddad RI, Shapiro GI, Sallan SE, Dhar A, Nelson JJ, French CA Abstract Background: NUT midline carcinoma, renamed NUT carcinoma (NC), is an aggressive squamous...
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Related ArticlesDystrophic Calcification in the Oral Cavity Resulting in Mechanical Dysphagia: A Case Report and Review of Calcification in the Head and Neck Region. Cureus. 2020 Mar 30;12(3):e7469 Authors: Kumar G A, Deora SS Abstract Soft tissue calcifications in the oral cavity and maxillofacial region are most often detected as incidental findings on routine radiographic examination. But sometimes these soft tissue calcifications can be serious...
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Related ArticlesPredicting the risk of sarcopenia in elderly patients with patellar fracture: development and assessment of a new predictive nomogram. PeerJ. 2020;8:e8793 Authors: Chen YS, Cai YX, Kang XR, Zhou ZH, Qi X, Ying CT, Zhang YP, Tao J Abstract Purpose: To develop a risk prediction model for postoperative sarcopenia in elderly patients with patellar fractures in China. Patients and methods: We conducted a community survey of patients...
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Related ArticlesMiRNAs in Radiotherapy Resistance of Nasopharyngeal Carcinoma. J Cancer. 2020;11(13):3976-3985 Authors: Tian Y, Tang L, Yi P, Pan Q, Han Y, Shi Y, Rao S, Tan S, Xia L, Lin J, Oyang L, Tang Y, Liang J, Luo X, Liao Q, Wang H, Zhou Y Abstract Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors of the head and neck in Southeast Asia and southern China. Although the comprehensive treatment based on intensity-modulated...
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Related ArticlesmiR-93-5p enhances migration and invasion by targeting RGMB in squamous cell carcinoma of the head and neck. J Cancer. 2020;11(13):3871-3881 Authors: Zhang S, He Y, Liu C, Li G, Lu S, Jing Q, Chen X, Ma H, Zhang D, Wang Y, Huang D, Tan P, Chen J, Zhang X, Liu Y, Qiu Y Abstract Invasion and metastasis represent the primary causes of therapeutic failure in patients diagnosed with squamous cell carcinoma of the head and neck (SCCHN)....
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Related ArticlesSwallow Motor Pattern Is Modulated by Fixed or Stochastic Alterations in Afferent Feedback. Front Hum Neurosci. 2020;14:112 Authors: King SN, Shen TY, Musselwhite MN, Huff A, Reed MD, Poliacek I, Howland DR, Dixon W, Morris KF, Bolser DC, Iceman KE, Pitts T Abstract Afferent feedback can appreciably alter the pharyngeal phase of swallow. In order to measure the stability of the swallow motor pattern during several types of alterations...
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Related ArticlesManagement of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat. Cancers (Basel). 2020 Apr 15;12(4): Authors: Perri F, Longo F, Caponigro F, Sandomenico F, Guida A, Della Vittoria Scarpati G, Ottaiano A, Muto P, Ionna F Abstract : Head and neck squamous cell carcinomas (HNSCCs) are a very heterogeneous group of malignancies arising from the upper aerodigestive tract. They show different clinical behaviors...
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Related ArticlesThe Impact of Locoregional Treatment on Response to Nivolumab in Advanced Platinum Refractory Head and Neck Cancer: The Need Trial. Vaccines (Basel). 2020 Apr 20;8(2): Authors: Botticelli A, Mezi S, Pomati G, Sciattella P, Cerbelli B, Roberto M, Mammone G, Cirillo A, Cassano A, Di Dio C, Cortellini A, Pizzuti L, Ronzino G, Salati M, Vici P, Polimeni A, Merlano MC, Nuti M, Marchetti P Abstract BACKGROUND: Previous locoregional treatment...
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Related ArticlesHuman Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review. Pathogens. 2020 Apr 20;9(4): Authors: Fernandes Q, Gupta I, Vranic S, Al Moustafa AE Abstract Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, LMP2A and EBNA1), play...
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Related ArticlesAutochthonous Cases of Mucosal Leishmaniasis in Northeastern Italy: Clinical Management and Novel Treatment Approaches. Microorganisms. 2020 Apr 18;8(4): Authors: Gaspari V, Zaghi I, Macrì G, Patrizi A, Salfi N, Locatelli F, Carra E, Re MC, Varani S Abstract Mucosal leishmaniasis (ML) is a rare clinical variant of tegumentary leishmaniasis in Mediterranean Europe. Here we report on three autochthonous cases of head and neck ML in...
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Related ArticlesThe noise navigator for MRI-guided radiotherapy: an independent method to detect physiological motion. Phys Med Biol. 2020 Apr 24;: Authors: Navest RJM, Mandija S, Zijlema SE, Stemkens B, Andreychenko A, Lagendijk JJW, Van den Berg CAT Abstract Motion is problematic during radiotherapy as it could lead to potential underdosage of the tumor, and/or overdosage in organs-at-risk. A solution is adaptive radiotherapy guided by magnetic...
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Related ArticlesHead and neck oncology during the COVID-19 pandemic: Reconsidering traditional treatment paradigms in light of new surgical and other multilevel risks. Oral Oncol. 2020 Apr 06;105:104684 Authors: Day AT, Sher DJ, Lee RC, Truelson JM, Myers LL, Sumer BD, Stankova L, Tillman BN, Hughes RS, Khan SA, Gordin EA Abstract The COVID-19 pandemic demands reassessment of head and neck oncology treatment paradigms. Head and neck cancer (HNC) patients...
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Related ArticlesPrognostic and clinicopathological significance of PD-L1 overexpression in oral squamous cell carcinoma: A systematic review and comprehensive meta-analysis. Oral Oncol. 2020 Apr 21;106:104722 Authors: Lenouvel D, González-Moles MÁ, Ruiz-Ávila I, Gonzalez-Ruiz L, Gonzalez-Ruiz I, Ramos-García P Abstract BACKGROUND: The presence of Programmed Death-Ligand 1 protein (PD-L1) in oral squamous cell carcinoma (OSCC) may indicate an ability...
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Related ArticlesNovel anti-EGFR scFv human antibody-conjugated immunoliposomes enhance chemotherapeutic efficacy in squamous cell carcinoma of head and neck. Oral Oncol. 2020 Apr 21;106:104689 Authors: Wang YP, Liu IJ, Chung MJ, Wu HC Abstract BACKGROUND AND OBJECTIVES: Squamous cell carcinoma of head and neck (SCCHN) is the fifth most prevalent cancer worldwide. Because the anatomical complexity of this region, complete surgical resection is often...
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Related ArticlesEndoscopic Transcanal Removal of External Auditory Canal Osteomas. Biomed J. 2020 Apr 21;: Authors: Chen CK, Chang KP, Chien CY, Hsieh LC Abstract BACKGROUND: External auditory canal (EAC) osteomas are rare, slow-growing benign neoplasms. Microscopic surgical excision had been reported for symptomatic osteomas. However, there was no study published on the feasibility of transcanal endoscopic ear surgery (TEES) for EAC osteoma. In...
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Related ArticlesEndoscopic Anterior Skull Base Reconstruction: A Meta-Analysis and Systematic Review of Graft Type. World Neurosurg. 2020 Apr 21;: Authors: Abiri A, Abiri P, Goshtasbi K, Lehrich BM, Sahyouni R, Hsu FP, Cadena G, Kuan EC Abstract OBJECTIVE: The influence of graft type (non-autologous versus autologous) on surgical outcomes in endoscopic anterior skull base (EASB) reconstruction is not well-understood. This review systematically evaluated...
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Related ArticlesPilot Study of Combined Aerobic and Resistance Exercise on Fatigue for Patients with Head and Neck Cancer: Inflammatory and Epigenetic Changes. Brain Behav Immun. 2020 Apr 21;: Authors: Xiao C, Beitler JJ, Higgins KA, Chico CE, Withycombe JS, Zhu Y, Zhao H, Lin IH, Li F, Jeon S, Irwin M, Bruner DW, Miller AH, Gary R Abstract This pilot study examined whether a combined aerobic resistance exercise program reduced fatigue and the potential...
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Related ArticlesNanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session. J Control Release. 2020 Apr 21;: Authors: Deken MM, Kijanka MM, Hernández IB, Slooter MD, de Bruijn HS, van Diest PJ, van Bergen En Henegouwen PMP, Lowik CWGM, Robinson DJ, Vahrmeijer AL, Oliveira S Abstract RATIONALE: A substantial number of breast cancer patients with...
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Related ArticlesBioabsorbable Microplates as an External Stent for Suprastomal Collapse: A Retrospective Review. Laryngoscope. 2020 Apr 24;: Authors: Jayawardena ADL, Burks CA, Hartnick CJ Abstract OBJECTIVE/HYPOTHESIS: To assess the long-term decannulation outcomes of bioresorbable microplates as an external stent for pediatric tracheostomy patients with suprastomal collapse. STUDY DESIGN: Retrospective cohort study. METHODS:...
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Related ArticlesImmunotherapy of solid tumors: how safely treat the patients. Pol Arch Intern Med. 2020 Apr 24;: Authors: Domagała-Kulawik J, Leszek P, Owczarek W, Rawa T, Stelmachowska-Banaś M, Rutkowski P Abstract Immunotherapy with immune checkpoint inhibitors (ICIs) was shown to improve survival of patients with solid tumors like: melanoma, renal carcinoma, non-small cell lung cancer, cutaneous carcinomas or head and neck carcinoma. However,...
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Related ArticlesTransition to a Virtual Multidisciplinary Tumor Board during the COVID-19 Pandemic: The University of Pittsburgh Experience. Head Neck. 2020 Apr 24;: Authors: Dharmarajan H, Anderson JL, Kim S, Sridharan S, Duvvuri U, Ferris RL, Solari MG, Clump DA, Skinner HD, Ohr JP, Zandberg DP, Branstetter B, Hughes MA, Traylor KS, Seethala R, Chiosea SI, Nilsen ML, Johnson JT, Kubik MW Abstract Multidisciplinary conferences (MDC) are an important...
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Related ArticlesShould we wait or not? The preferable option for patients with stage IV oral cancer in COVID-19 pandemic. Head Neck. 2020 Apr 24;: Authors: Bhattacharjee A, Patil VM, Dikshit R, Prabhash K, Singh A, Chaturvedi P Abstract BACKGROUND: The coronavirus infection is rapidly spreading putting a strain on healthcare services across the globe. Oral cancer patients are susceptible often immunosuppressed due to the disease and/or the treatment...
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Related ArticlesAn Ethical Framework for Head and Neck Cancer Care Impacted by COVID-19. Head Neck. 2020 Apr 24;: Authors: Shuman AG, Campbell BH, AHNS Ethics & Professionalism Service Abstract The COVID-19 pandemic has upended head and neck cancer care delivery in ways unforeseen and unprecedented. The impact of these changes parallels other fields in oncology, but is disproportionate due to protective measures and limitations on potentially...
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Related ArticlesHandling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement. Allergy. 2020 Apr 24;: Authors: Klimek L, Jutel M, Akdis C, Bousquet J, Akdis M, Bachert C, Agache I, Ansotegui I, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Giacco SD, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Melen E, Mullol J, Naclerio R, Ohta...
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Related ArticlesTracheostomy guidelines developed at a large academic medical center during the COVID-19 pandemic. Head Neck. 2020 Apr 24;: Authors: David AP, Russell MD, El-Sayed IH, Russell MS Abstract BACKGROUND: During the SARS-CoV-2 pandemic, tracheostomy may be required for COVID-19 patients requiring long term ventilation in addition to other conditions such as airway compromise from head and neck cancer. As an aerosol generating procedure,...
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Related ArticlesThe impact of Covid-19 0n Head and Neck Surgery, Education and training. Head Neck. 2020 Apr 24;: Authors: Shah JP PMID: 32329925 [PubMed - as supplied by publisher]
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Related ArticlesPotential Impact of the COVID-19 Pandemic on Financial Toxicity in Cancer Survivors. Head Neck. 2020 Apr 24;: Authors: Baddour K, Kudrick LD, Neopaney A, Sabik LM, Peddada SD, Nilsen ML, Johnson JT, Ferris RL, Mady LJ Abstract BACKGROUND: In the context of COVID-19, cancer survivors represent a particularly vulnerable population that may be "doubly hit" both by costs of cancer treatment and financial strain imposed by the pandemic....
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Related ArticlesEarly Institutional Head and Neck Oncologic and Microvascular Surgery Practice Patterns Across the United States During the SARS-CoV-2 (COVID19) Pandemic. Head Neck. 2020 Apr 24;: Authors: Patel RJ, Kejner A, McMullen C Abstract BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic has caused rapid changes in head and neck cancer (HNC) care. "Real-time" methods to monitor practice patterns can optimize provider safety and patient care. ...
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Related ArticlesTracheostomy Protocols during COVID-19 Pandemic. Head Neck. 2020 Apr 24;: Authors: Heyd CP, Desiato VM, Nguyen SA, O'Rourke AK, Clemmens CS, Awad MI, Worley ML, Day TA Abstract BACKGROUND: The COVID-19 pandemic has resulted in the implementation of rapidly changing protocols and guidelines related to the indications and perioperative precautions and protocols for tracheotomy. The purpose of this study was to evaluate current guidelines...
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Related ArticlesPredictors of Weight Loss in Patients With Head and Neck Cancer Receiving Radiation or Concurrent Chemoradiation Treated at a Tertiary Cancer Center. Nutr Clin Pract. 2020 Apr 24;: Authors: Pandit P, Patil R, Palwe V, Yasam VR, Nagarkar R Abstract BACKGROUND: Radiation therapy (RT) has remained the mainstay treatment approach for head and neck cancers. Weight loss due to tumor or tumor-related factors remains a major health issue...
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Related ArticlesWhat ENT doctors should know about COVID-19 contagion risks. Head Neck. 2020 Apr 24;: Authors: Meccariello G, Gallo O PMID: 32329539 [PubMed - as supplied by publisher]
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Related ArticlesDose-volume histogram analysis and clinical evaluation of knowledge-based plans with manual objective constraints for pharyngeal cancer. J Radiat Res. 2020 Apr 24;: Authors: Uehara T, Monzen H, Tamura M, Ishikawa K, Doi H, Nishimura Y Abstract The present study aimed to evaluate whether knowledge-based plans (KBP) from a single optimization could be used clinically, and to compare dose-volume histogram (DVH) parameters and plan quality...
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Related ArticlesKRT6A Promotes EMT and Cancer Stem Cell Transformation in Lung Adenocarcinoma. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820921248 Authors: Yang B, Zhang W, Zhang M, Wang X, Peng S, Zhang R Abstract AIM: Keratin 6A is a type II cytokeratin which is important in forming nail bed, filiform papillae, the epithelial lining of oral mucosa, and esophagus; recently, keratin 6A was found hyperexpressed in different types of cancer....
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Related ArticlesSelf-reported olfactory loss associates with outpatient clinical course in Covid-19. Int Forum Allergy Rhinol. 2020 Apr 24;: Authors: Yan CH, Faraji F, Prajapati DP, Ostrander BT, DeConde AS Abstract BACKGROUND: Rapid spread of the SARS-CoV-2 virus has left many health systems around the world overwhelmed, forcing triaging of scarce medical resources. Identifying indicators of hospital admission for Covid-19 patients early in the...
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Related ArticlesSleep Apnea is Associated with Hearing Impairment: the Paris Prospective Study 3. Clin Otolaryngol. 2020 Apr 23;: Authors: Lisan Q, van Sloten TT, Climie RE, Boutouyrie P, Guibout C, Thomas F, Danchin N, Jouven X, Empana JP Abstract OBJECTIVES: Hearing impairment (HI) is a leading impairment worldwide and identifying modifiable risk factors of HI may have major public health implications. The aim of this study was to investigate the...
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Related ArticlesWho should perform the rhinopharyngeal swab in COVID-19 positive patients? Head Neck. 2020 Apr 24;: Authors: De Virgilio A, Pellini R, Mercante G, Ferreli F, Petruzzi G, Spriano G PMID: 32329138 [PubMed - as supplied by publisher]
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Related ArticlesDeveloping Classifications of Laryngeal Dysplasia: The Historical Basis. Adv Ther. 2020 Apr 23;: Authors: Hellquist H, Ferlito A, Mäkitie AA, Thompson LDR, Bishop JA, Agaimy A, Hernandez-Prera JC, Gnepp DR, Willems SM, Slootweg PJ, Rinaldo A Abstract During the last 60 years numerous significant attempts have been made to achieve a widely acceptable terminology and histological grading for laryngeal squamous intraepithelial lesions....
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Related ArticlesRecent and Emerging Therapies for Cutaneous Squamous Cell Carcinomas of the Head and Neck. Curr Treat Options Oncol. 2020 Apr 23;21(5):37 Authors: Varra V, Smile TD, Geiger JL, Koyfman SA Abstract OPINION STATEMENT: Cutaneous squamous cell carcinoma (cSCC) of the head and neck is typically managed with Mohs Micrographic Surgery (MMS) for cosmetic reasons. MMS also improves oncologic outcomes for high-risk tumors. Patients with certain...
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Related ArticlesTreatment of pulsatile tinnitus caused by anomalies of the sigmoid sinus wall via combined internal and external sigmoid sinus wall reconstruction with 3D temporal bone CT guidance. Eur Arch Otorhinolaryngol. 2020 Apr 23;: Authors: Wang D, Zhao Y, Tong B Abstract PURPOSE: The present analysis aims to describe a surgical approach wherein pulsatile tinnitus (PT) arising due to sigmoid sinus wall anomalies (SSWA) can be treated via combination...
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