Κυριακή 26 Απριλίου 2020

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Our Response to COVID-19 Is Male-Centric
We don’t know how the coronavirus may affect women and men differently, which prevents us from delivering appropriate and personalized care -- Read more on ScientificAmerican.com
Scientific American Blog Posts
13h
More Time Out in Nature is an Unexpected Benefit of the COVID-19 Sheltering Rules
Exploring the natural world can be restorative to mental health -- Read more on ScientificAmerican.com
Scientific American Blog Posts
22h
The Stars Could Help Unify Us
In a time of social distancing, looking to the skies might bring people closer together -- Read more on ScientificAmerican.com
Scientific American Blog Posts
1d
COVID-19: Potential Implications for Individuals with Substance Use Disorders
People who smoke tobacco or marijuana; vape; or use opioids or methamphetamine may be at higher risk of serious disease -- Read more on ScientificAmerican.com
Scientific American Blog Posts
1d
Prime Factorization as Verse
Creating poetry with the fundamental theorem of arithmetic -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
Life Inside the Extinction
These are startling times, but there's a way out -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
COVID-19 Will Hit the Elderly Even Harder in Developing Countries
The suffering will be unimaginable -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
Why COVID-19 Is a Special Danger to Otolaryngologists
Anosmia, or loss of smell, can be an early symptom—and that puts these ear, nose and throat physicians at risk -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
To Protect Black Americans from the Worst Impacts of COVID-19, Release Comprehensive Racial Data
Properly reported information is crucial for Black communities to recover from this crisis and transcend a history of exclusion    -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
Coronavirus Roundup for April 18-24
Here are pandemic news highlights for the week -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
A Birthday Message from the Hubble Telescope
I’m turning 30, and it’s been an amazing journey so far -- Read more on ScientificAmerican.com
Scientific American Blog Posts
2d
Real-time ultrasound-guided thoracentesis in the intensive care unit: prevalence of mechanical complications
Abstract Background The use of thoracic ultrasound during thoracentesis reduces complications. The aim of this study was to determine the prevalence of complications for real-time ultrasound-guided thoracentesis performed by intensivists. As a secondary objective, the change in oxygenation before and after the procedure was evaluated. Patients and methods ...
Latest Results for Critical Ultrasound Journal
14h
Τι σημαίνει κρυψίνους & πως μπορεί να σου ανοιχτεί;
Τι σημαίνει κρυψίνους: Επίθετο: κρυψίνους αρσενικό ή θηλυκό. -ουν (AM κρυψίνους, -ουν και -οος, -οον) 1. αυτός που αποκρύπτει τις σκέψεις, τις ιδέες ή τις πραγματικές προθέσεις του ή τις σκέψεις του 2. υποκριτής, ανειλικρινής, πανούργος («κρυψίνουν καὶ δολερὸν καὶ ἀπατεῶνα καὶ κλέπτην», αυτός/αυτή που προσποιείται Ετοιμολογία της λέξης κρυψίνους < αρχαία ελληνική κρυψίνους < κρύπτω + νοῦς Συγγενικές λέξεις κρυψίνοια Αλλιώς: απερίεργος, αδιάφορος, μυστικοπαθής Αγγλική […]
Ethernews.com
14h
Corrigendum to “ABCC8 genetic variants and risk of diabetes mellitus” [Gene 545 (2014) 198–204]
Publication date: Available online 25 April 2020Source: GeneAuthor(s): Polin Haghvirdizadeh, Monir Sadat Haerian, Pantea Haghvirdizadeh, Batoul Sadat Haerian
Gene
15h
Mutational and phenotypic expansion of <em>ATP1A3</em>-related disorders: Report of nine cases
Publication date: Available online 25 April 2020Source: GeneAuthor(s): Ponghatai Boonsimma, Marius Michael Gasser, Wiracha Netbaramee, Thanin Wechapinan, Chalurmpon Srichomthomg, Chupong Ittiwut, Matias Wagner, Martin Krenn, Fritz Zimprich, Angela Abicht, Saskia Biskup, Timo Roser, Ingo Borggraefe, Kanya Suphapeetiporn, Vorasuk Shotelersuk
Gene
1d
MGF-19E peptide promoted proliferation, differentiation and mineralization of MC3T3-E1 cell and promoted bone defect healing
Publication date: Available online 24 April 2020Source: GeneAuthor(s): Wenzhen Wei, Songcai Liu, Jie Song, Tianqi Feng, Rui Yang, Yunyun Cheng, Haoyang Li, Linlin Hao
Gene
1d
Effect of duck hepatitis A virus genotype 3 infection on glucose metabolism of Pekin ducklings and underlying mechanism
Publication date: Available online 24 April 2020Source: GeneAuthor(s): Suyun Liang, Jing Tang, Xiaoyan Wang, Zhiguo Wen, Ming Xie, Yongbao Wu, Shuisheng Hou, Dabing Zhang
Gene
1d
Elucidating the multi-drug resistance mechanism of <em>Enterococcus faecalis</em> V583: A gene interaction network analysis
Publication date: Available online 24 April 2020Source: GeneAuthor(s): Aniket Naha, Sravan Kumar Miryala, Reetika Debroy, Sudha Ramaiah, Anand Anbarasu
Gene
1d
Role of the translocase of the mitochondrial inner membrane in the import of tRNAs into mitochondria in <em>Trypanosoma brucei</em>
Publication date: Available online 24 April 2020Source: GeneAuthor(s): Muhammad Younas Khan Barozai, Minu Chaudhuri
Gene
1d
The ADAMTS9 gene is associated with mandibular retrusion in a Chinese population
Publication date: Available online 23 April 2020Source: GeneAuthor(s): Ying Cai, Zhenyu Ni, Weiting Chen, Yu Zhou
Gene
2d
Cancers, Vol. 12, Pages 1080: YM155-Adapted Cancer Cell Lines Reveal Drug-Induced Heterogeneity and Enable the Identification of Biomarker Candidates for the Acquired Resistance Setting
Cancers, Vol. 12, Pages 1080: YM155-Adapted Cancer Cell Lines Reveal Drug-Induced Heterogeneity and Enable the Identification of Biomarker Candidates for the Acquired Resistance Setting Cancers doi: 10.3390/cancers12051080 Authors: Michaelis Wass Reddin Voges Rothweiler Hehlgans Cinatl Mernberger Nist Stiewe Rödel Cinatl Jr. Survivin is a drug target and its suppressant YM155 a drug candidate mainly investigated for high-risk...
Cancers
15h
Cancers, Vol. 12, Pages 1079: Erratum: Berndsen, R.H., et al. Colorectal Cancer Growth Retardation through Induction of Apoptosis, Using an Optimized Synergistic Cocktail of Axitinib, Erlotinib, and Dasatinib, Cancers 2019, 11, 1878
Cancers, Vol. 12, Pages 1079: Erratum: Berndsen, R.H., et al. Colorectal Cancer Growth Retardation through Induction of Apoptosis, Using an Optimized Synergistic Cocktail of Axitinib, Erlotinib, and Dasatinib, Cancers 2019, 11, 1878 Cancers doi: 10.3390/cancers12051079 Authors: Berndsen Swier van Beijnum Nowak-Sliwinska The authors wish to make the following corrections to this paper[...]
Cancers
18h
Cancers, Vol. 12, Pages 1078: Clinical Variables Associated with PSA Response to Lutetium-177-PSMA ([177Lu]-PSMA-617) Radionuclide Treatment in Men with Metastatic Castration-Resistant Prostate Cancer
Cancers, Vol. 12, Pages 1078: Clinical Variables Associated with PSA Response to Lutetium-177-PSMA ([177Lu]-PSMA-617) Radionuclide Treatment in Men with Metastatic Castration-Resistant Prostate Cancer Cancers doi: 10.3390/cancers12051078 Authors: Moran Gadot Tima Davidson Margalit Aharon Eshetu G. Atenafu Avraham Malki Meital Levartovsky Akram Saad Liran Domachevsky Raanan Berger Raya Leibowitz Lutetium-177-PSMA ([177Lu]-PSMA-617), a radiolabeled...
Cancers
18h
Cancers, Vol. 12, Pages 1075: Overcoming Heterogeneity of Antigen Expression for Effective CAR T Cell Targeting of Cancers
Cancers, Vol. 12, Pages 1075: Overcoming Heterogeneity of Antigen Expression for Effective CAR T Cell Targeting of Cancers Cancers doi: 10.3390/cancers12051075 Authors: Sareetha Kailayangiri Bianca Altvater Malena Wiebel Silke Jamitzky Claudia Rossig Chimeric antigen receptor (CAR) gene-modified T cells (CAR T cells) can eradicate B cell malignancies via recognition of surface-expressed B lineage antigens. Antigen escape remains a major mechanism of relapse and is...
Cancers
19h
Cancers, Vol. 12, Pages 1076: Tumor-Infiltrating CD8 T Cells Predict Clinical Breast Cancer Outcomes in Young Women
Cancers, Vol. 12, Pages 1076: Tumor-Infiltrating CD8 T Cells Predict Clinical Breast Cancer Outcomes in Young Women Cancers doi: 10.3390/cancers12051076 Authors: Yong Won Jin Pingzhao Hu Young women with breast cancer have disproportionately poor clinical outcomes compared to their older counterparts. The underlying biological differences behind this age-dependent disparity are still unknown and warrant investigation. Recently, the tumor immune landscape has received much attention...
Cancers
19h
Cancers, Vol. 12, Pages 1074: Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal Cancers
Cancers, Vol. 12, Pages 1074: Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal Cancers Cancers doi: 10.3390/cancers12051074 Authors: Marco Benazzo Fabio Sovardi Lorenzo Preda Simone Mauramati Sergio Carnevale Giulia Bertino Francesca Berton Matteo Meroni Irene Herman Giuseppe Trisolini Patrizia Morbini Background: Preoperative imaging impacts treatment planning and prognosis in laryngeal cancers. We investigated the accuracy of...
Cancers
19h
Cancers, Vol. 12, Pages 1073: LINC00963 Promotes Cancer Stemness, Metastasis, and Drug Resistance in Head and Neck Carcinomas via ABCB5 Regulation
Cancers, Vol. 12, Pages 1073: LINC00963 Promotes Cancer Stemness, Metastasis, and Drug Resistance in Head and Neck Carcinomas via ABCB5 Regulation Cancers doi: 10.3390/cancers12051073 Authors: Lee Hsieh Fang Chu Liao Yu Yu Tsai Accumulating studies have indicated that long non-coding RNAs (lncRNAs) participate in the regulation of cancer stem cells (CSCs), which are crucial in tumor initiation, metastasis, relapse, and therapy resistance. In the...
Cancers
19h
Cancers, Vol. 12, Pages 1077: Cognitive Functions in Repeated Glioma Surgery
Cancers, Vol. 12, Pages 1077: Cognitive Functions in Repeated Glioma Surgery Cancers doi: 10.3390/cancers12051077 Authors: Capo Skrap Guarracino Isola Battistella Ius Tomasino Low-grade gliomas (LGG) are slow-growing brain tumors infiltrating the central nervous system which tend to recur, often with malignant degeneration after primary treatment. Re-operations are not always recommended due to an assumed higher risk of neurological and cognitive deficits....
Cancers
19h
Cancers, Vol. 12, Pages 1065: Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma
Cancers, Vol. 12, Pages 1065: Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma Cancers doi: 10.3390/cancers12051065 Authors: Fassmannová Sedlák Sedláček Špička Grantz Šašková Proteasome inhibitors are the backbone of multiple myeloma therapy. However, disease progression or early relapse occur due to development of resistance to the therapy. One important cause of resistance to proteasome inhibition is the so-called...
Cancers
1d
Cancers, Vol. 12, Pages 1071: Role of Calcium Signaling in Prostate Cancer Progression: Effects on Cancer Hallmarks and Bone Metastatic Mechanisms
Cancers, Vol. 12, Pages 1071: Role of Calcium Signaling in Prostate Cancer Progression: Effects on Cancer Hallmarks and Bone Metastatic Mechanisms Cancers doi: 10.3390/cancers12051071 Authors: Ardura Álvarez-Carrión Gutiérrez-Rojas Alonso Advanced prostate cancers that progress to tumor metastases are often considered incurable or difficult to treat. The etiology of prostate cancers is multi-factorial. Among other factors, de-regulation of calcium signals in prostate...
Cancers
1d
Cancers, Vol. 12, Pages 1067: Prognostic Value of SDF-1α Expression in Patients with Esophageal Squamous Cell Carcinoma Receiving Esophagectomy
Cancers, Vol. 12, Pages 1067: Prognostic Value of SDF-1α Expression in Patients with Esophageal Squamous Cell Carcinoma Receiving Esophagectomy Cancers doi: 10.3390/cancers12051067 Authors: Yen-Hao Chen Shau-Hsuan Li Hung-I Lu Chien-Ming Lo Stromal cell-derived factor-1&alpha; (SDF-1&alpha;) is a chemokine that has been reported to be involved in tumor progression in several malignancies. This study aimed to evaluate the crucial role of SDF-1&alpha; in patients...
Cancers
1d
Cancers, Vol. 12, Pages 1069: Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal Carcinoma
Cancers, Vol. 12, Pages 1069: Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal Carcinoma Cancers doi: 10.3390/cancers12051069 Authors: Kofler Borena Dudas Innerhofer Dejaco Steinbichler Widmann von Laer Riechelmann Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is a distinct subtype of head and neck cancer. Here, we investigated how frequently brushing remained high-risk (hr)-HPV...
Cancers
1d
Cancers, Vol. 12, Pages 1070: Novel Oncolytic Virus Armed with Cancer Suicide Gene and Normal Vasculogenic Gene for Improved Anti-Tumor Activity
Cancers, Vol. 12, Pages 1070: Novel Oncolytic Virus Armed with Cancer Suicide Gene and Normal Vasculogenic Gene for Improved Anti-Tumor Activity Cancers doi: 10.3390/cancers12051070 Authors: Jeong Yoo Here, we developed a novel oncolytic vaccinia virus (NOV) with the dual advantages of cancer selectivity and normal vessel reconstructive activity by replacing the viral thymidine kinase (vTk) and vaccinia growth factor (VGF) genes with genes encoding TNF-related apoptosis-inducing...
Cancers
1d
Cancers, Vol. 12, Pages 1066: Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion
Cancers, Vol. 12, Pages 1066: Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion Cancers doi: 10.3390/cancers12051066 Authors: Sara Monteiro-Reis Ana Lameirinhas Vera Miranda-Gonçalves Diana Felizardo Paula C. Dias Jorge Oliveira Inês Graça Céline S. Gonçalves Bruno M. Costa Rui Henrique Carmen Jerónimo Sirtuins are emerging players in cancer biology and...
Cancers
1d
Cancers, Vol. 12, Pages 1068: Oncobiosis and Microbial Metabolite Signaling in Pancreatic Adenocarcinoma
Cancers, Vol. 12, Pages 1068: Oncobiosis and Microbial Metabolite Signaling in Pancreatic Adenocarcinoma Cancers doi: 10.3390/cancers12051068 Authors: Borbála Kiss Edit Mikó Éva Sebő Judit Toth Gyula Ujlaki Judit Szabó Karen Uray Péter Bai Péter Árkosy Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents an unmet medical need....
Cancers
1d
Cancers, Vol. 12, Pages 1064: The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights
Cancers, Vol. 12, Pages 1064: The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights Cancers doi: 10.3390/cancers12051064 Authors: Sasaki Doukas Costa Vageli Cancers of the laryngopharynx represent the most devastating of the head and neck malignancies and additional risk factors are now epidemiologically linked to this disease. Using an in vivo model (Mus musculus C57Bl/6J), we provide novel evidence...
Cancers
1d
Cancers, Vol. 12, Pages 1072: Solving the Time- and Frequency-Multiplexed Problem of Constrained Radiofrequency Induced Hyperthermia
Cancers, Vol. 12, Pages 1072: Solving the Time- and Frequency-Multiplexed Problem of Constrained Radiofrequency Induced Hyperthermia Cancers doi: 10.3390/cancers12051072 Authors: Kuehne Oberacker Waiczies Niendorf Targeted radiofrequency (RF) heating induced hyperthermia has a wide range of applications, ranging from adjunct anti-cancer treatment to localized release of drugs. Focal RF heating is usually approached using time-consuming nonconvex optimization procedures...
Cancers
1d
Cancers, Vol. 12, Pages 1063: Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas
Cancers, Vol. 12, Pages 1063: Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas Cancers doi: 10.3390/cancers12051063 Authors: Melissa Santi Ana Katrina Mapanao Domenico Cassano Ylea Vlamidis Valentina Cappello Valerio Voliani Negative or positive HPV-associated Head and Neck Squamous Cell Carcinomas (HNSCCs) are high recurrence neoplasms usually resulting in a poor prognosis, mainly due to metastasis...
Cancers
1d
Cancers, Vol. 12, Pages 1062: FGF2 Induces Resistance to Nilotinib through MAPK Pathway Activation in KIT Mutated Melanoma
Cancers, Vol. 12, Pages 1062: FGF2 Induces Resistance to Nilotinib through MAPK Pathway Activation in KIT Mutated Melanoma Cancers doi: 10.3390/cancers12051062 Authors: Pauline Tétu Julie Delyon Jocelyne André Coralie Reger de Moura Malak Sabbah Ghanem E Ghanem Maxime Battistella Samia Mourah Céleste Lebbé Nicolas Dumaz KIT is a bona fide oncogene in a subset of melanoma and, ex vivo, KIT inhibitors are very efficient at killing KIT-mutant melanoma...
Cancers
1d

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